Literatures

Primary Site >> Colorectal Cancer

Gene >> LGR5

1.
Journal:	Cancer Biol Ther. 2006 Apr;5(4):419-26. Epub 2006 Apr 19.
Title:	Identification of overexpression of orphan G protein-coupled receptor GPR49 in human colon and ovarian primary tumors.
Author:	McClanahan, Terrill\|Koseoglu, Sandra\|Smith, Kathleen\|Grein, Jeffrey\|Gustafson, Eric\|Black, Stuart\|Kirschmeier, Paul\|Samatar, Ahmed A
PMID:	16575208

2.
Journal:	Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13427-32.
Title:	Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity.
Author:	Vermeulen, L\|Todaro, M\|de Sousa Mello, F\|Sprick, M R\|Kemper, K\|Perez Alea, M\|Richel, D J\|Stassi, G\|Medema, J P
PMID:	18765800

3.
Journal:	ScientificWorldJournal. 2008 Nov 23;8:1168-76.
Title:	Immunostaining of Lgr5, an intestinal stem cell marker, in normal and premalignant human gastrointestinal tissue.
Author:	Becker, Laren\|Huang, Qin\|Mashimo, Hiroshi
PMID:	19030762

4.
Journal:	Annu Rev Physiol. 2009;71:241-60.
Title:	Stem cells, self-renewal, and differentiation in the intestinal epithelium.
Author:	van der Flier, Laurens G\|Clevers, Hans
PMID:	18808327

5.
Journal:	J Clin Invest. 2009 Sep;119(9):2691-701.
Title:	Inactivating cholecystokinin-2 receptor inhibits progastrin-dependent colonic crypt fission, proliferation, and colorectal cancer in mice.
Author:	Jin, Guangchun\|Ramanathan, Vigneshwaran\|Quante, Michael\|Baik, Gwang Ho\|Yang, Xiangdong\|Wang, Sophie S W\|Tu, Shuiping\|Gordon, Shanisha A K\|Pritchard, David Mark\|Varro, Andrea\|Shulkes, Arthur\|Wang, Timothy C
PMID:	19652364

6.
Journal:	Curr Colorectal Cancer Rep. 2009 Oct 1;5(4):209.
Title:	New Therapeutics Targeting Colon Cancer Stem Cells.
Author:	Thenappan, Arun\|Li, Ying\|Shetty, Kirti\|Johnson, Lynt\|Reddy, E P\|Mishra, Lopa
PMID:	20148131

7.
Journal:	Dis Esophagus. 2010 Feb;23(2):168-74.
Title:	Lgr5, an intestinal stem cell marker, is abnormally expressed in Barrett's esophagus and esophageal adenocarcinoma.
Author:	Becker, L\|Huang, Q\|Mashimo, H
PMID:	19549212

8.
Journal:	Carcinogenesis. 2010 Jun;31(6):1003-9.
Title:	Establishment and characterization of 13 human colorectal carcinoma cell lines: mutations of genes and expressions of drug-sensitivity genes and cancer stem cell markers.
Author:	Ku, Ja-Lok\|Shin, Young-Kyoung\|Kim, Duck-Woo\|Kim, Kyung-Hee\|Choi, Jin-Sung\|Hong, Sung-Hye\|Jeon, You-Kyung\|Kim, Sung-Hee\|Kim, Hong-Sun\|Park, Jae-Hyun\|Kim, Il-Jin\|Park, Jae-Gahb
PMID:	20176655

9.
Journal:	Int J Colorectal Dis. 2010 May;25(5):583-90.
Title:	Expression of Lgr5 in human colorectal carcinogenesis and its potential correlation with beta-catenin.
Author:	Fan, Xiang-Shan\|Wu, Hong-Yan\|Yu, Hui-Ping\|Zhou, Qiang\|Zhang, Yi-Fen\|Huang, Qin
PMID:	20195621

10.
Journal:	Cancer Sci. 2010 Jul;101(7):1731-7.
Title:	Overexpression of leucine-rich repeat-containing G protein-coupled receptor 5 in colorectal cancer.
Author:	Uchida, Hiroshi\|Yamazaki, Ken\|Fukuma, Mariko\|Yamada, Taketo\|Hayashida, Tetsu\|Hasegawa, Hirotoshi\|Kitajima, Masaki\|Kitagawa, Yuko\|Sakamoto, Michiie
PMID:	20384634

11.
Journal:	Gastroenterology. 2010 May;138(5):1681-96.
Title:	Leucine-rich repeat-containing G-protein-coupled receptors as markers of adult stem cells.
Author:	Barker, Nick\|Clevers, Hans
PMID:	20417836

12.
Journal:	Gastroenterology. 2010 Jun;138(6):2151-62.
Title:	Colon cancer stem cells: promise of targeted therapy.
Author:	Todaro, Matilde\|Francipane, Maria Giovanna\|Medema, Jan Paul\|Stassi, Giorgio
PMID:	20420952

13.
Journal:	Gut. 2010 Sep;59(9):1236-44.
Title:	Expression of an ASCL2 related stem cell signature and IGF2 in colorectal cancer liver metastases with 11p15.5 gain.
Author:	Stange, D E\|Engel, F\|Longerich, T\|Koo, B K\|Koch, M\|Delhomme, N\|Aigner, M\|Toedt, G\|Schirmacher, P\|Lichter, P\|Weitz, J\|Radlwimmer, B
PMID:	20479215

14.
Journal:	Mol Cancer. 2010 Aug 6;9:212.
Title:	The Wnt/beta-catenin pathway regulates growth and maintenance of colonospheres.
Author:	Kanwar, Shailender S\|Yu, Yingjie\|Nautiyal, Jyoti\|Patel, Bhaumik B\|Majumdar, Adhip P N
PMID:	20691072

15.
Journal:	Gastroenterology. 2010 Dec;139(6):2072-2082.e5.
Title:	Characterization of the intestinal cancer stem cell marker CD166 in the human and mouse gastrointestinal tract.
Author:	Levin, Trevor G\|Powell, Anne E\|Davies, Paige S\|Silk, Alain D\|Dismuke, Adria D\|Anderson, Eric C\|Swain, John R\|Wong, Melissa H
PMID:	20826154

16.
Journal:	Oncotarget. 2010 Oct;1(6):387-95.
Title:	Molecular identification and targeting of colorectal cancer stem cells.
Author:	Kemper, Kristel\|Grandela, Catarina\|Medema, Jan Paul
PMID:	21311095

17.
Journal:	Ann Surg Oncol. 2011 Apr;18(4):1166-74.
Title:	Significance of Lgr5(+ve) cancer stem cells in the colon and rectum.
Author:	Takahashi, Hidekazu\|Ishii, Hideshi\|Nishida, Naohiro\|Takemasa, Ichiro\|Mizushima, Tsunekazu\|Ikeda, Masataka\|Yokobori, Takehiko\|Mimori, Koshi\|Yamamoto, Hirofumi\|Sekimoto, Mitsugu\|Doki, Yuichiro\|Mori, Masaki
PMID:	21125339

18.
Journal:	Front Biosci (Landmark Ed). 2011 Jan 1;16:1651-62.
Title:	Colon cancer stem cells: implications in carcinogenesis.
Author:	Sanders, Matthew A\|Majumdar, Adhip P N
PMID:	21196254

19.
Journal:	Nature. 2011 Jan 13;469(7329):231-5.
Title:	c-Jun N-terminal phosphorylation antagonises recruitment of the Mbd3/NuRD repressor complex.
Author:	Aguilera, Cristina\|Nakagawa, Kentaro\|Sancho, Rocio\|Chakraborty, Atanu\|Hendrich, Brian\|Behrens, Axel
PMID:	21196933

20.
Journal:	Anticancer Res. 2011 Jan;31(1):263-70.
Title:	Expression of LGR5, an intestinal stem cell marker, during each stage of colorectal tumorigenesis.
Author:	Takeda, Kayoko\|Kinoshita, Ichiro\|Shimizu, Yasushi\|Matsuno, Yoshihiro\|Shichinohe, Toshiaki\|Dosaka-Akita, Hirotoshi
PMID:	21273608

21.
Journal:	Nat Rev Gastroenterol Hepatol. 2011 Feb;8(2):90-100.
Title:	Stem cells and their implications for colorectal cancer.
Author:	Zeki, Sebastian S\|Graham, Trevor A\|Wright, Nicholas A
PMID:	21293509

22.
Journal:	World J Gastroenterol. 2011 Feb 21;17(7):932-7.
Title:	Upregulated CD133 expression in tumorigenesis of colon cancer cells.
Author:	Yang, Zhi-Li\|Zheng, Qi\|Yan, Jun\|Pan, Ye\|Wang, Zhi-Gang
PMID:	21412503

23.
Journal:	Cell Stem Cell. 2011 May 6;8(5):511-24.
Title:	The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapse.
Author:	Merlos-Suarez, Anna\|Barriga, Francisco M\|Jung, Peter\|Iglesias, Mar\|Cespedes, Maria Virtudes\|Rossell, David\|Sevillano, Marta\|Hernando-Momblona, Xavier\|da Silva-Diz, Victoria\|Munoz, Purificacion\|Clevers, Hans\|Sancho, Elena\|Mangues, Ramon\|Batlle, Eduard
PMID:	21419747

24.
Journal:	Am J Pathol. 2011 Apr;178(4):1805-13.
Title:	Cytotoxic T lymphocytes efficiently recognize human colon cancer stem-like cells.
Author:	Inoda, Satoko\|Hirohashi, Yoshihiko\|Torigoe, Toshihiko\|Morita, Rena\|Takahashi, Akari\|Asanuma, Hiroko\|Nakatsugawa, Munehide\|Nishizawa, Satoshi\|Tamura, Yasuaki\|Tsuruma, Tetsuhiro\|Terui, Takeshi\|Kondo, Toru\|Ishitani, Kunihiko\|Hasegawa, Tadashi\|Hirata, Koichi\|
PMID:	21435460

25.
Journal:	Pathology. 2011 Apr;43(3):220-7.
Title:	A gene signature distinguishing CD133hi from CD133- colorectal cancer cells: essential role for EGR1 and downstream factors.
Author:	Ernst, Aurelie\|Aigner, Maximilian\|Nakata, Susumu\|Engel, Felix\|Schlotter, Magdalena\|Kloor, Matthias\|Brand, Karsten\|Schmitt, Steffen\|Steinert, Gunnar\|Rahbari, Nuh\|Koch, Moritz\|Radlwimmer, Bernhard\|Weitz, Jurgen\|Lichter, Peter
PMID:	21436631

26.
Journal:	Cancer Res. 2011 Jun 15;71(12):4260-8.
Title:	LIN28B promotes colon cancer progression and metastasis.
Author:	King, Catrina E\|Cuatrecasas, Miriam\|Castells, Antoni\|Sepulveda, Antonia R\|Lee, Ju-Seog\|Rustgi, Anil K
PMID:	21512136

27.
Journal:	Int J Clin Exp Pathol. 2011 Apr;4(4):327-35. Epub 2011 Apr 25.
Title:	Expression of the adult intestinal stem cell marker Lgr5 in the metastatic cascade of colorectal cancer.
Author:	Kleist, Britta\|Xu, Li\|Li, Guojun\|Kersten, Christian
PMID:	21577318

28.
Journal:	Gut. 2011 Dec;60(12):1703-11.
Title:	Type 2 diabetes risk variants and colorectal cancer risk: the Multiethnic Cohort and PAGE studies.
Author:	Cheng, Iona\|Caberto, Christian P\|Lum-Jones, Annette\|Seifried, Ann\|Wilkens, Lynne R\|Schumacher, Fredrick R\|Monroe, Kristine R\|Lim, Unhee\|Tiirikainen, Maarit\|Kolonel, Laurence N\|Henderson, Brian E\|Stram, Daniel O\|Haiman, Christopher A\|Le Marchand, Loic
PMID:	21602532

29.
Journal:	Oncogene. 2011 Oct 6;30(40):4185-93.
Title:	LIN28B fosters colon cancer migration, invasion and transformation through let-7-dependent and -independent mechanisms.
Author:	King, C E\|Wang, L\|Winograd, R\|Madison, B B\|Mongroo, P S\|Johnstone, C N\|Rustgi, A K
PMID:	21625210

30.
Journal:	PLoS One. 2011;6(7):e22733.
Title:	LGR5 is a negative regulator of tumourigenicity, antagonizes Wnt signalling and regulates cell adhesion in colorectal cancer cell lines.
Author:	Walker, Francesca\|Zhang, Hui-Hua\|Odorizzi, Annalisa\|Burgess, Antony W
PMID:	21829496

31.
Journal:	Clin Cancer Res. 2011 Nov 1;17(21):6934-43.
Title:	Common cancer stem cell gene variants predict colon cancer recurrence.
Author:	Gerger, Armin\|Zhang, Wu\|Yang, Dongyun\|Bohanes, Pierre\|Ning, Yan\|Winder, Thomas\|LaBonte, Melissa J\|Wilson, Peter M\|Benhaim, Leonor\|Paez, David\|El-Khoueiry, Rita\|El-Khoueiry, Anthony\|Kahn, Michael\|Lenz, Heinz-Josef
PMID:	21918173

32.
Journal:	BMC Cancer. 2011 Oct 6;11:429.
Title:	A novel splice variant of the stem cell marker LGR5/GPR49 is correlated with the risk of tumor-related death in soft-tissue sarcoma patients.
Author:	Rot, Swetlana\|Taubert, Helge\|Bache, Matthias\|Greither, Thomas\|Wurl, Peter\|Eckert, Alexander W\|Schubert, Johannes\|Vordermark, Dirk\|Kappler, Matthias
PMID:	21978106

33.
Journal:	Stem Cells. 2011 Dec;29(12):2042-50.
Title:	Myb controls intestinal stem cell genes and self-renewal.
Author:	Cheasley, Dane\|Pereira, Lloyd\|Lightowler, Sally\|Vincan, Elizabeth\|Malaterre, Jordane\|Ramsay, Robert G
PMID:	21997934

34.
Journal:	Cell Stem Cell. 2011 Nov 4;9(5):476-85.
Title:	Methylation of cancer-stem-cell-associated Wnt target genes predicts poor prognosis in colorectal cancer patients.
Author:	de Sousa E Melo, Felipe\|Colak, Selcuk\|Buikhuisen, Joyce\|Koster, Jan\|Cameron, Kate\|de Jong, Joan H\|Tuynman, Jurriaan B\|Prasetyanti, Pramudita R\|Fessler, Evelyn\|van den Bergh, Saskia P\|Rodermond, Hans\|Dekker, Evelien\|van der Loos, Chris M\|Pals, Steven T\|van
PMID:	22056143

35.
Journal:	Cancer Sci. 2012 Apr;103(4):828-35.
Title:	Dickkopf-1 inhibits epithelial-mesenchymal transition of colon cancer cells and contributes to colon cancer suppression.
Author:	Qi, Lisha\|Sun, Baocun\|Liu, Zhiyong\|Li, Hui\|Gao, Jun\|Leng, Xue
PMID:	22321022

36.
Journal:	Dig Dis Sci. 2012 Jul;57(7):1866-74.
Title:	High-fat diet alters gene expression in the liver and colon: links to increased development of aberrant crypt foci.
Author:	Padidar, Sara\|Farquharson, Andrew J\|Williams, Lynda M\|Kearney, Rebecca\|Arthur, John R\|Drew, Janice E
PMID:	22373862

37.
Journal:	PLoS One. 2012;7(2):e32170.
Title:	Ascl2 knockdown results in tumor growth arrest by miRNA-302b-related inhibition of colon cancer progenitor cells.
Author:	Zhu, Rong\|Yang, Yongtao\|Tian, Yin\|Bai, Jianying\|Zhang, Xin\|Li, Xiaohuan\|Peng, Zhihong\|He, Yonghong\|Chen, Lei\|Pan, Qiong\|Fang, Dianchun\|Chen, Wensheng\|Qian, Chen\|Bian, Xiuwu\|Wang, Rongquan
PMID:	22384170

