Primary Site >> Colorectal Cancer
Gene >> LRP6
| 1. | |||||||||||
| Journal: | Oncogene. 2005 Feb 3;24(6):1098-103. | ||||||||||
| Title: | The Wnt antagonist DICKKOPF-1 gene is a downstream target of beta-catenin/TCF and is downregulated in human colon cancer. | ||||||||||
| Author: | Gonzalez-Sancho, Jose Manuel|Aguilera, Oscar|Garcia, Jose Miguel|Pendas-Franco, Natalia|Pena, Cristina|Cal, Santiago|Garcia de Herreros, Antonio|Bonilla, Felix|Munoz, Alberto | ||||||||||
| PMID: | 15592505 | ||||||||||
| 2. | |||||||||||
| Journal: | Int J Cancer. 2006 Oct 15;119(8):1837-42. | ||||||||||
| Title: | Mutations within Wnt pathway genes in sporadic colorectal cancers and cell lines. | ||||||||||
| Author: | Suraweera, Nirosha|Robinson, James|Volikos, Emmanuoil|Guenther, Thomas|Talbot, Ian|Tomlinson, Ian|Silver, Andrew | ||||||||||
| PMID: | 16708370 | ||||||||||
| 3. | |||||||||||
| Journal: | Clin Cancer Res. 2007 Jan 15;13(2 Pt 1):415-20. | ||||||||||
| Title: | Gene expression signature and the prediction of ulcerative colitis-associated colorectal cancer by DNA microarray. | ||||||||||
| Author: | Watanabe, Toshiaki|Kobunai, Takashi|Toda, Etsuko|Kanazawa, Takamitsu|Kazama, Yoshihiro|Tanaka, Junichiro|Tanaka, Toshiaki|Yamamoto, Yoko|Hata, Keisuke|Kojima, Tetsu|Yokoyama, Tadashi|Konishi, Tsuyoshi|Okayama, Yoshihiro|Sugimoto, Yoshikazu|Oka, Toshinori| | ||||||||||
| PMID: | 17255260 | ||||||||||
| 4. | |||||||||||
| Journal: | Int J Mol Med. 2007 Mar;19(3):529-33. | ||||||||||
| Title: | Comparative integromics on FZD7 orthologs: conserved binding sites for PU.1, SP1, CCAAT-box and TCF/LEF/SOX transcription factors within 5'-promoter region of mammalian FZD7 orthologs. | ||||||||||
| Author: | Katoh, Masuko|Katoh, Masaru | ||||||||||
| PMID: | 17273804 | ||||||||||
| 5. | |||||||||||
| Journal: | Oncogene. 2008 Aug 28;27(37):5075-80. | ||||||||||
| Title: | Snail promotes Wnt target gene expression and interacts with beta-catenin. | ||||||||||
| Author: | Stemmer, V|de Craene, B|Berx, G|Behrens, J | ||||||||||
| PMID: | 18469861 | ||||||||||
| 6. | |||||||||||
| Journal: | Int J Mol Med. 2009 Aug;24(2):247-51. | ||||||||||
| Title: | Integrative genomic analyses of WNT11: transcriptional mechanisms based on canonical WNT signals and GATA transcription factors signaling. | ||||||||||
| Author: | Katoh, Masuko|Katoh, Masaru | ||||||||||
| PMID: | 19578797 | ||||||||||
| 7. | |||||||||||
| Journal: | PLoS One. 2012;7(5):e37137. | ||||||||||
| Title: | LGR6 is a high affinity receptor of R-spondins and potentially functions as a tumor suppressor. | ||||||||||
| Author: | Gong, Xing|Carmon, Kendra S|Lin, Qiushi|Thomas, Anthony|Yi, Jing|Liu, Qingyun | ||||||||||
| PMID: | 22615920 | ||||||||||
| 8. | |||||||||||
| Journal: | Cell Signal. 2013 Jan;25(1):178-89. | ||||||||||
| Title: | Cripto-1 enhances the canonical Wnt/beta-catenin signaling pathway by binding to LRP5 and LRP6 co-receptors. | ||||||||||
