Primary Site >> Colorectal Cancer
Gene >> LEPR
| 1. | |||||||||||
| Journal: | FASEB J. 2000 Nov;14(14):2329-38. | ||||||||||
| Title: | Leptin promotes invasiveness of kidney and colonic epithelial cells via phosphoinositide 3-kinase-, rho-, and rac-dependent signaling pathways. | ||||||||||
| Author: | Attoub, S|Noe, V|Pirola, L|Bruyneel, E|Chastre, E|Mareel, M|Wymann, M P|Gespach, C | ||||||||||
| PMID: | 11053255 | ||||||||||
| 2. | |||||||||||
| Journal: | Ann Oncol. 2007 Jun;18 Suppl 6:vi116-9. | ||||||||||
| Title: | Expression of the obesity hormone leptin and its receptor correlates with hypoxia-inducible factor-1 alpha in human colorectal cancer. | ||||||||||
| Author: | Koda, M|Sulkowska, M|Kanczuga-Koda, L|Cascio, S|Colucci, G|Russo, A|Surmacz, E|Sulkowski, S | ||||||||||
| PMID: | 17591803 | ||||||||||
| 3. | |||||||||||
| Journal: | Int J Cancer. 2008 Apr 1;122(7):1611-7. | ||||||||||
| Title: | Leptin and leptin receptor genotypes and colon cancer: gene-gene and gene-lifestyle interactions. | ||||||||||
| Author: | Slattery, Martha L|Wolff, Roger K|Herrick, Jennifer|Caan, Bette J|Potter, John D | ||||||||||
| PMID: | 18059035 | ||||||||||
| 4. | |||||||||||
| Journal: | Int J Colorectal Dis. 2009 Mar;24(3):289-94. | ||||||||||
| Title: | Obesity-related genes variability in Czech patients with sporadic colorectal cancer: preliminary results. | ||||||||||
| Author: | Vasku, Anna|Vokurka, Jiri|Bienertova-Vasku, Julie | ||||||||||
| PMID: | 18704460 | ||||||||||
| 5. | |||||||||||
| Journal: | Eur J Endocrinol. 2009 Jun;160(6):933-40. | ||||||||||
| Title: | Genetic variation in adipokine genes and risk of colorectal cancer. | ||||||||||
| Author: | Pechlivanis, Sonali|Bermejo, Justo Lorenzo|Pardini, Barbara|Naccarati, Alessio|Vodickova, Ludmila|Novotny, Jan|Hemminki, Kari|Vodicka, Pavel|Forsti, Asta | ||||||||||
| PMID: | 19273568 | ||||||||||
| 6. | |||||||||||
| Journal: | Carcinogenesis. 2009 Nov;30(11):1832-40. | ||||||||||
| Title: | Leptin receptor expression in Middle Eastern colorectal cancer and its potential clinical implication. | ||||||||||
| Author: | Uddin, Shahab|Bavi, Prashant P|Hussain, Azhar R|Alsbeih, Ghazi|Al-Sanea, Nasser|Abduljabbar, Alaa|Ashari, Luai H|Alhomoud, Samar|Al-Dayel, Fouad|Ahmed, Maqbool|Al-Kuraya, Khawla S | ||||||||||
| PMID: | 19520793 | ||||||||||
| 7. | |||||||||||
| Journal: | Endocr Relat Cancer. 2010 Aug 16;17(3):823-33. | ||||||||||
| Title: | Obesity hormone leptin induces growth and interferes with the cytotoxic effects of 5-fluorouracil in colorectal tumor stem cells. | ||||||||||
| Author: | Bartucci, Monica|Svensson, Susanne|Ricci-Vitiani, Lucia|Dattilo, Rosanna|Biffoni, Mauro|Signore, Michele|Ferla, Rita|De Maria, Ruggero|Surmacz, Eva | ||||||||||
| PMID: | 20603394 | ||||||||||
| 8. | |||||||||||
| Journal: | Horm Cancer. 2010 Dec;1(6):320-30. | ||||||||||
| Title: | Insulin glargine and NPH insulin increase to a similar degree epithelial cell proliferation and aberrant crypt foci formation in colons of diabetic mice. | ||||||||||
| Author: | Nagel, Jutta M|Staffa, Jurgen|Renner-Muller, Ingrid|Horst, David|Vogeser, Michael|Langkamp, Markus|Hoeflich, Andreas|Goke, Burkhard|Kolligs, Frank T|Mantzoros, Christos S | ||||||||||
| PMID: | 21761363 | ||||||||||
| 9. | |||||||||||
| Journal: | Cell Biochem Biophys. 2011 Jul;60(3):241-4. | ||||||||||
| Title: | Expression and biological significance of leptin, leptin receptor, VEGF, and CD34 in colorectal carcinoma. | ||||||||||
| Author: | Liu, Hui|Wan, Desen|Pan, Zhizhong|Cao, Lijing|Wu, Xiaojun|Lu, Zhenhai|Kang, Tai | ||||||||||
