Primary Site >> Stomach Cancer

Gene >> LOX

Journal: Ai Zheng. 2002 Jun;21(6):671-4.
Title: [Expression of lysyl oxidase gene in upper digestive tract carcinomas and its clinical significance].
Author: He, Jie|Tang, Huai-jing|Wang, Yue-ying|Xiong, Mei-hua|Zhou, Fang|Shao, Kang|Li, Ti-ping
PMID: 12452073
Journal: Cancer Res. 2002 Nov 15;62(22):6645-50.
Title: Identification of silencing of nine genes in human gastric cancers.
Author: Kaneda, Atsushi|Kaminishi, Michio|Yanagihara, Kazuyoshi|Sugimura, Takashi|Ushijima, Toshikazu
PMID: 12438262
Journal: J Gastroenterol Hepatol. 2004 Jan;19(1):31-7.
Title: Five-lipoxygenase-activating protein inhibitor MK-886 induces apoptosis in gastric cancer through upregulation of p27kip1 and bax.
Author: Fan, Xiao Ming|Tu, Shui Ping|Lam, Shiu Kum|Wang, Wei Ping|Wu, Jing|Wong, Wai Man|Yuen, Man Fung|Lin, Marie Chia Mi|Kung, Hsiange Fu|Wong, Benjamin Chun-Yu
PMID: 14675240
Journal: Cancer Res. 2004 Sep 15;64(18):6410-5.
Title: Lysyl oxidase is a tumor suppressor gene inactivated by methylation and loss of heterozygosity in human gastric cancers.
Author: Kaneda, Atsushi|Wakazono, Kuniko|Tsukamoto, Tetsuya|Watanabe, Naoko|Yagi, Yukiko|Tatematsu, Masae|Kaminishi, Michio|Sugimura, Takashi|Ushijima, Toshikazu
PMID: 15374948
Journal: Clin Cancer Res. 2006 Feb 1;12(3 Pt 1):989-95.
Title: High levels of aberrant DNA methylation in Helicobacter pylori-infected gastric mucosae and its possible association with gastric cancer risk.
Author: Maekita, Takao|Nakazawa, Kazuyuki|Mihara, Mami|Nakajima, Takeshi|Yanaoka, Kimihiko|Iguchi, Mikitaka|Arii, Kenji|Kaneda, Atsushi|Tsukamoto, Tetsuya|Tatematsu, Masae|Tamura, Gen|Saito, Daizo|Sugimura, Takashi|Ichinose, Masao|Ushijima, Toshikazu
PMID: 16467114
Journal: Cancer. 2006 Mar 15;106(6):1250-9.
Title: Accumulation of DNA methylation is associated with tumor stage in gastric cancer.
Author: Oue, Naohide|Mitani, Yoshitsugu|Motoshita, Junichi|Matsumura, Shunji|Yoshida, Kazuhiro|Kuniyasu, Hiroki|Nakayama, Hirofumi|Yasui, Wataru
PMID: 16475210
Journal: Clin Cancer Res. 2006 May 15;12(10):2995-3002.
Title: CpG island methylation status in gastric carcinoma with and without infection of Epstein-Barr virus.
Author: Chang, Moon-Sung|Uozaki, Hiroshi|Chong, Ja-Mun|Ushiku, Tetsuo|Sakuma, Kazuya|Ishikawa, Shunpei|Hino, Rumi|Barua, Rita Rani|Iwasaki, Yoshiaki|Arai, Kuniyoshi|Fujii, Hideki|Nagai, Hideo|Fukayama, Masashi
PMID: 16707594
Journal: Cancer Sci. 2006 Nov;97(11):1155-8. Epub 2006 Sep 5.
Title: Multiple tumor suppressor genes are increasingly methylated with age in non-neoplastic gastric epithelia.
Author: So, Kanji|Tamura, Gen|Honda, Teiichiro|Homma, Naoyuki|Waki, Takayoshi|Togawa, Naoyuki|Nishizuka, Satoshi|Motoyama, Teiichi
PMID: 16952303
Journal: Clin Cancer Res. 2007 Sep 1;13(17):5095-102.
