Primary Site >> Pancreatic Cancer

Gene >> MAP1LC3A

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Ref: Antitumour effect of polyoxomolybdates: induction of apoptotic cell death and autophagy in in vitro and in vivo models.
PMID: 18087283
Ref: Autophagy is activated in pancreatic cancer cells and correlates with poor patient outcome.
PMID: 18616529
Ref: Targeting Bcl-2-mediated cell death as a novel therapy in pancreatic cancer.
PMID: 20452611
Ref: The role of autophagy in the treatment of pancreatic cancer with gemcitabine and ionizing radiation.
PMID: 20811703
Ref: Cytotoxic responses to N-(4-hydroxyphenyl)retinamide in human pancreatic cancer cells.
PMID: 21072519
Ref: Autophagy and cell death signaling following dietary sulforaphane act independently of each other and require oxidative stress in pancreatic cancer.
PMID: 21537844
Ref: Omeprazole inhibits proliferation and modulates autophagy in pancreatic cancer cells.
PMID: 21629657
Ref: Autophagy mediates survival of pancreatic tumour-initiating cells in a hypoxic microenvironment.
PMID: 22262369
Ref: Autophagy creates a CTL epitope that mimics tumor-associated antigens.
PMID: 23071732
Ref: Potential role of acid ceramidase in conversion of cytostatic to cytotoxic end-point in pancreatic cancer cells.
PMID: 23263160
Ref: Beclin1 inhibition promotes autophagy and decreases gemcitabine-induced apoptosis in Miapaca2 pancreatic cancer cells.
PMID: 23497401
Ref: The marine natural product manzamine A targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells.
PMID: 24048269
Ref: Heat-shock protein 90 inhibitors synergistically enhance melanoma differentiation-associated gene-7-mediated cell killing of human pancreatic carcinoma.
PMID: 24263157
Ref: The activation of c-Jun NH(2)-terminal kinase is required for dihydroartemisinin-induced autophagy in pancreatic cancer cells.
PMID: 24438216
Ref: STAT3 down regulates LC3 to inhibit autophagy and pancreatic cancer cell growth.
PMID: 24796733
Ref: Shikonin promotes autophagy in BXPC-3 human pancreatic cancer cells through the PI3K/Akt signaling pathway.
PMID: 25120662
Ref: Ubiquitinspecific protease 22induced autophagy is correlated with poor prognosis of pancreatic cancer.
PMID: 25241857
Ref: Autophagy may occur at an early stage of cholangiocarcinogenesis via biliary intraepithelial neoplasia.
PMID: 25466963
Ref: Plumbagin induces cell cycle arrest and autophagy and suppresses epithelial to mesenchymal transition involving PI3K/Akt/mTOR-mediated pathway in human pancreatic cancer cells.
PMID: 25632222
Ref: Metabolic phenotypes in pancreatic cancer.
PMID: 25719198
Ref: Novel adjuvants from seaweed impede autophagy signaling in therapy-resistant residual pancreatic cancer.
PMID: 25898131
Ref: Blockade of autophagy reduces pancreatic cancer stem cell activity and potentiates the tumoricidal effect of gemcitabine.
PMID: 26458814
Ref: Transforming Growth Factor TGFbeta Increases Levels of Microtubule-Associated Protein MAP1S and Autophagy Flux in Pancreatic Ductal Adenocarcinomas.
PMID: 26571030
Ref: The Relevance of Nrf2 Pathway and Autophagy in Pancreatic Cancer Cells upon Stimulation of Reactive Oxygen Species.
PMID: 26682003
Ref: Hypoxia-induced oxidative stress promotes MUC4 degradation via autophagy to enhance pancreatic cancer cells survival.
PMID: 27109098
Ref: Long Noncoding RNA MALAT1 Promotes Aggressive Pancreatic Cancer Proliferation and Metastasis via the Stimulation of Autophagy.
PMID: 27371730
Ref: Linc-ROR confers gemcitabine resistance to pancreatic cancer cells via inducing autophagy and modulating the miR-124/PTBP1/PKM2 axis.
PMID: 27785603
Ref: Autophagy Induced by CX-4945, a Casein Kinase 2 Inhibitor, Enhances Apoptosis in Pancreatic Cancer Cell Lines.
PMID: 28196025
Ref: Picroside II Shows Protective Functions for Severe Acute Pancreatitis in Rats by Preventing NF-kappaB-Dependent Autophagy.
PMID: 28713490
Ref: Relationship between autophagy and perineural invasion, clinicopathological features, and prognosis in pancreatic cancer.
PMID: 29142470
Ref: Ancistrolikokine E3, a 5,8'-Coupled Naphthylisoquinoline Alkaloid, Eliminates the Tolerance of Cancer Cells to Nutrition Starvation by Inhibition of the Akt/mTOR/Autophagy Signaling Pathway.
PMID: 30303002