Literatures

Primary Site >> Colorectal Cancer

Gene >> MAP1LC3A

1.
Journal:	Clin Cancer Res. 2007 Feb 15;13(4):1315-21.
Title:	DNA mismatch repair initiates 6-thioguanine--induced autophagy through p53 activation in human tumor cells.
Author:	Zeng, Xuehuo\|Yan, Tao\|Schupp, Jane E\|Seo, Yuji\|Kinsella, Timothy J
PMID:	17317843

2.
Journal:	Cancer Res. 2007 Oct 15;67(20):9677-84.
Title:	Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation.
Author:	Sato, Kazunori\|Tsuchihara, Katsuya\|Fujii, Satoshi\|Sugiyama, Masanori\|Goya, Tomoyuki\|Atomi, Yutaka\|Ueno, Takashi\|Ochiai, Atsushi\|Esumi, Hiroyasu
PMID:	17942897

3.
Journal:	Cancer Res. 2008 Apr 1;68(7):2384-90.
Title:	Mammalian target of rapamycin and S6 kinase 1 positively regulate 6-thioguanine-induced autophagy.
Author:	Zeng, Xuehuo\|Kinsella, Timothy J
PMID:	18381446

4.
Journal:	Cancer Sci. 2008 Sep;99(9):1813-9.
Title:	Autophagy is activated in pancreatic cancer cells and correlates with poor patient outcome.
Author:	Fujii, Satoshi\|Mitsunaga, Shuichi\|Yamazaki, Manabu\|Hasebe, Takahiro\|Ishii, Genichiro\|Kojima, Motohiro\|Kinoshita, Taira\|Ueno, Takashi\|Esumi, Hiroyasu\|Ochiai, Atsushi
PMID:	18616529

5.
Journal:	Biochem Biophys Res Commun. 2008 Sep 19;374(2):258-63.
Title:	Induction of autophagy by proteasome inhibitor is associated with proliferative arrest in colon cancer cells.
Author:	Wu, William Ka Kei\|Wu, Ya Chun\|Yu, Le\|Li, Zhi Jie\|Sung, Joseph Jao Yiu\|Cho, Chi Hin
PMID:	18638451

6.
Journal:	Int J Oncol. 2008 Sep;33(3):461-8.
Title:	LC3, an autophagosome marker, is highly expressed in gastrointestinal cancers.
Author:	Yoshioka, Akiko\|Miyata, Hiroshi\|Doki, Yuichiro\|Yamasaki, Makoto\|Sohma, Itsuro\|Gotoh, Kunihito\|Takiguchi, Shuji\|Fujiwara, Yoshiyuki\|Uchiyama, Yasuo\|Monden, Morito
PMID:	18695874

7.
Journal:	Biochem Biophys Res Commun. 2009 Apr 24;382(1):79-84.
Title:	Inhibition of cyclooxygenase-1 lowers proliferation and induces macroautophagy in colon cancer cells.
Author:	Wu, William Ka Kei\|Sung, Joseph Jao Yiu\|Wu, Ya Chun\|Li, Hai To\|Yu, Le\|Li, Zhi Jie\|Cho, Chi Hin
PMID:	19258012

8.
Journal:	Biochem Biophys Res Commun. 2009 May 1;382(2):451-6.
Title:	Inhibition of macroautophagy by bafilomycin A1 lowers proliferation and induces apoptosis in colon cancer cells.
Author:	Wu, Ya Chun\|Wu, William Ka Kei\|Li, Youming\|Yu, Le\|Li, Zhi Jie\|Wong, Clover Ching Man\|Li, Hai Tao\|Sung, Joseph Jao Yiu\|Cho, Chi Hin
PMID:	19289106

9.
Journal:	J Toxicol. 2009;2009:785907.
Title:	Deoxycholate, an endogenous cytotoxin/genotoxin, induces the autophagic stress-survival pathway: implications for colon carcinogenesis.
Author:	Payne, Claire M\|Crowley-Skillicorn, Cheray\|Holubec, Hana\|Dvorak, Katerina\|Bernstein, Carol\|Moyer, Mary Pat\|Garewal, Harinder\|Bernstein, Harris
PMID:	20130808

10.
Journal:	Cancer Lett. 2010 Feb 1;288(1):68-74.
Title:	Autophagic cell death induced by 5-FU in Bax or PUMA deficient human colon cancer cell.
Author:	Xiong, Hai-yan\|Guo, Xian-ling\|Bu, Xin-xin\|Zhang, Shan-shan\|Ma, Nan-nan\|Song, Jian-rui\|Hu, Fei\|Tao, Shuang-fen\|Sun, Kai\|Li, Rong\|Wu, Meng-chao\|Wei, Li-xin
PMID:	19660860

11.
Journal:	Ann Surg Oncol. 2010 Feb;17(2):592-602.
Title:	Inhibition of autophagy potentiates sulforaphane-induced apoptosis in human colon cancer cells.
Author:	Nishikawa, Takeshi\|Tsuno, Nelson H\|Okaji, Yurai\|Shuno, Yasutaka\|Sasaki, Kazuhito\|Hongo, Kumiko\|Sunami, Eiji\|Kitayama, Joji\|Takahashi, Koki\|Nagawa, Hirokazu
PMID:	19830499

12.
Journal:	Autophagy. 2010 Feb;6(2):256-69. Epub 2010 Feb 6.
Title:	Celecoxib-induced apoptosis is enhanced by ABT-737 and by inhibition of autophagy in human colorectal cancer cells.
Author:	Huang, Shengbing\|Sinicrope, Frank A
PMID:	20104024

13.
Journal:	Am J Pathol. 2010 May;176(5):2477-89.
Title:	LC3A-positive light microscopy detected patterns of autophagy and prognosis in operable breast carcinomas.
Author:	Sivridis, Efthimios\|Koukourakis, Michael I\|Zois, Christos E\|Ledaki, Ioanna\|Ferguson, David J P\|Harris, Adrian L\|Gatter, Kevin C\|Giatromanolaki, Alexandra
PMID:	20382705

