Primary Site >> Colorectal Cancer

Gene >> LRP5

Journal: J Neurosci. 2003 May 1;23(9):3735-44.
Title: Netrin-1 is a chemorepellent for oligodendrocyte precursor cells in the embryonic spinal cord.
Author: Jarjour, Andrew A|Manitt, Colleen|Moore, Simon W|Thompson, Katherine M|Yuh, Sung-Joo|Kennedy, Timothy E
PMID: 12736344
Journal: Curr Cancer Drug Targets. 2004 Dec;4(8):653-71.
Title: Wnt/beta-catenin signaling pathway as a novel cancer drug target.
Author: Luu, Hue H|Zhang, Ruiwen|Haydon, Rex C|Rayburn, Elizabeth|Kang, Quan|Si, Weike|Park, Jong Kyung|Wang, Hui|Peng, Ying|Jiang, Wei|He, Tong-Chuan
PMID: 15578921
Journal: Oncogene. 2005 Feb 3;24(6):1098-103.
Title: The Wnt antagonist DICKKOPF-1 gene is a downstream target of beta-catenin/TCF and is downregulated in human colon cancer.
Author: Gonzalez-Sancho, Jose Manuel|Aguilera, Oscar|Garcia, Jose Miguel|Pendas-Franco, Natalia|Pena, Cristina|Cal, Santiago|Garcia de Herreros, Antonio|Bonilla, Felix|Munoz, Alberto
PMID: 15592505
Journal: Sci STKE. 2005 Feb 15;2005(271):cm1.
Title: Wnt/beta-catenin pathway.
Author: Moon, Randall T
PMID: 15713948
Journal: BMC Genomics. 2006 Jun 13;7:148.
Title: Verification of predicted alternatively spliced Wnt genes reveals two new splice variants (CTNNB1 and LRP5) and altered Axin-1 expression during tumour progression.
Author: Pospisil, Heike|Herrmann, Alexander|Butherus, Kristine|Pirson, Stefan|Reich, Jens G|Kemmner, Wolfgang
PMID: 16772034
Journal: Clin Cancer Res. 2007 Jan 15;13(2 Pt 1):415-20.
Title: Gene expression signature and the prediction of ulcerative colitis-associated colorectal cancer by DNA microarray.
Author: Watanabe, Toshiaki|Kobunai, Takashi|Toda, Etsuko|Kanazawa, Takamitsu|Kazama, Yoshihiro|Tanaka, Junichiro|Tanaka, Toshiaki|Yamamoto, Yoko|Hata, Keisuke|Kojima, Tetsu|Yokoyama, Tadashi|Konishi, Tsuyoshi|Okayama, Yoshihiro|Sugimoto, Yoshikazu|Oka, Toshinori|
PMID: 17255260
Journal: Int J Mol Med. 2007 Mar;19(3):529-33.
Title: Comparative integromics on FZD7 orthologs: conserved binding sites for PU.1, SP1, CCAAT-box and TCF/LEF/SOX transcription factors within 5'-promoter region of mammalian FZD7 orthologs.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 17273804
Journal: BMC Cell Biol. 2007 Mar 26;8:12.
Title: Regulation of norrin receptor frizzled-4 by Wnt2 in colon-derived cells.
Author: Planutis, Kestutis|Planutiene, Marina|Moyer, Mary Pat|Nguyen, Anthony V|Perez, Cherlyn A|Holcombe, Randall F
PMID: 17386109
Journal: J Bone Miner Res. 2007 Dec;22 Suppl 2:V2-10.
Title: Vitamin D receptor: key roles in bone mineral pathophysiology, molecular mechanism of action, and novel nutritional ligands.
Author: Jurutka, Peter W|Bartik, Leonid|Whitfield, G Kerr|Mathern, Douglas R|Barthel, Thomas K|Gurevich, Miriam|Hsieh, Jui-Cheng|Kaczmarska, Magdalena|Haussler, Carol A|Haussler, Mark R
PMID: 18290715
Journal: J Steroid Biochem Mol Biol. 2010 Jul;121(1-2):88-97.
Title: The nuclear vitamin D receptor controls the expression of genes encoding factors which feed the "Fountain of Youth" to mediate healthful aging.
Author: Haussler, Mark R|Haussler, Carol A|Whitfield, G Kerr|Hsieh, Jui-Cheng|Thompson, Paul D|Barthel, Thomas K|Bartik, Leonid|Egan, Jan B|Wu, Yifei|Kubicek, Jana L|Lowmiller, Christine L|Moffet, Eric W|Forster, Ryan E|Jurutka, Peter W
PMID: 20227497
Journal: Cell Signal. 2013 Jan;25(1):178-89.
Title: Cripto-1 enhances the canonical Wnt/beta-catenin signaling pathway by binding to LRP5 and LRP6 co-receptors.
