Primary Site >> Colorectal Cancer

Gene >> LPAR2

Journal: Cancer Res. 2003 Apr 1;63(7):1706-11.
Title: Lysophosphatidic acid (LPA) enhances the metastatic potential of human colon carcinoma DLD1 cells through LPA1.
Author: Shida, Dai|Kitayama, Joji|Yamaguchi, Hironori|Okaji, Yurai|Tsuno, Nelson Hirokazu|Watanabe, Toshiaki|Takuwa, Yoh|Nagawa, Hirokazu
PMID: 12670925
Journal: Lab Invest. 2004 Oct;84(10):1352-62.
Title: Aberrant expression of lysophosphatidic acid (LPA) receptors in human colorectal cancer.
Author: Shida, Dai|Watanabe, Toshiaki|Aoki, Junken|Hama, Kotaro|Kitayama, Joji|Sonoda, Hirofumi|Kishi, Yasuhiro|Yamaguchi, Hironori|Sasaki, Shin|Sako, Akihiro|Konishi, Tsuyoshi|Arai, Hiroyuki|Nagawa, Hirokazu
PMID: 15220934
Journal: Am J Physiol Cell Physiol. 2005 Jul;289(1):C2-11. Epub 2005 Feb 23.
Title: LPA2 receptor mediates mitogenic signals in human colon cancer cells.
Author: Yun, C Chris|Sun, Hong|Wang, Dongsheng|Rusovici, Raluca|Castleberry, Amanda|Hall, Randy A|Shim, Hyunsuk
PMID: 15728708
Journal: ChemMedChem. 2007 Dec;2(12):1789-98.
Title: Alkoxymethylenephosphonate analogues of (Lyso) phosphatidic acid stimulate signaling networks coupled to the LPA2 receptor.
Author: Gajewiak, Joanna|Tsukahara, Ryoko|Tsukahara, Tamotsu|Fujiwara, Yuko|Yu, Shuanxing|Lu, Yiling|Murph, Mandi|Mills, Gordon B|Tigyi, Gabor|Prestwich, Glenn D
PMID: 17952880
Journal: Exp Cell Res. 2008 Feb 1;314(3):530-42. Epub 2007 Nov 12.
Title: Autotaxin and lysophosphatidic acid stimulate intestinal cell motility by redistribution of the actin modifying protein villin to the developing lamellipodia.
Author: Khurana, Seema|Tomar, Alok|George, Sudeep P|Wang, Yaohong|Siddiqui, Mohammad Rizwan|Guo, Huazhang|Tigyi, Gabor|Mathew, Sijo
PMID: 18054784
Journal: Gastroenterology. 2009 May;136(5):1711-20.
Title: The absence of LPA2 attenuates tumor formation in an experimental model of colitis-associated cancer.
Author: Lin, Songbai|Wang, Dongsheng|Iyer, Smita|Ghaleb, Amr M|Shim, Hyunsuk|Yang, Vincent W|Chun, Jerold|Yun, C Chris
PMID: 19328876
Journal: Prog Lipid Res. 2010 Oct;49(4):335-42.
Title: LPA(3), a unique G protein-coupled receptor for lysophosphatidic acid.
Author: Hama, Kotaro|Aoki, Junken
PMID: 20230855
Journal: Am J Physiol Gastrointest Liver Physiol. 2010 Nov;299(5):G1128-38.
Title: The absence of LPA receptor 2 reduces the tumorigenesis by ApcMin mutation in the intestine.
Author: Lin, Songbai|Lee, Sei-Jung|Shim, Hyunsuk|Chun, Jerold|Yun, C Chris
PMID: 20724530
Journal: Virchows Arch. 2010 Dec;457(6):669-76.
Title: Differential expressions and DNA methylation patterns of lysophosphatidic acid receptor genes in human colon cancer cells.
Author: Tsujino, Megumu|Fujii, Minako|Okabe, Kyoko|Mori, Toshio|Fukushima, Nobuyuki|Tsujiuchi, Toshifumi
PMID: 20890765
Journal: Gastroenterology. 2011 Mar;140(3):924-34.
Title: MAGI-3 competes with NHERF-2 to negatively regulate LPA2 receptor signaling in colon cancer cells.
Author: Lee, Sei-Jung|Ritter, Stefanie L|Zhang, Huanchun|Shim, Hyunsuk|Hall, Randy A|Yun, C Chris
PMID: 21134377
Journal: PLoS One. 2015 Sep 9;10(9):e0137513.
Title: HIF1alpha-Induced by Lysophosphatidic Acid Is Stabilized via Interaction with MIF and CSN5.
Author: No, Yi Ran|Lee, Sei-Jung|Kumar, Ajay|Yun, C Chris
PMID: 26352431
Journal: Am J Physiol Gastrointest Liver Physiol. 2016 Apr 15;310(8):G586-98.
Title: Deletion of Na+/H+ exchanger regulatory factor 2 represses colon cancer progress by suppression of Stat3 and CD24.
Author: Yoshida, Michihiro|Zhao, Luqing|Grigoryan, Gevorg|Shim, Hyunsuk|He, Peijian|Yun, C Chris
PMID: 26867566
Journal: World J Gastroenterol. 2016 Feb 28;22(8):2503-11.
Title: Sphingosine kinase 1 is upregulated with lysophosphatidic acid receptor 2 in human colorectal cancer.
Author: Shida, Dai|Inoue, Satoru|Yoshida, Yuki|Kodaka, Atsushi|Tsuji, Tsutomu|Tsuiji, Makoto
PMID: 26937138
Journal: PLoS One. 2016 Apr 28;11(4):e0154527.
Title: Transgenic Expression of Human Lysophosphatidic Acid Receptor LPA2 in Mouse Intestinal Epithelial Cells Induces Intestinal Dysplasia.
Author: Yoshida, Michihiro|He, Peijian|Yun, C Chris
PMID: 27124742