Literatures

Primary Site >> Colorectal Cancer

Gene >> LOX

1.
Journal:	Eur J Cancer. 1992;28A(4-5):767-73.
Title:	Comparative antitumour activity of vinblastine-isoleucinate and related vinca alkaloids in human tumour xenografts.
Author:	Hendriks, H R\|Langdon, S\|Berger, D P\|Breistol, K\|Fiebig, H H\|Fodstad, O\|Schwartsmann, G
PMID:	1524896

2.
Journal:	Anticancer Res. 1994 Nov-Dec;14(6B):2445-51.
Title:	Expression and release of plasminogen activators, their inhibitors and receptor by human tumor cell lines.
Author:	Buo, L\|Bjornland, K\|Karlsrud, T S\|Kvale, D\|Kjonniksen, I\|Fodstad, O\|Brandtzaeg, P\|Johansen, H T\|Aasen, A O
PMID:	7872665

3.
Journal:	Clin Cancer Res. 1995 Aug;1(8):847-57.
Title:	Preclinical antitumor efficacy of the polyamine analogue N1, N11-diethylnorspermine administered by multiple injection or continuous infusion.
Author:	Bernacki, R J\|Oberman, E J\|Seweryniak, K E\|Atwood, A\|Bergeron, R J\|Porter, C W
PMID:	9816054

4.
Journal:	J Med Chem. 1995 Feb 3;38(3):395-401.
Title:	Synthesis and antitumor activity of novel water soluble derivatives of camptothecin as specific inhibitors of topoisomerase I.
Author:	Luzzio, M J\|Besterman, J M\|Emerson, D L\|Evans, M G\|Lackey, K\|Leitner, P L\|McIntyre, G\|Morton, B\|Myers, P L\|Peel, M
PMID:	7853331

5.
Journal:	J Exp Ther Oncol. 1996 Mar;1(2):119-25.
Title:	Comparative antitumor activities of halichondrins and vinblastine against human tumor xenografts.
Author:	Fodstad, O\|Breistol, K\|Pettit, G R\|Shoemaker, R H\|Boyd, M R
PMID:	9414395

6.
Journal:	Cancer Res. 1996 Feb 1;56(3):538-43.
Title:	MKT-077, a novel rhodacyanine dye in clinical trials, exhibits anticarcinoma activity in preclinical studies based on selective mitochondrial accumulation.
Author:	Koya, K\|Li, Y\|Wang, H\|Ukai, T\|Tatsuta, N\|Kawakami, M\|Shishido\|Chen, L B
PMID:	8564968

7.
Journal:	J Med Chem. 1997 Sep 26;40(20):3151-60.
Title:	Synthesis and evaluation of novel rhodacyanine dyes that exhibit antitumor activity.
Author:	Kawakami, M\|Koya, K\|Ukai, T\|Tatsuta, N\|Ikegawa, A\|Ogawa, K\|Shishido, T\|Chen, L B
PMID:	9379434

8.
Journal:	Adv Exp Med Biol. 1997;400B:599-604.
Title:	Regulation of 15-lipoxygenase expression by cytokines.
Author:	Brinckmann, R\|Kuhn, H
PMID:	9547609

9.
Journal:	Clin Exp Metastasis. 1998 Jan;16(1):9-20.
Title:	Inhibition of establishment of primary and micrometastatic tumors by a urokinase plasminogen activator receptor antagonist.
Author:	Ignar, D M\|Andrews, J L\|Witherspoon, S M\|Leray, J D\|Clay, W C\|Kilpatrick, K\|Onori, J\|Kost, T\|Emerson, D L
PMID:	9502073

10.
Journal:	Oncol Res. 2000;12(3):127-35.
Title:	Tumor amplified protein expression therapy: Salmonella as a tumor-selective protein delivery vector.
Author:	Zheng, L M\|Luo, X\|Feng, M\|Li, Z\|Le, T\|Ittensohn, M\|Trailsmith, M\|Bermudes, D\|Lin, S L\|King, I C
PMID:	11216671

11.
Journal:	Cancer Res. 2001 Feb 1;61(3):1013-21.
Title:	In vitro and in vivo anticancer activities of synthetic macrocyclic ketone analogues of halichondrin B.
Author:	Towle, M J\|Salvato, K A\|Budrow, J\|Wels, B F\|Kuznetsov, G\|Aalfs, K K\|Welsh, S\|Zheng, W\|Seletsky, B M\|Palme, M H\|Habgood, G J\|Singer, L A\|Dipietro, L V\|Wang, Y\|Chen, J J\|Quincy, D A\|Davis, A\|Yoshimatsu, K\|Kishi, Y\|Yu, M J\|Littlefield, B A
PMID:	11221827

