Primary Site >> Pancreatic Cancer

Gene >> MAP1LC3A

Journal: Cancer Sci. 2008 Sep;99(9):1813-9.
Title: Autophagy is activated in pancreatic cancer cells and correlates with poor patient outcome.
Author: Fujii, Satoshi|Mitsunaga, Shuichi|Yamazaki, Manabu|Hasebe, Takahiro|Ishii, Genichiro|Kojima, Motohiro|Kinoshita, Taira|Ueno, Takashi|Esumi, Hiroyasu|Ochiai, Atsushi
PMID: 18616529
Journal: Br J Cancer. 2008 Jan 29;98(2):399-409.
Title: Antitumour effect of polyoxomolybdates: induction of apoptotic cell death and autophagy in in vitro and in vivo models.
Author: Ogata, A|Yanagie, H|Ishikawa, E|Morishita, Y|Mitsui, S|Yamashita, A|Hasumi, K|Takamoto, S|Yamase, T|Eriguchi, M
PMID: 18087283
Journal: J Surg Res. 2010 Oct;163(2):276-81.
Title: Targeting Bcl-2-mediated cell death as a novel therapy in pancreatic cancer.
Author: Muilenburg, Diego J|Coates, Jodi M|Virudachalam, Subbulakshmi|Bold, Richard J
PMID: 20452611
Journal: Int J Oncol. 2010 Oct;37(4):821-8.
Title: The role of autophagy in the treatment of pancreatic cancer with gemcitabine and ionizing radiation.
Author: Mukubou, Hideyo|Tsujimura, Toshiaki|Sasaki, Ryohei|Ku, Yonson
PMID: 20811703
Journal: Cancer Chemother Pharmacol. 2011 Aug;68(2):477-87.
Title: Cytotoxic responses to N-(4-hydroxyphenyl)retinamide in human pancreatic cancer cells.
Author: Messner, Maria C|Cabot, Myles C
PMID: 21072519
Journal: Int J Oncol. 2011 Jul;39(1):101-9.
Title: Autophagy and cell death signaling following dietary sulforaphane act independently of each other and require oxidative stress in pancreatic cancer.
Author: Naumann, Patrick|Fortunato, Franco|Zentgraf, Hanswalter|Buchler, Markus W|Herr, Ingrid|Werner, Jens
PMID: 21537844
Journal: PLoS One. 2011;6(5):e20143.
Title: Omeprazole inhibits proliferation and modulates autophagy in pancreatic cancer cells.
Author: Udelnow, Andrej|Kreyes, Andreas|Ellinger, Stefan|Landfester, Katharina|Walther, Paul|Klapperstueck, Thomas|Wohlrab, Johannes|Henne-Bruns, Doris|Knippschild, Uwe|Wurl, Peter
PMID: 21629657
Journal: J Pathol. 2012 Jul;227(3):325-35.
Title: Autophagy mediates survival of pancreatic tumour-initiating cells in a hypoxic microenvironment.
Author: Rausch, Vanessa|Liu, Li|Apel, Anja|Rettig, Theresa|Gladkich, Jury|Labsch, Sabrina|Kallifatidis, Georgios|Kaczorowski, Adam|Groth, Ariane|Gross, Wolfgang|Gebhard, Martha M|Schemmer, Peter|Werner, Jens|Salnikov, Alexei V|Zentgraf, Hanswalter|Buchler, Markus
PMID: 22262369
Journal: PLoS One. 2012;7(10):e47126.
Title: Autophagy creates a CTL epitope that mimics tumor-associated antigens.
Author: Demachi-Okamura, Ayako|Torikai, Hiroki|Akatsuka, Yoshiki|Miyoshi, Hiroyuki|Yoshimori, Tamotsu|Kuzushima, Kiyotaka
PMID: 23071732
Journal: Cancer Chemother Pharmacol. 2013 Mar;71(3):635-45.
Title: Potential role of acid ceramidase in conversion of cytostatic to cytotoxic end-point in pancreatic cancer cells.
Author: Morad, Samy A F|Messner, Maria C|Levin, Jonathan C|Abdelmageed, Noha|Park, Hyejung|Merrill, Alfred H Jr|Cabot, Myles C
PMID: 23263160
Journal: Cancer Cell Int. 2013 Mar 13;13(1):26.
Title: Beclin1 inhibition promotes autophagy and decreases gemcitabine-induced apoptosis in Miapaca2 pancreatic cancer cells.
