Primary Site >> Colorectal Cancer

Gene >> LGALS4

Journal: Mol Cell Biol. 1995 May;15(5):2490-9.
Title: An Sp1 binding site and the minimal promoter contribute to overexpression of the cytokeratin 18 gene in tumorigenic clones relative to that in nontumorigenic clones of a human carcinoma cell line.
Author: Gunther, M|Frebourg, T|Laithier, M|Fossar, N|Bouziane-Ouartini, M|Lavialle, C|Brison, O
PMID: 7537848
Journal: Eur J Biochem. 1997 Aug 15;248(1):225-30.
Title: Cloning and expression of the mRNA of human galectin-4, an S-type lectin down-regulated in colorectal cancer.
Author: Rechreche, H|Mallo, G V|Montalto, G|Dagorn, J C|Iovanna, J L
PMID: 9310382
Journal: J Cell Biol. 1998 Jun 15;141(6):1433-48.
Title: Differential nuclear translocation and transactivation potential of beta-catenin and plakoglobin.
Author: Simcha, I|Shtutman, M|Salomon, D|Zhurinsky, J|Sadot, E|Geiger, B|Ben-Ze'ev, A
PMID: 9628899
Journal: Int J Cancer. 1998 May 29;76(5):652-8.
Title: Characterization of human colon cancer antigens recognized by autologous antibodies.
Author: Scanlan, M J|Chen, Y T|Williamson, B|Gure, A O|Stockert, E|Gordan, J D|Tureci, O|Sahin, U|Pfreundschuh, M|Old, L J
PMID: 9610721
Journal: Cancer Res. 2001 Feb 1;61(3):854-8.
Title: A mammalian two-hybrid system for adenomatous polyposis coli-mutated colon cancer therapeutics.
Author: Wakita, K|Tetsu, O|McCormick, F
PMID: 11221869
Journal: J Cancer Res Clin Oncol. 2001;127(6):375-86.
Title: Comprehensive galectin fingerprinting in a panel of 61 human tumor cell lines by RT-PCR and its implications for diagnostic and therapeutic procedures.
Author: Lahm, H|Andre, S|Hoeflich, A|Fischer, J R|Sordat, B|Kaltner, H|Wolf, E|Gabius, H J
PMID: 11414198
Journal: Nucleic Acids Res. 2002 Aug 1;30(15):3312-22.
Title: Transcriptional deregulation of the keratin 18 gene in human colon carcinoma cells results from an altered acetylation mechanism.
Author: Prochasson, Philippe|Delouis, Cecile|Brison, Olivier
PMID: 12140315
Journal: Anticancer Res. 2002 Nov-Dec;22(6A):3285-92.
Title: Amplified Muc1-specific gene expression in colon cancer cells utilizing a binary system in adenoviral vectors.
Author: Block, Andreas|Milasinovic, Dragan|Mueller, Juergen|Schaefer, Peter|Schaefer, Hansjoerg|Greten, Heiner
PMID: 12530077
Journal: Cancer Lett. 2003 Apr 25;193(2):161-70.
Title: Tyrosine kinase inhibitor STI-571/Gleevec down-regulates the beta-catenin signaling activity.
Author: Zhou, Lan|An, Naili|Haydon, Rex C|Zhou, Qixin|Cheng, Hongwei|Peng, Ying|Jiang, Wei|Luu, Hue H|Vanichakarn, Pantila|Szatkowski, Jan Paul|Park, Jae Yoon|Breyer, Benjamin|He, Tong-Chuan
PMID: 12706873
Journal: Am J Physiol Gastrointest Liver Physiol. 2003 Nov;285(5):G919-28. Epub 2003 Jul
Title: 5,6-Dichloro-ribifuranosylbenzimidazole- and apigenin-induced sensitization of colon cancer cells to TNF-alpha-mediated apoptosis.
Author: Farah, Myriam|Parhar, Kuljit|Moussavi, Maryam|Eivemark, Sharlene|Salh, Baljinder
PMID: 12842827
Journal: J Biol Chem. 2003 Aug 15;278(33):30425-8. Epub 2003 Jul 2.
Title: Presenilin-dependent "gamma-secretase" processing of deleted in colorectal cancer (DCC).
Author: Taniguchi, Yoshihito|Kim, Seong-Hun|Sisodia, Sangram S
PMID: 12840034
Journal: Cancer. 2003 Apr 15;97(8):1849-58.
Title: Refined prognostic evaluation in colon carcinoma using immunohistochemical galectin fingerprinting.
Author: Nagy, Nathalie|Legendre, Hugues|Engels, Olivier|Andre, Sabine|Kaltner, Herbert|Wasano, Kojiro|Zick, Yehiel|Pector, Jean-Claude|Decaestecker, Christine|Gabius, Hans-Joachim|Salmon, Isabelle|Kiss, Robert
PMID: 12673710
Journal: Nucleic Acids Res. 2003 Mar 15;31(6):1693-703.
Title: Histone deacetylase inhibitors stimulate mitochondrial HMG-CoA synthase gene expression via a promoter proximal Sp1 site.
