Primary Site >> Colorectal Cancer
Gene >> MAP2K4
| 1. | |||||||||||
| Journal: | Cancer Res. 1998 Jun 1;58(11):2339-42. | ||||||||||
| Title: | Alterations in pancreatic, biliary, and breast carcinomas support MKK4 as a genetically targeted tumor suppressor gene. | ||||||||||
| Author: | Su, G H|Hilgers, W|Shekher, M C|Tang, D J|Yeo, C J|Hruban, R H|Kern, S E | ||||||||||
| PMID: | 9622070 | ||||||||||
| 2. | |||||||||||
| Journal: | Cancer Res. 1999 May 15;59(10):2445-50. | ||||||||||
| Title: | Activated Ki-Ras suppresses 12-O-tetradecanoylphorbol-13-acetate-induced activation of the c-Jun NH2-terminal kinase pathway in human colon cancer cells. | ||||||||||
| Author: | Okumura, K|Shirasawa, S|Nishioka, M|Sasazuki, T | ||||||||||
| PMID: | 10344756 | ||||||||||
| 3. | |||||||||||
| Journal: | J Biol Chem. 2001 May 11;276(19):16406-10. Epub 2001 Mar 14. | ||||||||||
| Title: | Protein kinase G activates the JNK1 pathway via phosphorylation of MEKK1. | ||||||||||
| Author: | Soh, J W|Mao, Y|Liu, L|Thompson, W J|Pamukcu, R|Weinstein, I B | ||||||||||
| PMID: | 11278263 | ||||||||||
| 4. | |||||||||||
| Journal: | Oncogene. 2004 Oct 7;23(46):7712-21. | ||||||||||
| Title: | Luteolin sensitizes tumor necrosis factor-alpha-induced apoptosis in human tumor cells. | ||||||||||
| Author: | Shi, Ran-Xin|Ong, Choon-Nam|Shen, Han-Ming | ||||||||||
| PMID: | 15334063 | ||||||||||
| 5. | |||||||||||
| Journal: | Clin Cancer Res. 2006 Nov 1;12(21):6532-9. | ||||||||||
| Title: | 2-methoxyestradiol, an endogenous mammalian metabolite, radiosensitizes colon carcinoma cells through c-Jun NH2-terminal kinase activation. | ||||||||||
| Author: | Zou, HuiChao|Adachi, Masaaki|Imai, Kohzoh|Hareyama, Masato|Yoshioka, Katsuji|Zhao, Shiguang|Shinomura, Yasuhisa | ||||||||||
| PMID: | 17085668 | ||||||||||
| 6. | |||||||||||
| Journal: | Mol Pharmacol. 2008 Jul;74(1):246-54. | ||||||||||
| Title: | Disruption of signaling through SEK1 and MKK7 yields differential responses in hypoxic colon cancer cells treated with oxaliplatin. | ||||||||||
| Author: | Vasilevskaya, Irina A|Selvakumaran, Muthu|O'Dwyer, Peter J | ||||||||||
| PMID: | 18436711 | ||||||||||
| 7. | |||||||||||
| Journal: | Mol Cell Biochem. 2009 Aug;328(1-2):201-8. | ||||||||||
| Title: | MAP kinases in proliferating human colon cancer Caco-2 cells. | ||||||||||
| Author: | Buzzi, Natalia|Colicheo, Andrea|Boland, Ricardo|de Boland, Ana Russo | ||||||||||
| PMID: | 19301097 | ||||||||||
| 8. | |||||||||||
| Journal: | Int J Cancer. 2009 Oct 15;125(8):1876-83. | ||||||||||
| Title: | The association between -1304T>G polymorphism in the promoter of MKK4 gene and the risk of sporadic colorectal cancer in southern Chinese population. | ||||||||||
| Author: | Wei, Yisheng|Wang, Lei|Lan, Ping|Zhao, Hongjun|Pan, Zhizhong|Huang, Jun|Lu, Jiachun|Wang, Jianping | ||||||||||
| PMID: | 19610067 | ||||||||||
| 9. | |||||||||||
| Journal: | Int J Cancer. 2012 May 1;130(9):1981-90. | ||||||||||
| Title: | The protective role of polymorphism MKK4-1304 T>G in nasopharyngeal carcinoma is modulated by Epstein-Barr virus' infection status. | ||||||||||
| Author: | Zheng, Jian|Liu, Bin|Zhang, Liyuan|Jiang, Lan|Huang, Binfang|You, Yonghe|Jiang, Qingping|Zhang, Shuxu|Lu, Jiachun|Zhou, Yifeng | ||||||||||
| PMID: | 21702039 | ||||||||||
