Primary Site >> Colorectal Cancer

Gene >> LEF1

Journal: Oncogene. 1997 Dec 4;15(23):2833-9.
Title: Induction of a beta-catenin-LEF-1 complex by wnt-1 and transforming mutants of beta-catenin.
Author: Porfiri, E|Rubinfeld, B|Albert, I|Hovanes, K|Waterman, M|Polakis, P
PMID: 9419974
Journal: J Cell Biol. 1998 Jun 15;141(6):1433-48.
Title: Differential nuclear translocation and transactivation potential of beta-catenin and plakoglobin.
Author: Simcha, I|Shtutman, M|Salomon, D|Zhurinsky, J|Sadot, E|Geiger, B|Ben-Ze'ev, A
PMID: 9628899
Journal: Cancer Res. 1998 Aug 15;58(16):3526-8.
Title: Beta-catenin mutation in carcinoma of the uterine endometrium.
Author: Fukuchi, T|Sakamoto, M|Tsuda, H|Maruyama, K|Nozawa, S|Hirohashi, S
PMID: 9721853
Journal: Nat Genet. 1999 Apr;21(4):410-3.
Title: A common human skin tumour is caused by activating mutations in beta-catenin.
Author: Chan, E F|Gat, U|McNiff, J M|Fuchs, E
PMID: 10192393
Journal: Cancer Res. 2000 Jul 1;60(13):3379-83.
Title: Differential formation of beta-catenin/lymphoid enhancer factor-1 DNA binding complex induced by nitric oxide in mouse colonic epithelial cells differing in adenomatous polyposis coli (Apc) genotype.
Author: Mei, J M|Hord, N G|Winterstein, D F|Donald, S P|Phang, J M
PMID: 10910042
Journal: FASEB J. 2000 Jun;14(9):1188-201.
Title: Expression of prostaglandin endoperoxide H synthase-2 induced by nitric oxide in conditionally immortalized murine colonic epithelial cells.
Author: Mei, J M|Hord, N G|Winterstein, D F|Donald, S P|Phang, J M
PMID: 10834941
Journal: Mol Cell Biol. 2001 Feb;21(4):1370-83.
Title: The PEA3 subfamily of Ets transcription factors synergizes with beta-catenin-LEF-1 to activate matrilysin transcription in intestinal tumors.
Author: Crawford, H C|Fingleton, B|Gustavson, M D|Kurpios, N|Wagenaar, R A|Hassell, J A|Matrisian, L M
PMID: 11158322
Journal: Nat Genet. 2001 May;28(1):53-7.
Title: Beta-catenin-sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer.
Author: Hovanes, K|Li, T W|Munguia, J E|Truong, T|Milovanovic, T|Lawrence Marsh, J|Holcombe, R F|Waterman, M L
PMID: 11326276
Journal: Cell Biol Int. 2001;25(5):421-7.
Title: Tyrosine phosphorylation translocates beta-catenin from cell-->cell interface to the cytoplasm, but does not significantly enhance the LEF-1-dependent transactivating function.
Author: Kim, K|Lee, K Y
PMID: 11401329
Journal: Curr Opin Gastroenterol. 2002 Jan;18(1):53-9.
Title: Expression of lymphoid enhancer factor/T-cell factor proteins in colon cancer.
Author: Waterman, Marian L
PMID: 17031231
Journal: Genes Dev. 2002 Aug 15;16(16):2058-72.
Title: Nr-CAM is a target gene of the beta-catenin/LEF-1 pathway in melanoma and colon cancer and its expression enhances motility and confers tumorigenesis.
Author: Conacci-Sorrell, Maralice E|Ben-Yedidia, Tamar|Shtutman, Michael|Feinstein, Elena|Einat, Paz|Ben-Ze'ev, Avri
PMID: 12183361
Journal: Chem Biol. 2002 Jul;9(7):821-7.
Title: Genomic effects of polyamide/DNA interactions on mRNA expression.
Author: Supekova, Lubica|Pezacki, John Paul|Su, Andrew I|Loweth, Colin J|Riedl, Rainer|Geierstanger, Bernhard|Schultz, Peter G|Wemmer, David E
PMID: 12144926
Journal: J Cell Sci. 2002 Jul 1;115(Pt 13):2771-80.