38.
Journal:	Cancer Invest. 2012 May;30(4):275-86.
Title:	P53 gene mutation increases progastrin dependent colonic proliferation and colon cancer formation in mice.
Author:	Ramanathan, Vigneshwaran\|Jin, Guangchun\|Westphalen, Christoph Benedikt\|Whelan, Ashley\|Dubeykovskiy, Alexander\|Takaishi, Shigeo\|Wang, Timothy C
PMID:	22480191

39.
Journal:	Int J Oncol. 2012 Jul;41(1):285-91.
Title:	Use of multiple biomarkers for the localization and characterization of colon cancer stem cells by indirect immunocytochemistry.
Author:	Amsterdam, Abraham\|Raanan, Calanit\|Schreiber, Letizia\|Freyhan, Ora\|Fabrikant, Yakov\|Melzer, Ehud
PMID:	22504585

40.
Journal:	Int J Mol Sci. 2012;13(4):4367-87.
Title:	Evaluation of the adenocarcinoma-associated gene AGR2 and the intestinal stem cell marker LGR5 as biomarkers in colorectal cancer.
Author:	Valladares-Ayerbes, Manuel\|Blanco-Calvo, Moises\|Reboredo, Margarita\|Lorenzo-Patino, Maria J\|Iglesias-Diaz, Pilar\|Haz, Mar\|Diaz-Prado, Silvia\|Medina, Vanessa\|Santamarina, Isabel\|Pertega, Sonia\|Figueroa, Angelica\|Anton-Aparicio, Luis M
PMID:	22605983

41.
Journal:	PLoS One. 2012;7(5):e37137.
Title:	LGR6 is a high affinity receptor of R-spondins and potentially functions as a tumor suppressor.
Author:	Gong, Xing\|Carmon, Kendra S\|Lin, Qiushi\|Thomas, Anthony\|Yi, Jing\|Liu, Qingyun
PMID:	22615920

42.
Journal:	EMBO J. 2012 Jun 13;31(12):2685-96.
Title:	Adult mammalian stem cells: the role of Wnt, Lgr5 and R-spondins.
Author:	Schuijers, Jurian\|Clevers, Hans
PMID:	22617424

43.
Journal:	Oncol Rep. 2012 Sep;28(3):855-61.
Title:	Gene expression profiles of tumor regression grade in locally advanced rectal cancer after neoadjuvant chemoradiotherapy.
Author:	Saigusa, Susumu\|Tanaka, Koji\|Toiyama, Yuji\|Matsushita, Kohei\|Kawamura, Mikio\|Okugawa, Yoshinaga\|Hiro, Junichiro\|Inoue, Yasuhiro\|Uchida, Keiichi\|Mohri, Yasuhiko\|Kusunoki, Masato
PMID:	22711167

44.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2012 Aug 15;303(4):G443-52.
Title:	CD24 can be used to isolate Lgr5+ putative colonic epithelial stem cells in mice.
Author:	King, Jeffrey B\|von Furstenberg, Richard J\|Smith, Brian J\|McNaughton, Kirk K\|Galanko, Joseph A\|Henning, Susan J
PMID:	22723265

45.
Journal:	Nature. 2012 Aug 30;488(7413):665-9.
Title:	Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors.
Author:	Koo, Bon-Kyoung\|Spit, Maureen\|Jordens, Ingrid\|Low, Teck Y\|Stange, Daniel E\|van de Wetering, Marc\|van Es, Johan H\|Mohammed, Shabaz\|Heck, Albert J R\|Maurice, Madelon M\|Clevers, Hans
PMID:	22895187

46.
Journal:	Int J Oncol. 2012 Nov;41(5):1744-50.
Title:	Induction of LGR5 by H2O2 treatment is associated with cell proliferation via the JNK signaling pathway in colon cancer cells.
Author:	Kim, Sung-Hee\|Kim, Kyung-Hee\|Yoo, Byong-Chul\|Ku, Ja-Lok
PMID:	22923033

47.
Journal:	Int J Oncol. 2012 Nov;41(5):1643-52.
Title:	Clinical significance of LGR5 and CD44 expression in locally advanced rectal cancer after preoperative chemoradiotherapy.
Author:	Saigusa, Susumu\|Inoue, Yasuhiro\|Tanaka, Koji\|Toiyama, Yuji\|Matsushita, Kohei\|Kawamura, Mikio\|Okugawa, Yoshinaga\|Hiro, Junichiro\|Uchida, Keiichi\|Mohri, Yasuhiko\|Kusunoki, Masato
PMID:	22923071

48.
Journal:	Cell Prolif. 2012 Oct;45(5):413-9.
Title:	EGF signalling pathway regulates colon cancer stem cell proliferation and apoptosis.
Author:	Feng, Y\|Dai, X\|Li, X\|Wang, H\|Liu, J\|Zhang, J\|Du, Y\|Xia, L
PMID:	22925500

49.
Journal:	Am J Transl Res. 2012;4(3):279-90. Epub 2012 Jul 20.
Title:	Single nucleotide polymorphisms of the adult intestinal stem cell marker Lgr5 in primary and metastatic colorectal cancer.
Author:	Kleist, Britta\|Xu, Li\|Kersten, Christian\|Seel, Violetta\|Li, Guojun\|Poetsch, Micaela
PMID:	22937206

50.
Journal:	Stem Cells. 2012 Nov;30(11):2378-86.
Title:	Monoclonal antibodies against Lgr5 identify human colorectal cancer stem cells.
Author:	Kemper, Kristel\|Prasetyanti, Pramudita R\|De Lau, Wim\|Rodermond, Hans\|Clevers, Hans\|Medema, Jan Paul
PMID:	22969042

51.
Journal:	Stem Cells. 2012 Dec;30(12):2631-44.
Title:	LGR5-positive colon cancer stem cells interconvert with drug-resistant LGR5-negative cells and are capable of tumor reconstitution.
Author:	Kobayashi, Shinta\|Yamada-Okabe, Hisafumi\|Suzuki, Masami\|Natori, Osamu\|Kato, Atsuhiko\|Matsubara, Koichi\|Jau Chen, Yu\|Yamazaki, Masaki\|Funahashi, Shinichi\|Yoshida, Kenji\|Hashimoto, Eri\|Watanabe, Yoshinori\|Mutoh, Hironori\|Ashihara, Motooki\|Kato, Chie\|Watanab
PMID:	23081779

52.
Journal:	World J Surg Oncol. 2012 Nov 15;10:244.
Title:	Lgr5 is a potential marker of colorectal carcinoma stem cells that correlates with patient survival.
Author:	Wu, Xiao-Song\|Xi, Hong-Qing\|Chen, Lin
PMID:	23153436

53.
Journal:	Gut. 2013 Jul;62(7):1012-23.
Title:	In situ validation of an intestinal stem cell signature in colorectal cancer.
Author:	Ziskin, Jennifer L\|Dunlap, Debra\|Yaylaoglu, Murat\|Fodor, Imola K\|Forrest, William F\|Patel, Rajesh\|Ge, Nianfeng\|Hutchins, Gordon G\|Pine, James K\|Quirke, Philip\|Koeppen, Hartmut\|Jubb, Adrian M
PMID:	22637696

54.
Journal:	Clin Exp Metastasis. 2013 Feb;30(2):189-200.
Title:	Transcriptional profiling identifies genes induced by hepatocyte-derived extracellular matrix in metastatic human colorectal cancer cell lines.
Author:	Zvibel, Isabel\|Wagner, Adam\|Pasmanik-Chor, Metsada\|Varol, Chen\|Oron-Karni, Varda\|Santo, Erwin M\|Halpern, Zamir\|Kariv, Revital
PMID:	22930170

55.
Journal:	J Cancer Res Clin Oncol. 2013 Jan;139(1):131-8.
Title:	Significant correlation between LKB1 and LGR5 gene expression and the association with poor recurrence-free survival in rectal cancer after preoperative chemoradiotherapy.
Author:	Saigusa, Susumu\|Inoue, Yasuhiro\|Tanaka, Koji\|Toiyama, Yuji\|Kawamura, Mikio\|Okugawa, Yoshinaga\|Okigami, Masato\|Hiro, Junichiro\|Uchida, Keiichi\|Mohri, Yasuhiko\|Kusunoki, Masato
PMID:	22986809

56.
Journal:	Acta Histochem. 2013 May;115(4):320-9.
Title:	Differential localization of LGR5 and Nanog in clusters of colon cancer stem cells.
Author:	Amsterdam, Abraham\|Raanan, Calanit\|Schreiber, Letizia\|Freyhan, Ora\|Fabrikant, Yakov\|Melzer, Ehud\|Givol, David
PMID:	23098761

57.
Journal:	Gastroenterology. 2013 Feb;144(2):381-91.
Title:	Troy, a tumor necrosis factor receptor family member, interacts with lgr5 to inhibit wnt signaling in intestinal stem cells.
Author:	Fafilek, Bohumil\|Krausova, Michaela\|Vojtechova, Martina\|Pospichalova, Vendula\|Tumova, Lucie\|Sloncova, Eva\|Huranova, Martina\|Stancikova, Jitka\|Hlavata, Adela\|Svec, Jiri\|Sedlacek, Radislav\|Luksan, Ondrej\|Oliverius, Martin\|Voska, Ludek\|Jirsa, Milan\|Paces, Ja
PMID:	23142137

58.
Journal:	Cancer Invest. 2013 Feb;31(2):97-102.
Title:	Celecoxib downregulates CD133 expression through inhibition of the Wnt signaling pathway in colon cancer cells.
Author:	Deng, Yanhong\|Su, Qiao\|Mo, Jianwen\|Fu, Xinhui\|Zhang, Yan\|Lin, Edward H
PMID:	23245395

59.
Journal:	Hepatol Res. 2013 Jan;43(1):84-90.
Title:	Leucine-rich repeat-containing G protein-coupled receptor 5 expression in ductular reactions after chemotherapy for metastatic colorectal cancer.
Author:	Saigusa, Susumu\|Tanaka, Koji\|Toiyama, Yuji\|Matsushita, Kohei\|Kawamura, Mikio\|Okugawa, Yoshinaga\|Uchida, Keiichi\|Inoue, Yasuhiro\|Mohri, Yasuhiko\|Kusunoki, Masato
PMID:	23332089

60.
Journal:	Biochem Biophys Res Commun. 2013 Mar 1;432(1):175-81.
Title:	The acquisition of malignant potential in colon cancer is regulated by the stabilization of Atonal homolog 1 protein.
Author:	Kano, Yoshihito\|Tsuchiya, Kiichiro\|Zheng, Xiu\|Horita, Nobukatsu\|Fukushima, Keita\|Hibiya, Shuji\|Yamauchi, Yuhki\|Nishimura, Tatsunori\|Hinohara, Kunihiko\|Gotoh, Noriko\|Suzuki, Shinji\|Okamoto, Ryuichi\|Nakamura, Tetsuya\|Watanabe, Mamoru
PMID:	23333391

61.
Journal:	Carcinogenesis. 2013 May;34(5):1150-7.
Title:	LGR5 promotes survival in human colorectal adenoma cells and is upregulated by PGE2: implications for targeting adenoma stem cells with NSAIDs.
Author:	Al-Kharusi, Manal R A\|Smartt, Helena J M\|Greenhough, Alexander\|Collard, Tracey J\|Emery, Elizabeth D\|Williams, Ann C\|Paraskeva, Chris
PMID:	23349017

62.
Journal:	Pathol Int. 2013 Jan;63(1):13-9.
Title:	Overexpression of leucine-rich repeat-containing G protein-coupled receptor 5 in gastric cancer.
Author:	Yamanoi, Kazuhiro\|Fukuma, Mariko\|Uchida, Hiroshi\|Kushima, Ryoji\|Yamazaki, Ken\|Katai, Hitoshi\|Kanai, Yae\|Sakamoto, Michiie
PMID:	23356221

63.
Journal:	Gastroenterology. 2013 May;144(5):1001-11.
Title:	Foxf2 in intestinal fibroblasts reduces numbers of Lgr5(+) stem cells and adenoma formation by inhibiting Wnt signaling.
Author:	Nik, Ali Moussavi\|Reyahi, Azadeh\|Ponten, Fredrik\|Carlsson, Peter
PMID:	23376422

64.
Journal:	PLoS One. 2013;8(2):e56082.
Title:	Kruppel-like factor 4 acts as an oncogene in colon cancer stem cell-enriched spheroid cells.
Author:	Leng, Zhengwei\|Tao, Kaixiong\|Xia, Qinghua\|Tan, Jun\|Yue, Zhongyi\|Chen, Jinhuang\|Xi, Hailin\|Li, Jie\|Zheng, Hai
PMID:	23418515

65.
Journal:	Cell Biol Int. 2013 May;37(5):406-14.
Title:	Intestinal stem cells - types and markers.
Author:	Zhang, Zhigang\|Huang, Jian
PMID:	23471862

66.
Journal:	Acta Histochem. 2013 Sep;115(7):770-1.
Title:	Re: (1) "differential localization of LGR5 and Nanog in clusters of colon cancer stem cells" by Amsterdam A, Raanan C, Schreiber L, Freyhan O, Fabrikant Y, Melzer E, Givol D [Acta Histochem. (2012, October 23), pii: S0065-1281(12)00112-2] and (2) "localiz
Author:	Wright, Nicholas
PMID:	23522104

67.
Journal:	Evid Based Complement Alternat Med. 2013;2013:702869.
Title:	Methanolic extracts of bitter melon inhibit colon cancer stem cells by affecting energy homeostasis and autophagy.
Author:	Kwatra, Deep\|Subramaniam, Dharmalingam\|Ramamoorthy, Prabhu\|Standing, David\|Moran, Elizabeth\|Velayutham, Ravichandiran\|Mitra, Ashim\|Umar, Shahid\|Anant, Shrikant
PMID:	23533514

68.
Journal:	Front Oncol. 2013 Apr 15;3:81.
Title:	LGR5 is Expressed by Ewing Sarcoma and Potentiates Wnt/beta-Catenin Signaling.
Author:	Scannell, Christopher A\|Pedersen, Elisabeth A\|Mosher, Jack T\|Krook, Melanie Anne\|Nicholls, Lauren A\|Wilky, Breelyn A\|Loeb, David M\|Lawlor, Elizabeth R
PMID:	23596566

69.
Journal:	J Mol Med (Berl). 2013 Aug;91(8):989-1000.
Title:	MiR-142-3p functions as a tumor suppressor by targeting CD133, ABCG2, and Lgr5 in colon cancer cells.
Author:	Shen, Wei-Wei\|Zeng, Zhi\|Zhu, Wen-Xia\|Fu, Guo-Hui
PMID:	23619912

70.
Journal:	Cancer Lett. 2013 Aug 9;336(1):174-84.
Title:	IFN-gamma selectively exerts pro-apoptotic effects on tumor-initiating label-retaining colon cancer cells.
Author:	Ni, Chao\|Wu, Ping\|Zhu, Xiaotao\|Ye, Jun\|Zhang, Zhigang\|Chen, Zhigang\|Zhang, Ting\|Zhang, Tao\|Wang, Ke\|Wu, Dang\|Qiu, Fuming\|Huang, Jian
PMID:	23643941

71.
Journal:	Cell Stem Cell. 2013 Jun 6;12(6):761-73.
Title:	ROS production and NF-kappaB activation triggered by RAC1 facilitate WNT-driven intestinal stem cell proliferation and colorectal cancer initiation.
Author:	Myant, Kevin B\|Cammareri, Patrizia\|McGhee, Ewan J\|Ridgway, Rachel A\|Huels, David J\|Cordero, Julia B\|Schwitalla, Sarah\|Kalna, Gabriela\|Ogg, Erinn-Lee\|Athineos, Dimitris\|Timpson, Paul\|Vidal, Marcos\|Murray, Graeme I\|Greten, Florian R\|Anderson, Kurt I\|Sansom,
PMID:	23665120