12.
Journal:	Cancer Res. 2001 Sep 1;61(17):6307-12.
Title:	Lipoxygenase modulation to reverse carcinogenesis.
Author:	Shureiqi, I\|Lippman, S M
PMID:	11522616

13.
Journal:	Int J Cancer. 2002 Feb 10;97(5):636-42.
Title:	Somatic mutations of the lysyl oxidase gene on chromosome 5q23.1 in colorectal tumors.
Author:	Csiszar, Katalin\|Fong, Sheri F T\|Ujfalusi, Aniko\|Krawetz, Stephen A\|Salvati, Eugene P\|Mackenzie, James W\|Boyd, Charles D
PMID:	11807790

14.
Journal:	J Pharmacol Exp Ther. 2004 Jan;308(1):66-72. Epub 2003 Oct 20.
Title:	Nicotine promoted colon cancer growth via epidermal growth factor receptor, c-Src, and 5-lipoxygenase-mediated signal pathway.
Author:	Ye, Yi N\|Liu, Edgar S L\|Shin, Vivian Y\|Wu, William K K\|Luo, Jiing C\|Cho, Chi H
PMID:	14569062

15.
Journal:	Carcinogenesis. 2004 Sep;25(9):1671-9.
Title:	Modulation of arachidonic acid metabolism by curcumin and related beta-diketone derivatives: effects on cytosolic phospholipase A(2), cyclooxygenases and 5-lipoxygenase.
Author:	Hong, Jungil\|Bose, Mousumi\|Ju, Jihyeung\|Ryu, Jae-Ha\|Chen, Xiaoxin\|Sang, Shengmin\|Lee, Mao-Jung\|Yang, Chung S
PMID:	15073046

16.
Journal:	Nucleic Acids Res. 2004 May 11;32(8):2660-74.
Title:	Pharmacological and genetic modulation of Wnt-targeted Cre-Lox-mediated gene expression in colorectal cancer cells.
Author:	Bordonaro, Michael\|Lazarova, Darina L\|Sartorelli, Alan C
PMID:	15141037

17.
Journal:	Prostaglandins Other Lipid Mediat. 2004 Jan;73(1-2):111-22.
Title:	15-LOX-1 inhibits p21 (Cip/WAF 1) expression by enhancing MEK-ERK 1/2 signaling in colon carcinoma cells.
Author:	Yoshinaga, Masahiro\|Buchanan, F Gregory\|DuBois, Raymond N
PMID:	15165036

18.
Journal:	Toxicology. 2004 Oct 15;203(1-3):179-88.
Title:	Contributory role of 5-lipoxygenase and its association with angiogenesis in the promotion of inflammation-associated colonic tumorigenesis by cigarette smoking.
Author:	Ye, Yi-Ni\|Liu, Edgar Shiu-Lam\|Shin, Vivian Yvonne\|Wu, William Ka-Kei\|Cho, Chi-Hin
PMID:	15363593

19.
Journal:	Carcinogenesis. 2005 Apr;26(4):827-34. Epub 2005 Jan 6.
Title:	Dual inhibition of 5-LOX and COX-2 suppresses colon cancer formation promoted by cigarette smoke.
Author:	Ye, Y N\|Wu, W K K\|Shin, V Y\|Bruce, I C\|Wong, B C Y\|Cho, C H
PMID:	15637091

20.
Journal:	Eur J Pharmacol. 2005 Sep 5;519(1-2):52-7.
Title:	A mechanistic study of colon cancer growth promoted by cigarette smoke extract.
Author:	Ye, Yi N\|Wu, William K K\|Shin, Vivian Y\|Cho, Chi H
PMID:	16125168

21.
Journal:	Mol Cancer Ther. 2006 Nov;5(11):2716-26.
Title:	Inhibition of 5-lipoxygenase by MK886 augments the antitumor activity of celecoxib in human colon cancer cells.
Author:	Cianchi, Fabio\|Cortesini, Camillo\|Magnelli, Lucia\|Fanti, Elena\|Papucci, Laura\|Schiavone, Nicola\|Messerini, Luca\|Vannacci, Alfredo\|Capaccioli, Sergio\|Perna, Federico\|Lulli, Matteo\|Fabbroni, Valentina\|Perigli, Giuliano\|Bechi, Paolo\|Masini, Emanuela
PMID:	17121918

22.
Journal:	World J Gastroenterol. 2006 Oct 21;12(39):6355-60.
Title:	Expression of 5-lipoxygenase in human colorectal cancer.
Author:	Soumaoro, Labile Togba\|Iida, Satoru\|Uetake, Hiroyuki\|Ishiguro, Megumi\|Takagi, Yoko\|Higuchi, Tetsuro\|Yasuno, Masamichi\|Enomoto, Masayuki\|Sugihara, Kenichi
PMID:	17072961