Author: Camarero, Nuria|Nadal, Alicia|Barrero, Maria Jose|Haro, Diego|Marrero, Pedro F
PMID: 12626711
Journal: Cancer Sci. 2004 Jan;95(1):52-7.
Title: Nemo-like kinase suppresses a wide range of transcription factors, including nuclear factor-kappaB.
Author: Yasuda, Jun|Yokoo, Hideki|Yamada, Tesshi|Kitabayashi, Issay|Sekiya, Takao|Ichikawa, Hitoshi
PMID: 14720327
Journal: Glycoconj J. 2004;20(4):227-38.
Title: Tumor galectinology: insights into the complex network of a family of endogenous lectins.
Author: Lahm, Harald|Andre, Sabine|Hoeflich, Andreas|Kaltner, Herbert|Siebert, Hans-Christian|Sordat, Bernard|von der Lieth, Claus-Wilhelm|Wolf, Eckhard|Gabius, Hans-Joachim
PMID: 15115907
Journal: Int J Oncol. 2004 Oct;25(4):1049-56.
Title: Search for epithelial-specific mRNAs in peripheral blood of patients with colon cancer by RT-PCR.
Author: Solmi, Rossella|De Sanctis, Paola|Zucchini, Cinzia|Ugolini, Giampaolo|Rosati, Giancarlo|Del Governatore, Marco|Coppola, Domenico|Yeatman, Thymothy J|Lenzi, Luca|Caira, Antonello|Zanotti, Simone|Taffurelli, Mario|Carinci, Paolo|Valvassori, Luisa|Strippoli,
PMID: 15375555
Journal: Mol Pharmacol. 2005 Jul;68(1):119-28.
Title: 2-Cyano-3,12-dioxoolean-1,9-dien-28-oic acid and related compounds inhibit growth of colon cancer cells through peroxisome proliferator-activated receptor gamma-dependent and -independent pathways.
Author: Chintharlapalli, Sudhakar|Papineni, Sabitha|Konopleva, Marina|Andreef, Michael|Samudio, Ismael|Safe, Stephen
PMID: 15798084
Journal: Endocr Pathol. 2006 Fall;17(3):243-9.
Title: Galectin-4 expression in carcinoid tumors.
Author: Rumilla, Kandelaria M|Erickson, Lori A|Erickson, Alan K|Lloyd, Ricardo V
PMID: 17308361
Journal: J Cell Physiol. 2006 May;207(2):287-92.
Title: Repression of HIP/RPL29 expression induces differentiation in colon cancer cells.
Author: Liu, Jian-Jun|Huang, Bao Hua|Zhang, Jinqiu|Carson, Daniel D|Hooi, Shing Chuan
PMID: 16475173
Journal: Biochem Biophys Res Commun. 2006 Feb 17;340(3):758-66.
Title: Elevated expression and potential roles of human Sp5, a member of Sp transcription factor family, in human cancers.
Author: Chen, Yongxin|Guo, Yingqiu|Ge, Xijin|Itoh, Hirotaka|Watanabe, Akira|Fujiwara, Takeshi|Kodama, Tatsuhiko|Aburatani, Hiroyuki
PMID: 16380080
Journal: Oncol Rep. 2006 Oct;16(4):747-54.
Title: Differential expression in normal-adenoma-carcinoma sequence suggests complex molecular carcinogenesis in colon.
Author: Lee, Seungkoo|Bang, Seunghyun|Song, Kyuyoung|Lee, Inchul
PMID: 16969489
Journal: Oncogene. 2008 Aug 28;27(37):5075-80.
Title: Snail promotes Wnt target gene expression and interacts with beta-catenin.
Author: Stemmer, V|de Craene, B|Berx, G|Behrens, J
PMID: 18469861
Journal: Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Jul 1;64(Pt 7):665-7.
Title: Crystallization and preliminary X-ray diffraction analysis of mouse galectin-4 N-terminal carbohydrate recognition domain in complex with lactose.
Author: Krejcirikova, Veronika|Fabry, Milan|Markova, Vladimira|Maly, Petr|Rezacova, Pavlina|Brynda, Jiri
PMID: 18607104
Journal: Int J Cancer. 2011 Aug 15;129(4):799-809.
Title: Galectin-4 functions as a tumor suppressor of human colorectal cancer.
Author: Satelli, Arun|Rao, Prema S|Thirumala, Seshadri|Rao, U Subrahmanyeswara
PMID: 21064109
Journal: Oncol Rep. 2011 May;25(5):1217-26.
Title: Clinical significance of circulating galectins as colorectal cancer markers.
Author: Watanabe, Makoto|Takemasa, Ichiro|Kaneko, Naoki|Yokoyama, Yuhki|Matsuo, Ei-Ichi|Iwasa, Susumu|Mori, Masaki|Matsuura, Nariaki|Monden, Morito|Nishimura, Osamu
PMID: 21369702
Journal: J Neurosci. 2012 Mar 28;32(13):4440-56.
Title: Netrin/DCC signaling guides olfactory sensory axons to their correct location in the olfactory bulb.
