Primary Site >> Colorectal Cancer
Gene >> LGALS4
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Ref: An Sp1 binding site and the minimal promoter contribute to overexpression of the cytokeratin 18 gene in tumorigenic clones relative to that in nontumorigenic clones of a human carcinoma cell line. PMID: 7537848 |
Ref: Cloning and expression of the mRNA of human galectin-4, an S-type lectin down-regulated in colorectal cancer. PMID: 9310382 |
Ref: Characterization of human colon cancer antigens recognized by autologous antibodies. PMID: 9610721 Ref: Differential nuclear translocation and transactivation potential of beta-catenin and plakoglobin. PMID: 9628899 |
Ref: A mammalian two-hybrid system for adenomatous polyposis coli-mutated colon cancer therapeutics. PMID: 11221869 Ref: Comprehensive galectin fingerprinting in a panel of 61 human tumor cell lines by RT-PCR and its implications for diagnostic and therapeutic procedures. PMID: 11414198 |
Ref: Transcriptional deregulation of the keratin 18 gene in human colon carcinoma cells results from an altered acetylation mechanism. PMID: 12140315 Ref: Amplified Muc1-specific gene expression in colon cancer cells utilizing a binary system in adenoviral vectors. PMID: 12530077 |
Ref: Histone deacetylase inhibitors stimulate mitochondrial HMG-CoA synthase gene expression via a promoter proximal Sp1 site. PMID: 12626711 Ref: Refined prognostic evaluation in colon carcinoma using immunohistochemical galectin fingerprinting. PMID: 12673710 Ref: Tyrosine kinase inhibitor STI-571/Gleevec down-regulates the beta-catenin signaling activity. PMID: 12706873 Ref: Presenilin-dependent "gamma-secretase" processing of deleted in colorectal cancer (DCC). PMID: 12840034 Ref: 5,6-Dichloro-ribifuranosylbenzimidazole- and apigenin-induced sensitization of colon cancer cells to TNF-alpha-mediated apoptosis. PMID: 12842827 |
Ref: Nemo-like kinase suppresses a wide range of transcription factors, including nuclear factor-kappaB. PMID: 14720327 Ref: Tumor galectinology: insights into the complex network of a family of endogenous lectins. PMID: 15115907 Ref: Search for epithelial-specific mRNAs in peripheral blood of patients with colon cancer by RT-PCR. PMID: 15375555 |
Ref: 2-Cyano-3,12-dioxoolean-1,9-dien-28-oic acid and related compounds inhibit growth of colon cancer cells through peroxisome proliferator-activated receptor gamma-dependent and -independent pathways. PMID: 15798084 |
Ref: Elevated expression and potential roles of human Sp5, a member of Sp transcription factor family, in human cancers. PMID: 16380080 Ref: Repression of HIP/RPL29 expression induces differentiation in colon cancer cells. PMID: 16475173 Ref: Differential expression in normal-adenoma-carcinoma sequence suggests complex molecular carcinogenesis in colon. PMID: 16969489 Ref: Galectin-4 expression in carcinoid tumors. PMID: 17308361 |
Ref: Snail promotes Wnt target gene expression and interacts with beta-catenin. PMID: 18469861 Ref: Crystallization and preliminary X-ray diffraction analysis of mouse galectin-4 N-terminal carbohydrate recognition domain in complex with lactose. PMID: 18607104 |
Ref: Galectin-4 functions as a tumor suppressor of human colorectal cancer. PMID: 21064109 Ref: Clinical significance of circulating galectins as colorectal cancer markers. PMID: 21369702 |
Ref: Netrin/DCC signaling guides olfactory sensory axons to their correct location in the olfactory bulb. PMID: 22457493 |
Ref: Abrogation of galectin-4 expression promotes tumorigenesis in colorectal cancer. PMID: 23378274 |
Ref: Inherited cancer predisposition sensitizes colonic mucosa to address Western diet effects and putative cancer-predisposing changes on mouse proteome. PMID: 25172634 |
Ref: Surface profiles of live colorectal cancer cells and tumor infiltrating lymphocytes from surgical samples correspond to prognostic categories. PMID: 25445327 |
Ref: Promoter SNPs rs116896264 and rs73933062 form a distinct haplotype and are associated with galectin-4 overexpression in colorectal cancer. PMID: 26681582 Ref: Systematic large-scale meta-analysis identifies a panel of two mRNAs as blood biomarkers for colorectal cancer detection. PMID: 26993598 Ref: Detection of Proteome Changes in Human Colon Cancer Induced by Cell Surface Binding of Growth-Inhibitory Human Galectin-4 Using Quantitative SILAC-Based Proteomics. PMID: 27801591 Ref: Metallothionein 2A an interactive protein linking phosphorylated FADD to NF-kappaB pathway leads to colorectal cancer formation. PMID: 28061540 |
Ref: Integrative genomic approaches to dissect clinically-significant relationships between the VDR cistrome and gene expression in primary colon cancer. PMID: 28027912 Ref: Surface-bound galectin-4 regulates gene transcription and secretion of chemokines in human colorectal cancer cell lines. PMID: 28345468 Ref: Promoter hypermethylation of LGALS4 correlates with poor prognosis in patients with urothelial carcinoma. PMID: 28423602 |
Ref: LGALS4, CEACAM6, TSPAN8, and COL1A2: Blood Markers for Colorectal Cancer-Validation in a Cohort of Subjects With Positive Fecal Immunochemical Test Result. PMID: 29352642 |