Primary Site >> Pancreatic Cancer

Gene >> LGALS3

Journal: Int J Pancreatol. 1998 Feb;23(1):1-9.
Title: Localization of galectin-3 in normal and diseased pancreatic tissue.
Author: Schaffert, C|Pour, P M|Chaney, W G
PMID: 9520085
Journal: Carcinogenesis. 2000 Jun;21(6):1121-7.
Title: Biologic instability of pancreatic cancer xenografts in the nude mouse.
Author: Schmied, B M|Ulrich, A B|Matsuzaki, H|El-Metwally, T H|Ding, X|Fernandes, M E|Adrian, T E|Chaney, W G|Batra, S K|Pour, P M
PMID: 10836999
Journal: J Histochem Cytochem. 2001 Apr;49(4):539-49.
Title: Comparative analysis of galectins in primary tumors and tumor metastasis in human pancreatic cancer.
Author: Berberat, P O|Friess, H|Wang, L|Zhu, Z|Bley, T|Frigeri, L|Zimmermann, A|Buchler, M W
PMID: 11259457
Journal: Cancer. 2002 Jan 1;94(1):228-39.
Title: Influences of the lysosomal associated membrane proteins (Lamp-1, Lamp-2) and Mac-2 binding protein (Mac-2-BP) on the prognosis of pancreatic carcinoma.
Author: Kunzli, Beat M|Berberat, Pascal O|Zhu, Zhaowhen W|Martignoni, Marcus|Kleeff, Jorg|Tempia-Caliera, Adrien A|Fukuda, Minoru|Zimmermann, Arthur|Friess, Helmut|Buchler, Markus W
PMID: 11815981
Journal: Am J Pathol. 2002 May;160(5):1745-54.
Title: Characterization of gene expression profiles in intraductal papillary-mucinous tumors of the pancreas.
Author: Terris, Benoit|Blaveri, Ekaterina|Crnogorac-Jurcevic, Tatjana|Jones, Melanie|Missiaglia, Edoardo|Ruszniewski, Philippe|Sauvanet, Alain|Lemoine, Nicholas R
PMID: 12000726
Journal: Neoplasia. 2004 Sep-Oct;6(5):611-22.
Title: Gene expression profiling of microdissected pancreatic ductal carcinomas using high-density DNA microarrays.
Author: Grutzmann, Robert|Pilarsky, Christian|Ammerpohl, Ole|Luttges, Jutta|Bohme, Armin|Sipos, Bence|Foerder, Melanie|Alldinger, Ingo|Jahnke, Beatrix|Schackert, Hans Konrad|Kalthoff, Holger|Kremer, Bernd|Kloppel, Gunter|Saeger, Hans Detlev
PMID: 15548371
Journal: World J Gastroenterol. 2008 Apr 7;14(13):2023-8.
Title: Pancreatic stellate cells promote proliferation and invasiveness of human pancreatic cancer cells via galectin-3.
Author: Jiang, Hai-Biao|Xu, Ming|Wang, Xing-Peng
PMID: 18395901
Journal: Mol Cancer Ther. 2008 Oct;7(10):3275-84.
Title: Antitumor activity and molecular effects of the novel heat shock protein 90 inhibitor, IPI-504, in pancreatic cancer.
Author: Song, Dongweon|Chaerkady, Raghothama|Tan, Aik Choon|Garcia-Garcia, Elena|Nalli, Anuradha|Suarez-Gauthier, Ana|Lopez-Rios, Fernando|Zhang, Xian Feng|Solomon, Anna|Tong, Jeffrey|Read, Margaret|Fritz, Christian|Jimeno, Antonio|Pandey, Akhilesh|Hidalgo, Manue
PMID: 18852131
Journal: FEBS J. 2010 Sep;277(17):3552-63.
Title: Tumor suppressor p16 INK4a: Downregulation of galectin-3, an endogenous competitor of the pro-anoikis effector galectin-1, in a pancreatic carcinoma model.
Author: Sanchez-Ruderisch, Hugo|Fischer, Christian|Detjen, Katharina M|Welzel, Martina|Wimmel, Anja|Manning, Joachim C|Andre, Sabine|Gabius, Hans-Joachim
PMID: 20695889
Journal: Pancreatology. 2010;10(6):673-81.
