Primary Site >> Colorectal Cancer

Gene >> MAD2L1

Journal: Jpn J Cancer Res. 1999 Aug;90(8):837-40.
Title: Mutational inactivation of mitotic checkpoint genes, hsMAD2 and hBUB1, is rare in sporadic digestive tract cancers.
Author: Imai, Y|Shiratori, Y|Kato, N|Inoue, T|Omata, M
PMID: 10543255
Journal: World J Gastroenterol. 2003 Sep;9(9):1972-5.
Title: Mad2 and p53 expression profiles in colorectal cancer and its clinical significance.
Author: Li, Gang-Qiang|Li, Hao|Zhang, Hong-Fu
PMID: 12970887
Journal: Carcinogenesis. 2004 Mar;25(3):349-57. Epub 2003 Nov 21.
Title: Gene modulation by Cox-1 and Cox-2 specific inhibitors in human colorectal carcinoma cancer cells.
Author: Bottone, Frank G Jr|Martinez, Jeanelle M|Alston-Mills, Brenda|Eling, Thomas E
PMID: 14633654
Journal: Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8699-704.
Title: Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint.
Author: Kops, Geert J P L|Foltz, Daniel R|Cleveland, Don W
PMID: 15159543
Journal: World J Gastroenterol. 2004 Nov 1;10(21):3218-20.
Title: Mad2 and p27 expression profiles in colorectal cancer and its clinical significance.
Author: Li, Gang-Qiang|Zhang, Hong-Fu
PMID: 15457580
Journal: Int J Cancer. 2007 Jan 1;120(1):207-11.
Title: Expression of the mitotic checkpoint gene MAD2L2 has prognostic significance in colon cancer.
Author: Rimkus, Caroline|Friederichs, Jan|Rosenberg, Robert|Holzmann, Bernhard|Siewert, Jorg-Rudiger|Janssen, Klaus-Peter
PMID: 17044027
Journal: Cell Cycle. 2007 Feb 1;6(3):339-52. Epub 2007 Feb 3.
Title: c-MYC delays prometaphase by direct transactivation of MAD2 and BubR1: identification of mechanisms underlying c-MYC-induced DNA damage and chromosomal instability.
Author: Menssen, Antje|Epanchintsev, Alexey|Lodygin, Dmitri|Rezaei, Nousin|Jung, Peter|Verdoodt, Berlinda|Diebold, Joachim|Hermeking, Heiko
PMID: 17297307
Journal: J Clin Pathol. 2007 Dec;60(12):1403-8.
Title: Spindle proteins Aurora A and BUB1B, but not Mad2, are aberrantly expressed in dysplastic mucosa of patients with longstanding ulcerative colitis.
Author: Burum-Auensen, E|Deangelis, P M|Schjolberg, A R|Roislien, Jo|Andersen, S N|Clausen, O P F
PMID: 17322345
Journal: Cancer Biol Ther. 2007 Apr;6(4):525-33.
Title: High copy amplification of the Aurora-A gene is associated with chromosomal instability phenotype in human colorectal cancers.
Author: Nishida, Naoshi|Nagasaka, Takeshi|Kashiwagi, Kazuhiro|Boland, C Richard|Goel, Ajay
PMID: 17457043
Journal: Gastroenterology. 2007 Jun;132(7):2448-58. Epub 2007 Mar 19.
Title: APC inactivation associates with abnormal mitosis completion and concomitant BUB1B/MAD2L1 up-regulation.
Author: Abal, Miguel|Obrador-Hevia, Antonia|Janssen, Klaus-Peter|Casadome, Laura|Menendez, Mireia|Carpentier, Sabrina|Barillot, Emmanuel|Wagner, Mechthild|Ansorge, Wilhelm|Moeslein, Gabriela|Fsihi, Hafida|Bezrookove, Vladimir|Reventos, Jaume|Louvard, Daniel|Capel
PMID: 17570218
Journal: Cell Prolif. 2008 Aug;41(4):645-59.
Title: Reduced level of the spindle checkpoint protein BUB1B is associated with aneuploidy in colorectal cancers.
Author: Burum-Auensen, E|DeAngelis, P M|Schjolberg, A R|Roislien, J|Mjaland, O|Clausen, O P F
PMID: 18699967
Journal: Anticancer Res. 2009 Nov;29(11):4381-7.
Title: Aneuploidy is associated with TP53 expression but not with BRCA1 or TERT expression in sporadic colorectal cancer.
Author: Schjolberg, Aasa R|Clausen, Ole Petter F|Burum-Auensen, Espen|De Angelis, Paula M
PMID: 20032382
Journal: Mol Biol Cell. 2009 May;20(9):2381-8.
Title: Oncogenic Adenomatous polyposis coli mutants impair the mitotic checkpoint through direct interaction with Mad2.
Author: Zhang, Jiayin|Neisa, Roberto|Mao, Yinghui
PMID: 19261806
Journal: Nutr Cancer. 2010;62(6):825-40.
Title: Hydrophobic bile acid-induced micronuclei formation, mitotic perturbations, and decreases in spindle checkpoint proteins: relevance to genomic instability in colon carcinogenesis.
