Primary Site >> Liver Cancer

Gene >> LEPR

Journal: J Clin Pathol. 2006 Dec;59(12):1267-71.
Title: Potential prognostic value of leptin receptor in hepatocellular carcinoma.
Author: Wang, S-N|Chuang, S-C|Yeh, Y-T|Yang, S-F|Chai, C-Y|Chen, W-T|Kuo, K-K|Chen, J-S|Lee, K-T
PMID: 16565226
Journal: Cancer Prev Res (Phila). 2011 Jan;4(1):128-36.
Title: Acyclic retinoid inhibits diethylnitrosamine-induced liver tumorigenesis in obese and diabetic C57BLKS/J- +(db)/+Lepr(db) mice.
Author: Shimizu, Masahito|Sakai, Hiroyasu|Shirakami, Yohei|Iwasa, Junpei|Yasuda, Yoichi|Kubota, Masaya|Takai, Koji|Tsurumi, Hisashi|Tanaka, Takuji|Moriwaki, Hisataka
PMID: 21071580
Journal: Mol Diagn Ther. 2012 Dec;16(6):383-8.
Title: Role of leptin receptor (LEPR) gene polymorphisms and haplotypes in susceptibility to hepatocellular carcinoma in subjects with chronic hepatitis B virus infection.
Author: Li, Zhen|Yuan, Weitang|Ning, Shijie|Li, Jie|Zhai, Wenlong|Zhang, Shuijun
PMID: 23090836
Journal: World J Gastroenterol. 2013 Dec 21;19(47):8873-9.
Title: Target genes discovery through copy number alteration analysis in human hepatocellular carcinoma.
Author: Gu, De-Leung|Chen, Yen-Hsieh|Shih, Jou-Ho|Lin, Chi-Hung|Jou, Yuh-Shan|Chen, Chian-Feng
PMID: 24379610
Journal: Gastroenterology. 2014 Jan;146(1):222-32.e35.
Title: Leptin receptor somatic mutations are frequent in HCV-infected cirrhotic liver and associated with hepatocellular carcinoma.
Author: Ikeda, Atsuyuki|Shimizu, Takahiro|Matsumoto, Yuko|Fujii, Yosuke|Eso, Yuji|Inuzuka, Tadashi|Mizuguchi, Aya|Shimizu, Kazuharu|Hatano, Etsuro|Uemoto, Shinji|Chiba, Tsutomu|Marusawa, Hiroyuki
PMID: 24055508
Journal: Eur J Cancer Prev. 2016 May;25(3):206-15.
Title: Pentoxifylline prevents nonalcoholic steatohepatitis-related liver pre-neoplasms by inhibiting hepatic inflammation and lipogenesis.
Author: Shirakami, Yohei|Shimizu, Masahito|Kubota, Masaya|Ohno, Tomohiko|Kochi, Takahiro|Nakamura, Nobuhiko|Sumi, Takafumi|Tanaka, Takuji|Moriwaki, Hisataka|Seishima, Mitsuru
PMID: 26258810
Journal: Immunol Cell Biol. 2016 Apr;94(4):388-99.
Title: Hepatoma cell-derived leptin downregulates the immunosuppressive function of regulatory T-cells to enhance the anti-tumor activity of CD8+ T-cells.
Author: Wei, Renxiong|Hu, Yaoren|Dong, Feibo|Xu, Xiaozhen|Hu, Airong|Gao, Guosheng
PMID: 26639061
Journal: Eur J Nutr. 2017 Mar;56(2):535-544.
Title: Hepatic DNA hydroxymethylation is site-specifically altered by chronic alcohol consumption and aging.
Author: Tammen, Stephanie A|Park, Lara K|Dolnikowski, Gregory G|Ausman, Lynne M|Friso, Simonetta|Choi, Sang-Woon
PMID: 26578530
Journal: J Gastroenterol Hepatol. 2017 Mar;32(3):667-676.
Title: Concurrent fatty liver increases risk of hepatocellular carcinoma among patients with chronic hepatitis B.
Author: Chan, Anthony W H|Wong, Grace L H|Chan, Hoi-Yun|Tong, Joanna H M|Yu, Yau-Hei|Choi, Paul C L|Chan, Henry L Y|To, Ka-Fai|Wong, Vincent W S
PMID: 27547913
Journal: Oncotarget. 2017 Apr 6;8(35):58353-58363.
Title: Preventive effects of the sodium glucose cotransporter 2 inhibitor tofogliflozin on diethylnitrosamine-induced liver tumorigenesis in obese and diabetic mice.
Author: Obara, Koki|Shirakami, Yohei|Maruta, Akinori|Ideta, Takayasu|Miyazaki, Tsuneyuki|Kochi, Takahiro|Sakai, Hiroyasu|Tanaka, Takuji|Seishima, Mitsuru|Shimizu, Masahito
PMID: 28938561
Journal: Onco Targets Ther. 2018 Apr 11;11:2083-2089.
Title: Investigation of LEP and LEPR polymorphisms with the risk of hepatocellular carcinoma: a case-control study in Eastern Chinese Han population.
Author: Zhang, Sheng|Jiang, Jiakai|Chen, Zhan|Wang, Yafeng|Tang, Weifeng|Liu, Chao|Liu, Longgen|Chen, Yu
PMID: 29695916
Journal: Mol Metab. 2018 Sep 5. pii: S2212-8778(18)30678-1.
Title: Hepatic leptin receptor expression can partially compensate for IL-6Ralpha deficiency in DEN-induced hepatocellular carcinoma.
Author: Mittenbuhler, Melanie J|Sprenger, Hans-Georg|Gruber, Sabine|Wunderlich, Claudia M|Kern, Lara|Bruning, Jens C|Wunderlich, F Thomas
PMID: 30224299