| Author: | Nagaoka, Tadahiro|Karasawa, Hideaki|Turbyville, Thomas|Rangel, Maria-Cristina|Castro, Nadia P|Gonzales, Monica|Baker, Alyson|Seno, Masaharu|Lockett, Stephen|Greer, Yoshimi E|Rubin, Jeffrey S|Salomon, David S|Bianco, Caterina | ||||||||||
| PMID: | 23022962 | ||||||||||
| 9. | |||||||||||
| Journal: | Int J Oncol. 2014 Jan;44(1):211-21. | ||||||||||
| Title: | Comprehensive genomic analyses of a metastatic colon cancer to the lung by whole exome sequencing and gene expression analysis. | ||||||||||
| Author: | Fang, Li Tai|Lee, Sharon|Choi, Helen|Kim, Hong Kwan|Jew, Gregory|Kang, Hio Chung|Chen, Lin|Jablons, David|Kim, Il-Jin | ||||||||||
| PMID: | 24172857 | ||||||||||
| 10. | |||||||||||
| Journal: | Mol Cell Oncol. 2015 Jan 23;2(3):e995046. | ||||||||||
| Title: | CD44 regulates Wnt signaling at the level of LRP6. | ||||||||||
| Author: | Orian-Rousseau, Veronique|Schmitt, Mark | ||||||||||
| PMID: | 27308483 | ||||||||||
| 11. | |||||||||||
| Journal: | Mol Cancer Res. 2015 Nov;13(11):1509-19. | ||||||||||
| Title: | Calcipotriol Targets LRP6 to Inhibit Wnt Signaling in Pancreatic Cancer. | ||||||||||
| Author: | Arensman, Michael D|Nguyen, Phillip|Kershaw, Kathleen M|Lay, Anna R|Ostertag-Hill, Claire A|Sherman, Mara H|Downes, Michael|Liddle, Christopher|Evans, Ronald M|Dawson, David W | ||||||||||
| PMID: | 26224368 | ||||||||||
| 12. | |||||||||||
| Journal: | Cell Stem Cell. 2015 Jul 2;17(1):47-59. | ||||||||||
| Title: | TPO-Induced Metabolic Reprogramming Drives Liver Metastasis of Colorectal Cancer CD110+ Tumor-Initiating Cells. | ||||||||||
| Author: | Wu, ZhengMing|Wei, Dong|Gao, WenChao|Xu, YuTing|Hu, ZhiQian|Ma, ZhenYu|Gao, ChunFang|Zhu, XiaoYan|Li, QingQuan | ||||||||||
| PMID: | 26140605 | ||||||||||
| 13. | |||||||||||
| Journal: | Oncogene. 2015 Sep 17;34(38):4914-27. | ||||||||||
| Title: | Oncogenic KRAS signalling promotes the Wnt/beta-catenin pathway through LRP6 in colorectal cancer. | ||||||||||
| Author: | Lemieux, E|Cagnol, S|Beaudry, K|Carrier, J|Rivard, N | ||||||||||
| PMID: | 25500543 | ||||||||||
| 14. | |||||||||||
| Journal: | Cell Death Differ. 2015 Apr;22(4):677-89. | ||||||||||
| Title: | CD44 functions in Wnt signaling by regulating LRP6 localization and activation. | ||||||||||
| Author: | Schmitt, M|Metzger, M|Gradl, D|Davidson, G|Orian-Rousseau, V | ||||||||||
| PMID: | 25301071 | ||||||||||
| 15. | |||||||||||
| Journal: | Int J Cancer. 2015 Oct 1;137(7):1560-73. | ||||||||||
| Title: | Sialidase NEU3 contributes neoplastic potential on colon cancer cells as a key modulator of gangliosides by regulating Wnt signaling. | ||||||||||
| Author: | Takahashi, Kohta|Hosono, Masahiro|Sato, Ikuro|Hata, Keiko|Wada, Tadashi|Yamaguchi, Kazunori|Nitta, Kazuo|Shima, Hiroshi|Miyagi, Taeko | ||||||||||
| PMID: | 25810027 | ||||||||||
| 16. | |||||||||||
| Journal: | PLoS Genet. 2016 Feb 22;12(2):e1005880. | ||||||||||
| Title: | Identification of Novel Candidate Genes for Early-Onset Colorectal Cancer Susceptibility. | ||||||||||