23.
Journal:	Cancer Res. 2007 Aug 15;67(16):7605-12.
Title:	Bin1 ablation increases susceptibility to cancer during aging, particularly lung cancer.
Author:	Chang, Mee Young\|Boulden, Janette\|Katz, Jessica B\|Wang, Liwei\|Meyer, Thomas J\|Soler, Alejandro Peralta\|Muller, Alexander J\|Prendergast, George C
PMID:	17699764

24.
Journal:	Photochem Photobiol. 2007 Sep-Oct;83(5):1174-85.
Title:	Modulation of hypericin photodynamic therapy by pretreatment with 12 various inhibitors of arachidonic acid metabolism in colon adenocarcinoma HT-29 cells.
Author:	Kleban, Jan\|Mikes, Jaromir\|Szilardiova, Beata\|Koval, Jan\|Sackova, Veronika\|Solar, Peter\|Horvath, Viktor\|Hofmanova, Jirina\|Kozubik, Alois\|Fedorocko, Peter
PMID:	17880512

25.
Journal:	J Photochem Photobiol B. 2008 Nov 13;93(2):108-18.
Title:	Mechanisms involved in the cell cycle and apoptosis of HT-29 cells pre-treated with MK-886 prior to photodynamic therapy with hypericin.
Author:	Kleban, Jan\|Mikes, Jaromir\|Horvath, Viktor\|Sackova, Veronika\|Hofmanova, Jirina\|Kozubik, Alois\|Fedorocko, Peter
PMID:	18771933

26.
Journal:	Clin Cancer Res. 2008 Oct 15;14(20):6525-30.
Title:	Overexpression of 5-lipoxygenase in colon polyps and cancer and the effect of 5-LOX inhibitors in vitro and in a murine model.
Author:	Melstrom, Laleh G\|Bentrem, David J\|Salabat, Mohammad R\|Kennedy, Timothy J\|Ding, Xian-Zhong\|Strouch, Matthew\|Rao, Sambasiva M\|Witt, Richard C\|Ternent, Charles A\|Talamonti, Mark S\|Bell, Richard H\|Adrian, Thomas A
PMID:	18927292

27.
Journal:	Gastroenterology. 2009 Oct;137(4):1358-66.e1-3.
Title:	Cyclooxygenase-2 inhibitors down-regulate osteopontin and Nr4A2-new therapeutic targets for colorectal cancers.
Author:	Zagani, Rachid\|Hamzaoui, Nadim\|Cacheux, Wulfran\|de Reynies, Aurelien\|Terris, Benoit\|Chaussade, Stanislas\|Romagnolo, Beatrice\|Perret, Christine\|Lamarque, Dominique
PMID:	19549529

28.
Journal:	Bioorg Med Chem. 2009 Aug 1;17(15):5605-13.
Title:	Urea and carbamate derivatives of primaquine: synthesis, cytostatic and antioxidant activities.
Author:	Simunovic, M\|Perkovic, I\|Zorc, B\|Ester, K\|Kralj, M\|Hadjipavlou-Litina, D\|Pontiki, E
PMID:	19581098

29.
Journal:	Curr Mol Med. 2009 Jun;9(5):565-79.
Title:	Role of lipoxins and resolvins as anti-inflammatory and proresolving mediators in colon cancer.
Author:	Janakiram, Naveena B\|Rao, Chinthalapally V
PMID:	19601807

30.
Journal:	J Biomed Biotechnol. 2009;2009:358230.
Title:	Modular Cre/lox system and genetic therapeutics for colorectal cancer.
Author:	Bordonaro, Michael
PMID:	19809520

31.
Journal:	Mol Cancer Ther. 2010 Jan;9(1):134-44.
Title:	Preclinical in vivo evaluation of efficacy, pharmacokinetics, and pharmacodynamics of a novel MEK1/2 kinase inhibitor RO5068760 in multiple tumor models.
Author:	Daouti, Sherif\|Higgins, Brian\|Kolinsky, Kenneth\|Packman, Kathryn\|Wang, Huisheng\|Rizzo, Christine\|Moliterni, John\|Huby, Nicholas\|Fotouhi, Nader\|Liu, Mei\|Goelzer, Petra\|Sandhu, Harpreet K\|Li, Jia Kui\|Railkar, Aruna\|Heimbrook, David\|Niu, Huifeng
PMID:	20053779

32.
Journal:	Prostaglandins Other Lipid Mediat. 2010 Nov;93(3-4):100-8.
Title:	Inhibition of arachidonic acid metabolism decreases tumor cell invasion and matrix metalloproteinase expression.
Author:	Koontongkaew, Sittichai\|Monthanapisut, Paopanga\|Saensuk, Theeranuch
PMID:	20654727