Author: Lakhina, Vanisha|Marcaccio, Christina L|Shao, Xin|Lush, Mark E|Jain, Roshan A|Fujimoto, Esther|Bonkowsky, Joshua L|Granato, Michael|Raper, Jonathan A
PMID: 22457493
Journal: Cell Oncol (Dordr). 2013 Apr;36(2):169-78.
Title: Abrogation of galectin-4 expression promotes tumorigenesis in colorectal cancer.
Author: Kim, Seung Won|Park, Ki Cheong|Jeon, Soung Min|Ohn, Tak Bum|Kim, Tae Il|Kim, Won Ho|Cheon, Jae Hee
PMID: 23378274
Journal: J Nutr Biochem. 2014 Nov;25(11):1196-1206.
Title: Inherited cancer predisposition sensitizes colonic mucosa to address Western diet effects and putative cancer-predisposing changes on mouse proteome.
Author: Dermadi, Denis|Valo, Satu|Pussila, Marjaana|Reyhani, Nima|Sarantaus, Laura|Lalowski, Maciej|Baumann, Marc|Nystrom, Minna
PMID: 25172634
Journal: J Immunol Methods. 2015 Jan;416:59-68.
Title: Surface profiles of live colorectal cancer cells and tumor infiltrating lymphocytes from surgical samples correspond to prognostic categories.
Author: Zhou, Jerry|Belov, Larissa|Chapuis, Pierre|Chan, Charles|Armstrong, Nicola|Kaufman, Kimberley L|Solomon, Michael J|Clarke, Stephen J|Christopherson, Richard I
PMID: 25445327
Journal: Mutagenesis. 2016 Jul;31(4):401-8.
Title: Promoter SNPs rs116896264 and rs73933062 form a distinct haplotype and are associated with galectin-4 overexpression in colorectal cancer.
Author: Helwa, Reham|Ramadan, Mohamed|Abdel-Wahab, Abdel-Hady A|Knappskog, Stian|Bauer, Andrea S
PMID: 26681582
Journal: Oncotarget. 2016 May 24;7(21):30295-306.
Title: Systematic large-scale meta-analysis identifies a panel of two mRNAs as blood biomarkers for colorectal cancer detection.
Author: Rodia, Maria Teresa|Ugolini, Giampaolo|Mattei, Gabriella|Montroni, Isacco|Zattoni, Davide|Ghignone, Federico|Veronese, Giacomo|Marisi, Giorgia|Lauriola, Mattia|Strippoli, Pierluigi|Solmi, Rossella
PMID: 26993598
Journal: J Proteome Res. 2016 Dec 2;15(12):4412-4422.
Title: Detection of Proteome Changes in Human Colon Cancer Induced by Cell Surface Binding of Growth-Inhibitory Human Galectin-4 Using Quantitative SILAC-Based Proteomics.
Author: Michalak, Malwina|Warnken, Uwe|Andre, Sabine|Schnolzer, Martina|Gabius, Hans-Joachim|Kopitz, Juergen
PMID: 27801591
Journal: Chin Clin Oncol. 2016 Dec;5(6):76.
Title: Metallothionein 2A an interactive protein linking phosphorylated FADD to NF-kappaB pathway leads to colorectal cancer formation.
Author: Marikar, Faiz M M T|Jin, Guanghui|Sheng, Wang|Ma, Dingyuan|Hua, Zichun
PMID: 28061540
Journal: J Steroid Biochem Mol Biol. 2017 Oct;173:130-138.
Title: Integrative genomic approaches to dissect clinically-significant relationships between the VDR cistrome and gene expression in primary colon cancer.
Author: Long, Mark D|Campbell, Moray J
PMID: 28027912
Journal: Tumour Biol. 2017 Mar;39(3):1010428317691687.
Title: Surface-bound galectin-4 regulates gene transcription and secretion of chemokines in human colorectal cancer cell lines.
Author: Rao, U Subrahmanyeswara|Rao, Prema S
PMID: 28345468
Journal: Oncotarget. 2017 Apr 4;8(14):23787-23802.
Title: Promoter hypermethylation of LGALS4 correlates with poor prognosis in patients with urothelial carcinoma.
Author: Wu, Meei-Maan|Li, Ching-Fei|Lin, Li-Fang|Wang, Alexander Sheng-Shin|Pu, Yeong-Shiau|Wang, Hsiu-Hua|Mar, Ai-Chung|Chen, Chien-Jen|Lee, Te-Chang
PMID: 28423602
Journal: Clin Colorectal Cancer. 2018 Jun;17(2):e217-e228.
Title: LGALS4, CEACAM6, TSPAN8, and COL1A2: Blood Markers for Colorectal Cancer-Validation in a Cohort of Subjects With Positive Fecal Immunochemical Test Result.
Author: Rodia, Maria Teresa|Solmi, Rossella|Pasini, Francesco|Nardi, Elena|Mattei, Gabriella|Ugolini, Giampaolo|Ricciardiello, Luigi|Strippoli, Pierluigi|Miglio, Rossella|Lauriola, Mattia
PMID: 29352642