| Author: | de Voer, Richarda M|Hahn, Marc-Manuel|Weren, Robbert D A|Mensenkamp, Arjen R|Gilissen, Christian|van Zelst-Stams, Wendy A|Spruijt, Liesbeth|Kets, C Marleen|Zhang, Junxiao|Venselaar, Hanka|Vreede, Lilian|Schubert, Nil|Tychon, Marloes|Derks, Ronny|Schackert | ||||||||||
| PMID: | 26901136 | ||||||||||
| 17. | |||||||||||
| Journal: | Curr Top Med Chem. 2016;16(25):2765-78. | ||||||||||
| Title: | Clients and Oncogenic Roles of Molecular Chaperone gp96/grp94. | ||||||||||
| Author: | Ansa-Addo, Ephraim A|Thaxton, Jessica|Hong, Feng|Wu, Bill X|Zhang, Yongliang|Fugle, Caroline W|Metelli, Alessandra|Riesenberg, Brian|Williams, Katelyn|Gewirth, Daniel T|Chiosis, Gabriela|Liu, Bei|Li, Zihai | ||||||||||
| PMID: | 27072698 | ||||||||||
| 18. | |||||||||||
| Journal: | Mol Cancer Res. 2016 Sep;14(9):859-68. | ||||||||||
| Title: | Novel Bispecific Domain Antibody to LRP6 Inhibits Wnt and R-spondin Ligand-Induced Wnt Signaling and Tumor Growth. | ||||||||||
| Author: | Jackson, Heather|Granger, David|Jones, Gavin|Anderson, Louisa|Friel, Sarah|Rycroft, Daniel|Fieles, William|Tunstead, James|Steward, Michael|Wattam, Trevor|Walker, Adam|Griggs, Jeremy|Al-Hajj, Muhammad|Shelton, Christopher | ||||||||||
| PMID: | 27401612 | ||||||||||
| 19. | |||||||||||
| Journal: | Cancer Biomark. 2017;19(2):151-159. | ||||||||||
| Title: | Pattern of LRP6 gene expression in tumoral tissues of colorectal cancer. | ||||||||||
| Author: | Rismani, Elham|Fazeli, Mohammad Sadegh|Mahmoodzadeh, Habibollah|Movassagh, Aghdas|Azami, Sina|Karimipoor, Morteza|Teimoori-Toolabi, Ladan | ||||||||||
| PMID: | 28387660 | ||||||||||
| 20. | |||||||||||
| Journal: | Oncotarget. 2017 Dec 4;8(67):111597-111607. | ||||||||||
| Title: | LRP6 targeting suppresses gastric tumorigenesis via P14(ARF)-Mdm2-P53-dependent cellular senescence. | ||||||||||
| Author: | Wang, Haibin|Xu, Guoxing|Huang, Zhengjie|Li, Weizheng|Cai, Huali|Zhang, Yunda|Xiong, Disheng|Liu, Gang|Wang, Shengjie|Xue, Zengfu|Luo, Qi | ||||||||||
| PMID: | 29340077 | ||||||||||
| 21. | |||||||||||
| Journal: | Oncotarget. 2017 Nov 30;8(65):109632-109645. | ||||||||||
| Title: | LRP6 promotes invasion and metastasis of colorectal cancer through cytoskeleton dynamics. | ||||||||||
| Author: | Yao, Qian|An, Yu|Hou, Wei|Cao, Ya-Nan|Yao, Meng-Fei|Ma, Ning-Ning|Hou, Lin|Zhang, Hong|Liu, Hai-Jing|Zhang, Bo | ||||||||||
| PMID: | 29312635 | ||||||||||
| 22. | |||||||||||
| Journal: | J BUON. 2017 Sep-Oct;22(5):1107-1114. | ||||||||||
| Title: | Gene expression profiling demonstrates WNT/beta-catenin pathway genes alteration in Mexican patients with colorectal cancer and diabetes mellitus. | ||||||||||
| Author: | Ivonne Wence-Chavez, Laura|Palomares-Chacon, Ulises|Pablo Flores-Gutierrez, Juan|Felipe Jave-Suarez, Luis|Del Carmen Aguilar-Lemarroy, Adriana|Barros-Nunez, Patricio|Esperanza Flores-Martinez, Silvia|Sanchez-Corona, Jose|Alejandra Rosales-Reynoso, Monica | ||||||||||
| PMID: | 29135090 | ||||||||||
| 23. | |||||||||||
| Journal: | Oncotarget. 2017 Jul 11;8(28):46191-46203. | ||||||||||
| Title: | Hypermethylation of NDN promotes cell proliferation by activating the Wnt signaling pathway in colorectal cancer. | ||||||||||
