Primary Site >> Colorectal Cancer

Gene >> LPAR2

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Ref: Lysophosphatidic acid (LPA) enhances the metastatic potential of human colon carcinoma DLD1 cells through LPA1.
PMID: 12670925
Ref: Aberrant expression of lysophosphatidic acid (LPA) receptors in human colorectal cancer.
PMID: 15220934
Ref: LPA2 receptor mediates mitogenic signals in human colon cancer cells.
PMID: 15728708
Ref: Alkoxymethylenephosphonate analogues of (Lyso) phosphatidic acid stimulate signaling networks coupled to the LPA2 receptor.
PMID: 17952880
Ref: Autotaxin and lysophosphatidic acid stimulate intestinal cell motility by redistribution of the actin modifying protein villin to the developing lamellipodia.
PMID: 18054784
Ref: The absence of LPA2 attenuates tumor formation in an experimental model of colitis-associated cancer.
PMID: 19328876
Ref: LPA(3), a unique G protein-coupled receptor for lysophosphatidic acid.
PMID: 20230855
Ref: The absence of LPA receptor 2 reduces the tumorigenesis by ApcMin mutation in the intestine.
PMID: 20724530
Ref: Differential expressions and DNA methylation patterns of lysophosphatidic acid receptor genes in human colon cancer cells.
PMID: 20890765
Ref: MAGI-3 competes with NHERF-2 to negatively regulate LPA2 receptor signaling in colon cancer cells.
PMID: 21134377
Ref: HIF1alpha-Induced by Lysophosphatidic Acid Is Stabilized via Interaction with MIF and CSN5.
PMID: 26352431
Ref: Deletion of Na+/H+ exchanger regulatory factor 2 represses colon cancer progress by suppression of Stat3 and CD24.
PMID: 26867566
Ref: Sphingosine kinase 1 is upregulated with lysophosphatidic acid receptor 2 in human colorectal cancer.
PMID: 26937138
Ref: Transgenic Expression of Human Lysophosphatidic Acid Receptor LPA2 in Mouse Intestinal Epithelial Cells Induces Intestinal Dysplasia.
PMID: 27124742