14.
Journal:	Nat Cell Biol. 2010 Aug;12(8):781-90.
Title:	Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation.
Author:	Gao, Chan\|Cao, Weipeng\|Bao, Lan\|Zuo, Wei\|Xie, Guoming\|Cai, Tiantian\|Fu, Wei\|Zhang, Jian\|Wu, Wei\|Zhang, Xu\|Chen, Ye-Guang
PMID:	20639871

15.
Journal:	Angiogenesis. 2010 Sep;13(3):227-38.
Title:	The inhibition of autophagy potentiates anti-angiogenic effects of sulforaphane by inducing apoptosis.
Author:	Nishikawa, Takeshi\|Tsuno, Nelson H\|Okaji, Yurai\|Sunami, Eiji\|Shuno, Yasutaka\|Sasaki, Kazuhito\|Hongo, Kumiko\|Kaneko, Manabu\|Hiyoshi, Masaya\|Kawai, Kazushige\|Kitayama, Joji\|Takahashi, Koki\|Nagawa, Hirokazu
PMID:	20694744

16.
Journal:	Autophagy. 2010 Oct;6(7):863-70.
Title:	UVRAG mutations associated with microsatellite unstable colon cancer do not affect autophagy.
Author:	Knaevelsrud, Helene\|Ahlquist, Terje\|Merok, Marianne A\|Nesbakken, Arild\|Stenmark, Harald\|Lothe, Ragnhild A\|Simonsen, Anne
PMID:	20724836

17.
Journal:	Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18511-6.
Title:	p53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation.
Author:	Scherz-Shouval, Ruth\|Weidberg, Hilla\|Gonen, Chagay\|Wilder, Sylvia\|Elazar, Zvulun\|Oren, Moshe
PMID:	20937856

18.
Journal:	Korean J Physiol Pharmacol. 2011 Feb;15(1):1-7.
Title:	Involvement of ROS in Curcumin-induced Autophagic Cell Death.
Author:	Lee, Youn Ju\|Kim, Nam-Yi\|Suh, Young-Ah\|Lee, Chuhee
PMID:	21461234

19.
Journal:	Int J Oncol. 2011 Jul;39(1):33-40.
Title:	Sesamin induces autophagy in colon cancer cells by reducing tyrosine phosphorylation of EphA1 and EphB2.
Author:	Tanabe, Hiromi\|Kuribayashi, Kageaki\|Tsuji, Naoki\|Tanaka, Maki\|Kobayashi, Daisuke\|Watanabe, Naoki
PMID:	21503576

20.
Journal:	World J Gastroenterol. 2011 Nov 21;17(43):4779-86.
Title:	Autophagy-related proteins Beclin-1 and LC3 predict cetuximab efficacy in advanced colorectal cancer.
Author:	Guo, Gui-Fang\|Jiang, Wen-Qi\|Zhang, Bei\|Cai, Yu-Chen\|Xu, Rui-Hua\|Chen, Xu-Xian\|Wang, Fang\|Xia, Liang-Ping
PMID:	22147978

21.
Journal:	Gastroenterology. 2012 Jun;142(7):1504-15.e3.
Title:	Aspirin inhibits mTOR signaling, activates AMP-activated protein kinase, and induces autophagy in colorectal cancer cells.
Author:	Din, Farhat V N\|Valanciute, Asta\|Houde, Vanessa P\|Zibrova, Daria\|Green, Kevin A\|Sakamoto, Kei\|Alessi, Dario R\|Dunlop, Malcolm G
PMID:	22406476

22.
Journal:	Mech Ageing Dev. 2012 Jun;133(6):444-55.
Title:	Curcumin induces permanent growth arrest of human colon cancer cells: link between senescence and autophagy.
Author:	Mosieniak, Grazyna\|Adamowicz, Marek\|Alster, Olga\|Jaskowiak, Hubert\|Szczepankiewicz, Andrzej A\|Wilczynski, Grzegorz M\|Ciechomska, Iwona A\|Sikora, Ewa
PMID:	22613224

23.
Journal:	PLoS One. 2012;7(9):e44132.
Title:	Salinomycin induces autophagy in colon and breast cancer cells with concomitant generation of reactive oxygen species.
Author:	Verdoodt, Berlinda\|Vogt, Markus\|Schmitz, Inge\|Liffers, Sven-Thorsten\|Tannapfel, Andrea\|Mirmohammadsadegh, Alireza
PMID:	23028492

24.
Journal:	Immune Netw. 2012 Dec;12(6):253-60.
Title:	alpha-Mangostin Reduced ER Stress-mediated Tumor Growth through Autophagy Activation.
Author:	Kim, Sung-Jin\|Hong, Eun-Hye\|Lee, Bo-Ra\|Park, Moon-Ho\|Kim, Ji-Won\|Pyun, A-Rim\|Kim, Yeon-Jeong\|Chang, Sun-Young\|Chin, Young-Won\|Ko, Hyun-Jeong
PMID:	23396851

25.
Journal:	J Nutr Biochem. 2013 Apr;24(4):706-12.
Title:	Ursolic acid induces cell death and modulates autophagy through JNK pathway in apoptosis-resistant colorectal cancer cells.
Author:	Xavier, Cristina P R\|Lima, Cristovao F\|Pedro, Dalila F N\|Wilson, Jonathan M\|Kristiansen, Karsten\|Pereira-Wilson, Cristina
PMID:	22841540