72.
Journal:	PLoS One. 2013 May 14;8(5):e63298.
Title:	TLR4 activates the beta-catenin pathway to cause intestinal neoplasia.
Author:	Santaolalla, Rebeca\|Sussman, Daniel A\|Ruiz, Jose R\|Davies, Julie M\|Pastorini, Cristhine\|Espana, Cecilia L\|Sotolongo, John\|Burlingame, Oname\|Bejarano, Pablo A\|Philip, Sakhi\|Ahmed, Mansoor M\|Ko, Jeffrey\|Dirisina, Ramanarao\|Barrett, Terrence A\|Shang, Limin\|L
PMID:	23691015

73.
Journal:	Acta Pharmacol Sin. 2013 Jun;34(6):793-804.
Title:	Establishment of a human colorectal cancer cell line P6C with stem cell properties and resistance to chemotherapeutic drugs.
Author:	Rao, Guan-hua\|Liu, Hong-min\|Li, Bao-wei\|Hao, Jia-jie\|Yang, Yan-lei\|Wang, Ming-rong\|Wang, Xiao-hui\|Wang, Jun\|Jin, Hai-jing\|Du, Lei\|Chen, Quan
PMID:	23736004

74.
Journal:	Science. 2013 Jun 7;340(6137):1190-4.
Title:	Growing self-organizing mini-guts from a single intestinal stem cell: mechanism and applications.
Author:	Sato, Toshiro\|Clevers, Hans
PMID:	23744940

75.
Journal:	Cell Stem Cell. 2013 Jun 6;12(6):635-6.
Title:	The other face of ROS: a driver of stem cell expansion in colorectal cancer.
Author:	Pelicci, Pier Giuseppe\|Dalton, Paola\|Giorgio, Marco
PMID:	23746969

76.
Journal:	J Exp Med. 2013 Jul 1;210(7):1331-50.
Title:	AP4 is a mediator of epithelial-mesenchymal transition and metastasis in colorectal cancer.
Author:	Jackstadt, Rene\|Roh, Simone\|Neumann, Jens\|Jung, Peter\|Hoffmann, Reinhard\|Horst, David\|Berens, Christian\|Bornkamm, Georg W\|Kirchner, Thomas\|Menssen, Antje\|Hermeking, Heiko
PMID:	23752226

77.
Journal:	Int J Colorectal Dis. 2013 Nov;28(11):1535-46.
Title:	Overexpression of Lgr5 correlates with resistance to 5-FU-based chemotherapy in colorectal cancer.
Author:	Hsu, Hung-Chih\|Liu, Yi-Shiuan\|Tseng, Kai-Chi\|Hsu, Cheng-Lung\|Liang, Ying\|Yang, Tsai-Sheng\|Chen, Jinn-Shiun\|Tang, Rei-Ping\|Chen, Shu-Jen\|Chen, Hua-Chien
PMID:	23784051

78.
Journal:	Nan Fang Yi Ke Da Xue Xue Bao. 2013 Jul;33(7):972-6.
Title:	[Lgr5 and CD44 expressions in different types of intestinal polyps and colorectal cancer].
Author:	Chai, Ningli\|Zhang, Wencheng\|Wang, Yanmin\|Zhou, Zhaotao\|Zhang, Yane\|Liu, Hongyan\|Wan, Jun\|Qin, Jinhua\|Wang, Shuyong\|Wang, Yunfang\|Pei, Xuetao\|Wu, Benyan\|Linghu, Enqiang
PMID:	23895835

79.
Journal:	Toxicol Lett. 2013 Oct 24;222(2):139-45.
Title:	Salinomycin induces apoptosis in cisplatin-resistant colorectal cancer cells by accumulation of reactive oxygen species.
Author:	Zhou, Jin\|Li, Pu\|Xue, Xiaofeng\|He, Songbing\|Kuang, Yuting\|Zhao, Hong\|Chen, Shaoji\|Zhi, Qiaoming\|Guo, Xiaobo
PMID:	23916687

80.
Journal:	Oncotarget. 2013 Sep;4(9):1399-415.
Title:	Repression of c-Kit by p53 is mediated by miR-34 and is associated with reduced chemoresistance, migration and stemness.
Author:	Siemens, Helge\|Jackstadt, Rene\|Kaller, Markus\|Hermeking, Heiko
PMID:	24009080

81.
Journal:	Bioorg Med Chem Lett. 2013 Nov 1;23(21):5814-20.
Title:	Investigation of 3-aryl-pyrimido[5,4-e][1,2,4]triazine-5,7-diones as small molecule antagonists of beta-catenin/TCF transcription.
Author:	Zeller, Jorg\|Turbiak, Anjanette J\|Powelson, Ian A\|Lee, Surin\|Sun, Duxin\|Showalter, H D Hollis\|Fearon, Eric R
PMID:	24060489

82.
Journal:	Biomed Pharmacother. 2013 Oct;67(8):791-9.
Title:	Lgr5 promotes cancer stemness and confers chemoresistance through ABCB1 in colorectal cancer.
Author:	Liu, Yi-Shiuan\|Hsu, Hung-Chih\|Tseng, Kai-Chi\|Chen, Hua-Chien\|Chen, Shu-Jen
PMID:	24138824

83.
Journal:	Oncotarget. 2013 Nov;4(11):1948-62.
Title:	Selective targeting of human colon cancer stem-like cells by the mTOR inhibitor Torin-1.
Author:	Francipane, Maria Giovanna\|Lagasse, Eric
PMID:	24185040

84.
Journal:	EMBO J. 2013 Nov 27;32(23):3079-95.
Title:	SNAIL and miR-34a feed-forward regulation of ZNF281/ZBP99 promotes epithelial-mesenchymal transition.
Author:	Hahn, Stefanie\|Jackstadt, Rene\|Siemens, Helge\|Hunten, Sabine\|Hermeking, Heiko
PMID:	24185900

85.
Journal:	Anticancer Res. 2013 Nov;33(11):4855-65.
Title:	Differential expression and prognostic role of selected genes in colorectal cancer patients.
Author:	Pitule, Pavel\|Vycital, Ondrej\|Bruha, Jan\|Novak, Petr\|Hosek, Petr\|Treska, Vladislav\|Hlavata, Ivona\|Soucek, Pavel\|Kralickova, Milena\|Liska, Vaclav
PMID:	24222123

86.
Journal:	Oncogene. 2014 Jan 30;33(5):665-70.
Title:	Stem cell CD44v isoforms promote intestinal cancer formation in Apc(min) mice downstream of Wnt signaling.
Author:	Zeilstra, J\|Joosten, S P J\|van Andel, H\|Tolg, C\|Berns, A\|Snoek, M\|van de Wetering, M\|Spaargaren, M\|Clevers, H\|Pals, S T
PMID:	23318432

87.
Journal:	Carcinogenesis. 2014 Jan;35(1):237-46.
Title:	Occult progression by Apc-deficient intestinal crypts as a target for chemoprevention.
Author:	Fischer, Jared M\|Schepers, Arnout G\|Clevers, Hans\|Shibata, Darryl\|Liskay, R Michael
PMID:	23996931

88.
Journal:	Neoplasma. 2014;61(2):177-85.
Title:	Over-expression of LGR5 correlates with poor survival of colon cancer in mice as well as in patients.
Author:	Liu, Z\|Dai, W\|Jiang, L\|Cheng, Y
PMID:	24063790

89.
Journal:	Carcinogenesis. 2014 Apr;35(4):795-806.
Title:	Prolactin signaling enhances colon cancer stemness by modulating Notch signaling in a Jak2-STAT3/ERK manner.
Author:	Neradugomma, Naveen K\|Subramaniam, Dharmalingam\|Tawfik, Ossama W\|Goffin, Vincent\|Kumar, T Rajendra\|Jensen, Roy A\|Anant, Shrikant
PMID:	24265293

90.
Journal:	J Immunol. 2014 Jan 1;192(1):523-32.
Title:	Cancer-initiating cells from colorectal cancer patients escape from T cell-mediated immunosurveillance in vitro through membrane-bound IL-4.
Author:	Volonte, Andrea\|Di Tomaso, Tiziano\|Spinelli, Michela\|Todaro, Matilde\|Sanvito, Francesca\|Albarello, Luca\|Bissolati, Massimiliano\|Ghirardelli, Luca\|Orsenigo, Elena\|Ferrone, Soldano\|Doglioni, Claudio\|Stassi, Giorgio\|Dellabona, Paolo\|Staudacher, Carlo\|Parmian
PMID:	24277698

91.
Journal:	Carcinogenesis. 2014 Apr;35(4):849-58.
Title:	LGR5 positivity defines stem-like cells in colorectal cancer.
Author:	Hirsch, Daniela\|Barker, Nick\|McNeil, Nicole\|Hu, Yue\|Camps, Jordi\|McKinnon, Katherine\|Clevers, Hans\|Ried, Thomas\|Gaiser, Timo
PMID:	24282287

92.
Journal:	Br J Cancer. 2014 Jan 21;110(2):430-4.
Title:	ALDH1 is an independent prognostic factor for patients with stages II-III rectal cancer after receiving radiochemotherapy.
Author:	Deng, Y\|Zhou, J\|Fang, L\|Cai, Y\|Ke, J\|Xie, X\|Huang, Y\|Huang, M\|Wang, J
PMID:	24327017

93.
Journal:	Carcinogenesis. 2014 Mar;35(3):606-12.
Title:	Differential effects of 2- and 3-series E-prostaglandins on in vitro expansion of Lgr5+ colonic stem cells.
Author:	Fan, Yang-Yi\|Davidson, Laurie A\|Callaway, Evelyn S\|Goldsby, Jennifer S\|Chapkin, Robert S
PMID:	24336194

94.
Journal:	Nat Commun. 2014;5:3150.
Title:	The miR-363-GATA6-Lgr5 pathway is critical for colorectal tumourigenesis.
Author:	Tsuji, Shinnosuke\|Kawasaki, Yoshihiro\|Furukawa, Shiori\|Taniue, Kenzui\|Hayashi, Tomoatsu\|Okuno, Masumi\|Hiyoshi, Masaya\|Kitayama, Joji\|Akiyama, Tetsu
PMID:	24452072

95.
Journal:	Nat Commun. 2014;5:3149.
Title:	RSPO2-LGR5 signaling has tumour-suppressive activity in colorectal cancer.
Author:	Wu, Changjie\|Qiu, Sunquan\|Lu, Liting\|Zou, Jiawei\|Li, Wen-feng\|Wang, Ouchen\|Zhao, Haina\|Wang, Hongxiao\|Tang, Jiajia\|Chen, Lin\|Xu, Tao\|Sun, Zhongsheng\|Liao, Wanqin\|Luo, Guangbin\|Lu, Xincheng
PMID:	24476626

96.
Journal:	Genes Dev. 2014 Feb 15;28(4):305-16.
Title:	The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength.
Author:	de Lau, Wim\|Peng, Weng Chuan\|Gros, Piet\|Clevers, Hans
PMID:	24532711

97.
Journal:	Cancer Res. 2014 May 1;74(9):2487-98.
Title:	Curcumin promotes autophagic survival of a subset of colon cancer stem cells, which are ablated by DCLK1-siRNA.
Author:	Kantara, Carla\|O'Connell, Malaney\|Sarkar, Shubhashish\|Moya, Stephanie\|Ullrich, Robert\|Singh, Pomila
PMID:	24626093

98.
Journal:	PLoS One. 2014 Mar 20;9(3):e92317.
Title:	Integrative ChIP-seq/microarray analysis identifies a CTNNB1 target signature enriched in intestinal stem cells and colon cancer.
Author:	Watanabe, Kazuhide\|Biesinger, Jacob\|Salmans, Michael L\|Roberts, Brian S\|Arthur, William T\|Cleary, Michele\|Andersen, Bogi\|Xie, Xiaohui\|Dai, Xing
PMID:	24651522

99.
Journal:	Protein Sci. 2014 May;23(5):551-65.
Title:	Structure and function of LGR5: an enigmatic G-protein coupled receptor marking stem cells.
Author:	Kumar, Kaavya Krishna\|Burgess, Antony W\|Gulbis, Jacqueline M
PMID:	24677446

100.
Journal:	J Agric Food Chem. 2014 Apr 30;62(17):3734-41.
Title:	Chaetoglobosins from Chaetomium globosum, an endophytic fungus in Ginkgo biloba, and their phytotoxic and cytotoxic activities.
Author:	Li, He\|Xiao, Jian\|Gao, Yu-Qi\|Tang, Jiang Jiang\|Zhang, An-Ling\|Gao, Jin-Ming
PMID:	24708412

101.
Journal:	Biomed Pharmacother. 2014 Jun;68(5):507-13.
Title:	Expression of Lgr5, a marker of intestinal stem cells, in colorectal cancer and its clinicopathological significance.
Author:	He, Songbing\|Zhou, Hao\|Zhu, Xinguo\|Hu, Shuiqing\|Fei, Min\|Wan, Daiwei\|Gu, Wen\|Yang, Xiaodong\|Shi, Dongtao\|Zhou, Jian\|Zhou, Jin\|Zhu, Zheng\|Wang, Liang\|Li, Dechun\|Zhang, Yanyun
PMID:	24751002

102.
Journal:	Int J Mol Med. 2014 Jul;34(1):35-42.
Title:	LGR5 is required for the maintenance of spheroid-derived colon cancer stem cells.
Author:	Chen, Xiang\|Wei, Bo\|Han, Xiaoyan\|Zheng, Zongheng\|Huang, Jianglong\|Liu, Jianpei\|Huang, Yong\|Wei, Hongbo
PMID:	24789370

103.
Journal:	Int J Clin Exp Pathol. 2014 Mar 15;7(4):1572-9. eCollection 2014.
Title:	Lgr5 over-expression is positively related to the tumor progression and HER2 expression in stage pTNM IV colorectal cancer.
Author:	Gao, Feng-Juan\|Chen, Jie-Yu\|Wu, Hong-Yan\|Shi, Jiong\|Chen, Ming\|Fan, Xiang-Shan\|Huang, Qin
PMID:	24817953

104.
Journal:	Proc Natl Acad Sci U S A. 2014 May 27;111(21):E2229-36.
Title:	Oncogenic mutations in intestinal adenomas regulate Bim-mediated apoptosis induced by TGF-beta.
Author:	Wiener, Zoltan\|Band, Arja M\|Kallio, Pauliina\|Hogstrom, Jenny\|Hyvonen, Ville\|Kaijalainen, Seppo\|Ritvos, Olli\|Haglund, Caj\|Kruuna, Olli\|Robine, Sylvie\|Louvard, Daniel\|Ben-Neriah, Yinon\|Alitalo, Kari
PMID:	24825889

105.
Journal:	J Mol Med (Berl). 2014 Jun;92(6):571-81.
Title:	ZNF281/ZBP-99: a new player in epithelial-mesenchymal transition, stemness, and cancer.
Author:	Hahn, Stefanie\|Hermeking, Heiko
PMID:	24838609

106.
Journal:	PLoS One. 2014 Jun 12;9(6):e99091.
Title:	Establishment of highly tumorigenic human colorectal cancer cell line (CR4) with properties of putative cancer stem cells.
Author:	Rowehl, Rebecca A\|Burke, Stephanie\|Bialkowska, Agnieszka B\|Pettet, Donald W 3rd\|Rowehl, Leahana\|Li, Ellen\|Antoniou, Eric\|Zhang, Yuanhao\|Bergamaschi, Roberto\|Shroyer, Kenneth R\|Ojima, Iwao\|Botchkina, Galina I
PMID:	24921652