Author: Nagaoka, Tadahiro|Karasawa, Hideaki|Turbyville, Thomas|Rangel, Maria-Cristina|Castro, Nadia P|Gonzales, Monica|Baker, Alyson|Seno, Masaharu|Lockett, Stephen|Greer, Yoshimi E|Rubin, Jeffrey S|Salomon, David S|Bianco, Caterina
PMID: 23022962
Journal: Mol Hum Reprod. 2013 Feb;19(2):57-71.
Title: Oncogenic Wnt/beta-catenin signalling pathways in the cancer-resistant epididymis have implications for cancer research.
Author: Wang, K|Li, N|Yeung, C H|Li, J Y|Wang, H Y|Cooper, T G
PMID: 23155044
Journal: Epigenomics. 2014 Apr;6(2):179-91.
Title: DNA methylation changes in genes frequently mutated in sporadic colorectal cancer and in the DNA repair and Wnt/beta-catenin signaling pathway genes.
Author: Farkas, Sanja A|Vymetalkova, Veronika|Vodickova, Ludmila|Vodicka, Pavel|Nilsson, Torbjorn K
PMID: 24811787
Journal: PLoS Genet. 2016 Feb 22;12(2):e1005880.
Title: Identification of Novel Candidate Genes for Early-Onset Colorectal Cancer Susceptibility.
Author: de Voer, Richarda M|Hahn, Marc-Manuel|Weren, Robbert D A|Mensenkamp, Arjen R|Gilissen, Christian|van Zelst-Stams, Wendy A|Spruijt, Liesbeth|Kets, C Marleen|Zhang, Junxiao|Venselaar, Hanka|Vreede, Lilian|Schubert, Nil|Tychon, Marloes|Derks, Ronny|Schackert
PMID: 26901136
Journal: PLoS One. 2016 Jun 3;11(6):e0156788.
Title: Procaine Inhibits Osteo/Odontogenesis through Wnt/beta-Catenin Inactivation.
Author: Herencia, Carmen|Diaz-Tocados, Juan Miguel|Jurado, Lidia|Montes de Oca, Addy|Rodriguez-Ortiz, Maria Encarnacion|Martin-Alonso, Carmen|Martinez-Moreno, Julio M|Vergara, Noemi|Rodriguez, Mariano|Almaden, Yolanda|Munoz-Castaneda, Juan R
PMID: 27257912
Journal: Biomed Pharmacother. 2017 Mar;87:102-109.
Title: Taspine derivative 12k suppressed A549 cell migration through the Wnt/beta-catenin and EphrinB2 signaling pathway.
Author: Dai, Bingling|Ma, Yujiao|Yang, Tianfeng|Wang, Wenjie|Zhang, Yanmin
PMID: 28049091
Journal: Oncotarget. 2017 Mar 21;8(12):20025-20041.
Title: Tissue transglutaminase induces Epithelial-Mesenchymal-Transition and the acquisition of stem cell like characteristics in colorectal cancer cells.
Author: Ayinde, Oluseyi|Wang, Zhuo|Griffin, Martin
PMID: 28223538
Journal: Int J Mol Med. 2017 Sep;40(3):587-606.
Title: Molecular genetics and targeted therapy of WNT-related human diseases (Review).
Author: Katoh, Masuko|Katoh, Masaru
PMID: 28731148
Journal: Nat Med. 2018 Mar;24(3):262-270.
Title: DKK2 imparts tumor immunity evasion through beta-catenin-independent suppression of cytotoxic immune-cell activation.
Author: Xiao, Qian|Wu, Jibo|Wang, Wei-Jia|Chen, Shiyang|Zheng, Yingxia|Yu, Xiaoqing|Meeth, Katrina|Sahraei, Mahnaz|Bothwell, Alfred L M|Chen, Lieping|Bosenberg, Marcus|Chen, Jianfeng|Sexl, Veronika|Sun, Le|Li, Lin|Tang, Wenwen|Wu, Dianqing
PMID: 29431745
Journal: J Biomol Struct Dyn. 2018 Jul 23:1-46.
Title: In Silico studying of the whole protein structure and dynamics of Dickkopf family members showed that N terminal domain of Dickkopf 2 in contrary to other Dickkopfs facilitates its interaction with Low Density Lipoprotein Receptor Related Protein 5/6.
Author: Sadeghi, Solmaz|Poorebrahim, Mansour|Rahimi, Hamzeh|Karimipoor, Morteza|Azadmanesh, Kayhan|Khorramizadeh, Mohammad Reza|Teimoori-Toolabi, Ladan
PMID: 30035709
Journal: Phytomedicine. 2018 Jul 15;46:85-92.
Title: Wnt/beta-catenin signaling pathway is involved in regulating the migration by an effective natural compound brucine in LoVo cells.
Author: Shi, Xianpeng|Zhu, Man|Kang, Yuan|Yang, Tianfeng|Chen, Xia|Zhang, Yanmin
PMID: 30097126