Author: Li, Xiaoshu|Yan, Jun|Wang, Lisheng|Xiao, Fengjun|Yang, Yuefeng|Guo, Xiaozhong|Wang, Hua
PMID: 23497401
Journal: Mar Drugs. 2013 Sep 17;11(9):3500-16.
Title: The marine natural product manzamine A targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells.
Author: Kallifatidis, Georgios|Hoepfner, Dominic|Jaeg, Tiphaine|Guzman, Esther A|Wright, Amy E
PMID: 24048269
Journal: Cancer Gene Ther. 2013 Dec;20(12):663-70.
Title: Heat-shock protein 90 inhibitors synergistically enhance melanoma differentiation-associated gene-7-mediated cell killing of human pancreatic carcinoma.
Author: Zhang, Z|Kawamura, K|Jiang, Y|Shingyoji, M|Ma, G|Li, Q|Hu, J|Qi, Y|Liu, H|Zhang, F|Kang, S|Shan, B|Wang, S|Chada, S|Tagawa, M
PMID: 24263157
Journal: Oncol Lett. 2014 Sep;8(3):1087-1089.
Title: Shikonin promotes autophagy in BXPC-3 human pancreatic cancer cells through the PI3K/Akt signaling pathway.
Author: Shi, Shuqing|Cao, Haimei
PMID: 25120662
Journal: Oncol Rep. 2014 Dec;32(6):2726-34.
Title: Ubiquitinspecific protease 22induced autophagy is correlated with poor prognosis of pancreatic cancer.
Author: Liang, Jin-Xiao|Ning, Zhen|Gao, Wei|Ling, Jun|Wang, A-Man|Luo, Hai-Feng|Liang, Yong|Yan, Qiu|Wang, Zhong-Yu
PMID: 25241857
Journal: Oncotarget. 2014 May 15;5(9):2529-41.
Title: STAT3 down regulates LC3 to inhibit autophagy and pancreatic cancer cell growth.
Author: Gong, Jingjing|Munoz, Amanda R|Chan, Daniel|Ghosh, Rita|Kumar, Addanki P
PMID: 24796733
Journal: J Exp Clin Cancer Res. 2014 Jan 18;33:8.
Title: The activation of c-Jun NH(2)-terminal kinase is required for dihydroartemisinin-induced autophagy in pancreatic cancer cells.
Author: Jia, Guang|Kong, Rui|Ma, Zhi-Bin|Han, Bing|Wang, Yong-Wei|Pan, Shang-Ha|Li, Ying-Hua|Sun, Bei
PMID: 24438216
Journal: Hum Pathol. 2015 Feb;46(2):202-9.
Title: Autophagy may occur at an early stage of cholangiocarcinogenesis via biliary intraepithelial neoplasia.
Author: Sasaki, Motoko|Nitta, Takeo|Sato, Yasunori|Nakanuma, Yasuni
PMID: 25466963
Journal: Drug Des Devel Ther. 2015 Jan 17;9:537-60.
Title: Plumbagin induces cell cycle arrest and autophagy and suppresses epithelial to mesenchymal transition involving PI3K/Akt/mTOR-mediated pathway in human pancreatic cancer cells.
Author: Wang, Feng|Wang, Qi|Zhou, Zhi-Wei|Yu, Song-Ning|Pan, Shu-Ting|He, Zhi-Xu|Zhang, Xueji|Wang, Dong|Yang, Yin-Xue|Yang, Tianxing|Sun, Tao|Li, Min|Qiu, Jia-Xuan|Zhou, Shu-Feng
PMID: 25632222
Journal: PLoS One. 2015 Feb 26;10(2):e0115153.
Title: Metabolic phenotypes in pancreatic cancer.
Author: Yu, Min|Zhou, Quanbo|Zhou, Yu|Fu, Zhiqiang|Tan, Langping|Ye, Xiao|Zeng, Bing|Gao, Wenchao|Zhou, Jiajia|Liu, Yimin|Li, Zhihua|Lin, Ye|Lin, Qing|Chen, Rufu
PMID: 25719198
Journal: J Biomed Sci. 2015 Apr 17;22:28.
Title: Novel adjuvants from seaweed impede autophagy signaling in therapy-resistant residual pancreatic cancer.
Author: Aravindan, Sheeja|Ramraj, Satish Kumar|Somasundaram, Somasundaram T|Aravindan, Natarajan
PMID: 25898131
Journal: Mol Cancer. 2015 Oct 12;14:179.
Title: Blockade of autophagy reduces pancreatic cancer stem cell activity and potentiates the tumoricidal effect of gemcitabine.
