Primary Site >> Liver Cancer

Gene >> LRP6

Journal: Ai Zheng. 2004 Sep;23(9):985-91.
Title: Correlation between methylation profile of promoter cpg islands of seven metastasis-associated genes and their expression states in six cell lines of liver origin.
Author: Li, Jian-Liang|Fei, Qi|Yu, Jian|Zhang, Hong-Yu|Wang, Peng|Zhu, Jing-De
PMID: 15363188
Journal: Int J Mol Med. 2007 Mar;19(3):529-33.
Title: Comparative integromics on FZD7 orthologs: conserved binding sites for PU.1, SP1, CCAAT-box and TCF/LEF/SOX transcription factors within 5'-promoter region of mammalian FZD7 orthologs.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 17273804
Journal: Mol Cancer. 2009 Oct 22;8:90.
Title: Canonical Wnt signaling is antagonized by noncanonical Wnt5a in hepatocellular carcinoma cells.
Author: Yuzugullu, Haluk|Benhaj, Khemais|Ozturk, Nuri|Senturk, Serif|Celik, Emine|Toylu, Asli|Tasdemir, Nilgun|Yilmaz, Mustafa|Erdal, Esra|Akcali, Kamil Can|Atabey, Nese|Ozturk, Mehmet
PMID: 19849855
Journal: PLoS One. 2012;7(5):e36565.
Title: Upregulation of the Wnt co-receptor LRP6 promotes hepatocarcinogenesis and enhances cell invasion.
Author: Tung, Edmund Kwok-Kwan|Wong, Betty Yin-Chi|Yau, Tai-On|Ng, Irene Oi-Lin
PMID: 22570728
Journal: J Nat Sci Biol Med. 2013 Jan;4(1):126-33.
Title: Influence of limonin on Wnt signalling molecule in HepG2 cell lines.
Author: Langeswaran, K|Gowthamkumar, S|Vijayaprakash, S|Revathy, R|Balasubramanian, M P
PMID: 23633848
Journal: FEBS Lett. 2014 May 21;588(10):1913-20.
Title: miR-202 suppresses cell proliferation in human hepatocellular carcinoma by downregulating LRP6 post-transcriptionally.
Author: Zhang, Yi|Zheng, Dayong|Xiong, Yan|Xue, Chengbiao|Chen, Gen|Yan, Bibo|Ye, Qifa
PMID: 24704686
Journal: J Transl Med. 2014 Sep 22;12:259.
Title: MiR-126-3p suppresses tumor metastasis and angiogenesis of hepatocellular carcinoma by targeting LRP6 and PIK3R2.
Author: Du, Chengli|Lv, Zhen|Cao, Linping|Ding, Chaofeng|Gyabaah, Owusu-Ansah K|Xie, Haiyang|Zhou, Lin|Wu, Jian|Zheng, Shusen
PMID: 25240815
Journal: Cell Stem Cell. 2015 Jul 2;17(1):47-59.
Title: TPO-Induced Metabolic Reprogramming Drives Liver Metastasis of Colorectal Cancer CD110+ Tumor-Initiating Cells.
Author: Wu, ZhengMing|Wei, Dong|Gao, WenChao|Xu, YuTing|Hu, ZhiQian|Ma, ZhenYu|Gao, ChunFang|Zhu, XiaoYan|Li, QingQuan
PMID: 26140605
Journal: Cell Mol Gastroenterol Hepatol. 2015 Sep 1;1(5):535-549.e14.
Title: Pigment Epithelium-Derived Factor (PEDF) Inhibits Wnt/beta-catenin Signaling in the Liver.
Author: Protiva, Petr|Gong, Jingjing|Sreekumar, Bharath|Torres, Richard|Zhang, Xuchen|Belinsky, Glenn S|Cornwell, Mona|Crawford, Susan E|Iwakiri, Yasuko|Chung, Chuhan
PMID: 26473164
Journal: Oncotarget. 2015 Apr 10;6(10):7866-79.
Title: Downregulation of miR-432 activates Wnt/beta-catenin signaling and promotes human hepatocellular carcinoma proliferation.
