Primary Site >> Liver Cancer
Gene >> LGR5
| 1. | |||||||||||
| Journal: | Hepatology. 2003 Mar;37(3):528-33. | ||||||||||
| Title: | Overexpression of orphan G-protein-coupled receptor, Gpr49, in human hepatocellular carcinomas with beta-catenin mutations. | ||||||||||
| Author: | Yamamoto, Yoshiya|Sakamoto, Michiie|Fujii, Gen|Tsuiji, Hitomi|Kenetaka, Kengo|Asaka, Masahiro|Hirohashi, Setsuo | ||||||||||
| PMID: | 12601349 | ||||||||||
| 2. | |||||||||||
| Journal: | Oncogene. 2007 Feb 1;26(5):774-80. | ||||||||||
| Title: | Differential effects of inactivated Axin1 and activated beta-catenin mutations in human hepatocellular carcinomas. | ||||||||||
| Author: | Zucman-Rossi, J|Benhamouche, S|Godard, C|Boyault, S|Grimber, G|Balabaud, C|Cunha, A S|Bioulac-Sage, P|Perret, C | ||||||||||
| PMID: | 16964294 | ||||||||||
| 3. | |||||||||||
| Journal: | Dis Esophagus. 2010 Feb;23(2):168-74. | ||||||||||
| Title: | Lgr5, an intestinal stem cell marker, is abnormally expressed in Barrett's esophagus and esophageal adenocarcinoma. | ||||||||||
| Author: | Becker, L|Huang, Q|Mashimo, H | ||||||||||
| PMID: | 19549212 | ||||||||||
| 4. | |||||||||||
| Journal: | J Virol. 2011 Dec;85(23):12292-303. | ||||||||||
| Title: | Hepatitis C virus-induced cancer stem cell-like signatures in cell culture and murine tumor xenografts. | ||||||||||
| Author: | Ali, Naushad|Allam, Heba|May, Randal|Sureban, Sripathi M|Bronze, Michael S|Bader, Ted|Umar, Shahid|Anant, Srikant|Houchen, Courtney W | ||||||||||
| PMID: | 21937640 | ||||||||||
| 5. | |||||||||||
| Journal: | Clin Cancer Res. 2012 Sep 15;18(18):4997-5007. | ||||||||||
| Title: | Wnt-pathway activation in two molecular classes of hepatocellular carcinoma and experimental modulation by sorafenib. | ||||||||||
| Author: | Lachenmayer, Anja|Alsinet, Clara|Savic, Radoslav|Cabellos, Laia|Toffanin, Sara|Hoshida, Yujin|Villanueva, Augusto|Minguez, Beatriz|Newell, Philippa|Tsai, Hung-Wen|Barretina, Jordi|Thung, Swan|Ward, Stephen C|Bruix, Jordi|Mazzaferro, Vincenzo|Schwartz, Myr | ||||||||||
| PMID: | 22811581 | ||||||||||
| 6. | |||||||||||
| Journal: | Clin Exp Metastasis. 2013 Feb;30(2):189-200. | ||||||||||
| Title: | Transcriptional profiling identifies genes induced by hepatocyte-derived extracellular matrix in metastatic human colorectal cancer cell lines. | ||||||||||
| Author: | Zvibel, Isabel|Wagner, Adam|Pasmanik-Chor, Metsada|Varol, Chen|Oron-Karni, Varda|Santo, Erwin M|Halpern, Zamir|Kariv, Revital | ||||||||||
| PMID: | 22930170 | ||||||||||
| 7. | |||||||||||
| Journal: | Exp Cell Res. 2013 Feb 1;319(3):113-21. | ||||||||||
| Title: | Leucine-rich repeat-containing G protein-coupled receptor 5 regulates epithelial cell phenotype and survival of hepatocellular carcinoma cells. | ||||||||||
| Author: | Fukuma, Mariko|Tanese, Keiji|Effendi, Kathryn|Yamazaki, Ken|Masugi, Yohei|Suda, Mariko|Sakamoto, Michiie | ||||||||||