Title: Regulation of S33/S37 phosphorylated beta-catenin in normal and transformed cells.
Author: Sadot, Einat|Conacci-Sorrell, Maralice|Zhurinsky, Jacob|Shnizer, Dalia|Lando, Zeev|Zharhary, Dorit|Kam, Zvi|Ben-Ze'ev, Avri|Geiger, Benjamin
PMID: 12077367
Journal: J Biol Chem. 2002 Jul 5;277(27):24258-64. Epub 2002 May 1.
Title: Lymphoid enhancer factor-1 blocks adenomatous polyposis coli-mediated nuclear export and degradation of beta-catenin. Regulation by histone deacetylase 1.
Author: Henderson, Beric R|Galea, Melanie|Schuechner, Stefan|Leung, Louie
PMID: 11986304
Journal: J Biol Chem. 2003 May 2;278(18):16169-75. Epub 2003 Feb 11.
Title: A new beta-catenin-dependent activation domain in T cell factor.
Author: Atcha, Fawzia A|Munguia, Jesus E|Li, Tony W H|Hovanes, Karine|Waterman, Marian L
PMID: 12582159
Journal: Dev Biol. 2003 Jul 15;259(2):258-71.
Title: Wnt signaling during development of the gastrointestinal tract.
Author: Theodosiou, Nicole A|Tabin, Clifford J
PMID: 12871700
Journal: Int J Immunopathol Pharmacol. 2003 May-Aug;16(2 Suppl):59-67.
Title: Transcriptional regulation of cyclo-oxygenase expression: three pillars of control.
Author: Ramsay, R G|Ciznadija, D|Vanevski, M|Mantamadiotis, T
PMID: 14552705
Journal: Mol Cancer. 2003 Dec 15;2:42.
Title: Regulation of COX-2 transcription in a colon cancer cell line by Pontin52/TIP49a.
Author: Carlson, Mary L|Wilson, Ellen T|Prescott, Stephen M
PMID: 14675489
Journal: Cancer Metastasis Rev. 2004 Jan-Jun;23(1-2):41-52.
Title: Lymphoid enhancer factor/T cell factor expression in colorectal cancer.
Author: Waterman, Marian L
PMID: 15000148
Journal: Nucleic Acids Res. 2004 May 11;32(8):2660-74.
Title: Pharmacological and genetic modulation of Wnt-targeted Cre-Lox-mediated gene expression in colorectal cancer cells.
Author: Bordonaro, Michael|Lazarova, Darina L|Sartorelli, Alan C
PMID: 15141037
Journal: BMC Cancer. 2004 Jul 9;4:31.
Title: Is the gene encoding Chibby implicated as a tumour suppressor in colorectal cancer ?
Author: Gad, Sophie|Teboul, David|Lievre, Astrid|Goasguen, Nicolas|Berger, Anne|Beaune, Philippe|Laurent-Puig, Pierre
PMID: 15245581
Journal: Tumour Biol. 2004 Jul-Aug;25(4):157-60.
Title: Tissue microarray analysis of cyclin D1 gene amplification and gain in colorectal carcinomas.
Author: Toncheva, D|Petrova, D|Tzenova, V|Dimova, I|Yankova, R|Yordanov, V|Damjanov, D|Todorov, T|Zaharieva, B
PMID: 15557752
Journal: Br J Cancer. 2005 Apr 25;92(8):1581-7.
Title: Gastrin stabilises beta-catenin protein in mouse colorectal cancer cells.
Author: Song, D H|Kaufman, J C|Borodyansky, L|Albanese, C|Pestell, R G|Wolfe, M Michael
PMID: 15798764
Journal: Oncogene. 2005 Mar 31;24(14):2410-20.
Title: Constitutive activation of the Wnt/beta-catenin signalling pathway in acute myeloid leukaemia.
Author: Simon, Maria|Grandage, Victoria L|Linch, David C|Khwaja, Asim
PMID: 15735743
Journal: Mol Cell Biol. 2006 Jul;26(14):5284-99.
Title: Wnt activation and alternative promoter repression of LEF1 in colon cancer.