26.
Journal:	Cancer Chemother Pharmacol. 2013 Feb;71(2):441-55.
Title:	Autophagy, cell death and sustained senescence arrest in B16/F10 melanoma cells and HCT-116 colon carcinoma cells in response to the novel microtubule poison, JG-03-14.
Author:	Biggers, Jonathan W\|Nguyen, Tuyen\|Di, Xu\|Gupton, John T\|Henderson, Scott C\|Emery, Sean M\|Alotaibi, Moureq\|White, Kimber L Jr\|Brown, Ronetta\|Almenara, Jorge\|Gewirtz, David A
PMID:	23178952

27.
Journal:	Cancer Biol Ther. 2013 Feb;14(2):100-7.
Title:	Prognostic impact of Beclin 1, p62/sequestosome 1 and LC3 protein expression in colon carcinomas from patients receiving 5-fluorouracil as adjuvant chemotherapy.
Author:	Park, Jae Myung\|Huang, Shengbing\|Wu, Tsung-Teh\|Foster, Nathan R\|Sinicrope, Frank A
PMID:	23192274

28.
Journal:	PLoS One. 2013;8(1):e53664.
Title:	bis-Dehydroxy-Curcumin triggers mitochondrial-associated cell death in human colon cancer cells through ER-stress induced autophagy.
Author:	Basile, Valentina\|Belluti, Silvia\|Ferrari, Erika\|Gozzoli, Chiara\|Ganassi, Sonia\|Quaglino, Daniela\|Saladini, Monica\|Imbriano, Carol
PMID:	23326480

29.
Journal:	Biochem Biophys Res Commun. 2013 May 17;434(4):898-903.
Title:	Autophagy of cancer stem cells is involved with chemoresistance of colon cancer cells.
Author:	Wu, Shaobin\|Wang, Xianwei\|Chen, Jinxiang\|Chen, Yuxiang
PMID:	23624503

30.
Journal:	Zhonghua Yi Xue Za Zhi. 2013 Feb 26;93(8):614-8.
Title:	[Effects of autophagy modulator on autophagy and uridine 5'-diphospho-glucuronosyltransferase 1A1 induced by sulforaphane].
Author:	Wang, Min\|Chen, Shuo\|Qing, Ying\|Wu, Dong\|Lin, Ying-min\|Chen, Jian\|Li, Yan-qing
PMID:	23663345

31.
Journal:	PLoS One. 2013 May 20;8(5):e63641.
Title:	FK-16 derived from the anticancer peptide LL-37 induces caspase-independent apoptosis and autophagic cell death in colon cancer cells.
Author:	Ren, Shun X\|Shen, Jin\|Cheng, Alfred S L\|Lu, Lan\|Chan, Ruby L Y\|Li, Zhi J\|Wang, Xiao J\|Wong, Clover C M\|Zhang, Lin\|Ng, Simon S M\|Chan, Franky L\|Chan, Francis K L\|Yu, Jun\|Sung, Joseph J Y\|Wu, William K K\|Cho, Chi H
PMID:	23700428

32.
Journal:	Oncol Lett. 2013 May;5(5):1554-1558.
Title:	13,14-bis(cis-3,5-dimethyl-1-piperazinyl)-beta-elemene, a novel beta-elemene derivative, shows potent antitumor activities via inhibition of mTOR in human breast cancer cells.
Author:	Ding, Xiao-Fei\|Shen, Mao\|Xu, Li-Ying\|Dong, Jin-Hua\|Chen, Guang
PMID:	23761818

33.
Journal:	Dig Dis Sci. 2013 Oct;58(10):2887-94.
Title:	Downregulation of Beclin 1 and impairment of autophagy in a small population of colorectal cancer.
Author:	Chen, Zhihong\|Li, Yanchun\|Zhang, Chi\|Yi, Hongmei\|Wu, Chang\|Wang, Junpu\|Liu, Yuwu\|Tan, Jieqiong\|Wen, Jifang
PMID:	23812859

34.
Journal:	Pharm Res. 2013 Sep;30(9):2279-89.
Title:	Role of intracellular calcium in proteasome inhibitor-induced endoplasmic reticulum stress, autophagy, and cell death.
Author:	Williams, Jessica A\|Hou, Yifeng\|Ni, Hong-Min\|Ding, Wen-Xing
PMID:	23893020

35.
Journal:	Autophagy. 2013 Dec;9(12):2126-39.
Title:	BIX-01294 induces autophagy-associated cell death via EHMT2/G9a dysfunction and intracellular reactive oxygen species production.
Author:	Kim, Yunha\|Kim, Yong-Sook\|Kim, Dong Eun\|Lee, Jee Suk\|Song, Ji Hoon\|Kim, Ha-Gyeong\|Cho, Dong-Hyung\|Jeong, Seong-Yun\|Jin, Dong-Hoon\|Jang, Se Jin\|Seol, Hyang-Sook\|Suh, Young-Ah\|Lee, Seung Jin\|Kim, Choung-Soo\|Koh, Jae-Young\|Hwang, Jung Jin
PMID:	24322755

36.
Journal:	Mol Cell Biochem. 2014 Jan;385(1-2):95-102.
Title:	Knockdown of p62/sequestosome 1 attenuates autophagy and inhibits colorectal cancer cell growth.
Author:	Ren, Feng\|Shu, Guoshun\|Liu, Ganglei\|Liu, Dongcai\|Zhou, Jiapeng\|Yuan, Lianwen\|Zhou, Jianping
PMID:	24065390

37.
Journal:	Mol Cancer. 2014 Mar 2;13:43.
Title:	Cathepsin S-mediated autophagic flux in tumor-associated macrophages accelerate tumor development by promoting M2 polarization.
Author:	Yang, Min\|Liu, Jingwei\|Shao, Jianghua\|Qin, Yanwen\|Ji, Qunsheng\|Zhang, Xiaolin\|Du, Jie
PMID:	24580730