33.
Journal:	Int J Oncol. 2010 May;36(5):1183-91.
Title:	Cyclooxygenase-2 and 5-lipoxygenase pathways in diosgenin-induced apoptosis in HT-29 and HCT-116 colon cancer cells.
Author:	Lepage, Clemence\|Liagre, Bertrand\|Cook-Moreau, Jeanne\|Pinon, Aline\|Beneytout, Jean-Louis
PMID:	20372792

34.
Journal:	Clin Cancer Res. 2010 Jan 1;16(1):21-33.
Title:	Three DNA methylation epigenotypes in human colorectal cancer.
Author:	Yagi, Koichi\|Akagi, Kiwamu\|Hayashi, Hiroshi\|Nagae, Genta\|Tsuji, Shingo\|Isagawa, Takayuki\|Midorikawa, Yutaka\|Nishimura, Yoji\|Sakamoto, Hirohiko\|Seto, Yasuyuki\|Aburatani, Hiroyuki\|Kaneda, Atsushi
PMID:	20028768

35.
Journal:	Cancer Res. 2011 Mar 1;71(5):1647-57.
Title:	The HIF-1-inducible lysyl oxidase activates HIF-1 via the Akt pathway in a positive regulation loop and synergizes with HIF-1 in promoting tumor cell growth.
Author:	Pez, Floriane\|Dayan, Frederic\|Durivault, Jerome\|Kaniewski, Bastien\|Aimond, Geraldine\|Le Provost, Gabrielle S\|Deux, Blandine\|Clezardin, Philippe\|Sommer, Pascal\|Pouyssegur, Jacques\|Reynaud, Caroline
PMID:	21239473

36.
Journal:	J Natl Cancer Inst. 2011 Mar 2;103(5):407-24.
Title:	The role of lysyl oxidase in SRC-dependent proliferation and metastasis of colorectal cancer.
Author:	Baker, Ann-Marie\|Cox, Thomas R\|Bird, Demelza\|Lang, Georgina\|Murray, Graeme I\|Sun, Xiao-Feng\|Southall, Stacey M\|Wilson, Jon R\|Erler, Janine T
PMID:	21282564

37.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2011 Nov;301(5):G856-64.
Title:	Intestinal epithelial-specific PTEN inactivation results in tumor formation.
Author:	Byun, Do-Sun\|Ahmed, Naseem\|Nasser, Shannon\|Shin, Joongho\|Al-Obaidi, Sheren\|Goel, Sanjay\|Corner, Georgia A\|Wilson, Andrew J\|Flanagan, Dustin J\|Williams, David S\|Augenlicht, Leonard H\|Vincan, Elizabeth\|Mariadason, John M
PMID:	21836055

38.
Journal:	J Agric Food Chem. 2011 Sep 28;59(18):9861-9.
Title:	Composition and mechanism of antitumor effects of Hericium erinaceus mushroom extracts in tumor-bearing mice.
Author:	Kim, Sung Phil\|Kang, Mi Young\|Kim, Jae Ho\|Nam, Seok Hyun\|Friedman, Mendel
PMID:	21846141

39.
Journal:	Cancer Prev Res (Phila). 2011 Dec;4(12):2015-26.
Title:	Chemoprevention of colon and small intestinal tumorigenesis in APC(Min/+) mice by licofelone, a novel dual 5-LOX/COX inhibitor: potential implications for human colon cancer prevention.
Author:	Mohammed, Altaf\|Janakiram, Naveena B\|Li, Qian\|Choi, Chang-In\|Zhang, Yuting\|Steele, Vernon E\|Rao, Chinthalapally V
PMID:	21885812

40.
Journal:	Br J Cancer. 2012 Oct 23;107(9):1514-7.
Title:	beta-catenin negatively regulates expression of the prostaglandin transporter PGT in the normal intestinal epithelium and colorectal tumour cells: a role in the chemopreventive efficacy of aspirin?
Author:	Smartt, H J M\|Greenhough, A\|Ordonez-Moran, P\|Al-Kharusi, M\|Collard, T J\|Mariadason, J M\|Huelsken, J\|Williams, A C\|Paraskeva, C
PMID:	23033009

41.
Journal:	Gastroenterology. 2012 Mar;142(3):562-571.e2.
Title:	Smad4-mediated signaling inhibits intestinal neoplasia by inhibiting expression of beta-catenin.
Author:	Freeman, Tanner J\|Smith, J Joshua\|Chen, Xi\|Washington, M Kay\|Roland, Joseph T\|Means, Anna L\|Eschrich, Steven A\|Yeatman, Timothy J\|Deane, Natasha G\|Beauchamp, R Daniel
PMID:	22115830