| Author: | Hu, Yu-Han|Chen, Qing|Lu, Yan-Xia|Zhang, Jian-Ming|Lin, Chun|Zhang, Fan|Zhang, Wen-Juan|Li, Xiao-Min|Zhang, Wei|Li, Xue-Nong | ||||||||||
| PMID: | 28521288 | ||||||||||
| 24. | |||||||||||
| Journal: | Int J Oncol. 2017 Feb;50(2):487-496. | ||||||||||
| Title: | Identification of microRNA-487b as a negative regulator of liver metastasis by regulation of KRAS in colorectal cancer. | ||||||||||
| Author: | Hata, Tsuyoshi|Mokutani, Yukako|Takahashi, Hidekazu|Inoue, Akira|Munakata, Koji|Nagata, Kazuya|Haraguchi, Naotsugu|Nishimura, Junichi|Hata, Taishi|Matsuda, Chu|Murata, Kohei|Mizushima, Tsunekazu|Doki, Yuichiro|Mori, Masaki|Yamamoto, Hirofumi | ||||||||||
| PMID: | 28000854 | ||||||||||
| 25. | |||||||||||
| Journal: | Gastroenterology. 2017 Jan;152(1):75-77.e4. | ||||||||||
| Title: | Validation of Recently Proposed Colorectal Cancer Susceptibility Gene Variants in an Analysis of Families and Patients-a Systematic Review. | ||||||||||
| Author: | Broderick, Peter|Dobbins, Sara E|Chubb, Daniel|Kinnersley, Ben|Dunlop, Malcolm G|Tomlinson, Ian|Houlston, Richard S | ||||||||||
| PMID: | 27713038 | ||||||||||
| 26. | |||||||||||
| Journal: | PLoS Genet. 2018 Feb 6;14(2):e1007178. | ||||||||||
| Title: | Axin phosphorylation in both Wnt-off and Wnt-on states requires the tumor suppressor APC. | ||||||||||
| Author: | Tacchelly-Benites, Ofelia|Wang, Zhenghan|Yang, Eungi|Benchabane, Hassina|Tian, Ai|Randall, Michael P|Ahmed, Yashi | ||||||||||
| PMID: | 29408853 | ||||||||||
| 27. | |||||||||||
| Journal: | Nat Med. 2018 Mar;24(3):262-270. | ||||||||||
| Title: | DKK2 imparts tumor immunity evasion through beta-catenin-independent suppression of cytotoxic immune-cell activation. | ||||||||||
| Author: | Xiao, Qian|Wu, Jibo|Wang, Wei-Jia|Chen, Shiyang|Zheng, Yingxia|Yu, Xiaoqing|Meeth, Katrina|Sahraei, Mahnaz|Bothwell, Alfred L M|Chen, Lieping|Bosenberg, Marcus|Chen, Jianfeng|Sexl, Veronika|Sun, Le|Li, Lin|Tang, Wenwen|Wu, Dianqing | ||||||||||
| PMID: | 29431745 | ||||||||||
| 28. | |||||||||||
| Journal: | Life Sci. 2018 Aug 15;207:532-549. | ||||||||||
| Title: | Raddeanin A inhibits growth and induces apoptosis in human colorectal cancer through downregulating the Wnt/beta-catenin and NF-kappaB signaling pathway. | ||||||||||
| Author: | Wang, Yu|Bao, Xiaowen|Zhao, Ang|Zhang, Jie|Zhang, Mingya|Zhang, Qi|Ma, Bo | ||||||||||
| PMID: | 29972765 | ||||||||||
| 29. | |||||||||||
| Journal: | J Biomol Struct Dyn. 2018 Jul 23:1-46. | ||||||||||
| Title: | In Silico studying of the whole protein structure and dynamics of Dickkopf family members showed that N terminal domain of Dickkopf 2 in contrary to other Dickkopfs facilitates its interaction with Low Density Lipoprotein Receptor Related Protein 5/6. | ||||||||||
| Author: | Sadeghi, Solmaz|Poorebrahim, Mansour|Rahimi, Hamzeh|Karimipoor, Morteza|Azadmanesh, Kayhan|Khorramizadeh, Mohammad Reza|Teimoori-Toolabi, Ladan | ||||||||||
| PMID: | 30035709 | ||||||||||