Primary Site >> Pancreatic Cancer
Gene >> MAP1LC3A
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Ref: Antitumour effect of polyoxomolybdates: induction of apoptotic cell death and autophagy in in vitro and in vivo models. PMID: 18087283 Ref: Autophagy is activated in pancreatic cancer cells and correlates with poor patient outcome. PMID: 18616529 |
Ref: Targeting Bcl-2-mediated cell death as a novel therapy in pancreatic cancer. PMID: 20452611 Ref: The role of autophagy in the treatment of pancreatic cancer with gemcitabine and ionizing radiation. PMID: 20811703 |
Ref: Cytotoxic responses to N-(4-hydroxyphenyl)retinamide in human pancreatic cancer cells. PMID: 21072519 Ref: Autophagy and cell death signaling following dietary sulforaphane act independently of each other and require oxidative stress in pancreatic cancer. PMID: 21537844 Ref: Omeprazole inhibits proliferation and modulates autophagy in pancreatic cancer cells. PMID: 21629657 |
Ref: Autophagy mediates survival of pancreatic tumour-initiating cells in a hypoxic microenvironment. PMID: 22262369 Ref: Autophagy creates a CTL epitope that mimics tumor-associated antigens. PMID: 23071732 |
Ref: Potential role of acid ceramidase in conversion of cytostatic to cytotoxic end-point in pancreatic cancer cells. PMID: 23263160 Ref: Beclin1 inhibition promotes autophagy and decreases gemcitabine-induced apoptosis in Miapaca2 pancreatic cancer cells. PMID: 23497401 Ref: The marine natural product manzamine A targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells. PMID: 24048269 Ref: Heat-shock protein 90 inhibitors synergistically enhance melanoma differentiation-associated gene-7-mediated cell killing of human pancreatic carcinoma. PMID: 24263157 |
Ref: The activation of c-Jun NH(2)-terminal kinase is required for dihydroartemisinin-induced autophagy in pancreatic cancer cells. PMID: 24438216 Ref: STAT3 down regulates LC3 to inhibit autophagy and pancreatic cancer cell growth. PMID: 24796733 Ref: Shikonin promotes autophagy in BXPC-3 human pancreatic cancer cells through the PI3K/Akt signaling pathway. PMID: 25120662 Ref: Ubiquitinspecific protease 22induced autophagy is correlated with poor prognosis of pancreatic cancer. PMID: 25241857 |
Ref: Autophagy may occur at an early stage of cholangiocarcinogenesis via biliary intraepithelial neoplasia. PMID: 25466963 Ref: Plumbagin induces cell cycle arrest and autophagy and suppresses epithelial to mesenchymal transition involving PI3K/Akt/mTOR-mediated pathway in human pancreatic cancer cells. PMID: 25632222 Ref: Metabolic phenotypes in pancreatic cancer. PMID: 25719198 Ref: Novel adjuvants from seaweed impede autophagy signaling in therapy-resistant residual pancreatic cancer. PMID: 25898131 Ref: Blockade of autophagy reduces pancreatic cancer stem cell activity and potentiates the tumoricidal effect of gemcitabine. PMID: 26458814 Ref: Transforming Growth Factor TGFbeta Increases Levels of Microtubule-Associated Protein MAP1S and Autophagy Flux in Pancreatic Ductal Adenocarcinomas. PMID: 26571030 |
Ref: The Relevance of Nrf2 Pathway and Autophagy in Pancreatic Cancer Cells upon Stimulation of Reactive Oxygen Species. PMID: 26682003 Ref: Hypoxia-induced oxidative stress promotes MUC4 degradation via autophagy to enhance pancreatic cancer cells survival. PMID: 27109098 Ref: Long Noncoding RNA MALAT1 Promotes Aggressive Pancreatic Cancer Proliferation and Metastasis via the Stimulation of Autophagy. PMID: 27371730 Ref: Linc-ROR confers gemcitabine resistance to pancreatic cancer cells via inducing autophagy and modulating the miR-124/PTBP1/PKM2 axis. PMID: 27785603 |
Ref: Autophagy Induced by CX-4945, a Casein Kinase 2 Inhibitor, Enhances Apoptosis in Pancreatic Cancer Cell Lines. PMID: 28196025 Ref: Picroside II Shows Protective Functions for Severe Acute Pancreatitis in Rats by Preventing NF-kappaB-Dependent Autophagy. PMID: 28713490 Ref: Relationship between autophagy and perineural invasion, clinicopathological features, and prognosis in pancreatic cancer. PMID: 29142470 |
Ref: Ancistrolikokine E3, a 5,8'-Coupled Naphthylisoquinoline Alkaloid, Eliminates the Tolerance of Cancer Cells to Nutrition Starvation by Inhibition of the Akt/mTOR/Autophagy Signaling Pathway. PMID: 30303002 |