Primary Site >> Stomach Cancer
Gene >> LOX
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Ref: Identification of silencing of nine genes in human gastric cancers. PMID: 12438262 Ref: [Expression of lysyl oxidase gene in upper digestive tract carcinomas and its clinical significance]. PMID: 12452073 |
Ref: Five-lipoxygenase-activating protein inhibitor MK-886 induces apoptosis in gastric cancer through upregulation of p27kip1 and bax. PMID: 14675240 Ref: Lysyl oxidase is a tumor suppressor gene inactivated by methylation and loss of heterozygosity in human gastric cancers. PMID: 15374948 |
Ref: High levels of aberrant DNA methylation in Helicobacter pylori-infected gastric mucosae and its possible association with gastric cancer risk. PMID: 16467114 Ref: Accumulation of DNA methylation is associated with tumor stage in gastric cancer. PMID: 16475210 Ref: CpG island methylation status in gastric carcinoma with and without infection of Epstein-Barr virus. PMID: 16707594 Ref: Multiple tumor suppressor genes are increasingly methylated with age in non-neoplastic gastric epithelia. PMID: 16952303 |
Ref: Methylation of tumor-related genes in neoadjuvant-treated gastric cancer: relation to therapy response and clinicopathologic and molecular features. PMID: 17785563 |
Ref: The long-term effect of Helicobacter pylori eradication on COX-1/2, 5-LOX and leukotriene receptors in patients with a risk gastritis phenotype--a link to gastric carcinogenesis. PMID: 18571838 |
Ref: Comparative analysis of DNA methylation between primary and metastatic gastric carcinoma. PMID: 19360301 Ref: A loss-of-function polymorphism in the propeptide domain of the LOX gene and breast cancer. PMID: 19654310 |
Ref: Activation of 5-lipoxygenase is required for nicotine mediated epithelial-mesenchymal transition and tumor cell growth. PMID: 20061081 Ref: Role of Helicobacter pylori infection in aberrant DNA methylation along multistep gastric carcinogenesis. PMID: 20345486 |
Ref: [Expression of LOX and MMP-2 in gastric cancer tissue and the effects of LOX and MMP-2 on tumor invasion and metastasis]. PMID: 21575462 Ref: [Effect of lysyl oxidase on migration and adhesion of human gastric cancer HGC-27 cells in vitro]. PMID: 21875459 Ref: Lysyl oxidase G473A polymorphism is closely associated with susceptibility to gastric cancer in a South Korean population. PMID: 21995629 Ref: Upregulation of leukotriene receptors in gastric cancer. PMID: 24212950 |
Ref: The role of transient receptor potential channel blockers in human gastric cancer cell viability. PMID: 22308955 |
Ref: Upregulated expression of LOX is a novel independent prognostic marker of worse outcome in gastric cancer patients after curative surgery. PMID: 23425977 Ref: Changes in aberrant DNA methylation after Helicobacter pylori eradication: a long-term follow-up study. PMID: 23595635 |
Ref: Combined use of lysyl oxidase, carcino-embryonic antigen, and carbohydrate antigens improves the sensitivity of biomarkers in predicting lymph node metastasis and peritoneal metastasis in gastric cancer. PMID: 25060181 Ref: Silencing of hypoxia-inducible tumor suppressor lysyl oxidase gene by promoter methylation activates carbonic anhydrase IX in nasopharyngeal carcinoma. PMID: 25520868 |
Ref: Lysyl oxidase is associated with the epithelial-mesenchymal transition of gastric cancer cells in hypoxia. PMID: 26100130 |
Ref: Lysyl oxidase activates cancer stromal cells and promotes gastric cancer progression: quantum dot-based identification of biomarkers in cancer stromal cells. PMID: 29343955 Ref: Inhibition of the LOX enzyme family members with old and new ligands. Selectivity analysis revisited. PMID: 30098867 Ref: Inhibition of lysyl oxidase expression by dextran sulfate affects invasion and migration of gastric cancer cells. PMID: 30226558 |