| 10. | |||||||||||
| Journal: | J Biol Chem. 2013 Jan 18;288(3):1883-95. | ||||||||||
| Title: | c-Jun N-terminal kinase 1 (JNK1) is required for coordination of netrin signaling in axon guidance. | ||||||||||
| Author: | Qu, Chao|Li, Weiquan|Shao, Qiangqiang|Dwyer, Trisha|Huang, Huai|Yang, Tao|Liu, Guofa | ||||||||||
| PMID: | 23223444 | ||||||||||
| 11. | |||||||||||
| Journal: | Zhonghua Yi Xue Za Zhi. 2013 Mar 12;93(10):746-50. | ||||||||||
| Title: | [Expression and clinicopathological significance of serine-257/threonine-261 phosphorylated MKK4 in colorectal carcinoma]. | ||||||||||
| Author: | Huang, Mei-jin|Wang, Pu-ning|Huang, Jun|Zhang, Xing-wei|Wang, Lei|Liu, Huan-liang|Wang, Jian-ping | ||||||||||
| PMID: | 23755811 | ||||||||||
| 12. | |||||||||||
| Journal: | Clin Cancer Res. 2014 Jan 1;20(1):265-72. | ||||||||||
| Title: | Modeling RAS phenotype in colorectal cancer uncovers novel molecular traits of RAS dependency and improves prediction of response to targeted agents in patients. | ||||||||||
| Author: | Guinney, Justin|Ferte, Charles|Dry, Jonathan|McEwen, Robert|Manceau, Gilles|Kao, K J|Chang, Kai-Ming|Bendtsen, Claus|Hudson, Kevin|Huang, Erich|Dougherty, Brian|Ducreux, Michel|Soria, Jean-Charles|Friend, Stephen|Derry, Jonathan|Laurent-Puig, Pierre | ||||||||||
| PMID: | 24170544 | ||||||||||
| 13. | |||||||||||
| Journal: | Anticancer Agents Med Chem. 2014;14(7):1051-61. | ||||||||||
| Title: | ent-kaurane diterpenoids from Croton tonkinensis induce apoptosis in colorectal cancer cells through the phosphorylation of JNK mediated by reactive oxygen species and dual-specificity JNK kinase MKK4. | ||||||||||
| Author: | Thuong, Phuong Thien|Khoi, Nguyen Minh|Ohta, Saho|Shiota, Shinichiro|Kanta, Hironori|Takeuchi, Kenji|Ito, Fumiaki | ||||||||||
| PMID: | 24476312 | ||||||||||
| 14. | |||||||||||
| Journal: | Neuro Endocrinol Lett. 2016 Jul;37(3):245-250. | ||||||||||
| Title: | Internalization property of intestinal bacteria in colon cancer and HIV/AIDS patients. | ||||||||||
| Author: | Wachsmannova, Lenka|Ciernikova, Sona|Majek, Juraj|Mego, Michal|Stevurkova, Viola|Zajac, Vladimir | ||||||||||
| PMID: | 27618600 | ||||||||||
| 15. | |||||||||||
| Journal: | Oncotarget. 2017 Jan 24;8(4):6579-6588. | ||||||||||
| Title: | Whole-exome sequencing identified mutational profiles of high-grade colon adenomas. | ||||||||||
| Author: | Lee, Sung Hak|Jung, Seung Hyun|Kim, Tae-Min|Rhee, Je-Keun|Park, Hyeon-Chun|Kim, Min Sung|Kim, Sung Soo|An, Chang Hyeok|Lee, Sug Hyung|Chung, Yeun-Jun | ||||||||||
| PMID: | 28179590 | ||||||||||
| 16. | |||||||||||
| Journal: | Oncotarget. 2017 May 23;8(21):34352-34361. | ||||||||||
| Title: | Downregulation of phosphorylated MKK4 is associated with a poor prognosis in colorectal cancer patients. | ||||||||||
| Author: | Wang, Pu-Ning|Huang, Jun|Duan, Ying-Hua|Zhou, Jia-Min|Huang, Pin-Zhu|Fan, Xin-Juan|Huang, Yan|Wang, Lei|Liu, Huan-Liang|Wang, Jian-Ping|Huang, Mei-Jin | ||||||||||
| PMID: | 28423721 | ||||||||||
| 17. | |||||||||||
| Journal: | Oncol Lett. 2017 Mar;13(3):1665-1671. | ||||||||||
| Title: | miR-141 promotes colon cancer cell proliferation by inhibiting MAP2K4. | ||||||||||
| Author: | Ding, Lei|Yu, Li-Li|Han, Ning|Zhang, Bu-Tian | ||||||||||
| PMID: | 28454307 | ||||||||||