Author: Jiang, Nan|Chen, Wen-Jie|Zhang, Jian-Wen|Xu, Chi|Zeng, Xian-Cheng|Zhang, Tong|Li, Yang|Wang, Guo-Ying
PMID: 25797263
Journal: Oncotarget. 2016 Nov 29;7(48):79774-79786.
Title: Plasma glutamate carboxypeptidase is a negative regulator in liver cancer metastasis.
Author: Lee, Jae-Hye|Cho, Hyun-Soo|Lee, Jeong-Ju|Jun, Soo Young|Ahn, Jun-Ho|Min, Ju-Sik|Yoon, Ji-Yong|Choi, Min-Hyuk|Jeon, Su-Jin|Lim, Jung Hwa|Jung, Cho-Rok|Kim, Dae-Soo|Kim, Hyun-Taek|Factor, Valentina M|Lee, Yun-Han|Thorgeirsson, Snorri S|Kim, Cheol-Hee|Kim, N
PMID: 27806330
Journal: Bull Cancer. 2017 Apr;104(4):311-320.
Title: A single nucleotide variant in microRNA-1269a promotes the occurrence and process of hepatocellular carcinoma by targeting to oncogenes SPATS2L and LRP6.
Author: Min, Pei|Li, Wenshuai|Zeng, Deqing|Ma, Yanyun|Xu, Diannan|Zheng, Wanwei|Tang, Feng|Chen, Jian|Shi, Jianping|Hu, Heping|Wang, Jiucun|Yang, Dongqin|Liu, Jie|Zhang, Jun|Zhang, Mingqing
PMID: 28081866
Journal: Gastroenterology. 2017 May;152(6):1477-1491.
Title: Stearoyl-CoA Desaturase Promotes Liver Fibrosis and Tumor Development in Mice via a Wnt Positive-Signaling Loop by Stabilization of Low-Density Lipoprotein-Receptor-Related Proteins 5 and 6.
Author: Lai, Keane K Y|Kweon, Soo-Mi|Chi, Feng|Hwang, Edward|Kabe, Yasuaki|Higashiyama, Reiichi|Qin, Lan|Yan, Rui|Wu, Raymond P|Lai, Keith|Fujii, Naoaki|French, Samuel|Xu, Jun|Wang, Jian-Ying|Murali, Ramachandran|Mishra, Lopa|Lee, Ju-Seog|Ntambi, James M|Tsukamot
PMID: 28143772
Journal: J Exp Clin Cancer Res. 2017 Sep 4;36(1):117.
Title: Maintenance of stemness is associated with the interation of LRP6 and heparin-binding protein CCN2 autocrined by hepatocellular carcinoma.
Author: Jia, Qingan|Bu, Yang|Wang, Zhiming|Chen, Bendong|Zhang, Qiangbo|Yu, Songning|Liu, Qingguang
PMID: 28870205
Journal: Zhongguo Zhong Yao Za Zhi. 2017 Oct;42(20):3990-3995.
Title: [Effects of aqueous extracts of gecko on stemness of hepatocellular carcinoma].
Author: Huang, Hui-Ling|Zhang, Ya-Lan|Chen, Wen-Fa|Wu, Chun-Ling
PMID: 29243438
Journal: Cell Death Differ. 2018 Aug;25(8):1426-1441.
Title: Cripto-1 contributes to stemness in hepatocellular carcinoma by stabilizing Dishevelled-3 and activating Wnt/beta-catenin pathway.
Author: Lo, Regina Cheuk-Lam|Leung, Carmen Oi-Ning|Chan, Kristy Kwan-Shuen|Ho, Daniel Wai-Hung|Wong, Chun-Ming|Lee, Terence Kin-Wah|Ng, Irene Oi-Lin
PMID: 29445127
Journal: Acta Pharm Sin B. 2018 Jul;8(4):575-586.
Title: Garlic-derived compound S-allylmercaptocysteine inhibits hepatocarcinogenesis through targeting LRP6/Wnt pathway.
Author: Xiao, Jia|Xing, Feiyue|Liu, Yingxia|Lv, Yi|Wang, Xiaogang|Ling, Ming-Tat|Gao, Hao|Ouyang, Songying|Yang, Min|Zhu, Jiang|Xia, Yu|So, Kwok-Fai|Tipoe, George L
PMID: 30109182