| PMID: | 23127514 | ||||||||||
| 8. | |||||||||||
| Journal: | Liver Cancer. 2014 Oct;3(3-4):451-7. | ||||||||||
| Title: | Overexpression of Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 5 (LGR5) Represents a Typical Wnt/beta-Catenin Pathway-Activated Hepatocellular Carcinoma. | ||||||||||
| Author: | Effendi, Kathryn|Yamazaki, Ken|Fukuma, Mariko|Sakamoto, Michiie | ||||||||||
| PMID: | 26280006 | ||||||||||
| 9. | |||||||||||
| Journal: | Oncogene. 2015 Jun 11;34(24):3188-98. | ||||||||||
| Title: | Lysine-specific demethylase 1 promotes the stemness and chemoresistance of Lgr5(+) liver cancer initiating cells by suppressing negative regulators of beta-catenin signaling. | ||||||||||
| Author: | Lei, Z-J|Wang, J|Xiao, H-L|Guo, Y|Wang, T|Li, Q|Liu, L|Luo, X|Fan, L-L|Lin, L|Mao, C-Y|Wang, S-N|Wei, Y-L|Lan, C-H|Jiang, J|Yang, X-J|Liu, P-D|Chen, D-F|Wang, B | ||||||||||
| PMID: | 25893304 | ||||||||||
| 10. | |||||||||||
| Journal: | Oncogene. 2015 Jun 11;34(24):3214. | ||||||||||
| Title: | Lysine-specific demethylase 1 promotes the stemness and chemoresistance of Lgr5+ liver cancer initiating cells by suppressing negative regulators of beta-catenin signaling. | ||||||||||
| Author: | Lei, Z-J|Wang, J|Xiao, H-L|Guo, Y|Wang, T|Li, Q|Liu, L|Luo, X|Fan, L-L|Lin, L|Mao, C-Y|Wang, S-N|Wei, Y-L|Lan, C-H|Jiang, J|Yang, X-J|Liu, P-D|Chen, D-F|Wang, B | ||||||||||
| PMID: | 26062983 | ||||||||||
| 11. | |||||||||||
| Journal: | Oncotarget. 2016 Jun 28;7(26):39026-39043. | ||||||||||
| Title: | De novo HAPLN1 expression hallmarks Wnt-induced stem cell and fibrogenic networks leading to aggressive human hepatocellular carcinomas. | ||||||||||
| Author: | Mebarki, Sihem|Desert, Romain|Sulpice, Laurent|Sicard, Marie|Desille, Mireille|Canal, Frederic|Dubois-Pot Schneider, Helene|Bergeat, Damien|Turlin, Bruno|Bellaud, Pascale|Lavergne, Elise|Le Guevel, Remy|Corlu, Anne|Perret, Christine|Coulouarn, Cedric|Clem | ||||||||||
| PMID: | 27191501 | ||||||||||
| 12. | |||||||||||
| Journal: | Int J Biochem Cell Biol. 2016 Dec;81(Pt A):195-207. | ||||||||||
| Title: | Fibrous nests in human hepatocellular carcinoma express a Wnt-induced gene signature associated with poor clinical outcome. | ||||||||||
| Author: | Desert, Romain|Mebarki, Sihem|Desille, Mireille|Sicard, Marie|Lavergne, Elise|Renaud, Stephanie|Bergeat, Damien|Sulpice, Laurent|Perret, Christine|Turlin, Bruno|Clement, Bruno|Musso, Orlando | ||||||||||
| PMID: | 27545991 | ||||||||||
| 13. | |||||||||||
| Journal: | Neoplasma. 2017;64(1):81-91. | ||||||||||
| Title: | miR-33a expression sensitizes Lgr5+ HCC-CSCs to doxorubicin via ABCA1. | ||||||||||
| Author: | Hou, H|Kang, Y|Li, Y|Zeng, Y|Ding, G|Shang, J | ||||||||||
| PMID: | 27881008 | ||||||||||
| 14. | |||||||||||
| Journal: | Oncotarget. 2017 Jun 13;8(24):39430-39442. | ||||||||||