107.
Journal:	Nat Cell Biol. 2014 Jul;16(7):695-707.
Title:	The transcription factor GATA6 enables self-renewal of colon adenoma stem cells by repressing BMP gene expression.
Author:	Whissell, Gavin\|Montagni, Elisa\|Martinelli, Paola\|Hernando-Momblona, Xavier\|Sevillano, Marta\|Jung, Peter\|Cortina, Carme\|Calon, Alexandre\|Abuli, Anna\|Castells, Antoni\|Castellvi-Bel, Sergi\|Nacht, Ana Silvina\|Sancho, Elena\|Stephan-Otto Attolini, Camille\|Vice
PMID:	24952462

108.
Journal:	Cell Signal. 2014 Nov;26(11):2333-42.
Title:	LGR5 regulates survival through mitochondria-mediated apoptosis and by targeting the Wnt/beta-catenin signaling pathway in colorectal cancer cells.
Author:	Hsu, Hung-Chih\|Liu, Yi-Shiuan\|Tseng, Kai-Chi\|Tan, Bertrand Chin-Ming\|Chen, Shu-Jen\|Chen, Hua-Chien
PMID:	25025569

109.
Journal:	Cancer Res. 2014 Nov 1;74(21):6119-28.
Title:	Stress response protein cirp links inflammation and tumorigenesis in colitis-associated cancer.
Author:	Sakurai, Toshiharu\|Kashida, Hiroshi\|Watanabe, Tomohiro\|Hagiwara, Satoru\|Mizushima, Tsunekazu\|Iijima, Hideki\|Nishida, Naoshi\|Higashitsuji, Hiroaki\|Fujita, Jun\|Kudo, Masatoshi
PMID:	25187386

110.
Journal:	PLoS One. 2014 Sep 5;9(9):e107013.
Title:	Prognostic value of LGR5 in colorectal cancer: a meta-analysis.
Author:	Chen, Qing\|Zhang, Xin\|Li, Wei-Min\|Ji, Yu-Qiang\|Cao, Hao-Zhe\|Zheng, Pengsheng
PMID:	25192390

111.
Journal:	Endoscopy. 2014 Dec;46(12):1110-6.
Title:	In vivo imaging of Lgr5-positive cell populations using confocal laser endomicroscopy during early colon tumorigenesis.
Author:	Choi, Jin Woo\|Kim, Jun Ki\|Choi, Myunghwan\|Kim, Yi Rang\|Yun, Seok Hyun
PMID:	25216325

112.
Journal:	Nutrition. 2014 Nov-Dec;30(11-12):1242-56.
Title:	Colon carcinogenesis: influence of Western diet-induced obesity and targeting stem cells using dietary bioactive compounds.
Author:	Kasdagly, Maria\|Radhakrishnan, Sridhar\|Reddivari, Lavanya\|Veeramachaneni, D N Rao\|Vanamala, Jairam
PMID:	25280404

113.
Journal:	Stem Cell Res. 2014 Nov;13(3 Pt A):355-66.
Title:	Tripartite interactions between Wnt signaling, Notch and Myb for stem/progenitor cell functions during intestinal tumorigenesis.
Author:	Germann, Markus\|Xu, Huiling\|Malaterre, Jordane\|Sampurno, Shienny\|Huyghe, Mathilde\|Cheasley, Dane\|Fre, Silvia\|Ramsay, Robert G
PMID:	25290188

114.
Journal:	PLoS One. 2014 Nov 25;9(11):e113071.
Title:	Predictive gene signatures: molecular markers distinguishing colon adenomatous polyp and carcinoma.
Author:	Drew, Janice E\|Farquharson, Andrew J\|Mayer, Claus Dieter\|Vase, Hollie F\|Coates, Philip J\|Steele, Robert J\|Carey, Francis A
PMID:	25423035

115.
Journal:	Cell Cycle. 2014;13(22):3506-18.
Title:	Inhibition of C-terminal binding protein attenuates transcription factor 4 signaling to selectively target colon cancer stem cells.
Author:	Patel, Jagrut\|Baranwal, Somesh\|Love, Ian M\|Patel, Nirmita J\|Grossman, Steven R\|Patel, Bhaumik B
PMID:	25483087

116.
Journal:	BMC Complement Altern Med. 2014 Dec 15;14:490.
Title:	The number of intestinal bacteria is not critical for the enhancement of antitumor activity and reduction of intestinal toxicity of irinotecan by the Chinese herbal medicine PHY906 (KD018).
Author:	Lam, Wing\|Jiang, Zaoli\|Guan, Fulan\|Hu, Rong\|Liu, Shwu-Huey\|Chu, Edward\|Cheng, Yung-Chi
PMID:	25510341

117.
Journal:	Int J Mol Cell Med. 2014 Fall;3(4):216-24.
Title:	Heterogeneity of the level of activity of lgr5+ intestinal stem cells.
Author:	Moossavi, Shirin
PMID:	25635248

118.
Journal:	Curr Health Sci J. 2014 Jul-Sep;40(3):153-61.
Title:	Stem cells, colorectal cancer and cancer stem cell markers correlations.
Author:	Cherciu, Irina\|Barbalan, A\|Pirici, D\|Margaritescu, C\|Saftoiu, A
PMID:	25729599

119.
Journal:	Genom Data. 2014 Jun 14;2:212-5.
Title:	Transcriptome profiling of LGR5 positive colorectal cancer cells.
Author:	Hirsch, Daniela\|Hu, Yue\|Ried, Thomas\|Moll, Roland\|Gaiser, Timo
PMID:	26484096

120.
Journal:	Oncogene. 2015 Apr 2;34(14):1822-30.
Title:	Inhibition of intestinal tumor formation by deletion of the DNA methyltransferase 3a.
Author:	Weis, B\|Schmidt, J\|Maamar, H\|Raj, A\|Lin, H\|Toth, C\|Riedmann, K\|Raddatz, G\|Seitz, H-K\|Ho, A D\|Lyko, F\|Linhart, H G
PMID:	24837369

121.
Journal:	J Cancer Res Clin Oncol. 2015 Jan;141(1):11-21.
Title:	CBB1003, a lysine-specific demethylase 1 inhibitor, suppresses colorectal cancer cells growth through down-regulation of leucine-rich repeat-containing G-protein-coupled receptor 5 expression.
Author:	Hsu, Hung-Chih\|Liu, Yi-Shiuan\|Tseng, Kai-Chi\|Yang, Tsai-Sheng\|Yeh, Chien-Yuh\|You, Jeng-Fu\|Hung, Hsin-Yuan\|Chen, Shu-Jen\|Chen, Hua-Chien
PMID:	25060070

122.
Journal:	Clin Res Hepatol Gastroenterol. 2015 Apr;39(2):267-73.
Title:	LGR5, a relevant marker of cancer stem cells, indicates a poor prognosis in colorectal cancer patients: a meta-analysis.
Author:	Han, Ye\|Xue, Xiaofeng\|Jiang, Min\|Guo, Xiaobo\|Li, Pu\|Liu, Fei\|Yuan, Bin\|Shen, Yichen\|Guo, Xingpo\|Zhi, Qiaoming\|Zhao, Hong
PMID:	25193236

123.
Journal:	Lab Invest. 2015 Jan;95(1):100-12.
Title:	Methods for detecting circulating cancer stem cells (CCSCs) as a novel approach for diagnosis of colon cancer relapse/metastasis.
Author:	Kantara, Carla\|O'Connell, Malaney Ravae\|Luthra, Gurinder\|Gajjar, Aakash\|Sarkar, Shubhashish\|Ullrich, Robert Leo\|Singh, Pomila
PMID:	25347154

124.
Journal:	Nat Med. 2015 Jan;21(1):62-70.
Title:	Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche.
Author:	Davis, Hayley\|Irshad, Shazia\|Bansal, Mukesh\|Rafferty, Hannah\|Boitsova, Tatjana\|Bardella, Chiara\|Jaeger, Emma\|Lewis, Annabelle\|Freeman-Mills, Luke\|Giner, Francesc Castro\|Rodenas-Cuadrado, Pedro\|Mallappa, Sreelakshmi\|Clark, Susan\|Thomas, Huw\|Jeffery, Rosema
PMID:	25419707

125.
Journal:	Mol Med Rep. 2015 Apr;11(4):2947-52.
Title:	MicroRNA-100 functions as a tumor suppressor by inhibiting Lgr5 expression in colon cancer cells.
Author:	Zhou, Ming-Kai\|Liu, Xiao-Jun\|Zhao, Zhi-Guo\|Cheng, Yi-Meng
PMID:	25483280

126.
Journal:	Oncotarget. 2015 Jan 1;6(1):409-26.
Title:	Irinotecan treatment and senescence failure promote the emergence of more transformed and invasive cells that depend on anti-apoptotic Mcl-1.
Author:	Jonchere, Barbara\|Vetillard, Alexandra\|Toutain, Bertrand\|Lam, David\|Bernard, Anne Charlotte\|Henry, Cecile\|De Carne Trecesson, Sophie\|Gamelin, Erick\|Juin, Philippe\|Guette, Catherine\|Coqueret, Olivier
PMID:	25565667

127.
Journal:	Br J Cancer. 2015 Feb 17;112(4):714-9.
Title:	Nutrient stress alters the glycosylation status of LGR5 resulting in reduced protein stability and membrane localisation in colorectal tumour cells: implications for targeting cancer stem cells.
Author:	Morgan, R G\|Molnar, E\|Jones, R F\|Collard, T J\|Lane, J D\|Greenhough, A\|Paraskeva, C\|Williams, A C
PMID:	25611300

128.
Journal:	Int J Oncol. 2015 Apr;46(4):1551-9.
Title:	The effectiveness of an anti-human IL-6 receptor monoclonal antibody combined with chemotherapy to target colon cancer stem-like cells.
Author:	Ying, Jin\|Tsujii, Masahiko\|Kondo, Jumpei\|Hayashi, Yoshito\|Kato, Motohiko\|Akasaka, Tomofumi\|Inoue, Takuta\|Shiraishi, Eri\|Inoue, Tahahiro\|Hiyama, Satoshi\|Tsujii, Yoshiki\|Maekawa, Akira\|Kawai, Shoichiro\|Fujinaga, Tetsuji\|Araki, Maekawa\|Shinzaki, Shinichiro\|W
PMID:	25625841

129.
Journal:	Tumour Biol. 2015 Jun;36(6):4801-10.
Title:	Upregulation of circulating cancer stem cell marker, DCLK1 but not Lgr5, in chemoradiotherapy-treated colorectal cancer patients.
Author:	Mirzaei, Alireza\|Tavoosidana, Gholamreza\|Modarressi, Mohammad Hossein\|Rad, Afshin Abdi\|Fazeli, Mohammad Sadegh\|Shirkoohi, Reza\|Tavakoli-Yaraki, Masoumeh\|Madjd, Zahra
PMID:	25631749

130.
Journal:	Clin Colorectal Cancer. 2015 Jun;14(2):63-71.
Title:	Clinical implications of intestinal stem cell markers in colorectal cancer.
Author:	Espersen, Maiken Lise Marcker\|Olsen, Jesper\|Linnemann, Dorte\|Hogdall, Estrid\|Troelsen, Jesper T
PMID:	25657049

131.
Journal:	Pharmacogenomics J. 2015 Oct;15(5):391-6.
Title:	LGR5 rs17109924 is a predictive genetic biomarker for time to recurrence in patients with colon cancer treated with 5-fluorouracil-based adjuvant chemotherapy.
Author:	Szkandera, J\|Herzog, S\|Pichler, M\|Stiegelbauer, V\|Stotz, M\|Schaberl-Moser, R\|Samonigg, H\|Asslaber, M\|Lax, S\|Leitner, G\|Renner, W\|Lenz, H-J\|Berghold, A\|Gerger, A
PMID:	25665511

132.
Journal:	World J Gastroenterol. 2015 Feb 21;21(7):2005-10.
Title:	Injury-associated reacquiring of intestinal stem cell function.
Author:	Sipos, Ferenc\|Muzes, Gyorgyi
PMID:	25717233

133.
Journal:	Carcinogenesis. 2015 Jun;36(6):622-31.
Title:	Bcl11b SWI/SNF-complex subunit modulates intestinal adenoma and regeneration after gamma-irradiation through Wnt/beta-catenin pathway.
Author:	Sakamaki, Akira\|Katsuragi, Yoshinori\|Otsuka, Kensuke\|Tomita, Masanori\|Obata, Miki\|Iwasaki, Tomohiro\|Abe, Manabu\|Sato, Toshihiro\|Ochiai, Masako\|Sakuraba, Yoshiyuki\|Aoyagi, Yutaka\|Gondo, Yoichi\|Sakimura, Kenji\|Nakagama, Hitoshi\|Mishima, Yukio\|Kominami, Ryo
PMID:	25827435

134.
Journal:	J Radiat Res. 2015 Jul;56(4):615-22.
Title:	Effects of dose rates on radiation-induced replenishment of intestinal stem cells determined by Lgr5 lineage tracing.
Author:	Otsuka, Kensuke\|Iwasaki, Toshiyasu
PMID:	25832104

135.
Journal:	Sci Transl Med. 2015 Apr 1;7(281):281ra44.
Title:	An EphB-Abl signaling pathway is associated with intestinal tumor initiation and growth.
Author:	Kundu, Parag\|Genander, Maria\|Straat, Klas\|Classon, Johanna\|Ridgway, Rachel A\|Tan, Ee Hong\|Bjork, Jan\|Martling, Anna\|van Es, Johan\|Sansom, Owen J\|Clevers, Hans\|Pettersson, Sven\|Frisen, Jonas
PMID:	25834110

136.
Journal:	Tumour Biol. 2015 Sep;36(9):6759-64.
Title:	Role of Lgr5-positive cells in colorectal cancer.
Author:	Ding, Honghua\|Wang, Chungang
PMID:	25835970

137.
Journal:	Oncotarget. 2015 May 20;6(14):12763-73.
Title:	The prognostic value of the stem-like group in colorectal cancer using a panel of immunohistochemistry markers.
Author:	Ong, Chee Wee\|Chong, Pei Yi\|McArt, Darragh G\|Chan, Jason Yongsheng\|Tan, Hwee Tong\|Kumar, Alan Prem\|Chung, Maxey C M\|Clement, Marie-Veronique\|Soong, Richie\|Van Schaeybroeck, Sandra\|Waugh, David J J\|Johnston, Patrick G\|Dunne, Philip D\|Salto-Tellez, Manuel
PMID:	25906747

138.
Journal:	Cell. 2015 May 7;161(4):933-45.
Title:	Prospective derivation of a living organoid biobank of colorectal cancer patients.
Author:	van de Wetering, Marc\|Francies, Hayley E\|Francis, Joshua M\|Bounova, Gergana\|Iorio, Francesco\|Pronk, Apollo\|van Houdt, Winan\|van Gorp, Joost\|Taylor-Weiner, Amaro\|Kester, Lennart\|McLaren-Douglas, Anne\|Blokker, Joyce\|Jaksani, Sridevi\|Bartfeld, Sina\|Volckman,
PMID:	25957691

139.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2015 Jul 1;309(1):G1-9.
Title:	A bioassay to measure energy metabolism in mouse colonic crypts, organoids, and sorted stem cells.
Author:	Fan, Yang-Yi\|Davidson, Laurie A\|Callaway, Evelyn S\|Wright, Gus A\|Safe, Stephen\|Chapkin, Robert S
PMID:	25977509

140.
Journal:	Dev Biol. 2015 Aug 15;404(2):35-48.
Title:	A conditional transgenic mouse line for targeted expression of the stem cell marker LGR5.
Author:	Norum, Jens Henrik\|Bergstrom, Asa\|Andersson, Agneta Birgitta\|Kuiper, Raoul V\|Hoelzl, Maria A\|Sorlie, Therese\|Toftgard, Rune
PMID:	26003047

