Primary Site >> Liver Cancer
Gene >> MAP2K4
| 1. | |||||||||||
| Journal: | Int J Oncol. 2002 Sep;21(3):553-9. | ||||||||||
| Title: | MEKK1 induces c-Jun complexes that act as negative regulators for cell survival and proliferation of HCC cells. | ||||||||||
| Author: | Komoda, Fumitake|Shino, Yuji|Hirano, Tatsuya|Okutomi, Yoshiyuki|Okamoto, Hideki|Hayashi, Yukio|Suyama, Takahito|Ebara, Masaaki|Saisho, Hiromitsu|Shirasawa, Hiroshi | ||||||||||
| PMID: | 12168099 | ||||||||||
| 2. | |||||||||||
| Journal: | Cancer Res. 2003 Dec 1;63(23):8271-7. | ||||||||||
| Title: | HIPK2 regulates transforming growth factor-beta-induced c-Jun NH(2)-terminal kinase activation and apoptosis in human hepatoma cells. | ||||||||||
| Author: | Hofmann, Thomas G|Stollberg, Nicole|Schmitz, M Lienhard|Will, Hans | ||||||||||
| PMID: | 14678985 | ||||||||||
| 3. | |||||||||||
| Journal: | Mol Carcinog. 2011 Aug;50(8):580-91. | ||||||||||
| Title: | Critical roles of cellular glutathione homeostasis and jnk activation in andrographolide-mediated apoptotic cell death in human hepatoma cells. | ||||||||||
| Author: | Ji, Lili|Shen, Kaikai|Jiang, Ping|Morahan, Grant|Wang, Zhengtao | ||||||||||
| PMID: | 21319226 | ||||||||||
| 4. | |||||||||||
| Journal: | PLoS One. 2014 Jan 22;9(1):e86537. | ||||||||||
| Title: | Licochalcone A suppresses migration and invasion of human hepatocellular carcinoma cells through downregulation of MKK4/JNK via NF-kappaB mediated urokinase plasminogen activator expression. | ||||||||||
| Author: | Tsai, Jen-Pi|Hsiao, Pei-Ching|Yang, Shun-Fa|Hsieh, Shu-Ching|Bau, Da-Tian|Ling, Chu-Liang|Pai, Chun-Li|Hsieh, Yi-Hsien | ||||||||||
| PMID: | 24466137 | ||||||||||
| 5. | |||||||||||
| Journal: | Mol Immunol. 2015 Dec;68(2 Pt C):671-83. | ||||||||||
| Title: | Toll-like receptor 4 signaling promotes invasion of hepatocellular carcinoma cells through MKK4/JNK pathway. | ||||||||||
| Author: | Dong, Yu-Qing|Lu, Chuan-Wei|Zhang, Lu|Yang, Jia|Hameed, Waqaar|Chen, Wei | ||||||||||
| PMID: | 26589455 | ||||||||||
| 6. | |||||||||||
| Journal: | Environ Toxicol. 2017 Nov;32(11):2360-2370. | ||||||||||
| Title: | beta-mangostin suppresses human hepatocellular carcinoma cell invasion through inhibition of MMP-2 and MMP-9 expression and activating the ERK and JNK pathways. | ||||||||||
| Author: | Huang, Chien-Feng|Teng, Ying-Hock|Lu, Fung-Jou|Hsu, Wen-Hung|Lin, Chia-Liang|Hung, Chia-Chen|Tung, Jai-Nien|Hsieh, Yi-Hsien|Liu, Chung-Jung | ||||||||||
| PMID: | 28722351 | ||||||||||
| 7. | |||||||||||
| Journal: | Environ Toxicol. 2018 Sep 6. | ||||||||||
| Title: | Synergistic antimetastatic effect of cotreatment with licochalcone A and sorafenib on human hepatocellular carcinoma cells through the inactivation of MKK4/JNK and uPA expression. | ||||||||||
| Author: | Wu, Min-Hua|Chiu, Yi-Fang|Wu, Wen-Jun|Wu, Pei-Lien|Lin, Ching-Yi|Lin, Chia-Liang|Hsieh, Yi-Hsien|Liu, Chung-Jung | ||||||||||
| PMID: | 30187994 | ||||||||||