38.
Journal:	PLoS One. 2014 Feb 26;9(2):e90151.
Title:	Ambra1 is an essential regulator of autophagy and apoptosis in SW620 cells: pro-survival role of Ambra1.
Author:	Gu, Wen\|Wan, Daiwei\|Qian, Qinyi\|Yi, Bin\|He, Zhilong\|Gu, Yilin\|Wang, Liang\|He, Songbing
PMID:	24587252

39.
Journal:	Int J Oncol. 2014 May;44(5):1599-606.
Title:	Apigenin-induced apoptosis is enhanced by inhibition of autophagy formation in HCT116 human colon cancer cells.
Author:	Lee, Yujin\|Sung, Bokyung\|Kang, Yong Jung\|Kim, Dong Hwan\|Jang, Jung-Yoon\|Hwang, Seong Yeon\|Kim, Minjung\|Lim, Hyun Sook\|Yoon, Jeong-Hyun\|Chung, Hae Young\|Kim, Nam Deuk
PMID:	24626522

40.
Journal:	World J Gastrointest Oncol. 2014 Mar 15;6(3):74-82.
Title:	Autophagy inhibition by chloroquine sensitizes HT-29 colorectal cancer cells to concurrent chemoradiation.
Author:	Schonewolf, Caitlin A\|Mehta, Monal\|Schiff, Devora\|Wu, Hao\|Haffty, Bruce G\|Karantza, Vassiliki\|Jabbour, Salma K
PMID:	24653797

41.
Journal:	Apoptosis. 2014 Jun;19(6):1029-42.
Title:	WIN induces apoptotic cell death in human colon cancer cells through a block of autophagic flux dependent on PPARgamma down-regulation.
Author:	Pellerito, Ornella\|Notaro, Antonietta\|Sabella, Selenia\|De Blasio, Anna\|Vento, Renza\|Calvaruso, Giuseppe\|Giuliano, Michela
PMID:	24696378

42.
Journal:	Autophagy. 2014 Sep;10(9):1495-508.
Title:	Silencing of EEF2K (eukaryotic elongation factor-2 kinase) reveals AMPK-ULK1-dependent autophagy in colon cancer cells.
Author:	Xie, Chuan-Ming\|Liu, Xiao-Yu\|Sham, Kathy W Y\|Lai, Josie M Y\|Cheng, Christopher H K
PMID:	24955726

43.
Journal:	Anticancer Res. 2014 Sep;34(9):4709-16.
Title:	Effect of light irradiation by light emitting diode on colon cancer cells.
Author:	Matsumoto, Noriko\|Yoshikawa, Kozo\|Shimada, Mitsuo\|Kurita, Nobuhiro\|Sato, Hirohiko\|Iwata, Takashi\|Higashijima, Jun\|Chikakiyo, Motoya\|Nishi, Masaaki\|Kashihara, Hideya\|Takasu, Chie\|Eto, Shohei\|Takahashi, Akira\|Akutagawa, Masatake\|Emoto, Takahiro
PMID:	25202048

44.
Journal:	Oncol Lett. 2014 Dec;8(6):2581-2586.
Title:	Smac/DIABLO expression in human gastrointestinal carcinoma: Association with clinicopathological parameters and survivin expression.
Author:	Shintani, Michiko\|Sangawa, Akiko\|Yamao, Naoki\|Kamoshida, Shingo
PMID:	25364431

45.
Journal:	J Cell Physiol. 2015 Apr;230(4):930-46.
Title:	Justicidin A-induced autophagy flux enhances apoptosis of human colorectal cancer cells via class III PI3K and Atg5 pathway.
Author:	Won, Shen-Jeu\|Yen, Cheng-Hsin\|Liu, Hsiao-Sheng\|Wu, Shan-Ying\|Lan, Sheng-Hui\|Jiang-Shieh, Ya-Fen\|Lin, Chun-Nan\|Su, Chun-Li
PMID:	25216025

46.
Journal:	Oncology. 2015;88(1):28-48.
Title:	N3-substituted temozolomide analogs overcome methylguanine-DNA methyltransferase and mismatch repair precipitating apoptotic and autophagic cancer cell death.
Author:	Zhang, Jihong\|Hummersone, Marc\|Matthews, Charles S\|Stevens, Malcolm F G\|Bradshaw, Tracey D
PMID:	25277441

47.
Journal:	Biomaterials. 2015 Feb;40:12-22.
Title:	Graphene oxide as a chemosensitizer: diverted autophagic flux, enhanced nuclear import, elevated necrosis and improved antitumor effects.
Author:	Chen, Guan-Yu\|Meng, Chia-Le\|Lin, Kuan-Chen\|Tuan, Hsing-Yu\|Yang, Hong-Jie\|Chen, Chiu-Ling\|Li, Kuei-Chang\|Chiang, Chi-Shiun\|Hu, Yu-Chen
PMID:	25498801

48.
Journal:	Oncol Lett. 2015 Mar;9(3):1425-1431.
Title:	Involvement of autophagy inhibition in Brucea javanica oil emulsion-induced colon cancer cell death.
Author:	Yan, Zheng\|Zhang, Bei\|Huang, Yuanyuan\|Qiu, Huijuan\|Chen, Ping\|Guo, Gui-Fang
PMID:	25663926

49.
Journal:	Acta Pharmacol Sin. 2015 Apr;36(4):517-27.
Title:	Physalin B not only inhibits the ubiquitin-proteasome pathway but also induces incomplete autophagic response in human colon cancer cells in vitro.
Author:	Ma, Yi-ming\|Han, Wei\|Li, Jia\|Hu, Li-hong\|Zhou, Yu-bo
PMID:	25832431

50.
Journal:	Oncol Rep. 2015 Jun;33(6):2761-70.
Title:	Purvalanol induces endoplasmic reticulum stress-mediated apoptosis and autophagy in a time-dependent manner in HCT116 colon cancer cells.
Author:	Coker-Gurkan, Ajda\|Arisan, Elif Damla\|Obakan, Pinar\|Akalin, Kubra\|Ozbey, Utku\|Palavan-Unsal, Narcin
PMID:	25901510