Author: Yang, Ming-Chen|Wang, Hao-Chen|Hou, Ya-Chin|Tung, Hui-Ling|Chiu, Tai-Jan|Shan, Yan-Shen
PMID: 26458814
Journal: PLoS One. 2015 Nov 16;10(11):e0143150.
Title: Transforming Growth Factor TGFbeta Increases Levels of Microtubule-Associated Protein MAP1S and Autophagy Flux in Pancreatic Ductal Adenocarcinomas.
Author: Song, Kun|Hu, Wei|Yue, Fei|Zou, Jing|Li, Wenjiao|Chen, Qi|Yao, Qizhi|Sun, Weijia|Liu, Leyuan
PMID: 26571030
Journal: Oxid Med Cell Longev. 2016;2016:3897250.
Title: The Relevance of Nrf2 Pathway and Autophagy in Pancreatic Cancer Cells upon Stimulation of Reactive Oxygen Species.
Author: Zhang, Lun|Li, Jiahui|Ma, Jiguang|Chen, Xin|Chen, Ke|Jiang, Zhengdong|Zong, Liang|Yu, Shuo|Li, Xuqi|Xu, Qinhong|Lei, Jianjun|Duan, Wanxing|Li, Wei|Shan, Tao|Ma, Qingyong|Shen, Xin
PMID: 26682003
Journal: Oncogene. 2016 Nov 10;35(45):5882-5892.
Title: Hypoxia-induced oxidative stress promotes MUC4 degradation via autophagy to enhance pancreatic cancer cells survival.
Author: Joshi, S|Kumar, S|Ponnusamy, M P|Batra, S K
PMID: 27109098
Journal: Mol Cancer Ther. 2016 Sep;15(9):2232-43.
Title: Long Noncoding RNA MALAT1 Promotes Aggressive Pancreatic Cancer Proliferation and Metastasis via the Stimulation of Autophagy.
Author: Li, Le|Chen, Hua|Gao, Yue|Wang, Yong-Wei|Zhang, Guang-Quan|Pan, Shang-Ha|Ji, Liang|Kong, Rui|Wang, Gang|Jia, Yue-Hui|Bai, Xue-Wei|Sun, Bei
PMID: 27371730
Journal: Cancer Chemother Pharmacol. 2016 Dec;78(6):1199-1207.
Title: Linc-ROR confers gemcitabine resistance to pancreatic cancer cells via inducing autophagy and modulating the miR-124/PTBP1/PKM2 axis.
Author: Li, Chenggang|Zhao, Zhiming|Zhou, Zhipeng|Liu, Rong
PMID: 27785603
Journal: Pancreas. 2017 Apr;46(4):575-581.
Title: Autophagy Induced by CX-4945, a Casein Kinase 2 Inhibitor, Enhances Apoptosis in Pancreatic Cancer Cell Lines.
Author: Hwang, Dae Wook|So, Kwang Sup|Kim, Song Cheol|Park, Kwang-Min|Lee, Young-Joo|Kim, Sun-Whe|Choi, Chang-Min|Rho, Jin Kyung|Choi, Yun Jung|Lee, Jae Cheol
PMID: 28196025
Journal: Oxid Med Cell Longev. 2017;2017:7085709.
Title: Picroside II Shows Protective Functions for Severe Acute Pancreatitis in Rats by Preventing NF-kappaB-Dependent Autophagy.
Author: Piao, Xuehua|Liu, Baohai|Guo, Lianyi|Meng, Fanji|Gao, Leming
PMID: 28713490
Journal: World J Gastroenterol. 2017 Oct 28;23(40):7232-7241.
Title: Relationship between autophagy and perineural invasion, clinicopathological features, and prognosis in pancreatic cancer.
Author: Yang, Yan-Hui|Liu, Jiang-Bo|Gui, Yang|Lei, Liang-Liang|Zhang, Shui-Jun
PMID: 29142470
Journal: J Nat Prod. 2018 Oct 26;81(10):2282-2291.
Title: Ancistrolikokine E3, a 5,8'-Coupled Naphthylisoquinoline Alkaloid, Eliminates the Tolerance of Cancer Cells to Nutrition Starvation by Inhibition of the Akt/mTOR/Autophagy Signaling Pathway.
Author: Awale, Suresh|Dibwe, Dya Fita|Balachandran, Chandrasekar|Fayez, Shaimaa|Feineis, Doris|Lombe, Blaise Kimbadi|Bringmann, Gerhard
PMID: 30303002