Title: Methylation of tumor-related genes in neoadjuvant-treated gastric cancer: relation to therapy response and clinicopathologic and molecular features.
Author: Napieralski, Rudolf|Ott, Katja|Kremer, Markus|Becker, Karen|Boulesteix, Anne-Laure|Lordick, Florian|Siewert, Jorg Rudiger|Hofler, Heinz|Keller, Gisela
PMID: 17785563
Journal: Cancer Lett. 2008 Nov 8;270(2):218-28.
Title: The long-term effect of Helicobacter pylori eradication on COX-1/2, 5-LOX and leukotriene receptors in patients with a risk gastritis phenotype--a link to gastric carcinogenesis.
Author: Venerito, Marino|Kuester, Doerthe|Wex, Thomas|Roessner, Albert|Malfertheiner, Peter|Treiber, Gerhard
PMID: 18571838
Journal: Oncol Rep. 2009 May;21(5):1251-9.
Title: Comparative analysis of DNA methylation between primary and metastatic gastric carcinoma.
Author: Kim, Ji Hun|Jung, Eun Ji|Lee, Hye Seung|Kim, Min A|Kim, Woo Ho
PMID: 19360301
Journal: Cancer Res. 2009 Aug 15;69(16):6685-93.
Title: A loss-of-function polymorphism in the propeptide domain of the LOX gene and breast cancer.
Author: Min, Chengyin|Yu, Ziyang|Kirsch, Kathrin H|Zhao, Yingshe|Vora, Siddharth R|Trackman, Philip C|Spicer, Douglas B|Rosenberg, Lynn|Palmer, Julie R|Sonenshein, Gail E
PMID: 19654310
Journal: Cancer Sci. 2010 Jun;101(6):1337-46.
Title: Role of Helicobacter pylori infection in aberrant DNA methylation along multistep gastric carcinogenesis.
Author: Shin, Cheol Min|Kim, Nayoung|Jung, Younmu|Park, Ji Hyun|Kang, Gyeong Hoon|Kim, Joo Sung|Jung, Hyun Chae|Song, In Sung
PMID: 20345486
Journal: Cancer Lett. 2010 Jun 28;292(2):237-45.
Title: Activation of 5-lipoxygenase is required for nicotine mediated epithelial-mesenchymal transition and tumor cell growth.
Author: Shin, Vivian Yvonne|Jin, Hong Chuan|Ng, Enders Kai On|Sung, Joseph Jao Yiu|Chu, Kent Man|Cho, Chi Hin
PMID: 20061081
Journal: Zhonghua Zhong Liu Za Zhi. 2011 Jan;33(1):37-41.
Title: [Expression of LOX and MMP-2 in gastric cancer tissue and the effects of LOX and MMP-2 on tumor invasion and metastasis].
Author: Ma, Li-Juan|Li, Yi-Gong|Huang, Ling|Han, Mei|Ma, Bai-Jing|Sun, Bo-Jian|Lin, Jia-Jing|Song, Ting-Ge
PMID: 21575462
Journal: Zhonghua Zhong Liu Za Zhi. 2011 May;33(5):331-3.
Title: [Effect of lysyl oxidase on migration and adhesion of human gastric cancer HGC-27 cells in vitro].
Author: Ma, Bai-jing|Huang, Ling|Han, Mei|Wang, Yu-qiao|Zhao, Jian-ning|Sun, Bo-jian|Lin, Jia-jing|Song, Ting-ge
PMID: 21875459
Journal: APMIS. 2011 Nov;119(11):762-8.
Title: Lysyl oxidase G473A polymorphism is closely associated with susceptibility to gastric cancer in a South Korean population.
Author: Yoon, Jung Hwan|Park, Jong Kyung|Kang, Young Hwi|Park, Yong Kyu|Nam, Suk Woo|Lee, Jung Young|Park, Won Sang
PMID: 21995629
Journal: Cancers (Basel). 2011 Aug 8;3(3):3156-68.
Title: Upregulation of leukotriene receptors in gastric cancer.