51.
Journal:	Am J Cancer Res. 2015 Jan 15;5(2):498-513. eCollection 2015.
Title:	ART1 promotes starvation-induced autophagy: a possible protective role in the development of colon carcinoma.
Author:	Tang, Yi\|Li, Ming\|Wang, Ya-Lan\|Threadgill, Michael D\|Xiao, Ming\|Mou, Chun-Feng\|Song, Guang-Lin\|Kuang, Jing\|Yang, Xi\|Yang, Li\|Gao, Xing-Jie\|Wang, Ya-Ping\|Meng, Yun-Peng
PMID:	25973293

52.
Journal:	Int J Clin Exp Pathol. 2015 Apr 1;8(4):3882-91. eCollection 2015.
Title:	Expression and clinical significances of Beclin1, LC3 and mTOR in colorectal cancer.
Author:	Wu, Shuhua\|Sun, Chenbo\|Tian, Dong\|Li, Yangyang\|Gao, Xiangqian\|He, Shuang\|Li, Tangyue
PMID:	26097572

53.
Journal:	Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2015 Jul;31(7):898-904.
Title:	[ASPP2 inhibits oxaliplatin-induced autophagy and promotes apoptosis of colon cancer cells].
Author:	Wang, Bishi\|Qiao, Luxin\|Shi, Ying\|Feng, Xiaokun\|Chen, Dexi\|Guo, Hongliang
PMID:	26146058

54.
Journal:	Asian Pac J Cancer Prev. 2015;16(12):4981-5.
Title:	Aldose Reductase Inhibitor Fidarestat as a Promising Drug Targeting Autophagy in Colorectal Carcinoma: a Pilot Study.
Author:	Pandey, Saumya
PMID:	26163626

55.
Journal:	Clin Exp Metastasis. 2015 Oct;32(7):677-87.
Title:	Suppression of lung metastases by the CD26/DPP4 inhibitor Vildagliptin in mice.
Author:	Jang, Jae-Hwi\|Baerts, Lesley\|Waumans, Yannick\|De Meester, Ingrid\|Yamada, Yoshito\|Limani, Perparim\|Gil-Bazo, Ignacio\|Weder, Walter\|Jungraithmayr, Wolfgang
PMID:	26233333

56.
Journal:	PLoS One. 2015 Aug 6;10(8):e0134676.
Title:	Lithium Modulates Autophagy in Esophageal and Colorectal Cancer Cells and Enhances the Efficacy of Therapeutic Agents In Vitro and In Vivo.
Author:	O'Donovan, Tracey R\|Rajendran, Simon\|O'Reilly, Seamus\|O'Sullivan, Gerald C\|McKenna, Sharon L
PMID:	26248051

57.
Journal:	Lasers Med Sci. 2015 Sep;30(7):1967-75.
Title:	Targeted inhibition of p38MAPK-enhanced autophagy in SW620 cells resistant to photodynamic therapy-induced apoptosis.
Author:	Xue, Qin\|Wang, Pan\|Wang, Xiaobing\|Zhang, Kun\|Liu, Quanhong
PMID:	26254783

58.
Journal:	Eur J Pharmacol. 2015 Oct 15;765:217-27.
Title:	Blockade of autophagy enhances proapoptotic potential of BI-69A11, a novel Akt inhibitor, in colon carcinoma.
Author:	Pal, Ipsita\|Parida, Sheetal\|Prashanth Kumar, B N\|Banik, Payel\|Kumar Dey, Kaushik\|Chakraborty, Sandipan\|Bhutia, Sujit K\|Mandal, Mahitosh
PMID:	26306675

59.
Journal:	Radiother Oncol. 2015 Sep;116(3):409-16.
Title:	AMPK-independent autophagy promotes radioresistance of human tumor cells under clinical relevant hypoxia in vitro.
Author:	Chaachouay, Hassan\|Fehrenbacher, Birgit\|Toulany, Mahmoud\|Schaller, Martin\|Multhoff, Gabriele\|Rodemann, H Peter
PMID:	26318663

60.
Journal:	Hum Pathol. 2015 Nov;46(11):1752-9.
Title:	Autophagy-related genes Raptor, Rictor, and Beclin1 expression and relationship with multidrug resistance in colorectal carcinoma.
Author:	Shuhua, Wu\|Chenbo, Sun\|Yangyang, Li\|Xiangqian, Gao\|Shuang, He\|Tangyue, Li\|Dong, Tian
PMID:	26363527

61.
Journal:	Mol Carcinog. 2016 Feb;55(2):220-9.
Title:	Rheb promotes cancer cell survival through p27Kip1-dependent activation of autophagy.
Author:	Campos, Tania\|Ziehe, Javiera\|Palma, Mario\|Escobar, David\|Tapia, Julio C\|Pincheira, Roxana\|Castro, Ariel F
PMID:	25594310

62.
Journal:	Int J Mol Med. 2016 Jan;37(1):126-32.
Title:	Orexin A induces autophagy in HCT-116 human colon cancer cells through the ERK signaling pathway.
Author:	Wen, Jing\|Zhao, Yuyan\|Guo, Lei
PMID:	26572581

63.
Journal:	Oncol Rep. 2016 Mar;35(3):1255-64.
Title:	Selenite-induced autophagy antagonizes apoptosis in colorectal cancer cells in vitro and in vivo.
Author:	Yang, Yang\|Luo, Hui\|Hui, Kaiyuan\|Ci, Yali\|Shi, Kejian\|Chen, Ge\|Shi, Lei\|Xu, Caimin
PMID:	26676801