141.
Journal:	Cancer Sci. 2015 Aug;106(8):1000-7.
Title:	Atonal homolog 1 protein stabilized by tumor necrosis factor alpha induces high malignant potential in colon cancer cell line.
Author:	Fukushima, Keita\|Tsuchiya, Kiichiro\|Kano, Yoshihito\|Horita, Nobukatsu\|Hibiya, Shuji\|Hayashi, Ryohei\|Kitagaki, Keisuke\|Negi, Mariko\|Itoh, Eisaku\|Akashi, Takumi\|Eishi, Yoshinobu\|Oshima, Shigeru\|Nagaishi, Takashi\|Okamoto, Ryuichi\|Nakamura, Tetsuya\|Watanabe,
PMID:	26017781

142.
Journal:	Gastroenterology. 2015 Sep;149(3):705-17.e2.
Title:	KIT Signaling Promotes Growth of Colon Xenograft Tumors in Mice and Is Up-Regulated in a Subset of Human Colon Cancers.
Author:	Chen, Evan C\|Karl, Taylor A\|Kalisky, Tomer\|Gupta, Santosh K\|O'Brien, Catherine A\|Longacre, Teri A\|van de Rijn, Matt\|Quake, Stephen R\|Clarke, Michael F\|Rothenberg, Michael E
PMID:	26026391

143.
Journal:	Cell Stem Cell. 2015 Jun 4;16(6):627-38.
Title:	Krt19(+)/Lgr5(-) Cells Are Radioresistant Cancer-Initiating Stem Cells in the Colon and Intestine.
Author:	Asfaha, Samuel\|Hayakawa, Yoku\|Muley, Ashlesha\|Stokes, Sarah\|Graham, Trevor A\|Ericksen, Russell E\|Westphalen, Christoph B\|von Burstin, Johannes\|Mastracci, Teresa L\|Worthley, Daniel L\|Guha, Chandhan\|Quante, Michael\|Rustgi, Anil K\|Wang, Timothy C
PMID:	26046762

144.
Journal:	Gastroenterology. 2015 Oct;149(4):1006-16.e9.
Title:	FOXM1-Induced PRX3 Regulates Stemness and Survival of Colon Cancer Cells via Maintenance of Mitochondrial Function.
Author:	Song, In-Sung\|Jeong, Yu Jeong\|Jeong, Seung Hun\|Heo, Hye Jin\|Kim, Hyoung Kyu\|Bae, Ki Beom\|Park, Young-Ho\|Kim, Sun Uk\|Kim, Jin-Man\|Kim, Nari\|Ko, Kyung Soo\|Rhee, Byoung Doo\|Han, Jin
PMID:	26091938

145.
Journal:	Oncol Lett. 2015 Jun;9(6):2859-2863.
Title:	LGR5 promotes the proliferation of colorectal cancer cells via the Wnt/beta-catenin signaling pathway.
Author:	Lin, Y U\|Wu, Tingyu\|Yao, Qianqian\|Zi, Shuming\|Cui, Long\|Yang, Ming\|Li, Jinming
PMID:	26137160

146.
Journal:	Cancer Lett. 2015 Oct 10;367(1):34-42.
Title:	Colorectal cancer-derived tumor spheroids retain the characteristics of original tumors.
Author:	Lee, Sun-Hwa\|Hong, Jun Hwa\|Park, Hwan Ki\|Park, Jun Seok\|Kim, Bo-Kyung\|Lee, Jung-Yi\|Jeong, Ji Yun\|Yoon, Ghil Suk\|Inoue, Masahiro\|Choi, Gyu-Seog\|Lee, In-Kyu
PMID:	26185002

147.
Journal:	Anticancer Drugs. 2015 Oct;26(9):942-7.
Title:	SW480 colorectal cancer cells that naturally express Lgr5 are more sensitive to the most common chemotherapeutic agents than Lgr5-negative SW480 cells.
Author:	Planutis, Andrius K\|Holcombe, Randall F\|Planoutene, Marina V\|Planoutis, Kiastoutis S
PMID:	26196680

148.
Journal:	Toxicol Appl Pharmacol. 2015 Oct 15;288(2):258-68.
Title:	4-Acetylantroquinonol B inhibits colorectal cancer tumorigenesis and suppresses cancer stem-like phenotype.
Author:	Chang, Tung-Cheng\|Yeh, Chi-Tai\|Adebayo, Bamodu Oluwaseun\|Lin, Ying-Chin\|Deng, Li\|Rao, Yerra Koteswara\|Huang, Chun-Chih\|Lee, Wei-Hwa\|Wu, Alexander T H\|Hsiao, Michael\|Wu, Chih-Hsiung\|Wang, Liang-Shun\|Tzeng, Yew-Min
PMID:	26235807

149.
Journal:	Carcinogenesis. 2015 Oct;36(10):1235-44.
Title:	DNA repair by MGMT, but not AAG, causes a threshold in alkylation-induced colorectal carcinogenesis.
Author:	Fahrer, Jorg\|Frisch, Janina\|Nagel, Georg\|Kraus, Alexander\|Dorsam, Bastian\|Thomas, Adam D\|Reissig, Sonja\|Waisman, Ari\|Kaina, Bernd
PMID:	26243310

150.
Journal:	PLoS One. 2015 Aug 18;10(8):e0134212.
Title:	Ablation of Doublecortin-Like Kinase 1 in the Colonic Epithelium Exacerbates Dextran Sulfate Sodium-Induced Colitis.
Author:	Qu, Dongfeng\|Weygant, Nathaniel\|May, Randal\|Chandrakesan, Parthasarathy\|Madhoun, Mohammad\|Ali, Naushad\|Sureban, Sripathi M\|An, Guangyu\|Schlosser, Michael J\|Houchen, Courtney W
PMID:	26285154

151.
Journal:	Curr Pharmacol Rep. 2015 Aug 1;1(4):217-222.
Title:	Regulation of miRNAs by agents targeting the tumor stem cell markers DCLK1, MSI1, LGR5, and BMI1.
Author:	Sureban, Sripathi M\|Qu, Dongfeng\|Houchen, Courtney W
PMID:	26366338

152.
Journal:	PLoS One. 2015 Sep 14;10(9):e0138336.
Title:	ERBB3 Positively Correlates with Intestinal Stem Cell Markers but Marks a Distinct Non Proliferative Cell Population in Colorectal Cancer.
Author:	Jarde, Thierry\|Kass, Lisa\|Staples, Margaret\|Lescesen, Helen\|Carne, Peter\|Oliva, Karen\|McMurrick, Paul J\|Abud, Helen E
PMID:	26367378

153.
Journal:	Sci Rep. 2015 Sep 21;5:14291.
Title:	REG4 is a transcriptional target of GATA6 and is essential for colorectal tumorigenesis.
Author:	Kawasaki, Yoshihiro\|Matsumura, Kosuke\|Miyamoto, Masaya\|Tsuji, Shinnosuke\|Okuno, Masumi\|Suda, Sakiko\|Hiyoshi, Masaya\|Kitayama, Joji\|Akiyama, Tetsu
PMID:	26387746

154.
Journal:	Oncotarget. 2015 Oct 27;6(33):34389-401.
Title:	Clusterin, a gene enriched in intestinal stem cells, is required for L1-mediated colon cancer metastasis.
Author:	Shapiro, Beny\|Tocci, Piera\|Haase, Gal\|Gavert, Nancy\|Ben-Ze'ev, Avri
PMID:	26399194

155.
Journal:	Clin Exp Pharmacol Physiol. 2015 Dec;42(12):1317-26.
Title:	PI3K/Akt/mTOR pathway dual inhibitor BEZ235 suppresses the stemness of colon cancer stem cells.
Author:	Chen, Jiezhong\|Shao, Renfu\|Li, Feng\|Monteiro, Michael\|Liu, Jun-Ping\|Xu, Zhi Ping\|Gu, Wenyi
PMID:	26399781

156.
Journal:	Cancer Lett. 2015 Dec 28;369(2):336-43.
Title:	Obesity promotes colonic stem cell expansion during cancer initiation.
Author:	DeClercq, V\|McMurray, D N\|Chapkin, R S
PMID:	26455770

157.
Journal:	Nature. 2015 Oct 29;526(7575):715-8.
Title:	Yap-dependent reprogramming of Lgr5(+) stem cells drives intestinal regeneration and cancer.
Author:	Gregorieff, Alex\|Liu, Yu\|Inanlou, Mohammad R\|Khomchuk, Yuliya\|Wrana, Jeffrey L
PMID:	26503053

158.
Journal:	PLoS Genet. 2015 Nov 3;11(11):e1005638.
Title:	Tissue-Specific Effects of Reduced beta-catenin Expression on Adenomatous Polyposis Coli Mutation-Instigated Tumorigenesis in Mouse Colon and Ovarian Epithelium.
Author:	Feng, Ying\|Sakamoto, Naoya\|Wu, Rong\|Liu, Jie-Yu\|Wiese, Alexandra\|Green, Maranne E\|Green, Megan\|Akyol, Aytekin\|Roy, Badal C\|Zhai, Yali\|Cho, Kathleen R\|Fearon, Eric R
PMID:	26528816

159.
Journal:	Sci Transl Med. 2015 Nov 18;7(314):314ra186.
Title:	Targeting LGR5+ cells with an antibody-drug conjugate for the treatment of colon cancer.
Author:	Junttila, Melissa R\|Mao, Weiguang\|Wang, Xi\|Wang, Bu-Er\|Pham, Thinh\|Flygare, John\|Yu, Shang-Fan\|Yee, Sharon\|Goldenberg, David\|Fields, Carter\|Eastham-Anderson, Jeffrey\|Singh, Mallika\|Vij, Rajesh\|Hongo, Jo-Anne\|Firestein, Ron\|Schutten, Melissa\|Flagella, Kell
PMID:	26582901

160.
Journal:	PLoS One. 2015 Nov 24;10(11):e0143513.
Title:	Lgr5 Methylation in Cancer Stem Cell Differentiation and Prognosis-Prediction in Colorectal Cancer.
Author:	Su, Shasha\|Hong, Feng\|Liang, Yanling\|Zhou, Jieqiong\|Liang, Yan\|Chen, Kequan\|Wang, Xinying\|Wang, Zhongqiu\|Wang, Zhiqing\|Chang, Cassie\|Han, Weihua\|Gong, Wei\|Qin, Haitao\|Jiang, Bo\|Xiong, Huabao\|Peng, Liang
PMID:	26599100

161.
Journal:	Cancer Res. 2015 Dec 15;75(24):5392-7.
Title:	Targeted Deletion of p53 in Lgr5-Expressing Intestinal Stem Cells Promotes Colon Tumorigenesis in a Preclinical Model of Colitis-Associated Cancer.
Author:	Davidson, Laurie A\|Callaway, Evelyn S\|Kim, Eunjoo\|Weeks, Brad R\|Fan, Yang-Yi\|Allred, Clinton D\|Chapkin, Robert S
PMID:	26631266

162.
Journal:	Acta Histochem Cytochem. 2015 Oct 29;48(5):159-64.
Title:	Intensive Immunofluorescence Staining Methods for Low Expression Protein: Detection of Intestinal Stem Cell Marker LGR5.
Author:	Yamazaki, Masaki\|Kato, Atsuhiko\|Zaitsu, Yoko\|Watanabe, Takeshi\|Iimori, Makoto\|Funahashi, Shinichi\|Kitao, Hiroyuki\|Saeki, Hiroshi\|Oki, Eiji\|Suzuki, Masami
PMID:	26633908

163.
Journal:	BMC Cancer. 2015 Dec 16;15:948.
Title:	Lgr5 expression is a valuable prognostic factor for colorectal cancer: evidence from a meta-analysis.
Author:	Jiang, Yangyan\|Li, Wenlu\|He, Xin\|Zhang, Hongbo\|Jiang, Fangzhen\|Chen, Zhigang
PMID:	26674601

164.
Journal:	Cell Biochem Biophys. 2015 Nov;73(2):393-397.
Title:	A Study on the Mechanism of Low-Expressed Cancer Stem Cell Marker Lgr5 in Inhibition of the Proliferation and Invasion of Colorectal Carcinoma.
Author:	Jia, Houjun\|Xiang, Lin\|Wang, Ziwei\|Zhou, Qipeng
PMID:	27352328

165.
Journal:	J Steroid Biochem Mol Biol. 2016 Jan;155(Pt B):224-30.
Title:	Effect of 1,25-dihydroxyvitamin D3 on the Wnt pathway in non-malignant colonic cells.
Author:	Groschel, Charlotte\|Aggarwal, Abhishek\|Tennakoon, Samawansha\|Hobaus, Julia\|Prinz-Wohlgenannt, Maximilian\|Marian, Brigitte\|Heffeter, Petra\|Berger, Walter\|Kallay, Eniko
PMID:	25777538

166.
Journal:	Oncogene. 2016 Feb 4;35(5):549-57.
Title:	Induction of the intestinal stem cell signature gene SMOC-2 is required for L1-mediated colon cancer progression.
Author:	Shvab, A\|Haase, G\|Ben-Shmuel, A\|Gavert, N\|Brabletz, T\|Dedhar, S\|Ben-Ze'ev, A
PMID:	25915847

167.
Journal:	Histopathology. 2016 Mar;68(4):567-77.
Title:	Distribution of intestinal stem cell markers in colorectal precancerous lesions.
Author:	Jang, Bo Gun\|Kim, Hye Sung\|Kim, Kyung Ju\|Rhee, Ye-Young\|Kim, Woo Ho\|Kang, Gyeong Hoon
PMID:	26212207

168.
Journal:	Clin Cancer Res. 2016 Jan 1;22(1):230-242.
Title:	EphA2 Expression Is a Key Driver of Migration and Invasion and a Poor Prognostic Marker in Colorectal Cancer.
Author:	Dunne, Philip D\|Dasgupta, Sonali\|Blayney, Jaine K\|McArt, Darragh G\|Redmond, Keara L\|Weir, Jessica-Anne\|Bradley, Conor A\|Sasazuki, Takehiko\|Shirasawa, Senji\|Wang, Tingting\|Srivastava, Supriya\|Ong, Chee Wee\|Arthur, Ken\|Salto-Tellez, Manuel\|Wilson, Richard H
PMID:	26283684

169.
Journal:	Mol Carcinog. 2016 Nov;55(11):1503-1516.
Title:	RNA binding protein RBM3 increases beta-catenin signaling to increase stem cell characteristics in colorectal cancer cells.
Author:	Venugopal, Anand\|Subramaniam, Dharmalingam\|Balmaceda, Julia\|Roy, Badal\|Dixon, Dan A\|Umar, Shahid\|Weir, Scott J\|Anant, Shrikant
PMID:	26331352

170.
Journal:	Tumour Biol. 2016 Feb;37(2):2405-14.
Title:	A new insight into cancer stem cell markers: Could local and circulating cancer stem cell markers correlate in colorectal cancer?
Author:	Mirzaei, Alireza\|Tavoosidana, Gholamreza\|Rad, Afshin Abdi\|Rezaei, Farhad\|Tavakoli-Yaraki, Masoumeh\|Kadijani, Azade Amini\|Khalili, Ehsan\|Madjd, Zahra
PMID:	26383518

171.
Journal:	Gastric Cancer. 2016 Jul;19(3):767-77.
Title:	Prognostic significance of leucine-rich-repeat-containing G-protein-coupled receptor 5, an intestinal stem cell marker, in gastric carcinomas.
Author:	Jang, Bo Gun\|Lee, Byung Lan\|Kim, Woo Ho
PMID:	26386561

172.
Journal:	Tumour Biol. 2016 Jan;37(1):7-21.
Title:	Cancer stem cells in human digestive tract malignancies.
Author:	Rassouli, Fatemeh B\|Matin, Maryam M\|Saeinasab, Morvarid
PMID:	26446457