Author: Li, Tony W-H|Ting, Ju-Hui T|Yokoyama, Noriko N|Bernstein, Alla|van de Wetering, Marc|Waterman, Marian L
PMID: 16809766
Journal: Cancer Res. 2007 Sep 15;67(18):8690-8.
Title: Mastermind-like 1 Is a specific coactivator of beta-catenin transcription activation and is essential for colon carcinoma cell survival.
Author: Alves-Guerra, Marie-Clotilde|Ronchini, Chiara|Capobianco, Anthony J
PMID: 17875709
Journal: Genes Cells. 2007 Dec;12(12):1339-45.
Title: Putative tumor suppressor EDD interacts with and up-regulates APC.
Author: Ohshima, Ryuichi|Ohta, Tomohiko|Wu, Wenwen|Koike, Ayaka|Iwatani, Tsuguo|Henderson, Michelle|Watts, Colin K W|Otsubo, Takehito
PMID: 18076571
Journal: Mol Nutr Food Res. 2008 Jun;52 Suppl 1:S52-61.
Title: Low concentrations of resveratrol inhibit Wnt signal throughput in colon-derived cells: implications for colon cancer prevention.
Author: Hope, Christopher|Planutis, Kestutis|Planutiene, Marina|Moyer, Mary P|Johal, Karanjodh S|Woo, Jaesung|Santoso, Calista|Hanson, Joseph A|Holcombe, Randall F
PMID: 18504708
Journal: Eur J Haematol. 2009 Mar;82(3):165-75.
Title: Small molecule inhibitors of WNT signaling effectively induce apoptosis in acute myeloid leukemia cells.
Author: Minke, Katharina Salome|Staib, Peter|Puetter, Adriane|Gehrke, Iris|Gandhirajan, Rajesh Kumar|Schlosser, Axel|Schmitt, Esther Katharina|Hallek, Michael|Kreuzer, Karl-Anton
PMID: 19067737
Journal: Nat Cell Biol. 2009 Feb;11(2):162-71.
Title: Nuclear signalling by tumour-associated antigen EpCAM.
Author: Maetzel, Dorothea|Denzel, Sabine|Mack, Brigitte|Canis, Martin|Went, Philip|Benk, Michael|Kieu, Cuong|Papior, Peer|Baeuerle, Patrick A|Munz, Markus|Gires, Olivier
PMID: 19136966
Journal: BMC Cancer. 2009 May 21;9:159.
Title: Groucho binds two conserved regions of LEF-1 for HDAC-dependent repression.
Author: Arce, Laura|Pate, Kira T|Waterman, Marian L
PMID: 19460168
Journal: Biochem J. 2009 Aug 27;422(3):493-501.
Title: The transcriptional activity of Pygopus is enhanced by its interaction with cAMP-response-element-binding protein (CREB)-binding protein.
Author: Andrews, Phillip G P|He, Zhijian|Popadiuk, Cathy|Kao, Kenneth R
PMID: 19555349
Journal: Nucleic Acids Res. 2010 Oct;38(19):6375-88.
Title: A role for YY1 in repression of dominant negative LEF-1 expression in colon cancer.
Author: Yokoyama, Noriko N|Pate, Kira T|Sprowl, Stephanie|Waterman, Marian L
PMID: 20525792
Journal: J Transl Med. 2010 Nov 22;8:123.
Title: LEF-1 and TCF4 expression correlate inversely with survival in colorectal cancer.
Author: Kriegl, Lydia|Horst, David|Reiche, Jana A|Engel, Jutta|Kirchner, Thomas|Jung, Andreas
PMID: 21092222
Journal: Cancer Res. 2010 Nov 15;70(22):9298-308.
Title: WNT11 expression is induced by estrogen-related receptor alpha and beta-catenin and acts in an autocrine manner to increase cancer cell migration.
Author: Dwyer, Mary A|Joseph, James D|Wade, Hilary E|Eaton, Matthew L|Kunder, Rebecca S|Kazmin, Dmitri|Chang, Ching-yi|McDonnell, Donald P
PMID: 20870744
Journal: Cancer Biother Radiopharm. 2010 Feb;25(1):105-16.