64.
Journal:	Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2016 Jan;32(1):34-8.
Title:	[Keratin 18 phosphorylation increases autophagy of colorectal cancer HCT116 cells and enhanced its sensitivity to oxaliplatin].
Author:	Yan, Xiaodong\|Shi, Ying\|Kou, Buxin\|Zhu, Zhenyu\|Chai, Jie\|Chen, Dexi\|Guo, Hongliang
PMID:	26728375

65.
Journal:	Oncotarget. 2016 Feb 23;7(8):9188-221.
Title:	BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells.
Author:	Goulielmaki, Maria\|Koustas, Evangelos\|Moysidou, Eirini\|Vlassi, Margarita\|Sasazuki, Takehiko\|Shirasawa, Senji\|Zografos, George\|Oikonomou, Eftychia\|Pintzas, Alexander
PMID:	26802026

66.
Journal:	Arch Biochem Biophys. 2016 Apr 15;596:84-98.
Title:	CHNQ, a novel 2-Chloro-1,4-naphthoquinone derivative of quercetin, induces oxidative stress and autophagy both in vitro and in vivo.
Author:	Enayat, Shabnam\|Seyma Ceyhan, M\|Taskoparan, Betul\|Stefek, Milan\|Banerjee, Sreeparna
PMID:	26946942

67.
Journal:	Am J Cancer Res. 2016 Jun 1;6(6):1345-57. eCollection 2016.
Title:	BH3 mimetic ABT-737 sensitizes colorectal cancer cells to ixazomib through MCL-1 downregulation and autophagy inhibition.
Author:	Yang, Lifeng\|Wan, Juefeng\|Xiao, Sheng\|Barkhouse, Darryll\|Zhu, Ji\|Li, Guichao\|Lu, Bo\|Zhang, Zhen
PMID:	27429848

68.
Journal:	World J Surg Oncol. 2016 Jul 22;14(1):189.
Title:	Prognostic relevance of autophagy-related markers LC3, p62/sequestosome 1, Beclin-1 and ULK1 in colorectal cancer patients with respect to KRAS mutational status.
Author:	Schmitz, Klaus Juergen\|Ademi, Ceflije\|Bertram, Stefanie\|Schmid, Kurt Werner\|Baba, Hideo Andreas
PMID:	27444698

69.
Journal:	Eur J Med Chem. 2016 Oct 21;122:611-618.
Title:	Autophagy regulates Selumetinib (AZD6244) induced-apoptosis in colorectal cancer cells.
Author:	Grasso, Silvina\|Pereira, Gustavo J S\|Palmeira-Dos-Santos, Caroline\|Calgarotto, Andrana K\|Martinez-Lacaci, Isabel\|Ferragut, Jose Antonio\|Smaili, Soraya S\|Bincoletto, Claudia
PMID:	27448918

70.
Journal:	Mol Med Rep. 2016 Sep;14(3):2548-54.
Title:	Co-expression of autophagic markers following photodynamic therapy in SW620 human colon adenocarcinoma cells.
Author:	Ziolkowska, Barbara\|Wozniak, Marta\|Ziolkowski, Piotr
PMID:	27485939

71.
Journal:	Genes (Basel). 2016 Oct 3;7(10). pii: genes7100083.
Title:	Downregulation of Enhancer of Zeste Homolog 2 (EZH2) is essential for the Induction of Autophagy and Apoptosis in Colorectal Cancer Cells.
Author:	Yao, Yizhou\|Hu, Hao\|Yang, Yong\|Zhou, Guoqiang\|Shang, Zengfu\|Yang, Xiaodong\|Sun, Kang\|Zhan, Shenghua\|Yu, Zhengyuan\|Li, Peiyao\|Pan, Guofeng\|Sun, Liang\|Zhu, Xinguo\|He, Songbing
PMID:	27706111

72.
Journal:	Oncol Rep. 2016 Dec;36(6):3559-3567.
Title:	Salidroside induces apoptosis and autophagy in human colorectal cancer cells through inhibition of PI3K/Akt/mTOR pathway.
Author:	Fan, Xiang-Jun\|Wang, Yao\|Wang, Lei\|Zhu, Mingyan
PMID:	27748934

73.
Journal:	Oncol Rep. 2016 Dec;36(6):3682-3690.
Title:	Downregulation of YEATS4 by miR-218 sensitizes colorectal cancer cells to L-OHP-induced cell apoptosis by inhibiting cytoprotective autophagy.
Author:	Fu, Qiang\|Cheng, Jing\|Zhang, Jindai\|Zhang, Yonglei\|Chen, Xiaobing\|Xie, Jianguo\|Luo, Suxia
PMID:	27779719

74.
Journal:	Oncotarget. 2016 Nov 29;7(48):79617-79628.
Title:	miR-31 affects colorectal cancer cells by inhibiting autophagy in cancer-associated fibroblasts.
Author:	Yang, Xiaodong\|Xu, Xiaohui\|Zhu, Junjia\|Zhang, Shuyu\|Wu, Yong\|Wu, Yongyou\|Zhao, Kui\|Xing, Chungen\|Cao, Jianping\|Zhu, Hong\|Li, Ming\|Ye, Zhenyu\|Peng, Wei
PMID:	27793031

75.
Journal:	J Ethnopharmacol. 2017 Apr 18;202:20-27.
Title:	Pogostone induces autophagy and apoptosis involving PI3K/Akt/mTOR axis in human colorectal carcinoma HCT116 cells.
Author:	Cao, Zhi-Xing\|Yang, Yu-Ting\|Yu, Si\|Li, Yu-Zhi\|Wang, Wen-Wen\|Huang, Jing\|Xie, Xiao-Fang\|Xiong, Liang\|Lei, Song\|Peng, Cheng
PMID:	27416805