42.
Journal:	Gut. 2012 Sep;61(9):1306-14.
Title:	beta-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells.
Author:	Smartt, Helena J M\|Greenhough, Alexander\|Ordonez-Moran, Paloma\|Talero, Elena\|Cherry, Catherine A\|Wallam, Catherine A\|Parry, Lee\|Al Kharusi, Manal\|Roberts, Heather R\|Mariadason, John M\|Clarke, Alan R\|Huelsken, Joerg\|Williams, Ann C\|Paraskeva, Chris
PMID:	22082586

43.
Journal:	World J Surg Oncol. 2012 Sep 26;10:200.
Title:	Cyclooxygenase/lipoxygenase shunting lowers the anti-cancer effect of cyclooxygenase-2 inhibition in colorectal cancer cells.
Author:	Ganesh, Radhakrishnan\|Marks, Daniel J B\|Sales, Kevin\|Winslet, Marc C\|Seifalian, Alexander M
PMID:	23013454

44.
Journal:	Oncogene. 2013 Apr 4;32(14):1863-8.
Title:	Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK.
Author:	Baker, A-M\|Bird, D\|Lang, G\|Cox, T R\|Erler, J T
PMID:	22641216

45.
Journal:	Prostaglandins Other Lipid Mediat. 2013 Jul-Aug;104-105:139-43.
Title:	Eicosanoid profiling in colon cancer: emergence of a pattern.
Author:	Zuo, Xiangsheng\|Shureiqi, Imad
PMID:	22960430

46.
Journal:	Cancer Res. 2013 Jan 15;73(2):583-94.
Title:	Lysyl oxidase plays a critical role in endothelial cell stimulation to drive tumor angiogenesis.
Author:	Baker, Ann-Marie\|Bird, Demelza\|Welti, Jonathan C\|Gourlaouen, Morgane\|Lang, Georgina\|Murray, Graeme I\|Reynolds, Andrew R\|Cox, Thomas R\|Erler, Janine T
PMID:	23188504

47.
Journal:	Bioorg Med Chem. 2013 May 1;21(9):2551-9.
Title:	Novel dual cyclooxygenase and lipoxygenase inhibitors targeting hyaluronan-CD44v6 pathway and inducing cytotoxicity in colon cancer cells.
Author:	Misra, Suniti\|Ghatak, Shibnath\|Patil, Neha\|Dandawate, Prasad\|Ambike, Vinita\|Adsule, Shreelekha\|Unni, Deepak\|Venkateswara Swamy, K\|Padhye, Subhash
PMID:	23517721

48.
Journal:	Acta Biochim Biophys Sin (Shanghai). 2013 Sep;45(9):709-19.
Title:	5-lipoxygenase antagonist therapy: a new approach towards targeted cancer chemotherapy.
Author:	Bishayee, Kausik\|Khuda-Bukhsh, Anisur Rahman
PMID:	23752617

49.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2013 Nov 15;305(10):G659-66.
Title:	Lysyl oxidase in colorectal cancer.
Author:	Cox, Thomas R\|Erler, Janine T
PMID:	24008360

50.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2013 Sep;16(9):895-7.
Title:	[Association of 5-lipoxygenase expression and clinicopathological factors in colorectal carcinoma].
Author:	Li, Yue-chun\|Wang, Dong-xia\|Li, Cai-shi\|Ye, Zhen-peng\|Wu, Zhi-ming\|Chen, Jian-hua
PMID:	24062003

51.
Journal:	Eur J Surg Oncol. 2014 Jun;40(6):731-8.
Title:	Evaluation of serum lysyl oxidase as a blood test for colorectal cancer.
Author:	Ward, S T\|Weston, C J\|Hepburn, E\|Damery, S\|Hejmadi, R K\|Morton, D G\|Middleton, G\|Ismail, T\|Adams, D H
PMID:	24246612

52.
Journal:	Gan To Kagaku Ryoho. 2014 Nov;41(12):1764-6.
Title:	[A case of rectal cancer with brain metastasis successfully treated with combined modality therapy - a case report].
Author:	Nishimura, Junya\|Noda, Eiji\|Kitayama, Kishu\|Nomura, Shinya\|Teraoka, Hitoshi\|Nishino, Hiroji\|Hirakawa, Kosei
PMID:	25731322

53.
Journal:	PLoS One. 2014 Nov 18;9(11):e113513.
Title:	Examining the polymorphisms in the hypoxia pathway genes in relation to outcome in colorectal cancer.
Author:	Haja Mohideen, Asan M S\|Hyde, Angela\|Squires, Jessica\|Wang, Jing\|Dicks, Elizabeth\|Younghusband, Ban\|Parfrey, Patrick\|Green, Roger\|Savas, Sevtap
PMID:	25405996