173.
Journal:	Int J Cancer. 2016 Apr 15;138(8):1971-81.
Title:	CD90(+) stromal cells are the major source of IL-6, which supports cancer stem-like cells and inflammation in colorectal cancer.
Author:	Huynh, Phuong T\|Beswick, Ellen J\|Coronado, Yun A\|Johnson, Paul\|O'Connell, Malaney R\|Watts, Tammara\|Singh, Pomila\|Qiu, Suimin\|Morris, Katherine\|Powell, Don W\|Pinchuk, Irina V
PMID:	26595254

174.
Journal:	Carcinogenesis. 2016 Feb;37(2):206-14.
Title:	Homeostatic responses of colonic LGR5+ stem cells following acute in vivo exposure to a genotoxic carcinogen.
Author:	Kim, Eunjoo\|Davidson, Laurie A\|Zoh, Roger S\|Hensel, Martha E\|Patil, Bhimanagouda S\|Jayaprakasha, Guddadarangavvanahally K\|Callaway, Evelyn S\|Allred, Clinton D\|Turner, Nancy D\|Weeks, Brad R\|Chapkin, Robert S
PMID:	26717997

175.
Journal:	PLoS One. 2016 Jan 8;11(1):e0146052.
Title:	What Do We Learn from Spheroid Culture Systems? Insights from Tumorspheres Derived from Primary Colon Cancer Tissue.
Author:	Qureshi-Baig, Komal\|Ullmann, Pit\|Rodriguez, Fabien\|Frasquilho, Sonia\|Nazarov, Petr V\|Haan, Serge\|Letellier, Elisabeth
PMID:	26745821

176.
Journal:	BMC Cancer. 2016 Jan 12;16:12.
Title:	Lgr5 expression is a valuable prognostic factor for colorectal cancer: evidence from a meta-analysis.
Author:	Jiang, Yangyan\|Li, Wenlu\|He, Xin\|Zhang, Hongbo\|Jiang, Fangzhen\|Chen, Zhigang
PMID:	26758198

177.
Journal:	Cell Stem Cell. 2016 Feb 4;18(2):189-202.
Title:	A miR-34a-Numb Feedforward Loop Triggered by Inflammation Regulates Asymmetric Stem Cell Division in Intestine and Colon Cancer.
Author:	Bu, Pengcheng\|Wang, Lihua\|Chen, Kai-Yuan\|Srinivasan, Tara\|Murthy, Preetish Kadur Lakshminarasimha\|Tung, Kuei-Ling\|Varanko, Anastasia Kristine\|Chen, Huanhuan Joyce\|Ai, Yiwei\|King, Sarah\|Lipkin, Steven M\|Shen, Xiling
PMID:	26849305

178.
Journal:	Anal Chem. 2016 Apr 5;88(7):3953-8.
Title:	Rapid Recognition and Isolation of Live Colon Cancer Stem Cells by Using Metabolic Labeling of Azido Sugar and Magnetic Beads.
Author:	Sun, Lingbo\|Fu, Hongxia\|Li, Yanru\|Duan, Xinrui\|Li, Zhengping
PMID:	26937691

179.
Journal:	Br J Cancer. 2016 May 24;114(11):1251-60.
Title:	Full-length LGR5-positive cells have chemoresistant characteristics in colorectal cancer.
Author:	Osawa, Hideki\|Takahashi, Hidekazu\|Nishimura, Junichi\|Ohta, Katsuya\|Haraguchi, Naotsugu\|Hata, Taishi\|Yamamoto, Hirofumi\|Mizushima, Tsunekazu\|Takemasa, Ichiro\|Doki, Yuichiro\|Mori, Masaki
PMID:	27140312

180.
Journal:	Sci Rep. 2016 May 4;6:25311.
Title:	Inhibition of DNA Methylation Suppresses Intestinal Tumor Organoids by Inducing an Anti-Viral Response.
Author:	Saito, Yoshimasa\|Nakaoka, Toshiaki\|Sakai, Kasumi\|Muramatsu, Toshihide\|Toshimitsu, Kohta\|Kimura, Masaki\|Kanai, Takanori\|Sato, Toshiro\|Saito, Hidetsugu
PMID:	27143627

181.
Journal:	Am J Transl Res. 2016 Feb 15;8(2):354-64. eCollection 2016.
Title:	RSPO2 enriches LGR5(+) spheroid colon cancer stem cells and promotes its metastasis by epithelial-mesenchymal transition.
Author:	Zhang, Shi\|Han, Xiaoyan\|Wei, Bo\|Fang, Jiafeng\|Wei, Hongbo
PMID:	27158331

182.
Journal:	Mol Cancer Ther. 2016 Jul;15(7):1580-90.
Title:	LGR5-Targeted Antibody-Drug Conjugate Eradicates Gastrointestinal Tumors and Prevents Recurrence.
Author:	Gong, Xing\|Azhdarinia, Ali\|Ghosh, Sukhen C\|Xiong, Wei\|An, Zhiqiang\|Liu, Qingyun\|Carmon, Kendra S
PMID:	27207778

183.
Journal:	Cancer Prev Res (Phila). 2016 Sep;9(9):721-31.
Title:	Celecoxib Alters the Intestinal Microbiota and Metabolome in Association with Reducing Polyp Burden.
Author:	Montrose, David C\|Zhou, Xi Kathy\|McNally, Erin M\|Sue, Erika\|Yantiss, Rhonda K\|Gross, Steven S\|Leve, Nitai D\|Karoly, Edward D\|Suen, Chen S\|Ling, Lilan\|Benezra, Robert\|Pamer, Eric G\|Dannenberg, Andrew J
PMID:	27432344

184.
Journal:	Acta Oncol. 2016 Dec;55(12):1425-1433.
Title:	LGR5 and CD133 as prognostic and predictive markers for fluoropyrimidine-based adjuvant chemotherapy in colorectal cancer.
Author:	Stanisavljevic, Luka\|Myklebust, Mette P\|Leh, Sabine\|Dahl, Olav
PMID:	27435662

185.
Journal:	Cell Rep. 2016 Sep 20;16(12):3297-3310.
Title:	Control of Paneth Cell Fate, Intestinal Inflammation, and Tumorigenesis by PKClambda/iota.
Author:	Nakanishi, Yuki\|Reina-Campos, Miguel\|Nakanishi, Naoko\|Llado, Victoria\|Elmen, Lisa\|Peterson, Scott\|Campos, Alex\|De, Surya K\|Leitges, Michael\|Ikeuchi, Hiroki\|Pellecchia, Maurizio\|Blumberg, Richard S\|Diaz-Meco, Maria T\|Moscat, Jorge
PMID:	27653691

186.
Journal:	Cell Death Dis. 2016 Nov 10;7(11):e2460.
Title:	Rapidly cycling Lgr5(+) stem cells are exquisitely sensitive to extrinsic dietary factors that modulate colon cancer risk.
Author:	Kim, Eunjoo\|Davidson, Laurie A\|Zoh, Roger S\|Hensel, Martha E\|Salinas, Michael L\|Patil, Bhimanagouda S\|Jayaprakasha, Guddadarangavvanahally K\|Callaway, Evelyn S\|Allred, Clinton D\|Turner, Nancy D\|Weeks, Brad R\|Chapkin, Robert S
PMID:	27831561

187.
Journal:	Oncotarget. 2016 Dec 6;7(49):81144-81155.
Title:	Co-expression of Lgr5 and CXCR4 characterizes cancer stem-like cells of colorectal cancer.
Author:	Wu, Weidong\|Cao, Jun\|Ji, Zhengyi\|Wang, Jingjue\|Jiang, Tao\|Ding, Honghua
PMID:	27835894

188.
Journal:	BMC Cancer. 2016 Nov 17;16(1):896.
Title:	Salinomycin inhibits metastatic colorectal cancer growth and interferes with Wnt/beta-catenin signaling in CD133(+) human colorectal cancer cells.
Author:	Klose, Johannes\|Eissele, Jana\|Volz, Claudia\|Schmitt, Steffen\|Ritter, Alina\|Ying, Shen\|Schmidt, Thomas\|Heger, Ulrike\|Schneider, Martin\|Ulrich, Alexis
PMID:	27855654

189.
Journal:	Oncotarget. 2016 Dec 27;7(52):86695-86703.
Title:	Loss of ZG16 is regulated by miR-196a and contributes to stemness and progression of colorectal cancer.
Author:	Chen, Xiaobing\|Du, Peng\|She, Junjun\|Cao, Liang\|Li, Yingchao\|Xia, Hongping
PMID:	27880730

190.
Journal:	Stem Cells Int. 2016;2016:7053872.
Title:	Establishment of a Novel Model for Anticancer Drug Resistance in Three-Dimensional Primary Culture of Tumor Microenvironment.
Author:	Usui, Tatsuya\|Sakurai, Masashi\|Enjoji, Shuhei\|Kawasaki, Hideyoshi\|Umata, Koji\|Ohama, Takashi\|Fujiwara, Nobuyuki\|Yabe, Ryotaro\|Tsuji, Shunya\|Yamawaki, Hideyuki\|Hazama, Shoichi\|Takenouchi, Hiroko\|Nakajima, Masao\|Tsunedomi, Ryouichi\|Suzuki, Nobuaki\|Nagano, H
PMID:	28119740

191.
Journal:	Ann Transl Med. 2016 Dec;4(24):508.
Title:	Targeting colorectal cancer (stem-like) cells using LGR5 directed antibody drug conjugates.
Author:	Hirsch, Daniela\|Ried, Thomas
PMID:	28149870

192.
Journal:	Mol Carcinog. 2017 Nov;56(11):2372-2381.
Title:	Differential expression of LEF1/TCFs family members in colonic carcinogenesis.
Author:	Han, Wenxiao\|He, Longmei\|Cao, Bangrong\|Zhao, Xinhua\|Zhang, Kaitai\|Li, Yan\|Beck, Paul\|Zhou, Zhixiang\|Tian, Yantao\|Cheng, Shujun\|Wang, Hongying
PMID:	27433921

193.
Journal:	Gut. 2017 Jun;66(6):1095-1105.
Title:	RSPO3 expands intestinal stem cell and niche compartments and drives tumorigenesis.
Author:	Hilkens, John\|Timmer, Nikki C\|Boer, Mandy\|Ikink, Gerjon J\|Schewe, Matthias\|Sacchetti, Andrea\|Koppens, Martijn A J\|Song, Ji-Ying\|Bakker, Elvira R M
PMID:	27511199

194.
Journal:	Curr Stem Cell Res Ther. 2017;12(1):19-30.
Title:	Role of Stem Cells in Colorectal Cancer Progression and Prognostic and Predictive Characteristics of Stem Cell Markers in Colorectal Cancer.
Author:	Fedyanin, Mikhail\|Anna, Popova\|Elizaveta, Polyanskaya\|Sergei, Tjulandin
PMID:	27593447

195.
Journal:	Toxicol Sci. 2017 Jan;155(1):224-233.
Title:	From the Cover: PhIP/DSS-Induced Colon Carcinogenesis in CYP1A-Humanized Mice and the Possible Role of Lgr5+ Stem Cells.
Author:	Chen, Jayson X\|Wang, Hong\|Liu, Anna\|Zhang, Lanjing\|Reuhl, Kenneth\|Yang, Chung S
PMID:	27664423

196.
Journal:	Oncol Res. 2017 May 24;25(5):709-719.
Title:	Overexpression of PER3 Inhibits Self-Renewal Capability and Chemoresistance of Colorectal Cancer Stem-Like Cells via Inhibition of Notch and beta-Catenin Signaling.
Author:	Zhang, Feng\|Sun, Hong\|Zhang, Sai\|Yang, Xin\|Zhang, Guogang\|Su, Tao
PMID:	27983919

197.
Journal:	J Exp Clin Cancer Res. 2017 Jan 23;36(1):16.
Title:	MIF/CD74 axis is a target for novel therapies in colon carcinomatosis.
Author:	Bozzi, Fabio\|Mogavero, Angela\|Varinelli, Luca\|Belfiore, Antonino\|Manenti, Giacomo\|Caccia, Claudio\|Volpi, Chiara C\|Beznoussenko, Galina V\|Milione, Massimo\|Leoni, Valerio\|Gloghini, Annunziata\|Mironov, Alexandre A\|Leo, Ermanno\|Pilotti, Silvana\|Pierotti, Marc
PMID:	28114961

198.
Journal:	Mol Cancer. 2017 Feb 1;16(1):30.
Title:	Dclk1, a tumor stem cell marker, regulates pro-survival signaling and self-renewal of intestinal tumor cells.
Author:	Chandrakesan, Parthasarathy\|Yao, Jiannan\|Qu, Dongfeng\|May, Randal\|Weygant, Nathaniel\|Ge, Yang\|Ali, Naushad\|Sureban, Sripathi M\|Gude, Modhi\|Vega, Kenneth\|Bannerman-Menson, Eddie\|Xia, Lijun\|Bronze, Michael\|An, Guangyu\|Houchen, Courtney W
PMID:	28148261

199.
Journal:	Sci Rep. 2017 Feb 8;7:41838.
Title:	Intestinal cancer stem cells marked by Bmi1 or Lgr5 expression contribute to tumor propagation via clonal expansion.
Author:	Yanai, Hirotsugu\|Atsumi, Naho\|Tanaka, Toshihiro\|Nakamura, Naohiro\|Komai, Yoshihiro\|Omachi, Taichi\|Tanaka, Kiyomichi\|Ishigaki, Kazuhiko\|Saiga, Kazuho\|Ohsugi, Haruyuki\|Tokuyama, Yoko\|Imahashi, Yuki\|Ohe, Shuichi\|Hisha, Hiroko\|Yoshida, Naoko\|Kumano, Keiki\|Kon
PMID:	28176811

200.
Journal:	Endocr Relat Cancer. 2017 Jun;24(6):253-265.
Title:	Apc inactivation, but not obesity, synergizes with Pten deficiency to drive intestinal stem cell-derived tumorigenesis.
Author:	Tabrizian, Tahmineh\|Wang, Donghai\|Guan, Fangxia\|Hu, Zunju\|Beck, Amanda P\|Delahaye, Fabien\|Huffman, Derek M
PMID:	28351943

201.
Journal:	Nature. 2017 May 11;545(7653):187-192.
Title:	Visualization and targeting of LGR5(+) human colon cancer stem cells.
Author:	Shimokawa, Mariko\|Ohta, Yuki\|Nishikori, Shingo\|Matano, Mami\|Takano, Ai\|Fujii, Masayuki\|Date, Shoichi\|Sugimoto, Shinya\|Kanai, Takanori\|Sato, Toshiro
PMID:	28355176

202.
Journal:	Nature. 2017 Mar 29;543(7647):676-680.
Title:	A distinct role for Lgr5(+) stem cells in primary and metastatic colon cancer.
Author:	de Sousa e Melo, Felipe\|Kurtova, Antonina V\|Harnoss, Jonathan M\|Kljavin, Noelyn\|Hoeck, Joerg D\|Hung, Jeffrey\|Anderson, Jeffrey Eastham\|Storm, Elaine E\|Modrusan, Zora\|Koeppen, Hartmut\|Dijkgraaf, Gerrit J P\|Piskol, Robert\|de Sauvage, Frederic J
PMID:	28358093

203.
Journal:	Oncogenesis. 2017 Apr 3;6(4):e308.
Title:	Methylation of WNT target genes AXIN2 and DKK1 as robust biomarkers for recurrence prediction in stage II colon cancer.
Author:	Kandimalla, R\|Linnekamp, J F\|van Hooff, S\|Castells, A\|Llor, X\|Andreu, M\|Jover, R\|Goel, A\|Medema, J P
PMID:	28368388