76.
Journal:	Biomol Ther (Seoul). 2017 May 1;25(3):315-320.
Title:	Reduced Autophagy in 5-Fluorouracil Resistant Colon Cancer Cells.
Author:	Yao, Cheng Wen\|Kang, Kyoung Ah\|Piao, Mei Jing\|Ryu, Yea Seong\|Fernando, Pattage Madushan Dilhara Jayatissa\|Oh, Min Chang\|Park, Jeong Eon\|Shilnikova, Kristina\|Na, Soo-Young\|Jeong, Seung Uk\|Boo, Sun-Jin\|Hyun, Jin Won
PMID:	27737524

77.
Journal:	Nutr Cancer. 2017 Jan;69(1):44-55.
Title:	Koelreuteria Formosana Extract Induces Growth Inhibition and Cell Death in Human Colon Carcinoma Cells via G2/M Arrest and LC3-II Activation-Dependent Autophagy.
Author:	Horng, Chi-Ting\|Wu, Yueh-Jung\|Chen, Pei-Ni\|Chu, Shu-Chen\|Tsai, Chun-Miao\|Hsieh, Yih-Shou
PMID:	27880045

78.
Journal:	J Pineal Res. 2017 Apr;62(3).
Title:	Melatonin prevents mitochondrial dysfunction and promotes neuroprotection by inducing autophagy during oxaliplatin-evoked peripheral neuropathy.
Author:	Areti, Aparna\|Komirishetty, Prashanth\|Akuthota, Manasaveena\|Malik, Rayaz A\|Kumar, Ashutosh
PMID:	28118492

79.
Journal:	Sci Rep. 2017 Feb 14;7:42591.
Title:	New findings of silica nanoparticles induced ER autophagy in human colon cancer cell.
Author:	Wei, Fujing\|Wang, Yimin\|Luo, Zewei\|Li, Yu\|Duan, Yixiang
PMID:	28195184

80.
Journal:	Cell Death Differ. 2017 Jun;24(6):1045-1062.
Title:	mTORC1-independent autophagy regulates receptor tyrosine kinase phosphorylation in colorectal cancer cells via an mTORC2-mediated mechanism.
Author:	Lampada, Aikaterini\|O'Prey, James\|Szabadkai, Gyorgy\|Ryan, Kevin M\|Hochhauser, Daniel\|Salomoni, Paolo
PMID:	28475179

81.
Journal:	Oncotarget. 2017 Jun 20;8(25):41401-41411.
Title:	Trans-scirpusin A showed antitumor effects via autophagy activation and apoptosis induction of colorectal cancer cells.
Author:	Hong, Eun-Hye\|Heo, Eun-Young\|Song, Jae-Hyoung\|Kwon, Bo-Eun\|Lee, Jae-Young\|Park, Yaejeong\|Kim, Jinwoong\|Chang, Sun-Young\|Chin, Young-Won\|Jeon, Sang-Min\|Ko, Hyun-Jeong
PMID:	28489607

82.
Journal:	Rom J Morphol Embryol. 2017;58(1):27-31.
Title:	Autophagy in aging and disease.
Author:	Filfan, Madalina\|Sandu, Raluca Elena\|Zavaleanu, Alexandra Daniela\|GresiTa, Andrei\|Glavan, Daniela Gabriela\|Olaru, Denissa Greta\|Popa-Wagner, Aurel
PMID:	28523294

83.
Journal:	Stem Cells Int. 2017;2017:4782820.
Title:	The Effect of Pyrroloquinoline Quinone on the Expression of WISP1 in Traumatic Brain Injury.
Author:	Ye, Yongqi\|Zhang, Pengju\|Qian, Yuhang\|Yin, Baoxin\|Yan, Meijuan
PMID:	28883836

84.
Journal:	Oncotarget. 2017 Aug 4;8(35):59058-59067.
Title:	Beclin 1 and LC3 as predictive biomarkers for metastatic colorectal carcinoma.
Author:	Zhao, Hong\|Yang, Maopeng\|Zhao, Bin
PMID:	28938618

85.
Journal:	J Cell Physiol. 2018 Jan;233(1):497-505.
Title:	Autophagy mediates cytotoxicity of human colorectal cancer cells treated with garcinielliptone FC.
Author:	Won, Shen-Jeu\|Yen, Cheng-Hsin\|Lin, Ting-Yu\|Jiang-Shieh, Ya-Fen\|Lin, Chun-Nan\|Chen, Jyun-Ti\|Su, Chun-Li
PMID:	28294332

86.
Journal:	Biochimie. 2018 Jan;144:21-27.
Title:	LncRNA CPS1-IT1 suppresses EMT and metastasis of colorectal cancer by inhibiting hypoxia-induced autophagy through inactivation of HIF-1alpha.
Author:	Zhang, Wei\|Yuan, Weitang\|Song, Junmin\|Wang, Shijun\|Gu, Xiaoming
PMID:	29017924

87.
Journal:	Toxicol In Vitro. 2018 Mar;47:129-136.
Title:	In vitro antitumor effect of a lignan isolated from Combretum fruticosum, trachelogenin, in HCT-116 human colon cancer cells.
Author:	Moura, A F\|Lima, K S B\|Sousa, T S\|Marinho-Filho, J D B\|Pessoa, C\|Silveira, E R\|Pessoa, O D L\|Costa-Lotufo, L V\|Moraes, M O\|Araujo, A J
PMID:	29174024

88.
Journal:	Int J Mol Med. 2018 Mar;41(3):1305-1314.
Title:	Codonopis bulleynana Forest ex Diels inhibits autophagy and induces apoptosis of colon cancer cells by activating the NF-kappaB signaling pathway.
Author:	Luan, Yunpeng\|Li, Yanmei\|Zhu, Lina\|Zheng, Shuangqing\|Mao, Dechang\|Chen, Zhuxue\|Cao, Yong
PMID:	29286074

89.
Journal:	Oncogenesis. 2018 Feb 20;7(2):16.
Title:	Inhibition of ATG12-mediated autophagy by miR-214 enhances radiosensitivity in colorectal cancer.
Author:	Hu, J L\|He, G Y\|Lan, X L\|Zeng, Z C\|Guan, J\|Ding, Y\|Qian, X L\|Liao, W T\|Ding, Y Q\|Liang, L
PMID:	29459645