54.
Journal:	Med Chem Res. 2014 Aug 1;23(8):3836-3851.
Title:	Isothiocyanate analogs targeting CD44 receptor as an effective strategy against colon cancer.
Author:	Misra, Suniti\|Ghatak, Shibnath\|Vyas, Alok\|O'Brien, Paul\|Markwald, Roger R\|Khetmalas, Madhukar\|Hascall, Vincent C\|McCarthy, James B\|Karamanos, Nikos K\|Tammi, Markku I\|Tammi, Raija H\|Prestwitch, Glenn D\|Padhye, Subhash
PMID:	25013352

55.
Journal:	Cancer Lett. 2014 Jun 1;347(2):191-5.
Title:	Colon-specific tumorigenesis in mice driven by Cre-mediated inactivation of Apc and activation of mutant Kras.
Author:	Byun, Alexander J\|Hung, Kenneth E\|Fleet, James C\|Bronson, Roderick T\|Mason, Joel B\|Garcia, Paloma E\|Crott, Jimmy W
PMID:	24632531

56.
Journal:	Oncol Lett. 2014 Feb;7(2):513-518.
Title:	Study of the polymorphisms of cyclooxygenase-2 (-765G>C) and 5-lipoxygenase (1708G>A) in patients with colorectal cancer.
Author:	Pimenta, Celia Aparecida Marques\|Latini, Flavia Roche Moreira\|DE Lima, Jacqueline Miranda\|DA Silva, Tiago Donizetti\|Felipe, Aledson Vitor\|DE Lima Pazine, Vanessa Maria\|Forones, Nora Manoukian
PMID:	24396479

57.
Journal:	Bioorg Med Chem Lett. 2014 Jan 1;24(1):317-24.
Title:	Novel di-tertiary-butyl phenylhydrazones as dual cyclooxygenase-2/5-lipoxygenase inhibitors: synthesis, COX/LOX inhibition, molecular modeling, and insights into their cytotoxicities.
Author:	Ghatak, Shibnath\|Vyas, Alok\|Misra, Suniti\|O'Brien, Paul\|Zambre, Ajit\|Fresco, Victor M\|Markwald, Roger R\|Swamy, K Venkateshwara\|Afrasiabi, Zahra\|Choudhury, Amitava\|Khetmalas, Madhukar\|Padhye, Subhash
PMID:	24295787

58.
Journal:	Physiol Rep. 2015 Jul;3(7). pii: 3/7/e12417.
Title:	Leukotriene D4-induced Caco-2 cell proliferation is mediated by prostaglandin E2 synthesis.
Author:	Cabral, Marisol\|Martin-Venegas, Raquel\|Moreno, Juan J
PMID:	26216432

59.
Journal:	Radiother Oncol. 2015 Sep;116(3):346-51.
Title:	The usability of a 15-gene hypoxia classifier as a universal hypoxia profile in various cancer cell types.
Author:	Sorensen, Brita Singers\|Knudsen, Anders\|Wittrup, Catja Foged\|Nielsen, Steffen\|Aggerholm-Pedersen, Ninna\|Busk, Morten\|Horsman, Michael\|Hoyer, Morten\|Bouchelouche, Pierre Nourdine\|Overgaard, Jens\|Alsner, Jan
PMID:	26169282

60.
Journal:	Cancer Prev Res (Phila). 2015 Apr;8(4):327-37.
Title:	Improved innate immune responses by Frondanol A5, a sea cucumber extract, prevent intestinal tumorigenesis.
Author:	Janakiram, Naveena B\|Mohammed, Altaf\|Bryant, Taylor\|Lightfoot, Stan\|Collin, Peter D\|Steele, Vernon E\|Rao, Chinthalapally V
PMID:	25657017

61.
Journal:	Oncotarget. 2015 Feb 20;6(5):2879-88.
Title:	12/15 Lipoxygenase regulation of colorectal tumorigenesis is determined by the relative tumor levels of its metabolite 12-HETE and 13-HODE in animal models.
Author:	Chang, Jian\|Jiang, Li\|Wang, Yinqiu\|Yao, Bing\|Yang, Shilin\|Zhang, Bixiang\|Zhang, Ming-Zhi
PMID:	25576922

62.
Journal:	Mol Genet Genomics. 2015 Feb;290(1):23-8.
Title:	Lysyl oxidase rs1800449 polymorphism and cancer risk among Asians: evidence from a meta-analysis and a case-control study of colorectal cancer.
Author:	Gao, Xueren\|Zhang, Shulong\|Zhu, Zhansheng
PMID:	25112403