| PMID: | 21161731 | ||||||||||
| 10. | |||||||||||
| Journal: | Gut. 2011 Oct;60(10):1363-71. | ||||||||||
| Title: | Leptin acts as a growth factor for colorectal tumours at stages subsequent to tumour initiation in murine colon carcinogenesis. | ||||||||||
| Author: | Endo, Hiroki|Hosono, Kunihiro|Uchiyama, Takashi|Sakai, Eiji|Sugiyama, Michiko|Takahashi, Hirokazu|Nakajima, Noriko|Wada, Koichiro|Takeda, Kiyoshi|Nakagama, Hitoshi|Nakajima, Atsushi | ||||||||||
| PMID: | 21406387 | ||||||||||
| 11. | |||||||||||
| Journal: | Gastroenterol Hepatol Bed Bench. 2011 Fall;4(4):192-8. | ||||||||||
| Title: | Association of leptin receptor gene Gln223Arg polymorphism with susceptibility to colorectal cancer. | ||||||||||
| Author: | Karimi, Khatoon|Arkani, Maral|Safaei, Akram|Pourhoseingholi, Mohamad Amin|Mohebbi, Seyed Reza|Fatemi, Seyed Reza|Vafaei, Mohammad | ||||||||||
| PMID: | 24834182 | ||||||||||
| 12. | |||||||||||
| Journal: | Int J Obes (Lond). 2012 Feb;36(2):273-80. | ||||||||||
| Title: | Effects of diet-induced obesity on colitis-associated colon tumor formation in A/J mice. | ||||||||||
| Author: | Park, S-Y|Kim, J-S|Seo, Y-R|Sung, M-K | ||||||||||
| PMID: | 21544082 | ||||||||||
| 13. | |||||||||||
| Journal: | J Biosci. 2012 Mar;37(1):91-101. | ||||||||||
| Title: | Leptin regulates proliferation and apoptosis of colorectal carcinoma through PI3K/Akt/mTOR signalling pathway. | ||||||||||
| Author: | Wang, Di|Chen, Jian|Chen, Hui|Duan, Zhi|Xu, Qimei|Wei, Meiyan|Wang, Lianghua|Zhong, Meizuo | ||||||||||
| PMID: | 22357207 | ||||||||||
| 14. | |||||||||||
| Journal: | Braz J Med Biol Res. 2013 Mar;46(3):306-10. Epub 2013 Mar 19. | ||||||||||
| Title: | Leptin receptor (Ob-R) mRNA expression and serum leptin concentration in patients with colorectal and metastatic colorectal cancer. | ||||||||||
| Author: | Erkasap, N|Ozkurt, M|Erkasap, S|Yasar, F|Uzuner, K|Ihtiyar, E|Uslu, S|Kara, M|Bolluk, O | ||||||||||
| PMID: | 23558862 | ||||||||||
| 15. | |||||||||||
| Journal: | Iran J Cancer Prev. 2013 Fall;6(4):179-85. | ||||||||||
| Title: | The Association between Polymorphismsin Insulin and Obesity Related Genesand Risk of Colorectal Cancer. | ||||||||||
| Author: | Rezaei-Tavirani, Mostafa|Safaei, Akram|Zali, Mohammad Reza | ||||||||||
| PMID: | 25250132 | ||||||||||
| 16. | |||||||||||
| Journal: | Cancer Causes Control. 2013 Dec;24(12):2077-87. | ||||||||||
| Title: | Plasma C-reactive protein, genetic risk score, and risk of common cancers in the Atherosclerosis Risk in Communities study. | ||||||||||
| Author: | Prizment, Anna E|Folsom, Aaron R|Dreyfus, Jill|Anderson, Kristin E|Visvanathan, Kala|Joshu, Corinne E|Platz, Elizabeth A|Pankow, James S | ||||||||||
| PMID: | 24036889 | ||||||||||
| 17. | |||||||||||
| Journal: | PLoS One. 2013 Apr 8;8(4):e60777. | ||||||||||
| Title: | The leptin gene family and colorectal cancer: interaction with smoking behavior and family history of cancer. | ||||||||||
| Author: | Liu, Li|Zhong, Rong|Wei, Sheng|Xiang, Hao|Chen, Jigui|Xie, Duoshuang|Yin, Jieyun|Zou, Li|Sun, Jingwen|Chen, Wei|Miao, Xiaoping|Nie, Shaofa | ||||||||||
| PMID: | 23593308 | ||||||||||
| 18. | |||||||||||
| Journal: | Peptides. 2013 Jun;44:127-34. | ||||||||||
| Title: | Designer peptide antagonist of the leptin receptor with peripheral antineoplastic activity. | ||||||||||
| Author: | Beccari, Serena|Kovalszky, Ilona|Wade, John D|Otvos, Laszlo Jr|Surmacz, Eva | ||||||||||
| PMID: | 23567149 | ||||||||||
| 19. | |||||||||||
| Journal: | Expert Opin Ther Targets. 2014 Aug;18(8):961-71. | ||||||||||