90.
Journal:	Cell Oncol (Dordr). 2018 Jun;41(3):297-317.
Title:	Inhibition of autophagy enhances DENSpm-induced apoptosis in human colon cancer cells in a p53 independent manner.
Author:	Gurkan, Ajda Coker\|Arisan, Elif Damla\|Yerlikaya, Pinar Obakan\|Ilhan, Halime\|Unsal, Narcin Palavan
PMID:	29492901

91.
Journal:	Theranostics. 2018 Mar 28;8(9):2477-2487.
Title:	Graphene oxide sensitizes cancer cells to chemotherapeutics by inducing early autophagy events, promoting nuclear trafficking and necrosis.
Author:	Lin, Kuan-Chen\|Lin, Mei-Wei\|Hsu, Mu-Nung\|Yu-Chen, Guan\|Chao, Yu-Chan\|Tuan, Hsing-Yu\|Chiang, Chi-Shiun\|Hu, Yu-Chen
PMID:	29721093

92.
Journal:	Int J Mol Med. 2018 Sep;42(3):1295-1304.
Title:	Artesunate induces apoptosis and autophagy in HCT116 colon cancer cells, and autophagy inhibition enhances the artesunateinduced apoptosis.
Author:	Jiang, Feng\|Zhou, Jin-Yong\|Zhang, Dan\|Liu, Ming-Hao\|Chen, Yu-Gen
PMID:	29901098

93.
Journal:	Oncol Lett. 2018 Jun;15(6):9719-9724.
Title:	Activation of the SphK1/ERK/p-ERK pathway promotes autophagy in colon cancer cells.
Author:	Xu, Chunyan\|Zhang, Wenlu\|Liu, Shiquan\|Wu, Wenhong\|Qin, Mengbin\|Huang, Jiean
PMID:	29928348

94.
Journal:	Eur J Med Chem. 2018 Aug 5;156:344-367.
Title:	Discovery of the cancer cell selective dual acting anti-cancer agent (Z)-2-(1H-indol-3-yl)-3-(isoquinolin-5-yl)acrylonitrile (A131).
Author:	See, Cheng Shang\|Kitagawa, Mayumi\|Liao, Pei-Ju\|Lee, Kyung Hee\|Wong, Jasmine\|Lee, Sang Hyun\|Dymock, Brian W
PMID:	30015072

95.
Journal:	Biomater Sci. 2018 Aug 21;6(9):2508-2517.
Title:	Autophagy is an important action mode for functionalized selenium nanoparticles to exhibit anti-colorectal cancer activity.
Author:	Huang, Guanning\|Liu, Zumei\|He, Lizhen\|Luk, Kar-Him\|Cheung, Siu-To\|Wong, Ka-Hing\|Chen, Tianfeng
PMID:	30091749

96.
Journal:	Autophagy. 2018 Sep 20:1-17.
Title:	Discovery of a small molecule targeting autophagy via ATG4B inhibition and cell death of colorectal cancer cells in vitro and in vivo.
Author:	Fu, Yuanyuan\|Hong, Liang\|Xu, Jiecheng\|Zhong, Guoping\|Gu, Qiong\|Gu, Qianqian\|Guan, Yanping\|Zheng, Xueping\|Dai, Qi\|Luo, Xia\|Liu, Cui\|Huang, Zhiying\|Yin, Xiao-Ming\|Liu, Peiqing\|Li, Min
PMID:	30176161

97.
Journal:	Biomed Pharmacother. 2018 Sep 15;108:331-337.
Title:	Silencing of cadherin-17 enhances apoptosis and inhibits autophagy in colorectal cancer cells.
Author:	Tian, Xia\|Han, Zheng\|Zhu, Qingxi\|Tan, Jie\|Liu, Weijie\|Wang, Yanfen\|Chen, Wei\|Zou, Yanli\|Cai, Yishan\|Huang, Shasha\|Chen, Aifang\|Zhan, Ting\|Huang, Min\|Liu, Meng\|Huang, Xiaodong
PMID:	30227326

98.
Journal:	J Physiol Biochem. 2018 Oct 25. pii: 10.1007/s13105-018-0651-z.
Title:	Sodium butyrate induces autophagy in colorectal cancer cells through LKB1/AMPK signaling.
Author:	Luo, Shunli\|Li, Ziyin\|Mao, Lianzhi\|Chen, Siqiang\|Sun, Suxia
PMID:	30362049

99.
Journal:	Biomed Pharmacother. 2018 Oct 1;108:1208-1215.
Title:	Ophiopogonin B induces the autophagy and apoptosis of colon cancer cells by activating JNK/c-Jun signaling pathway.
Author:	Gao, Guang-Yi\|Ma, Jun\|Lu, Peng\|Jiang, Xuan\|Chang, Cheng
PMID:	30372822

100.
Journal:	Med Oncol. 2018 Oct 29;35(12):159.
Title:	The Influence of Tumor Microenvironment on ATG4D Gene Expression in Colorectal Cancer Patients.
Author:	Gil, Justyna\|Ramsey, David\|Pawlowski, Pawel\|Szmida, Elzbieta\|Leszczynski, Przemyslaw\|Bebenek, Marek\|Sasiadek, Maria M
PMID:	30374741

101.
Journal:	FEBS J. 2018 Oct 30.
Title:	2-Deoxyglucose has distinct and cell line-specific effects on the survival of different cancer cells upon antitumor drug treatment.
Author:	Maximchik, Polina\|Abdrakhmanov, Alibek\|Inozemtseva, Evgeniya\|Tyurin-Kuzmin, Pyotr A\|Zhivotovsky, Boris\|Gogvadze, Vladimir
PMID:	30375744