63.
Journal:	Anticancer Agents Med Chem. 2015;15(8):1066-77.
Title:	5-Lipoxygenase and cyclooxygenase inhibitory dammarane triterpenoid 1 from Borassus flabellifer seed coat inhibits tumor necrosis factor-alpha secretion in LPSInduced THP-1 human monocytes and induces apoptosis in MIA PaCa-2 pancreatic cancer cells.
Author:	Yarla, Nagendra Sastry\|Azad, Rajaram\|Basha, Mahaboob\|Rajack, Abdul\|Kaladhar, D S V G K\|Allam, Bharat Kumar\|Pragada, Rajeswara Rao\|Singh, Krishna Nand\|K, Sunanda Kumari\|Pallu, Reddanna\|Parimi, Umadevi\|Bishayee, Anupam\|Duddukuri, Govinda Rao
PMID:	25642980

64.
Journal:	J Gastroenterol. 2016 May;51(5):447-57.
Title:	Mouse model of proximal colon-specific tumorigenesis driven by microsatellite instability-induced Cre-mediated inactivation of Apc and activation of Kras.
Author:	Kawaguchi, Yasuo\|Hinoi, Takao\|Saito, Yasufumi\|Adachi, Tomohiro\|Miguchi, Masashi\|Niitsu, Hiroaki\|Sasada, Tatsunari\|Shimomura, Manabu\|Egi, Hiroyuki\|Oka, Shiro\|Tanaka, Shinji\|Chayama, Kazuaki\|Sentani, Kazuhiro\|Oue, Naohide\|Yasui, Wataru\|Ohdan, Hideki
PMID:	26361962

65.
Journal:	Dig Dis Sci. 2016 Apr;61(4):1069-79.
Title:	An Inducible, Large-Intestine-Specific Transgenic Mouse Model for Colitis and Colitis-Induced Colon Cancer Research.
Author:	Wang, Fa\|Johnson, Robert L\|Snyder, Paul W\|DeSmet, Marsha L\|Fleet, James C
PMID:	26631394

66.
Journal:	Curr Med Chem. 2016;23(11):1131-8.
Title:	The Co-regulatory Role of 5-Lipoxygenase and Cyclooxygenase-2 in the Carcinogenesis and their Promotion by Cigarette Smoking in Colons.
Author:	Shen, J\|Li, W X\|Xiao, Z G\|Zhang, L\|Li, M X\|Li, L F\|Hu, W\|Lu, L\|Boudreau, F\|Cho, C H
PMID:	26997150

67.
Journal:	Free Radic Biol Med. 2016 Jun;95:190-9.
Title:	Vitamin E metabolite 13'-carboxychromanols inhibit pro-inflammatory enzymes, induce apoptosis and autophagy in human cancer cells by modulating sphingolipids and suppress colon tumor development in mice.
Author:	Jang, Yumi\|Park, Na-Young\|Rostgaard-Hansen, Agnetha Linn\|Huang, Jianjie\|Jiang, Qing
PMID:	27016075

68.
Journal:	Clin Cancer Res. 2016 Sep 1;22(17):4491-504.
Title:	Lysyl Oxidase (LOX) Transcriptionally Regulates SNAI2 Expression and TIMP4 Secretion in Human Cancers.
Author:	Boufraqech, Myriem\|Zhang, Lisa\|Nilubol, Naris\|Sadowski, Samira M\|Kotian, Shweta\|Quezado, Martha\|Kebebew, Electron
PMID:	27029493

69.
Journal:	Int J Environ Res Public Health. 2016 Jun 28;13(7). pii: ijerph13070635.
Title:	Lysyl Oxidase Gene G473A Polymorphism and Cigarette Smoking in Association with a High Risk of Lung and Colorectal Cancers in a North Chinese Population.
Author:	Wang, Guoli\|Shen, Yanqing\|Cheng, Guang\|Bo, Haimei\|Lin, Jia\|Zheng, Maogen\|Li, Jianmin\|Zhao, Yinzhi\|Li, Wande
PMID:	27367711

70.
Journal:	Oncotarget. 2017 May 23;8(21):34773-34786.
Title:	Cysteinyl leukotriene receptor 1 facilitates tumorigenesis in a mouse model of colitis-associated colon cancer.
Author:	Osman, Janina\|Savari, Sayeh\|Chandrashekar, Naveen Kumar\|Bellamkonda, Kishan\|Douglas, Desiree\|Sjolander, Anita
PMID:	28410235

71.
Journal:	Oncol Lett. 2017 Dec;14(6):7767-7772.
Title:	Herbal compound Teng-Long-Bu-Zhong-Tang inhibits metastasis in human RKO colon carcinoma.
Author:	Wei, Meng-Meng\|Wang, Shuang-Shuang\|Zheng, Jia-Lu\|Chen, Jin-Jun\|Yan, Xia\|An, Hong-Mei\|Hu, Bing
PMID:	29344222

