Primary Site >> Colorectal Cancer

Gene >> LIMK1

Journal: Thromb Res. 2010 Jun;125(6):e323-8.
Title: Coagulation Factor Xa inhibits cancer cell migration via LIMK1-mediated cofilin inactivation.
Author: Borensztajn, Keren|Peppelenbosch, Maikel P|Spek, C Arnold
PMID: 20347121
Journal: BMC Biol. 2012 Aug 10;10:72.
Title: A novel Rho-dependent pathway that drives interaction of fascin-1 with p-Lin-11/Isl-1/Mec-3 kinase (LIMK) 1/2 to promote fascin-1/actin binding and filopodia stability.
Author: Jayo, Asier|Parsons, Maddy|Adams, Josephine C
PMID: 22883572
Journal: Oncol Rep. 2013 Feb;29(2):605-12.
Title: DADS downregulates the Rac1-ROCK1/PAK1-LIMK1-ADF/cofilin signaling pathway, inhibiting cell migration and invasion.
Author: Zhou, Yujuan|Su, Jian|Shi, Ling|Liao, Qianjin|Su, Qi
PMID: 23233092
Journal: Mol Cancer Res. 2013 Feb;11(2):109-21.
Title: Knockdown of PAK4 or PAK1 inhibits the proliferation of mutant KRAS colon cancer cells independently of RAF/MEK/ERK and PI3K/AKT signaling.
Author: Tabusa, Hana|Brooks, Teresa|Massey, Andrew J
PMID: 23233484
Journal: Gut. 2014 Mar;63(3):480-93.
Title: Reduced LIMK2 expression in colorectal cancer reflects its role in limiting stem cell proliferation.
Author: Lourenco, Filipe C|Munro, June|Brown, Jennifer|Cordero, Julia|Stefanatos, Rhoda|Strathdee, Karen|Orange, Clare|Feller, Stephan M|Sansom, Owen J|Vidal, Marcos|Murray, Graeme I|Olson, Michael F
PMID: 23585469
Journal: Gastroenterology. 2014 Jul;147(1):196-208.e13.
Title: Loss of SMAD4 alters BMP signaling to promote colorectal cancer cell metastasis via activation of Rho and ROCK.
Author: Voorneveld, Philip W|Kodach, Liudmila L|Jacobs, Rutger J|Liv, Nalan|Zonnevylle, A Christiaan|Hoogenboom, Jacob P|Biemond, Izak|Verspaget, Hein W|Hommes, Daniel W|de Rooij, Karien|van Noesel, Carel J M|Morreau, Hans|van Wezel, Tom|Offerhaus, G Johan A|van
PMID: 24704720
Journal: Oncotarget. 2016 Nov 8;7(45):73739-73753.
Title: The other face of miR-17-92a cluster, exhibiting tumor suppressor effects in prostate cancer.
Author: Ottman, Richard|Levy, Jenna|Grizzle, William E|Chakrabarti, Ratna
PMID: 27650539
Journal: Sci Rep. 2017 Mar 30;7:45624.
Title: Downregulation of LIMK1-ADF/cofilin by DADS inhibits the migration and invasion of colon cancer.
Author: Su, Jian|Zhou, Yujuan|Pan, Zhibing|Shi, Ling|Yang, Jing|Liao, Aijun|Liao, Qianjin|Su, Qi
PMID: 28358024
Journal: Cancer Med. 2017 Jun;6(6):1331-1340.
Title: MiR-145 inhibits human colorectal cancer cell migration and invasion via PAK4-dependent pathway.
Author: Sheng, Nengquan|Tan, Gewen|You, Weiqiang|Chen, Hongqi|Gong, Jianfeng|Chen, Di|Zhang, Huizhen|Wang, Zhigang
PMID: 28440035
Journal: Br J Cancer. 2017 Aug 8;117(4):563-571.
Title: LIM kinase 1 interacts with myosin-9 and alpha-actinin-4 and promotes colorectal cancer progression.
Author: Liao, Qing|Li, Rui|Zhou, Rui|Pan, Zhihua|Xu, Lijun|Ding, Yanqing|Zhao, Liang
PMID: 28664914
Journal: Virchows Arch. 2018 May;472(5):727-737.
Title: LIMK/cofilin pathway and Slingshot are implicated in human colorectal cancer progression and chemoresistance.
Author: Aggelou, Helen|Chadla, Panagiota|Nikou, Sofia|Karteri, Sofia|Maroulis, Ioannis|Kalofonos, Haralabos P|Papadaki, Helen|Bravou, Vasiliki
PMID: 29352327
Journal: Exp Cell Res. 2018 Aug 1;369(1):158-165.
Title: PRP4 kinase induces actin rearrangement and epithelial-mesenchymal transition through modulation of the actin-binding protein cofilin.
Author: Islam, Salman Ul|Ahmed, Muhammad Bilal|Lee, Su Jin|Shehzad, Adeeb|Sonn, Jong Kyung|Kwon, Oh-Shin|Lee, Young Sup
PMID: 29787735
Journal: Cell Death Dis. 2018 Jul 3;9(7):749.
Title: Imbalanced LIMK1 and LIMK2 expression leads to human colorectal cancer progression and metastasis via promoting beta-catenin nuclear translocation.
Author: Zhang, Yue|Li, Aimin|Shi, Jiaolong|Fang, Yuxin|Gu, Chuncai|Cai, Jianqun|Lin, Chuang|Zhao, Liang|Liu, Side
PMID: 29970879