Primary Site >> Pancreatic Cancer
Gene >> LGALS3
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Ref: Localization of galectin-3 in normal and diseased pancreatic tissue. PMID: 9520085 |
Ref: Biologic instability of pancreatic cancer xenografts in the nude mouse. PMID: 10836999 |
Ref: Comparative analysis of galectins in primary tumors and tumor metastasis in human pancreatic cancer. PMID: 11259457 |
Ref: Influences of the lysosomal associated membrane proteins (Lamp-1, Lamp-2) and Mac-2 binding protein (Mac-2-BP) on the prognosis of pancreatic carcinoma. PMID: 11815981 Ref: Characterization of gene expression profiles in intraductal papillary-mucinous tumors of the pancreas. PMID: 12000726 |
Ref: Gene expression profiling of microdissected pancreatic ductal carcinomas using high-density DNA microarrays. PMID: 15548371 |
Ref: Pancreatic stellate cells promote proliferation and invasiveness of human pancreatic cancer cells via galectin-3. PMID: 18395901 Ref: Antitumor activity and molecular effects of the novel heat shock protein 90 inhibitor, IPI-504, in pancreatic cancer. PMID: 18852131 |
Ref: Tumor suppressor p16 INK4a: Downregulation of galectin-3, an endogenous competitor of the pro-anoikis effector galectin-1, in a pancreatic carcinoma model. PMID: 20695889 Ref: Pancreatic cancer: the role of pancreatic stellate cells in tumor progression. PMID: 21242706 |
Ref: Novel INTeraction of MUC4 and galectin: potential pathobiological implications for metastasis in lethal pancreatic cancer. PMID: 21059814 Ref: Galectin-3 regulates MUC1 and EGFR cellular distribution and EGFR downstream pathways in pancreatic cancer cells. PMID: 21258405 Ref: Transient silencing of galectin-3 expression promotes both in vitro and in vivo drug-induced apoptosis of human pancreatic carcinoma cells. PMID: 21331750 Ref: Transient gene silencing of galectin-3 suppresses pancreatic cancer cell migration and invasion through degradation of beta-catenin. PMID: 21448903 Ref: Comprehensive analysis of cellular galectin-3 reveals no consistent oncogenic function in pancreatic cancer cells. PMID: 21698183 |
Ref: Overexpressed galectin-3 in pancreatic cancer induces cell proliferation and invasion by binding Ras and activating Ras signaling. PMID: 22900040 |
Ref: 177Lu-labeled HPMA copolymers utilizing cathepsin B and S cleavable linkers: synthesis, characterization and preliminary in vivo investigation in a pancreatic cancer model. PMID: 23622691 |
Ref: Secretome protein signature of human pancreatic cancer stem-like cells. PMID: 26850699 Ref: Cell surface galectin-3 defines a subset of chemoresistant gastrointestinal tumor-initiating cancer cells with heightened stem cell characteristics. PMID: 27512958 Ref: Synthesis and functionalization of protease-activated nanoparticles with tissue plasminogen activator peptides as targeting moiety and diagnostic tool for pancreatic cancer. PMID: 27993133 |
Ref: Investigating carbohydrate based ligands for galectin-3 with docking and molecular dynamics studies. PMID: 27939933 Ref: Galectin-3 is a non-classic RNA binding protein that stabilizes the mucin MUC4 mRNA in the cytoplasm of cancer cells. PMID: 28262838 Ref: Significance of Circulating Galectin-3 in Patients with Pancreatobiliary Cancer. PMID: 28870921 Ref: Galectin-3, a Druggable Vulnerability for KRAS-Addicted Cancers. PMID: 28893801 |
Ref: Galectin-3 Mediates Tumor Cell-Stroma Interactions by Activating Pancreatic Stellate Cells to Produce Cytokines via Integrin Signaling. PMID: 29274868 Ref: Clean Colorectum at Diagnostic Colonoscopy: Subsequent Detection of Extracolonic Malignancies by Plasma Protein Biomarkers? PMID: 29872358 |
Ref: HH1-1, a novel Galectin-3 inhibitor, exerts anti-pancreatic cancer activity by blocking Galectin-3/EGFR/AKT/FOXO3 signaling pathway. PMID: 30366522 |