Author: Venerito, Marino|Kuester, Doerthe|Harms, Caroline|Schubert, Daniel|Wex, Thomas|Malfertheiner, Peter
PMID: 24212950
Journal: Can J Physiol Pharmacol. 2012 Feb;90(2):175-86.
Title: The role of transient receptor potential channel blockers in human gastric cancer cell viability.
Author: Kim, Byung Joo|Kim, Sung-Young|Lee, Sanghoon|Jeon, Ju-Hong|Matsui, Hirofumi|Kwon, Young Kyu|Kim, Seon Jeong|So, Insuk
PMID: 22308955
Journal: Oncol Lett. 2013 Mar;5(3):896-902.
Title: Upregulated expression of LOX is a novel independent prognostic marker of worse outcome in gastric cancer patients after curative surgery.
Author: Zhang, Qing|Jin, Xiao-Shun|Yang, Zhong-Yin|Wei, Min|Zhu, Xiao-Cheng|Wang, Ping|Liu, Bing-Ya|Gu, Qin-Long
PMID: 23425977
Journal: Int J Cancer. 2013 Nov;133(9):2034-42.
Title: Changes in aberrant DNA methylation after Helicobacter pylori eradication: a long-term follow-up study.
Author: Shin, Cheol Min|Kim, Nayoung|Lee, Hye Seung|Park, Ji Hyun|Ahn, Soyeon|Kang, Gyeong Hoon|Kim, Jung Mogg|Kim, Joo Sung|Lee, Dong Ho|Jung, Hyun Chae
PMID: 23595635
Journal: Tumour Biol. 2014 Oct;35(10):10547-54.
Title: Combined use of lysyl oxidase, carcino-embryonic antigen, and carbohydrate antigens improves the sensitivity of biomarkers in predicting lymph node metastasis and peritoneal metastasis in gastric cancer.
Author: Lai, Hao|Jin, Qinwen|Lin, Yuan|Mo, Xianwei|Li, Bo|He, Ke|Chen, Jiansi
PMID: 25060181
Journal: Am J Cancer Res. 2014 Nov 19;4(6):789-800. eCollection 2014.
Title: Silencing of hypoxia-inducible tumor suppressor lysyl oxidase gene by promoter methylation activates carbonic anhydrase IX in nasopharyngeal carcinoma.
Author: Sung, Fion L|Cui, Yan|Hui, Edwin P|Li, Lili|Loh, Thomas Ks|Tao, Qian|Chan, Anthony Tc
PMID: 25520868
Journal: Gastric Cancer. 2016 Apr;19(2):431-42.
Title: Lysyl oxidase is associated with the epithelial-mesenchymal transition of gastric cancer cells in hypoxia.
Author: Kasashima, Hiroaki|Yashiro, Masakazu|Kinoshita, Haruhito|Fukuoka, Tatsunari|Morisaki, Tamami|Masuda, Go|Sakurai, Katsunobu|Kubo, Naoshi|Ohira, Masaichi|Hirakawa, Kosei
PMID: 26100130
Journal: Int J Nanomedicine. 2017 Dec 27;13:161-174.
Title: Lysyl oxidase activates cancer stromal cells and promotes gastric cancer progression: quantum dot-based identification of biomarkers in cancer stromal cells.
Author: Peng, Chunwei|Liu, Jiuyang|Yang, Guifang|Li, Yan
PMID: 29343955
Journal: Bioorg Med Chem Lett. 2018 Oct 1;28(18):3113-3118.
Title: Inhibition of the LOX enzyme family members with old and new ligands. Selectivity analysis revisited.
Author: Hajdu, Istvan|Kardos, Jozsef|Major, Balazs|Fabo, Gabriella|Lorincz, Zsolt|Cseh, Sandor|Dorman, Gyorgy
PMID: 30098867
Journal: Int J Mol Med. 2018 Nov;42(5):2737-2749.
Title: Inhibition of lysyl oxidase expression by dextran sulfate affects invasion and migration of gastric cancer cells.
Author: Xu, Yuanyi|Wang, Xiaofei|Huang, Yunning|Ma, Yanmei|Jin, Xiu|Wang, Honghong|Wang, Juan
PMID: 30226558