Primary Site >> Liver Cancer
Gene >> MAP2K4
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|
|
Ref: MEKK1 induces c-Jun complexes that act as negative regulators for cell survival and proliferation of HCC cells. PMID: 12168099 |
Ref: HIPK2 regulates transforming growth factor-beta-induced c-Jun NH(2)-terminal kinase activation and apoptosis in human hepatoma cells. PMID: 14678985 |
Ref: Critical roles of cellular glutathione homeostasis and jnk activation in andrographolide-mediated apoptotic cell death in human hepatoma cells. PMID: 21319226 |
Ref: Licochalcone A suppresses migration and invasion of human hepatocellular carcinoma cells through downregulation of MKK4/JNK via NF-kappaB mediated urokinase plasminogen activator expression. PMID: 24466137 |
Ref: Toll-like receptor 4 signaling promotes invasion of hepatocellular carcinoma cells through MKK4/JNK pathway. PMID: 26589455 |
Ref: beta-mangostin suppresses human hepatocellular carcinoma cell invasion through inhibition of MMP-2 and MMP-9 expression and activating the ERK and JNK pathways. PMID: 28722351 |
Ref: Synergistic antimetastatic effect of cotreatment with licochalcone A and sorafenib on human hepatocellular carcinoma cells through the inactivation of MKK4/JNK and uPA expression. PMID: 30187994 |