204.
Journal:	Gastroenterology. 2017 Jul;153(1):205-218.e8.
Title:	SPDEF Induces Quiescence of Colorectal Cancer Cells by Changing the Transcriptional Targets of beta-catenin.
Author:	Lo, Yuan-Hung\|Noah, Taeko K\|Chen, Min-Shan\|Zou, Winnie\|Borras, Ester\|Vilar, Eduardo\|Shroyer, Noah F
PMID:	28390865

205.
Journal:	Nutrients. 2017 Apr 10;9(4). pii: nu9040368.
Title:	Targeting Colorectal Cancer Proliferation, Stemness and Metastatic Potential Using Brassicaceae Extracts Enriched in Isothiocyanates: A 3D Cell Model-Based Study.
Author:	Pereira, Lucilia P\|Silva, Patricia\|Duarte, Marlene\|Rodrigues, Liliana\|Duarte, Catarina M M\|Albuquerque, Cristina\|Serra, Ana Teresa
PMID:	28394276

206.
Journal:	Nat Biotechnol. 2017 Jun;35(6):569-576.
Title:	In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis.
Author:	Roper, Jatin\|Tammela, Tuomas\|Cetinbas, Naniye Malli\|Akkad, Adam\|Roghanian, Ali\|Rickelt, Steffen\|Almeqdadi, Mohammad\|Wu, Katherine\|Oberli, Matthias A\|Sanchez-Rivera, Francisco J\|Park, Yoona K\|Liang, Xu\|Eng, George\|Taylor, Martin S\|Azimi, Roxana\|Kedrin, Dmi
PMID:	28459449

207.
Journal:	Cancer Med. 2017 Jun;6(6):1378-1388.
Title:	Elevated expression of Tie1 is accompanied by acquisition of cancer stemness properties in colorectal cancer.
Author:	Torigata, Miku\|Yamakawa, Daishi\|Takakura, Nobuyuki
PMID:	28464467

208.
Journal:	Cell Rep. 2017 May 2;19(5):981-994.
Title:	The Induction of Selected Wnt Target Genes by Tcf1 Mediates Generation of Tumorigenic Colon Stem Cells.
Author:	Shiokawa, Daisuke\|Sato, Ai\|Ohata, Hirokazu\|Mutoh, Michihiro\|Sekine, Shigeki\|Kato, Mamoru\|Shibata, Tatsuhiro\|Nakagama, Hitoshi\|Okamoto, Koji
PMID:	28467911

209.
Journal:	EMBO Mol Med. 2017 Jul;9(7):869-879.
Title:	A genome editing approach to study cancer stem cells in human tumors.
Author:	Cortina, Carme\|Turon, Gemma\|Stork, Diana\|Hernando-Momblona, Xavier\|Sevillano, Marta\|Aguilera, Monica\|Tosi, Sebastien\|Merlos-Suarez, Anna\|Stephan-Otto Attolini, Camille\|Sancho, Elena\|Batlle, Eduard
PMID:	28468934

210.
Journal:	Oncotarget. 2017 Jul 11;8(28):45311-45322.
Title:	Temporal and spatial changes of cells positive for stem-like markers in different compartments and stages of human colorectal adenoma-carcinoma sequence.
Author:	Cui, Guanglin\|Xu, Gang\|Zhu, Li\|Pang, Zhigang\|Zheng, Wei\|Li, Zhenfeng\|Yuan, Aping
PMID:	28484082

211.
Journal:	Cancer Res. 2017 Jul 15;77(14):3778-3790.
Title:	An miRNA Expression Signature for the Human Colonic Stem Cell Niche Distinguishes Malignant from Normal Epithelia.
Author:	Viswanathan, Vignesh\|Damle, Shirish\|Zhang, Tao\|Opdenaker, Lynn\|Modarai, Shirin\|Accerbi, Monica\|Schmidt, Skye\|Green, Pamela\|Galileo, Deni\|Palazzo, Juan\|Fields, Jeremy\|Haghighat, Sepehr\|Rigoutsos, Isidore\|Gonye, Greg\|Boman, Bruce M
PMID:	28487386

212.
Journal:	EBioMedicine. 2017 Jul;21:104-116.
Title:	Histone Chaperone ASF1A Predicts Poor Outcomes for Patients With Gastrointestinal Cancer and Drives Cancer Progression by Stimulating Transcription of beta-Catenin Target Genes.
Author:	Liang, Xiuming\|Yuan, Xiaotian\|Yu, Jingya\|Wu, Yujiao\|Li, Kailin\|Sun, Chao\|Li, Shuyan\|Shen, Li\|Kong, Feng\|Jia, Jihui\|Bjorkholm, Magnus\|Xu, Dawei
PMID:	28625518

213.
Journal:	Stem Cell Reports. 2017 Aug 8;9(2):438-450.
Title:	RBP4-STRA6 Pathway Drives Cancer Stem Cell Maintenance and Mediates High-Fat Diet-Induced Colon Carcinogenesis.
Author:	Karunanithi, Sheelarani\|Levi, Liraz\|DeVecchio, Jennifer\|Karagkounis, George\|Reizes, Ofer\|Lathia, Justin D\|Kalady, Matthew F\|Noy, Noa
PMID:	28689994

214.
Journal:	Stem Cells. 2017 Sep;35(9):2027-2036.
Title:	Colorectal Cancer Stem Cells Acquire Chemoresistance Through the Upregulation of F-Box/WD Repeat-Containing Protein 7 and the Consequent Degradation of c-Myc.
Author:	Izumi, Daisuke\|Ishimoto, Takatsugu\|Miyake, Keisuke\|Eto, Tsugio\|Arima, Kota\|Kiyozumi, Yuki\|Uchihara, Tomoyuki\|Kurashige, Junji\|Iwatsuki, Masaaki\|Baba, Yoshifumi\|Sakamoto, Yasuo\|Miyamoto, Yuji\|Yoshida, Naoya\|Watanabe, Masayuki\|Goel, Ajay\|Tan, Patrick\|Baba,
PMID:	28699179

215.
Journal:	Gastroenterology. 2017 Oct;153(4):1040-1053.e4.
Title:	MET Signaling Mediates Intestinal Crypt-Villus Development, Regeneration, and Adenoma Formation and Is Promoted by Stem Cell CD44 Isoforms.
Author:	Joosten, Sander P J\|Zeilstra, Jurrit\|van Andel, Harmen\|Mijnals, R Clinton\|Zaunbrecher, Joost\|Duivenvoorden, Annet A M\|van de Wetering, Marc\|Clevers, Hans\|Spaargaren, Marcel\|Pals, Steven T
PMID:	28716720

216.
Journal:	J Biol Chem. 2017 Sep 8;292(36):14989-15001.
Title:	LGR5 receptor promotes cell-cell adhesion in stem cells and colon cancer cells via the IQGAP1-Rac1 pathway.
Author:	Carmon, Kendra S\|Gong, Xing\|Yi, Jing\|Wu, Ling\|Thomas, Anthony\|Moore, Catherine M\|Masuho, Ikuo\|Timson, David J\|Martemyanov, Kirill A\|Liu, Qingyun J
PMID:	28739799

217.
Journal:	Int J Mol Sci. 2017 Sep 1;18(9). pii: ijms18091888.
Title:	Bromopropane Compounds Increase the Stemness of Colorectal Cancer Cells.
Author:	Cho, Young-Chang\|Nguyen, Thanh Thi\|Park, So-Yeon\|Kim, Kwonseop\|Kim, Hyung Sik\|Jeong, Hye Gwang\|Kim, Kyung Keun\|Kim, Hangun
PMID:	28862656

218.
Journal:	Sci Rep. 2017 Sep 8;7(1):10939.
Title:	SATB2/beta-catenin/TCF-LEF pathway induces cellular transformation by generating cancer stem cells in colorectal cancer.
Author:	Yu, Wei\|Ma, Yiming\|Shankar, Sharmila\|Srivastava, Rakesh K
PMID:	28887549

219.
Journal:	Cancer Res. 2017 Dec 1;77(23):6589-6602.
Title:	R-Spondin1/LGR5 Activates TGFbeta Signaling and Suppresses Colon Cancer Metastasis.
Author:	Zhou, Xiaolin\|Geng, Liying\|Wang, Degeng\|Yi, Haowei\|Talmon, Geoffrey\|Wang, Jing
PMID:	28939678

220.
Journal:	Cancers (Basel). 2017 Oct 24;9(10). pii: cancers9100143.
Title:	Roles of microRNAs and RNA-Binding Proteins in the Regulation of Colorectal Cancer Stem Cells.
Author:	Mukohyama, Junko\|Shimono, Yohei\|Minami, Hironobu\|Kakeji, Yoshihiro\|Suzuki, Akira
PMID:	29064439

221.
Journal:	Pathology. 2017 Dec;49(7):721-730.
Title:	The prognostic value of cancer stem-like cell markers SOX2 and CD133 in stage III colon cancer is modified by expression of the immune-related markers FoxP3, PD-L1 and CD3.
Author:	Miller, T J\|McCoy, M J\|Hemmings, C\|Bulsara, M K\|Iacopetta, B\|Platell, C F
PMID:	29102042

222.
Journal:	Sci Rep. 2017 Nov 22;7(1):15992.
Title:	Metformin transiently inhibits colorectal cancer cell proliferation as a result of either AMPK activation or increased ROS production.
Author:	Mogavero, Angela\|Maiorana, Maria Valeria\|Zanutto, Susanna\|Varinelli, Luca\|Bozzi, Fabio\|Belfiore, Antonino\|Volpi, Chiara C\|Gloghini, Annunziata\|Pierotti, Marco A\|Gariboldi, Manuela
PMID:	29167573

223.
Journal:	Sci Rep. 2017 Dec 13;7(1):17488.
Title:	Small molecules related to adrenomedullin reduce tumor burden in a mouse model of colitis-associated colon cancer.
Author:	Ochoa-Callejero, Laura\|Garcia-Sanmartin, Josune\|Martinez-Herrero, Sonia\|Rubio-Mediavilla, Susana\|Narro-Iniguez, Judit\|Martinez, Alfredo
PMID:	29235493

224.
Journal:	Oncol Lett. 2017 Dec;14(6):7791-7798.
Title:	Leucine-rich repeat-containing G protein-coupled receptor 5 and CD133 expression is associated with tumor progression and resistance to preoperative chemoradiotherapy in low rectal cancer.
Author:	Harada, Yuzo\|Kazama, Shinsuke\|Morikawa, Teppei\|Murono, Koji\|Yasuda, Koji\|Otani, Kensuke\|Nishikawa, Takeshi\|Tanaka, Toshiaki\|Kiyomatsu, Tomomichi\|Kawai, Kazushige\|Hata, Keisuke\|Nozawa, Hiroaki\|Yamaguchi, Hironori\|Ishihara, Soichiro\|Watanabe, Toshiaki
PMID:	29250176

225.
Journal:	J Cell Physiol. 2018 Feb;233(2):727-735.
Title:	Overexpression of HOXA4 and HOXA9 genes promotes self-renewal and contributes to colon cancer stem cell overpopulation.
Author:	Bhatlekar, Seema\|Viswanathan, Vignesh\|Fields, Jeremy Z\|Boman, Bruce M
PMID:	28464221

226.
Journal:	Cell Signal. 2018 Jan;42:97-105.
Title:	Logarithmic expansion of LGR5(+) cells in human colorectal cancer.
Author:	Martin, Maria Laura\|Zeng, Zhaoshi\|Adileh, Mohammad\|Jacobo, Adrian\|Li, Christy\|Vakiani, Efsevia\|Hua, Guoqiang\|Zhang, Lixing\|Haimovitz-Friedman, Adriana\|Fuks, Zvi\|Kolesnick, Richard\|Paty, Philip B
PMID:	28958617

227.
Journal:	Br J Cancer. 2018 Feb 20;118(4):558-565.
Title:	LGR5 expression is regulated by EGF in early colorectal adenomas and governs EGFR inhibitor sensitivity.
Author:	Morgan, R G\|Mortensson, E\|Legge, D N\|Gupta, B\|Collard, T J\|Greenhough, A\|Williams, A C
PMID:	29149105

228.
Journal:	Biochem Biophys Res Commun. 2018 Feb 5;496(2):302-308.
Title:	miR-3120-5p promotes colon cancer stem cell stemness and invasiveness through targeting Axin2.
Author:	Hongdan, Li\|Feng, Li
PMID:	29307822

229.
Journal:	Int J Oncol. 2018 Mar;52(3):721-732.
Title:	CD133 expression predicts post-operative recurrence in patients with colon cancer with peritoneal metastasis.
Author:	Nagata, Hiroshi\|Ishihara, Soichiro\|Kishikawa, Junko\|Sonoda, Hirofumi\|Murono, Koji\|Emoto, Shigenobu\|Kaneko, Manabu\|Sasaki, Kazuhito\|Otani, Kensuke\|Nishikawa, Takeshi\|Tanaka, Toshiaki\|Kiyomatsu, Tomomichi\|Hata, Keisuke\|Kawai, Kazushige\|Nozawa, Hiroaki
PMID:	29328371

230.
Journal:	BMC Biol. 2018 Jan 10;16(1):3.
Title:	A role for endothelial nitric oxide synthase in intestinal stem cell proliferation and mesenchymal colorectal cancer.
Author:	Penarando, Jon\|Lopez-Sanchez, Laura M\|Mena, Rafael\|Guil-Luna, Silvia\|Conde, Francisco\|Hernandez, Vanessa\|Toledano, Marta\|Gudino, Victoria\|Raponi, Michela\|Billard, Caroline\|Villar, Carlos\|Diaz, Cesar\|Gomez-Barbadillo, Jose\|De la Haba-Rodriguez, Juan\|Myant,
PMID:	29329541

231.
Journal:	Oncogene. 2018 Mar;37(12):1669-1684.
Title:	Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers.
Author:	Solomon, Hilla\|Dinowitz, Nathan\|Pateras, Ioannis S\|Cooks, Tomer\|Shetzer, Yoav\|Molchadsky, Alina\|Charni, Meital\|Rabani, Stav\|Koifman, Gabriela\|Tarcic, Ohad\|Porat, Ziv\|Kogan-Sakin, Ira\|Goldfinger, Naomi\|Oren, Moshe\|Harris, Curtis C\|Gorgoulis, Vassilis G\|Rot
PMID:	29343849

232.
Journal:	Stem Cell Res Ther. 2018 Feb 2;9(1):26.
Title:	BCN057 induces intestinal stem cell repair and mitigates radiation-induced intestinal injury.
Author:	Bhanja, Payel\|Norris, Andrew\|Gupta-Saraf, Pooja\|Hoover, Andrew\|Saha, Subhrajit
PMID:	29394953

233.
Journal:	Cell Rep. 2018 Feb 6;22(6):1600-1614.
Title:	Specific Labeling of Stem Cell Activity in Human Colorectal Organoids Using an ASCL2-Responsive Minigene.
Author:	Oost, Koen C\|van Voorthuijsen, Lisa\|Fumagalli, Arianna\|Lindeboom, Rik G H\|Sprangers, Joep\|Omerzu, Manja\|Rodriguez-Colman, Maria J\|Heinz, Maria C\|Verlaan-Klink, Ingrid\|Maurice, Madelon M\|Burgering, Boudewijn M T\|van Rheenen, Jacco\|Vermeulen, Michiel\|Snippe
PMID:	29425513

234.
Journal:	Oncol Lett. 2018 Feb;15(2):2287-2295.
Title:	beta-catenin, leucine-rich repeat-containing G protein-coupled receptor 5 and GATA-binding factor 6 are associated with the normal mucosa-adenoma-adenocarcinoma sequence of colorectal tumorigenesis.
Author:	Yang, Bin\|Mao, Liang\|Li, Yan\|Li, Qia\|Li, Xioli\|Zhang, Yunjing\|Zhai, Zhenhua
PMID:	29434936

