Primary Site >> Colorectal Cancer
Gene >> LRP5
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Ref: Netrin-1 is a chemorepellent for oligodendrocyte precursor cells in the embryonic spinal cord. PMID: 12736344 |
Ref: Wnt/beta-catenin signaling pathway as a novel cancer drug target. PMID: 15578921 |
Ref: The Wnt antagonist DICKKOPF-1 gene is a downstream target of beta-catenin/TCF and is downregulated in human colon cancer. PMID: 15592505 Ref: Wnt/beta-catenin pathway. PMID: 15713948 |
Ref: Verification of predicted alternatively spliced Wnt genes reveals two new splice variants (CTNNB1 and LRP5) and altered Axin-1 expression during tumour progression. PMID: 16772034 |
Ref: Gene expression signature and the prediction of ulcerative colitis-associated colorectal cancer by DNA microarray. PMID: 17255260 Ref: Comparative integromics on FZD7 orthologs: conserved binding sites for PU.1, SP1, CCAAT-box and TCF/LEF/SOX transcription factors within 5'-promoter region of mammalian FZD7 orthologs. PMID: 17273804 Ref: Regulation of norrin receptor frizzled-4 by Wnt2 in colon-derived cells. PMID: 17386109 Ref: Vitamin D receptor: key roles in bone mineral pathophysiology, molecular mechanism of action, and novel nutritional ligands. PMID: 18290715 |
Ref: The nuclear vitamin D receptor controls the expression of genes encoding factors which feed the "Fountain of Youth" to mediate healthful aging. PMID: 20227497 |
Ref: Cripto-1 enhances the canonical Wnt/beta-catenin signaling pathway by binding to LRP5 and LRP6 co-receptors. PMID: 23022962 Ref: Oncogenic Wnt/beta-catenin signalling pathways in the cancer-resistant epididymis have implications for cancer research. PMID: 23155044 |
Ref: DNA methylation changes in genes frequently mutated in sporadic colorectal cancer and in the DNA repair and Wnt/beta-catenin signaling pathway genes. PMID: 24811787 |
Ref: Identification of Novel Candidate Genes for Early-Onset Colorectal Cancer Susceptibility. PMID: 26901136 Ref: Procaine Inhibits Osteo/Odontogenesis through Wnt/beta-Catenin Inactivation. PMID: 27257912 |
Ref: Taspine derivative 12k suppressed A549 cell migration through the Wnt/beta-catenin and EphrinB2 signaling pathway. PMID: 28049091 Ref: Tissue transglutaminase induces Epithelial-Mesenchymal-Transition and the acquisition of stem cell like characteristics in colorectal cancer cells. PMID: 28223538 Ref: Molecular genetics and targeted therapy of WNT-related human diseases (Review). PMID: 28731148 |
Ref: DKK2 imparts tumor immunity evasion through beta-catenin-independent suppression of cytotoxic immune-cell activation. PMID: 29431745 Ref: In Silico studying of the whole protein structure and dynamics of Dickkopf family members showed that N terminal domain of Dickkopf 2 in contrary to other Dickkopfs facilitates its interaction with Low Density Lipoprotein Receptor Related Protein 5/6. PMID: 30035709 Ref: Wnt/beta-catenin signaling pathway is involved in regulating the migration by an effective natural compound brucine in LoVo cells. PMID: 30097126 |