Title: Selective suicide gene therapy of colon cancer cell lines exploiting fibroblast growth factor 18 promoter.
Author: Teimoori-Toolabi, Ladan|Azadmanesh, Kayhan|Zeinali, Sirous
PMID: 20187803
Journal: J Biol Chem. 2011 Apr 1;286(13):10950-9.
Title: Lef1DeltaN binds beta-catenin and increases osteoblast activity and trabecular bone mass.
Author: Hoeppner, Luke H|Secreto, Frank J|Razidlo, David F|Whitney, Tiffany J|Westendorf, Jennifer J
PMID: 21270130
Journal: PLoS One. 2011 Feb 24;6(2):e16636.
Title: Comparative profiling of primary colorectal carcinomas and liver metastases identifies LEF1 as a prognostic biomarker.
Author: Lin, Albert Y|Chua, Mei-Sze|Choi, Yoon-La|Yeh, William|Kim, Young H|Azzi, Raymond|Adams, Gregg A|Sainani, Kristin|van de Rijn, Matt|So, Samuel K|Pollack, Jonathan R
PMID: 21383983
Journal: PLoS One. 2011 Mar 18;6(3):e17957.
Title: The Notch-2 gene is regulated by Wnt signaling in cultured colorectal cancer cells.
Author: Ungerback, Jonas|Elander, Nils|Grunberg, John|Sigvardsson, Mikael|Soderkvist, Peter
PMID: 21437251
Journal: Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2011 Mar;36(3):235-42.
Title: [Role of NGX6 in Wnt/beta-catenin signaling pathway in colon cancer].
Author: Liu, Fen|Sheng, Shourong|Wang, Xiaoyan|Peng, Ya|Guo, Qin|Xiao, Zhiming|Liu, Jie
PMID: 21464545
Journal: Mol Cell Proteomics. 2011 Aug;10(8):M111.010462.
Title: Genome-wide characterization of miR-34a induced changes in protein and mRNA expression by a combined pulsed SILAC and microarray analysis.
Author: Kaller, Markus|Liffers, Sven-Thorsten|Oeljeklaus, Silke|Kuhlmann, Katja|Roh, Simone|Hoffmann, Reinhard|Warscheid, Bettina|Hermeking, Heiko
PMID: 21566225
Journal: Hum Mol Genet. 2011 Dec 1;20(23):4655-65.
Title: KDM6B/JMJD3 histone demethylase is induced by vitamin D and modulates its effects in colon cancer cells.
Author: Pereira, Fabio|Barbachano, Antonio|Silva, Javier|Bonilla, Felix|Campbell, Moray J|Munoz, Alberto|Larriba, Maria Jesus
PMID: 21890490
Journal: PLoS One. 2011;6(10):e26143.
Title: Human FasL gene is a target of beta-catenin/T-cell factor pathway and complex FasL haplotypes alter promoter functions.
Author: Wu, Jianming|Richards, Maureen H|Huang, Jinhai|Al-Harthi, Lena|Xu, Xiulong|Lin, Rui|Xie, Fenglong|Gibson, Andrew W|Edberg, Jeffrey C|Kimberly, Robert P
PMID: 22022540
Journal: Cell Calcium. 2012 Jun;51(6):470-7.
Title: S100A6 is transcriptionally regulated by beta-catenin and interacts with a novel target, lamin A/C, in colorectal cancer cells.
Author: Kilanczyk, Ewa|Graczyk, Agnieszka|Ostrowska, Halina|Kasacka, Irena|Lesniak, Wieslawa|Filipek, Anna
PMID: 22560296
Journal: Med Mol Morphol. 2013 Mar;46(1):14-9.
Title: Identification of DNA-dependent protein kinase catalytic subunit as a novel interaction partner of lymphocyte enhancer factor 1.
Author: Shimomura, Atsushi|Takasaki, Akihiko|Nomura, Ryuji|Hayashi, Nobuhiro|Senda, Takao
PMID: 23325550
Journal: Proc Natl Acad Sci U S A. 2013 Jan 8;110(2):630-5.
Title: Fucosyltransferase 8 as a functional regulator of nonsmall cell lung cancer.