Author: Payne, Claire M|Crowley-Skillicorn, Cheray|Bernstein, Carol|Holubec, Hana|Moyer, Mary Pat|Bernstein, Harris
PMID: 20661832
Journal: Oncol Rep. 2010 Oct;24(4):1029-34.
Title: Possibility of paclitaxel as an alternative radiosensitizer to 5-fluorouracil for colon cancer.
Author: Hiro, Junichiro|Inoue, Yasuhiro|Toiyama, Yuji|Yoshiyama, Shigeyuki|Tanaka, Koji|Mohri, Yasuhiko|Miki, Chikao|Kusunoki, Masato
PMID: 20811685
Journal: Cancer Lett. 2011 May 28;304(2):128-36.
Title: Therapeutic targeting of the mitotic spindle checkpoint through nanoparticle-mediated siRNA delivery inhibits tumor growth in vivo.
Author: Kaestner, Phillip|Aigner, Achim|Bastians, Holger
PMID: 21377782
Journal: Apoptosis. 2011 Aug;16(8):856-67.
Title: Shogaols at proapoptotic concentrations induce G(2)/M arrest and aberrant mitotic cell death associated with tubulin aggregation.
Author: Gan, Fei-Fei|Nagle, Amrita A|Ang, Xiaohui|Ho, Olivia Huixian|Tan, Sock-Hoon|Yang, Hong|Chui, Wai-Keung|Chew, Eng-Hui
PMID: 21598039
Journal: Biochem Pharmacol. 2014 Sep 1;91(1):31-9.
Title: Withaferin A modulates the Spindle assembly checkpoint by degradation of Mad2-Cdc20 complex in colorectal cancer cell lines.
Author: Das, Tania|Roy, Kumar Singha|Chakrabarti, Tulika|Mukhopadhyay, Sibabrata|Roychoudhury, Susanta
PMID: 24995417
Journal: Oncotarget. 2015 Jul 10;6(19):17342-53.
Title: Deregulation of HMGA1 expression induces chromosome instability through regulation of spindle assembly checkpoint genes.
Author: Pierantoni, Giovanna Maria|Conte, Andrea|Rinaldo, Cinzia|Tornincasa, Mara|Gerlini, Raffaele|Federico, Antonella|Valente, Davide|Medico, Enzo|Fusco, Alfredo
PMID: 26009897
Journal: Sci Rep. 2015 Jul 17;5:12202.
Title: MAD1L1 Arg558His and MAD2L1 Leu84Met interaction with smoking increase the risk of colorectal cancer.
Author: Zhong, Rong|Chen, Xiaohua|Chen, Xueqin|Zhu, Beibei|Lou, Jiao|Li, Jiaoyuan|Shen, Na|Yang, Yang|Gong, Yajie|Zhu, Ying|Yuan, Jing|Xia, Xiaoping|Miao, Xiaoping
PMID: 26183163
Journal: Cell Cycle. 2016;15(6):812-8.
Title: Hmga1 null mouse embryonic fibroblasts display downregulation of spindle assembly checkpoint gene expression associated to nuclear and karyotypic abnormalities.
Author: Pierantoni, Giovanna Maria|Conte, Andrea|Rinaldo, Cinzia|Tornincasa, Mara|Gerlini, Raffaele|Valente, Davide|Izzo, Antonella|Fusco, Alfredo
PMID: 26889953
Journal: Oncol Lett. 2016 Dec;12(6):5092-5098.
Title: Identification of potential therapeutic targets for colorectal cancer by bioinformatics analysis.
Author: Yan, Ming|Song, Maomin|Bai, Rixing|Cheng, Shi|Yan, Wenmao
PMID: 28105216
Journal: Oncotarget. 2017 Mar 28;8(13):21229-21240.
Title: TRAP1 protein signature predicts outcome in human metastatic colorectal carcinoma.
Author: Maddalena, Francesca|Simeon, Vittorio|Vita, Giulia|Bochicchio, Annamaria|Possidente, Luciana|Sisinni, Lorenza|Lettini, Giacomo|Condelli, Valentina|Matassa, Danilo Swann|Li Bergolis, Valeria|Fersini, Alberto|Romito, Sante|Aieta, Michele|Ambrosi, Antonio|Es
PMID: 28177905
Journal: Mol Cell Probes. 2018 Feb;37:39-47.
Title: Identification of genes involved in the four stages of colorectal cancer: Gene expression profiling.
Author: Shi, Guiling|Wang, Yijia|Zhang, Chunze|Zhao, Zhenying|Sun, Xiuying|Zhang, Shiwu|Fan, Jinling|Zhou, Cunxia|Zhang, Jihong|Zhang, Huijuan|Liu, Jun
PMID: 29179987
Journal: Biochem Biophys Res Commun. 2018 Sep 18;503(4):2286-2292.
Title: Inhibition of eukaryotic translation initiation factor 4E is effective against chemo-resistance in colon and cervical cancer.
Author: Xi, Changlei|Wang, Ling|Yu, Jie|Ye, Hui|Cao, Longlei|Gong, Zhilin
PMID: 29959920