Title: Pancreatic cancer: the role of pancreatic stellate cells in tumor progression.
Author: Duner, Siri|Lopatko Lindman, Jacob|Ansari, Daniel|Gundewar, Chinmay|Andersson, Roland
PMID: 21242706
Journal: Int J Cancer. 2011 Dec 15;129(12):2775-86.
Title: Transient gene silencing of galectin-3 suppresses pancreatic cancer cell migration and invasion through degradation of beta-catenin.
Author: Kobayashi, Tsutomu|Shimura, Tatsuo|Yajima, Toshiki|Kubo, Norio|Araki, Kenichiro|Tsutsumi, Soichi|Suzuki, Hideki|Kuwano, Hiroyuki|Raz, Avraham
PMID: 21448903
Journal: PLoS One. 2011;6(6):e20859.
Title: Comprehensive analysis of cellular galectin-3 reveals no consistent oncogenic function in pancreatic cancer cells.
Author: Hann, Alexander|Gruner, Anja|Chen, Ying|Gress, Thomas M|Buchholz, Malte
PMID: 21698183
Journal: Clin Exp Metastasis. 2011 Apr;28(4):367-76.
Title: Transient silencing of galectin-3 expression promotes both in vitro and in vivo drug-induced apoptosis of human pancreatic carcinoma cells.
Author: Kobayashi, Tsutomu|Shimura, Tatsuo|Yajima, Toshiki|Kubo, Norio|Araki, Kenichiro|Wada, Wataru|Tsutsumi, Soichi|Suzuki, Hideki|Kuwano, Hiroyuki|Raz, Avraham
PMID: 21331750
Journal: Oncogene. 2011 Jun 2;30(22):2514-25.
Title: Galectin-3 regulates MUC1 and EGFR cellular distribution and EGFR downstream pathways in pancreatic cancer cells.
Author: Merlin, J|Stechly, L|de Beauce, S|Monte, D|Leteurtre, E|van Seuningen, I|Huet, G|Pigny, P
PMID: 21258405
Journal: Clin Cancer Res. 2011 Jan 15;17(2):267-74.
Title: Novel INTeraction of MUC4 and galectin: potential pathobiological implications for metastasis in lethal pancreatic cancer.
Author: Senapati, Shantibhusan|Chaturvedi, Pallavi|Chaney, William G|Chakraborty, Subhankar|Gnanapragassam, Vinayaga S|Sasson, Aaron R|Batra, Surinder K
PMID: 21059814
Journal: PLoS One. 2012;7(8):e42699.
Title: Overexpressed galectin-3 in pancreatic cancer induces cell proliferation and invasion by binding Ras and activating Ras signaling.
Author: Song, Shumei|Ji, Baoan|Ramachandran, Vijaya|Wang, Huamin|Hafley, Margarete|Logsdon, Craig|Bresalier, Robert S
PMID: 22900040
Journal: Nucl Med Biol. 2013 Jul;40(5):606-17.
Title: 177Lu-labeled HPMA copolymers utilizing cathepsin B and S cleavable linkers: synthesis, characterization and preliminary in vivo investigation in a pancreatic cancer model.
Author: Ogbomo, Sunny M|Shi, Wen|Wagh, Nilesh K|Zhou, Zhengyuan|Brusnahan, Susan K|Garrison, Jered C
PMID: 23622691
Journal: J Proteomics. 2016 Mar 16;136:1-12.
Title: Secretome protein signature of human pancreatic cancer stem-like cells.
Author: Brandi, Jessica|Dalla Pozza, Elisa|Dando, Ilaria|Biondani, Giulia|Robotti, Elisa|Jenkins, Rosalind|Elliott, Victoria|Park, Kevin|Marengo, Emilio|Costello, Eithne|Scarpa, Aldo|Palmieri, Marta|Cecconi, Daniela
PMID: 26850699
Journal: Cell Death Dis. 2016 Aug 11;7(8):e2337.
Title: Cell surface galectin-3 defines a subset of chemoresistant gastrointestinal tumor-initiating cancer cells with heightened stem cell characteristics.
Author: Ilmer, Matthias|Mazurek, Nachman|Byrd, James C|Ramirez, Karen|Hafley, Margarete|Alt, Eckhard|Vykoukal, Jody|Bresalier, Robert S
PMID: 27512958
Journal: J Nanobiotechnology. 2016 Dec 19;14(1):81.