72.
Journal:	Int J Biol Sci. 2017 Nov 1;13(11):1450-1457.
Title:	Human colorectal cancer progression correlates with LOX-induced ECM stiffening.
Author:	Wei, Bo\|Zhou, Xueling\|Liang, Chenghua\|Zheng, Xiaoming\|Lei, Purun\|Fang, Jiafeng\|Han, Xiaoyan\|Wang, Lijing\|Qi, Cuiling\|Wei, Hongbo
PMID:	29209148

73.
Journal:	Sichuan Da Xue Xue Bao Yi Xue Ban. 2017 Jul;48(4):566-569.
Title:	[Expression of LOX in Colorectal Cancer Tissues and Its Relationship with Progress and Prognosis].
Author:	Shi, Xiao-Ming\|Zhao, Wei\|Yang, Yong-Bin\|Lu, Bo-Nan
PMID:	29130678

74.
Journal:	Cancer Lett. 2017 Dec 1;410:82-91.
Title:	Ras inhibitors display an anti-metastatic effect by downregulation of lysyl oxidase through inhibition of the Ras-PI3K-Akt-HIF-1alpha pathway.
Author:	Yoshikawa, Yoko\|Takano, Osamu\|Kato, Ichiro\|Takahashi, Yoshihisa\|Shima, Fumi\|Kataoka, Tohru
PMID:	28951129

75.
Journal:	Oncotarget. 2016 May 26;8(36):60015-60024.
Title:	Nuclear expression of lysyl oxidase enzyme is an independent prognostic factor in rectal cancer patients.
Author:	Liu, Na\|Cox, Thomas R\|Cui, Weiyingqi\|Adell, Gunnar\|Holmlund, Birgitta\|Ping, Jie\|Jarlsfelt, Ingvar\|Erler, Janine T\|Sun, Xiao-Feng
PMID:	28947950

76.
Journal:	Cell Rep. 2017 Apr 25;19(4):774-784.
Title:	Blocking Surgically Induced Lysyl Oxidase Activity Reduces the Risk of Lung Metastases.
Author:	Rachman-Tzemah, Chen\|Zaffryar-Eilot, Shelly\|Grossman, Moran\|Ribero, Dario\|Timaner, Michael\|Maki, Joni M\|Myllyharju, Johanna\|Bertolini, Francesco\|Hershkovitz, Dov\|Sagi, Irit\|Hasson, Peleg\|Shaked, Yuval
PMID:	28445728

77.
Journal:	Cancer Res. 2017 Jan 15;77(2):268-278.
Title:	Lysyl Oxidase Is a Strong Determinant of Tumor Cell Colonization in Bone.
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PMID:	27742687

78.
Journal:	Biochem Biophys Res Commun. 2018 Jan 13. pii: S0006-291X(18)30067-6.
Title:	TEMPORARY REMOVAL: Inhibition of COX-2 and 5-LOX regulates the progression of colorectal cancer by promoting PTEN and suppressing PI3K/AKT pathway.
Author:	Chang, Jian\|Tang, Nan\|Fang, Qi\|Zhu, Kongfan\|Liu, Lei\|Xiong, Xingcheng\|Zhu, Zhongchao\|Zhang, Bixiang\|Zhang, Mingzhi\|Tao, Jing
PMID:	29339153

79.
Journal:	Thorac Cancer. 2018 Jul;9(7):785-793.
Title:	Lysyl oxidase: A colorectal cancer biomarker of lung and hepatic metastasis.
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PMID:	29766649

80.
Journal:	J Crohns Colitis. 2018 Aug 18. pii: 5076185.
Title:	Rectal insulin instillation inhibits inflammation and tumor development in chemically-induced colitis.
Author:	Yassin, Mohammad\|Sadowska, Zuzanna\|Tritsaris, Katerina\|Kissow, Hannelouise\|Hansen, Camilla H F\|Forman, Julie L\|Rogler, Gerhard\|Troelsen, Jesper T\|Pedersen, Anders E\|Olsen, Jorgen
PMID:	30137286

81.
Journal:	PLoS One. 2018 Nov 2;13(11):e0206568.
Title:	Validation of near infrared fluorescence (NIRF) probes in vivo with dual laser NIRF endoscope.
Author:	Shrivastav, Manisha\|Gounaris, Elias\|Khan, Mohammad W\|Ko, Jeffrey\|Ryu, Stacy H\|Bogyo, Matthew\|Larson, Andrew\|Barret, Terrence A\|Bentrem, David J
PMID:	30388158