Author: Chen, Chien-Yu|Jan, Yi-Hua|Juan, Yi-Hsiu|Yang, Chih-Jen|Huang, Ming-Shyan|Yu, Chong-Jen|Yang, Pan-Chyr|Hsiao, Michael|Hsu, Tsui-Ling|Wong, Chi-Huey
PMID: 23267084
Journal: Dis Markers. 2013;35(5):395-405.
Title: Increased LEF1 expression and decreased Notch2 expression are strong predictors of poor outcomes in colorectal cancer patients.
Author: Wang, Wen-Juan|Yao, Yu|Jiang, Li-Li|Hu, Ting-Hua|Ma, Jie-Qun|Ruan, Zhi-Ping|Tian, Tao|Guo, Hui|Wang, Shu-Hong|Nan, Ke-Jun
PMID: 24223455
Journal: Dig Dis Sci. 2013 Sep;58(9):2507-17.
Title: Inhibitory effect of a standardized pomegranate fruit extract on Wnt signalling in 1, 2-dimethylhydrazine induced rat colon carcinogenesis.
Author: Sadik, Nermin Abdel Hamid|Shaker, Olfat Gamil
PMID: 23722564
Journal: PLoS One. 2013 Oct 2;8(10):e76596.
Title: Knockdown of lymphoid enhancer factor 1 inhibits colon cancer progression in vitro and in vivo.
Author: Wang, Wen-Juan|Yao, Yu|Jiang, Li-Li|Hu, Ting-Hua|Ma, Jie-Qun|Liao, Zi-Jun|Yao, Jun-Tao|Li, Dong-Fan|Wang, Shu-Hong|Nan, Ke-Jun
PMID: 24098538
Journal: Appl Immunohistochem Mol Morphol. 2014 Nov-Dec;22(10):728-34.
Title: LEF-1 is frequently expressed in colorectal carcinoma and not in other gastrointestinal tract adenocarcinomas: an immunohistochemical survey of 602 gastrointestinal tract neoplasms.
Author: Kermanshahi, Taher R|Jayachandran, Priya|Chang, Daniel T|Pai, Reet
PMID: 25394300
Journal: Mol Cancer Ther. 2014 Jul;13(7):1942-51.
Title: MicroRNA-26b represses colon cancer cell proliferation by inhibiting lymphoid enhancer factor 1 expression.
Author: Zhang, Zichao|Kim, KyoungHyun|Li, Xiao|Moreno, Myriam|Sharp, Thad|Goodheart, Michael J|Safe, Stephen|Dupuy, Adam J|Amendt, Brad A
PMID: 24785257
Journal: J Mol Cell Biol. 2014 Jun;6(3):231-9.
Title: Thymine DNA glycosylase promotes transactivation of beta-catenin/TCFs by cooperating with CBP.
Author: Jia, Yingying|Nie, Fen|Du, Aiying|Chen, Zhangcheng|Qin, Yuanbo|Huang, Tao|Song, Xiaomin|Li, Lin
PMID: 24748645
Journal: BMC Cancer. 2014 Mar 14;14:182.
Title: Dissecting the signaling pathways associated with the oncogenic activity of MLK3 P252H mutation.
Author: Velho, Sergia|Pinto, Ana|Licastro, Danilo|Oliveira, Maria Jose|Sousa, Filipa|Stupka, Elia|Seruca, Raquel
PMID: 24628919
Journal: Nat Neurosci. 2014 Apr;17(4):506-12.
Title: Parallel states of pathological Wnt signaling in neonatal brain injury and colon cancer.
Author: Fancy, Stephen P J|Harrington, Emily P|Baranzini, Sergio E|Silbereis, John C|Shiow, Lawrence R|Yuen, Tracy J|Huang, Eric J|Lomvardas, Stavros|Rowitch, David H
PMID: 24609463
Journal: Cell Death Dis. 2014 Feb 27;5:e1085.
Title: The LEF1/CYLD axis and cIAPs regulate RIP1 deubiquitination and trigger apoptosis in selenite-treated colorectal cancer cells.
Author: Wu, P|Shi, K J|An, J J|Ci, Y L|Li, F|Hui, K Y|Yang, Y|Xu, C M
PMID: 24577083
Journal: Cancer Res. 2014 Mar 1;74(5):1495-505.