Title: Synthesis and functionalization of protease-activated nanoparticles with tissue plasminogen activator peptides as targeting moiety and diagnostic tool for pancreatic cancer.
Author: Dobiasch, Sophie|Szanyi, Szilard|Kjaev, Aleko|Werner, Jens|Strauss, Albert|Weis, Christian|Grenacher, Lars|Kapilov-Buchman, Katya|Israel, Liron-Limor|Lellouche, Jean-Paul|Locatelli, Erica|Franchini, Mauro Comes|Vandooren, Jennifer|Opdenakker, Ghislain|Fel
PMID: 27993133
Journal: J Mol Graph Model. 2017 Jan;71:211-217.
Title: Investigating carbohydrate based ligands for galectin-3 with docking and molecular dynamics studies.
Author: Walker, Alice R|Bonomi, Robin|Popov, Vadim|Gelovani, Juri G|Andres Cisneros, G
PMID: 27939933
Journal: Sci Rep. 2017 Mar 6;7:43927.
Title: Galectin-3 is a non-classic RNA binding protein that stabilizes the mucin MUC4 mRNA in the cytoplasm of cancer cells.
Author: Coppin, Lucie|Vincent, Audrey|Frenois, Frederic|Duchene, Belinda|Lahdaoui, Fatima|Stechly, Laurence|Renaud, Florence|Villenet, Celine|Van Seuningen, Isabelle|Leteurtre, Emmanuelle|Dion, Johann|Grandjean, Cyrille|Poirier, Francoise|Figeac, Martin|Delacour,
PMID: 28262838
Journal: Anticancer Res. 2017 Sep;37(9):4979-4986.
Title: Significance of Circulating Galectin-3 in Patients with Pancreatobiliary Cancer.
Author: Shimura, Tatsuo|Shibata, Masahiko|Gonda, Kenji|Kofunato, Yasuhide|Okada, Ryo|Ishigame, Teruhide|Kimura, Takashi|Kenjo, Akira|Kono, Koji|Marubashi, Shigeru
PMID: 28870921
Journal: Cancer Discov. 2017 Dec;7(12):1464-1479.
Title: Galectin-3, a Druggable Vulnerability for KRAS-Addicted Cancers.
Author: Seguin, Laetitia|Camargo, Maria F|Wettersten, Hiromi I|Kato, Shumei|Desgrosellier, Jay S|von Schalscha, Tami|Elliott, Kathryn C|Cosset, Erika|Lesperance, Jacqueline|Weis, Sara M|Cheresh, David A
PMID: 28893801
Journal: Gastroenterology. 2018 Apr;154(5):1524-1537.e6.
Title: Galectin-3 Mediates Tumor Cell-Stroma Interactions by Activating Pancreatic Stellate Cells to Produce Cytokines via Integrin Signaling.
Author: Zhao, Wei|Ajani, Jaffer A|Sushovan, Guha|Ochi, Nobuo|Hwang, Rosa|Hafley, Margarete|Johnson, Randy L|Bresalier, Robert S|Logsdon, Craig D|Zhang, Zhiqian|Song, Shumei
PMID: 29274868
Journal: Biomark Cancer. 2018 May 30;10:1179299X18776974.
Title: Clean Colorectum at Diagnostic Colonoscopy: Subsequent Detection of Extracolonic Malignancies by Plasma Protein Biomarkers?
Author: Wilhelmsen, Michael|Christensen, Ib J|Jorgensen, Lars N|Madsen, Mogens R|Vilandt, Jesper|Hillig, Thore|Klaerke, Michael|Nielsen, Knud T|Laurberg, Soren|Gawel, Susan|Yang, Xiaoping|Davis, Gerard|Heijboer, Anne Meike|Martens, Frans|Nielsen, Hans J
PMID: 29872358
Journal: Carbohydr Polym. 2019 Jan 15;204:111-123.
Title: HH1-1, a novel Galectin-3 inhibitor, exerts anti-pancreatic cancer activity by blocking Galectin-3/EGFR/AKT/FOXO3 signaling pathway.
Author: Yao, Yanli|Zhou, Lishuang|Liao, Wenfeng|Chen, Huanjun|Du, Zhenyun|Shao, Chenghao|Wang, Peipei|Ding, Kan
PMID: 30366522