| Title: | Oncogenic role and therapeutic target of leptin signaling in colorectal cancer. | ||||||||||
| Author: | Zhou, Weiqiang|Tian, Yuwang|Gong, Hangjun|Guo, Shanchun|Luo, Chengyu | ||||||||||
| PMID: | 24946986 | ||||||||||
| 20. | |||||||||||
| Journal: | Carcinogenesis. 2014 Sep;35(9):2134-41. | ||||||||||
| Title: | Conditional knockout of the leptin receptor in the colonic epithelium revealed the local effects of leptin receptor signaling in the progression of colonic tumors in mice. | ||||||||||
| Author: | Higurashi, Takuma|Endo, Hiroki|Uchiyama, Takashi|Uchiyama, Shiori|Yamada, Eiji|Ohkubo, Hidenori|Sakai, Eiji|Takahashi, Hirokazu|Maeda, Shin|Wada, Koichiro|Natsumeda, Yutaka|Hippo, Yoshitaka|Nakajima, Atsushi|Nakagama, Hitoshi | ||||||||||
| PMID: | 24958593 | ||||||||||
| 21. | |||||||||||
| Journal: | Oncol Lett. 2014 Jul;8(1):223-229. | ||||||||||
| Title: | Preventive effects of the angiotensin-converting enzyme inhibitor, captopril, on the development of azoxymethane-induced colonic preneoplastic lesions in diabetic and hypertensive rats. | ||||||||||
| Author: | Kochi, Takahiro|Shimizu, Masahito|Ohno, Tomohiko|Baba, Atsushi|Sumi, Takafumi|Kubota, Masaya|Shirakami, Yohei|Tsurumi, Hisashi|Tanaka, Takuji|Moriwaki, Hisataka | ||||||||||
| PMID: | 24959250 | ||||||||||
| 22. | |||||||||||
| Journal: | Mol Nutr Food Res. 2014 Dec;58(12):2274-85. | ||||||||||
| Title: | Carnosic acid suppresses colon tumor formation in association with antiadipogenic activity. | ||||||||||
| Author: | Kim, Yun-Ji|Kim, Jong-Sang|Seo, Young Rok|Park, Jung Han Yoon|Choi, Myung-Sook|Sung, Mi-Kyung | ||||||||||
| PMID: | 25204550 | ||||||||||
| 23. | |||||||||||
| Journal: | J BUON. 2014 Jul-Sep;19(3):855-62. | ||||||||||
| Title: | Lack of association between LEPR Q223R polymorphisms and cancer susceptibility: evidence from a meta-analysis. | ||||||||||
| Author: | Liu, Pengcheng|Shi, Hui|Liu, Run|Yang, Yunji|Yang, Yong|Huang, Changjia|Shu, Hexi|Gong, Jinpeng|Cai, Ming | ||||||||||
| PMID: | 25261679 | ||||||||||
| 24. | |||||||||||
| Journal: | J BUON. 2015 Jan-Feb;20(1):100-8. | ||||||||||
| Title: | Involvement of leptin receptors expression in proliferation and neoangiogenesis in colorectal carcinoma. | ||||||||||
| Author: | Milosevic, Velimir S|Vukmirovic, Filip C|Krstic, Miljan S|Zindovic, Miljan M|Lj Stojanovic, Dragos|Jancic, Snezana A | ||||||||||
| PMID: | 25778303 | ||||||||||
| 25. | |||||||||||
| Journal: | J Cancer. 2016 Aug 12;7(13):1780-1790. | ||||||||||
| Title: | Diet- and Genetically-induced Obesity Produces Alterations in the Microbiome, Inflammation and Wnt Pathway in the Intestine of Apc(+/1638N) Mice: Comparisons and Contrasts. | ||||||||||
| Author: | Liu, Wei|Crott, Jimmy W|Lyu, Lin|Pfalzer, Anna C|Li, Jinchao|Choi, Sang-Woon|Yang, Yingke|Mason, Joel B|Liu, Zhenhua | ||||||||||
| PMID: | 27698916 | ||||||||||
| 26. | |||||||||||
| Journal: | Iran J Cancer Prev. 2016 Jun 13;9(3):e7013. | ||||||||||
| Title: | Genetic Variations in Leptin and Leptin Receptor and Susceptibility to Colorectal Cancer and Obesity. | ||||||||||
| Author: | Mahmoudi, Touraj|Farahani, Hamid|Nobakht, Hossein|Dabiri, Reza|Zali, Mohammad Reza | ||||||||||
| PMID: | 27703650 | ||||||||||
| 27. | |||||||||||
| Journal: | J Surg Oncol. 2018 Jun;117(8):1833-1840. | ||||||||||
| Title: | Upregulation of the adipokine genes ADIPOR1 and SPP1 is related to poor survival outcomes in colorectal cancer. | ||||||||||
| Author: | Choe, Eun K|Yi, Jin W|Chai, Young J|Park, Kyu J | ||||||||||
| PMID: | 29761507 | ||||||||||