| Title: | Dishevelled-3 phosphorylation is governed by HIPK2/PP1Calpha/ITCH axis and the non-phosphorylated form promotes cancer stemness via LGR5 in hepatocellular carcinoma. | ||||||||||
| Author: | Tsui, Yu-Man|Sze, Karen Man-Fong|Tung, Edmund Kwok-Kwan|Ho, Daniel Wai-Hung|Lee, Terence Kin-Wah|Ng, Irene Oi-Lin | ||||||||||
| PMID: | 28455968 | ||||||||||
| 15. | |||||||||||
| Journal: | Oncotarget. 2017 Feb 7;8(31):50896-50903. | ||||||||||
| Title: | LGR5 promotes hepatocellular carcinoma metastasis through inducting epithelial-mesenchymal transition. | ||||||||||
| Author: | Liu, Jie|Yu, Guo-Zheng|Cheng, Xiao-Ke|Li, Xiao-Dong|Zeng, Xian-Tao|Ren, Xue-Qun | ||||||||||
| PMID: | 28881613 | ||||||||||
| 16. | |||||||||||
| Journal: | Int J Mol Med. 2018 Aug;42(2):713-725. | ||||||||||
| Title: | Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review). | ||||||||||
| Author: | Katoh, Masaru | ||||||||||
| PMID: | 29786110 | ||||||||||
| 17. | |||||||||||
| Journal: | Mol Med Rep. 2018 Aug;18(2):2269-2276. | ||||||||||
| Title: | LncRNA CASC15 promotes colon cancer cell proliferation and metastasis by regulating the miR4310/LGR5/Wnt/betacatenin signaling pathway. | ||||||||||
| Author: | Jing, Niancai|Huang, Tao|Guo, Huaiyu|Yang, Jili|Li, Mingjing|Chen, Zhuo|Zhang, Yue | ||||||||||
| PMID: | 29956772 | ||||||||||
| 18. | |||||||||||
| Journal: | Saudi J Biol Sci. 2018 Jul;25(5):904-908. | ||||||||||
| Title: | Overexpression of leucine-rich repeat-containing G protein-coupled receptor 5 predicts poor prognosis in hepatocellular carcinoma. | ||||||||||
| Author: | Chen, Wanyuan|Fu, Qihan|Fang, Francia|Fang, Jin|Zhang, Qi|Hong, Yupeng | ||||||||||
| PMID: | 30108439 | ||||||||||
| 19. | |||||||||||
| Journal: | Am J Pathol. 2018 Sep 8. pii: S0002-9440(17)31145-8. | ||||||||||
| Title: | High Frequency of beta-Catenin Mutations in Mouse Hepatocellular Carcinomas Induced by a Nongenotoxic Constitutive Androstane Receptor Agonist. | ||||||||||
| Author: | Mattu, Sandra|Saliba, Christian|Sulas, Pia|Zavattari, Patrizia|Perra, Andrea|Kowalik, Marta A|Monga, Satdarshan P|Columbano, Amedeo | ||||||||||
| PMID: | 30201494 | ||||||||||
| 20. | |||||||||||
| Journal: | Mol Cancer Res. 2018 Sep 26. pii: 1541-7786.MCR-18-0054. | ||||||||||
| Title: | Oncogenic STRAP Supports Hepatocellular Carcinoma Growth by Enhancing Wnt/beta-Catenin Signaling. | ||||||||||
| Author: | Wang, Wenhui|Li, Shan|Liu, Pengyu|Sideras, Kostandinos|van de Werken, Harmen J G|van der Heide, Marieke|Cao, Wanlu|Lavrijsen, Marla|Peppelenbosch, Maikel P|Bruno, Marco|Pan, Qiuwei|Smits, Ron | ||||||||||
| PMID: | 30257989 | ||||||||||
| 21. | |||||||||||
| Journal: | Zhonghua Yi Xue Za Zhi. 2018 Sep 25;98(36):2899-2904. | ||||||||||
| Title: | [Expression of stem cell markers CD44 and Lgr5 in colorectal cancer and its relationship with lymph node and liver metastasis]. | ||||||||||
| Author: | Wang, X F|Zhang, X L|Xu, L P|Shi, G G|Zheng, H Y|Sun, B C | ||||||||||
| PMID: | 30293346 | ||||||||||