Primary Site >> Liver Cancer
Gene >> LRP6
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Ref: Correlation between methylation profile of promoter cpg islands of seven metastasis-associated genes and their expression states in six cell lines of liver origin. PMID: 15363188 |
Ref: Comparative integromics on FZD7 orthologs: conserved binding sites for PU.1, SP1, CCAAT-box and TCF/LEF/SOX transcription factors within 5'-promoter region of mammalian FZD7 orthologs. PMID: 17273804 |
Ref: Canonical Wnt signaling is antagonized by noncanonical Wnt5a in hepatocellular carcinoma cells. PMID: 19849855 |
Ref: Upregulation of the Wnt co-receptor LRP6 promotes hepatocarcinogenesis and enhances cell invasion. PMID: 22570728 |
Ref: Influence of limonin on Wnt signalling molecule in HepG2 cell lines. PMID: 23633848 |
Ref: miR-202 suppresses cell proliferation in human hepatocellular carcinoma by downregulating LRP6 post-transcriptionally. PMID: 24704686 Ref: MiR-126-3p suppresses tumor metastasis and angiogenesis of hepatocellular carcinoma by targeting LRP6 and PIK3R2. PMID: 25240815 |
Ref: Downregulation of miR-432 activates Wnt/beta-catenin signaling and promotes human hepatocellular carcinoma proliferation. PMID: 25797263 Ref: TPO-Induced Metabolic Reprogramming Drives Liver Metastasis of Colorectal Cancer CD110+ Tumor-Initiating Cells. PMID: 26140605 Ref: Pigment Epithelium-Derived Factor (PEDF) Inhibits Wnt/beta-catenin Signaling in the Liver. PMID: 26473164 |
Ref: Plasma glutamate carboxypeptidase is a negative regulator in liver cancer metastasis. PMID: 27806330 |
Ref: A single nucleotide variant in microRNA-1269a promotes the occurrence and process of hepatocellular carcinoma by targeting to oncogenes SPATS2L and LRP6. PMID: 28081866 Ref: Stearoyl-CoA Desaturase Promotes Liver Fibrosis and Tumor Development in Mice via a Wnt Positive-Signaling Loop by Stabilization of Low-Density Lipoprotein-Receptor-Related Proteins 5 and 6. PMID: 28143772 Ref: Maintenance of stemness is associated with the interation of LRP6 and heparin-binding protein CCN2 autocrined by hepatocellular carcinoma. PMID: 28870205 Ref: [Effects of aqueous extracts of gecko on stemness of hepatocellular carcinoma]. PMID: 29243438 |
Ref: Cripto-1 contributes to stemness in hepatocellular carcinoma by stabilizing Dishevelled-3 and activating Wnt/beta-catenin pathway. PMID: 29445127 Ref: Garlic-derived compound S-allylmercaptocysteine inhibits hepatocarcinogenesis through targeting LRP6/Wnt pathway. PMID: 30109182 |