235.
Journal:	Oncol Rep. 2018 Apr;39(4):1930-1938.
Title:	Kynurenine promotes the goblet cell differentiation of HT-29 colon carcinoma cells by modulating Wnt, Notch and AhR signals.
Author:	Park, Joo-Hung\|Lee, Jeong-Min\|Lee, Eun-Jin\|Kim, Da-Jeong\|Hwang, Won-Bhin
PMID:	29436668

236.
Journal:	Sci Rep. 2018 Feb 20;8(1):3335.
Title:	Oligomeric proanthocyanidins (OPCs) target cancer stem-like cells and suppress tumor organoid formation in colorectal cancer.
Author:	Toden, Shusuke\|Ravindranathan, Preethi\|Gu, Jinghua\|Cardenas, Jacob\|Yuchang, Madelaine\|Goel, Ajay
PMID:	29463813

237.
Journal:	Development. 2018 Mar 14;145(6). pii: dev.153049.
Title:	Identification, isolation and characterization of human LGR5-positive colon adenoma cells.
Author:	Dame, Michael K\|Attili, Durga\|McClintock, Shannon D\|Dedhia, Priya H\|Ouillette, Peter\|Hardt, Olaf\|Chin, Alana M\|Xue, Xiang\|Laliberte, Julie\|Katz, Erica L\|Newsome, Gina M\|Hill, David R\|Miller, Alyssa J\|Tsai, Yu-Hwai\|Agorku, David\|Altheim, Christopher H\|Bosi
PMID:	29467240

238.
Journal:	Oncol Lett. 2018 Apr;15(4):5989-5994.
Title:	TROY is a promising prognostic biomarker in patients with colorectal cancer.
Author:	Nishioka, Mitsuaki\|Suehiro, Yutaka\|Sakai, Kouhei\|Matsumoto, Toshihiko\|Okayama, Naoko\|Mizuno, Hidekazu\|Ueno, Koji\|Suzuki, Nobuaki\|Hashimoto, Shinichi\|Takami, Taro\|Hazama, Shoichi\|Nagano, Hiroaki\|Sakaida, Isao\|Yamasaki, Takahiro
PMID:	29556315

239.
Journal:	Cell Physiol Biochem. 2018;46(2):860-872.
Title:	Lgr5+CD44+EpCAM+ Strictly Defines Cancer Stem Cells in Human Colorectal Cancer.
Author:	Leng, Zhengwei\|Xia, Qinghua\|Chen, Jinhuang\|Li, Yong\|Xu, Jiqian\|Zhao, Ende\|Zheng, Hai\|Ai, Walden\|Dong, Jiangchuan
PMID:	29627827

240.
Journal:	Cancer Lett. 2018 Aug 1;428:1-11.
Title:	Jade family PHD finger 3 (JADE3) increases cancer stem cell-like properties and tumorigenicity in colon cancer.
Author:	Jian, Yunting\|Wang, Meng\|Zhang, Yan\|Ou, Ruizhang\|Zhu, Ziyuan\|Ou, Yangying\|Chen, Xiangfu\|Liang, Xin\|Ding, Yanqing\|Song, Libing\|Xu, Xuehu\|Liao, Wenting
PMID:	29660380

241.
Journal:	Mol Pharm. 2018 Jun 4;15(6):2448-2454.
Title:	Evaluation of Anti-LGR5 Antibodies by ImmunoPET for Imaging Colorectal Tumors and Development of Antibody-Drug Conjugates.
Author:	Azhdarinia, Ali\|Voss, Julie\|Ghosh, Sukhen C\|Simien, Jo A\|Hernandez Vargas, Servando\|Cui, Jie\|Yu, Wangsheng A\|Liu, Qingyun\|Carmon, Kendra S
PMID:	29718672

242.
Journal:	Int J Mol Med. 2018 Aug;42(2):713-725.
Title:	Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review).
Author:	Katoh, Masaru
PMID:	29786110

243.
Journal:	Br J Cancer. 2018 May;118(11):1410-1418.
Title:	Targeting LGR5 in Colorectal Cancer: therapeutic gold or too plastic?
Author:	Morgan, R G\|Mortensson, E\|Williams, A C
PMID:	29844449

244.
Journal:	Sci China Life Sci. 2018 Jul;61(7):800-807.
Title:	BMP signaling in homeostasis, transformation and inflammatory response of intestinal epithelium.
Author:	Wang, Shan\|Chen, Ye-Guang
PMID:	29855793

245.
Journal:	Cancer Sci. 2018 Aug;109(8):2479-2489.
Title:	DEAD box protein DDX1 promotes colorectal tumorigenesis through transcriptional activation of the LGR5 gene.
Author:	Tanaka, Kiyoko\|Ikeda, Narumi\|Miyashita, Kazuya\|Nuriya, Hideko\|Hara, Takahiko
PMID:	29869821

246.
Journal:	Clin Colorectal Cancer. 2018 Sep;17(3):e579-e592.
Title:	Cancer Stemness, Immune Cells, and Epithelial-Mesenchymal Transition Cooperatively Predict Prognosis in Colorectal Carcinoma.
Author:	Xu, Fangying\|Li, Si\|Zhang, Jing\|Wang, Lili\|Wu, Xuesong\|Wang, Jing\|Huang, Qiong\|Lai, Maode
PMID:	29921496

247.
Journal:	Cell Oncol (Dordr). 2018 Oct;41(5):495-504.
Title:	Mesenchymal marker and LGR5 expression levels in circulating tumor cells correlate with colorectal cancer prognosis.
Author:	Wang, Wuyi\|Wan, Lin\|Wu, Shiyang\|Yang, Jianguo\|Zhou, Yang\|Liu, Fang\|Wu, Zhengzheng\|Cheng, Yong
PMID:	29949050

248.
Journal:	Mol Med Rep. 2018 Aug;18(2):2269-2276.
Title:	LncRNA CASC15 promotes colon cancer cell proliferation and metastasis by regulating the miR4310/LGR5/Wnt/betacatenin signaling pathway.
Author:	Jing, Niancai\|Huang, Tao\|Guo, Huaiyu\|Yang, Jili\|Li, Mingjing\|Chen, Zhuo\|Zhang, Yue
PMID:	29956772

249.
Journal:	Cell Death Dis. 2018 Jul 3;9(7):739.
Title:	PIK3CA mutations confer resistance to first-line chemotherapy in colorectal cancer.
Author:	Wang, Qiang\|Shi, Yan-Long\|Zhou, Kai\|Wang, Li-Li\|Yan, Ze-Xuan\|Liu, Yu-Lin\|Xu, Li-Li\|Zhao, Shi-Wei\|Chu, Hui-Li\|Shi, Ting-Ting\|Ma, Qing-Hua\|Bi, Jingwang
PMID:	29970892

250.
Journal:	Open Access Maced J Med Sci. 2018 Jun 7;6(6):968-974.
Title:	Colonic Stem Cells Expression of Lgr5 and CD133 Proteins as Predictive Markers in Colorectal Cancer among Egyptian Patients.
Author:	Rosiq, Saed\|Hammam, Olfat\|Abdelalim, Ahmed\|Anas, Amgad\|Khalil, Heba\|Amer, Mosbah
PMID:	29983786

251.
Journal:	Stem Cell Reports. 2018 Aug 14;11(2):410-424.
Title:	The Zinc Finger Transcription Factor PLAGL2 Enhances Stem Cell Fate and Activates Expression of ASCL2 in Intestinal Epithelial Cells.
Author:	Strubberg, Ashlee M\|Veronese Paniagua, Daniel A\|Zhao, Tingting\|Dublin, Leeran\|Pritchard, Thomas\|Bayguinov, Peter O\|Fitzpatrick, James A J\|Madison, Blair B
PMID:	30017821

252.
Journal:	Am J Pathol. 2018 Oct;188(10):2236-2250.
Title:	Expression Profile of LGR5 and Its Prognostic Significance in Colorectal Cancer Progression.
Author:	Jang, Bo Gun\|Kim, Hye Sung\|Chang, Weon Young\|Bae, Jeong Mo\|Kim, Woo Ho\|Kang, Gyeong Hoon
PMID:	30036518

253.
Journal:	Oncotarget. 2018 Jul 10;9(53):30025-30033.
Title:	Heterogeneous expression of Lgr5 as a risk factor for focal invasion and distant metastasis of colorectal carcinoma.
Author:	Zheng, Zhong\|Yu, Huiping\|Huang, Qin\|Wu, Hongyan\|Fu, Yao\|Shi, Jiong\|Wang, Ting\|Fan, Xiangshan
PMID:	30046385

254.
Journal:	Cancer Res. 2018 Aug 28. pii: 0008-5472.CAN-18-0451.
Title:	Transcription factor PROX1 suppresses Notch pathway activation via the nucleosome remodeling and deacetylase complex in colorectal cancer stem-like cells.
Author:	Hogstrom, Jenny\|Heino, Sarika\|Kallio, Pauliina\|Lahde, Marianne\|Leppanen, Veli-Matti\|Balboa, Diego\|Wiener, Zoltan\|Alitalo, Kari
PMID:	30154153

255.
Journal:	J Exp Clin Cancer Res. 2018 Sep 12;37(1):225.
Title:	LGR5, a novel functional glioma stem cell marker, promotes EMT by activating the Wnt/beta-catenin pathway and predicts poor survival of glioma patients.
Author:	Zhang, Jin\|Cai, Hongqing\|Sun, Lixin\|Zhan, Panpan\|Chen, Meng\|Zhang, Feng\|Ran, Yuliang\|Wan, Jinghai
PMID:	30208924

256.
Journal:	Adv Biomed Res. 2018 Aug 31;7:125.
Title:	Leucine-rich Repeat-containing G-protein Coupled Receptor 5 Gene Overexpression of the Rat Small Intestinal Progenitor Cells in Response to Orally Administered Grape Exosome-like Nanovesicles.
Author:	Rahimi Ghiasi, Moosa\|Rahimi, Elnaz\|Amirkhani, Zohreh\|Salehi, Rasoul
PMID:	30211138

257.
Journal:	Br J Cancer. 2018 Sep 17. pii: 10.1038/s41416-018-0254-z.
Title:	Exosomes from BM-MSCs increase the population of CSCs via transfer of miR-142-3p.
Author:	Li, Hongdan\|Li, Feng
PMID:	30220706

258.
Journal:	Nat Cell Biol. 2018 Oct;20(10):1134-1144.
Title:	LncGata6 maintains stemness of intestinal stem cells and promotes intestinal tumorigenesis.
Author:	Zhu, Pingping\|Wu, Jiayi\|Wang, Yanying\|Zhu, Xiaoxiao\|Lu, Tiankun\|Liu, Benyu\|He, Luyun\|Ye, Buqing\|Wang, Shuo\|Meng, Shu\|Fan, Dongdong\|Wang, Jing\|Yang, Liuliu\|Qin, Xiwen\|Du, Ying\|Li, Chong\|He, Lei\|Ren, Weizheng\|Wu, Xin\|Tian, Yong\|Fan, Zusen
PMID:	30224759

259.
Journal:	Eur J Cancer Prev. 2018 Sep 18.
Title:	Establishment of a multicomponent dietary bioactive human equivalent dose to delete damaged Lgr5+ stem cells using a mouse colon tumor initiation model.
Author:	Kim, Eunjoo\|Wright, Gus A\|Zoh, Roger S\|Patil, Bhimanagouda S\|Jayaprakasha, Guddadarangavvanahally K\|Callaway, Evelyn S\|Ivanov, Ivan\|Turner, Nancy D\|Chapkin, Robert S
PMID:	30234553

260.
Journal:	Mol Cancer Res. 2018 Sep 26. pii: 1541-7786.MCR-18-0054.
Title:	Oncogenic STRAP Supports Hepatocellular Carcinoma Growth by Enhancing Wnt/beta-Catenin Signaling.
Author:	Wang, Wenhui\|Li, Shan\|Liu, Pengyu\|Sideras, Kostandinos\|van de Werken, Harmen J G\|van der Heide, Marieke\|Cao, Wanlu\|Lavrijsen, Marla\|Peppelenbosch, Maikel P\|Bruno, Marco\|Pan, Qiuwei\|Smits, Ron
PMID:	30257989

261.
Journal:	Int J Oncol. 2018 Sep 18.
Title:	Characterisation of mesenchymal colon tumour-derived cells in tumourspheres as a model for colorectal cancer progression.
Author:	Turano, Mimmo\|Costabile, Valeria\|Cerasuolo, Andrea\|Duraturo, Francesca\|Liccardo, Raffaella\|Delrio, Paolo\|Pace, Ugo\|Rega, Daniela\|Dodaro, Concetta Anna\|Milone, Marco\|Izzo, Paola\|De Rosa, Marina
PMID:	30272331

262.
Journal:	Oncotarget. 2017 Dec 22;9(70):33403-33415.
Title:	Cancer stem cells in progression of colorectal cancer.
Author:	Zhou, Yujuan\|Xia, Longzheng\|Wang, Heran\|Oyang, Linda\|Su, Min\|Liu, Qiang\|Lin, Jingguan\|Tan, Shiming\|Tian, Yutong\|Liao, Qianjin\|Cao, Deliang
PMID:	30279970

263.
Journal:	Zhonghua Yi Xue Za Zhi. 2018 Sep 25;98(36):2899-2904.
Title:	[Expression of stem cell markers CD44 and Lgr5 in colorectal cancer and its relationship with lymph node and liver metastasis].
Author:	Wang, X F\|Zhang, X L\|Xu, L P\|Shi, G G\|Zheng, H Y\|Sun, B C
PMID:	30293346

264.
Journal:	Onco Targets Ther. 2018 Oct 4;11:6437-6446.
Title:	Radix Tetrastigma hemsleyani flavone exhibits antitumor activity in colorectal cancer via Wnt/beta-catenin signaling pathway.
Author:	Wu, Xiaowei\|Yu, Na\|Zhang, Yuping\|Ye, Yuanning\|Sun, Wenrong\|Ye, Lei\|Wu, Huimin\|Yang, Zhao\|Wu, Lin\|Wang, Fangyu
PMID:	30323621

265.
Journal:	Mol Cancer Ther. 2018 Oct 18. pii: 1535-7163.MCT-18-0104.
Title:	A Unique Non-Saccharide Mimetic of Heparin Hexasaccharide Inhibits Colon Cancer Stem Cells via p38 MAP Kinase Activation.
Author:	Boothello, Rio S\|Patel, Nirmita J\|Sharon, Chetna\|Abdelfadiel, Elsamani I\|Morla, Shravan\|Brophy, Donald F\|Lippman, H Robert\|Desai, Umesh R\|Patel, Bhaumik B
PMID:	30337351

266.
Journal:	Oncotarget. 2018 Sep 21;9(74):33982-33994.
Title:	Sulforaphane inhibits growth and blocks Wnt/beta-catenin signaling of colorectal cancer cells.
Author:	Bernkopf, Dominic B\|Daum, Gabriele\|Bruckner, Martina\|Behrens, Jurgen
PMID:	30338040

267.
Journal:	Gastroenterology. 2018 Oct 23. pii: S0016-5085(18)35163-1.
Title:	TRIB3 Interacts with Beta-catenin and TCF4 to Increase Stem Cell Features of Colorectal Cancer Stem Cells and Tumorigenesis.
Author:	Hua, Fang\|Shang, Shuang\|Yang, Yu-Wei\|Zhang, Hai-Zeng\|Xu, Tian-Lei\|Yu, Jiao-Jiao\|Zhou, Dan-Dan\|Cui, Bing\|Li, Ke\|Lv, Xiao-Xi\|Zhang, Xiao-Wei\|Liu, Shan-Shan\|Yu, Jin-Mei\|Wang, Feng\|Zhang, Cheng\|Huang, Bo\|Hu, Zhuo-Wei
PMID:	30365932