Title: LEF1 and B9L shield beta-catenin from inactivation by Axin, desensitizing colorectal cancer cells to tankyrase inhibitors.
Author: de la Roche, Marc|Ibrahim, Ashraf E K|Mieszczanek, Juliusz|Bienz, Mariann
PMID: 24419084
Journal: Ann Surg Oncol. 2014 Dec;21 Suppl 4:S515-21.
Title: Allelic imbalance at an 8q24 oncogenic SNP is involved in activating MYC in human colorectal cancer.
Author: Sugimachi, Keishi|Niida, Atsushi|Yamamoto, Ken|Shimamura, Teppei|Imoto, Seiya|Iinuma, Hisae|Shinden, Yoshiaki|Eguchi, Hidetoshi|Sudo, Tomoya|Watanabe, Masahiko|Tanaka, Junichi|Kudo, Shinei|Hase, Kazuo|Kusunoki, Masato|Yamada, Kazutaka|Shimada, Yasuhiro|Su
PMID: 24390711
Journal: Oncogene. 2015 May 14;34(20):2575-85.
Title: DACT2 is a functional tumor suppressor through inhibiting Wnt/beta-catenin pathway and associated with poor survival in colon cancer.
Author: Wang, S|Dong, Y|Zhang, Y|Wang, X|Xu, L|Yang, S|Li, X|Dong, H|Xu, L|Su, L|Ng, S S M|Chang, Z|Sung, J J|Zhang, X|Yu, J
PMID: 25023701
Journal: Oncogene. 2015 Sep 17;34(38):4914-27.
Title: Oncogenic KRAS signalling promotes the Wnt/beta-catenin pathway through LRP6 in colorectal cancer.
Author: Lemieux, E|Cagnol, S|Beaudry, K|Carrier, J|Rivard, N
PMID: 25500543
Journal: J Biol Regul Homeost Agents. 2015 Jul-Sep;29(3 Suppl 1):89-96.
Title: CDH1 POLYMORPHISMS AND LOW EXPRESSION OF E-CADHERIN AND beta-CATENIN IN COLORECTAL CANCER PATIENTS.
Author: Martinelli, M|Palmieri, A|Rodia, M T|Cura, F|Scapoli, L|Ugolini, G|Montroni, I|De Sanctis, P|Solmi, R
PMID: 26511186
Journal: PLoS One. 2015 Nov 6;10(11):e0141753.
Title: The Anti-Tumor Activity of Succinyl Macrolactin A Is Mediated through the beta-Catenin Destruction Complex via the Suppression of Tankyrase and PI3K/Akt.
Author: Regmi, Sushil C|Park, Su Young|Kim, Seung Joo|Banskota, Suhrid|Shah, Sajita|Kim, Dong-Hee|Kim, Jung-Ae
PMID: 26544726
Journal: Cancer Metab. 2016 Oct 3;4:20.
Title: Lactate/pyruvate transporter MCT-1 is a direct Wnt target that confers sensitivity to 3-bromopyruvate in colon cancer.
Author: Sprowl-Tanio, Stephanie|Habowski, Amber N|Pate, Kira T|McQuade, Miriam M|Wang, Kehui|Edwards, Robert A|Grun, Felix|Lyou, Yung|Waterman, Marian L
PMID: 27729975
Journal: Biochim Biophys Acta. 2016 Nov;1859(11):1353-1367.
Title: Enhancer decommissioning by Snail1-induced competitive displacement of TCF7L2 and down-regulation of transcriptional activators results in EPHB2 silencing.
Author: Schnappauf, Oskar|Beyes, Sven|Dertmann, Annika|Freihen, Vivien|Frey, Patrick|Jagle, Sabine|Rose, Katja|Michoel, Tom|Grosschedl, Rudolf|Hecht, Andreas
PMID: 27504909
Journal: Cell Discov. 2016 Jan 5;2:15039.
Title: A novel role for the tumour suppressor Nitrilase1 modulating the Wnt/beta-catenin signalling pathway.
Author: Mittag, Sonnhild|Valenta, Tomas|Weiske, Jorg|Bloch, Laura|Klingel, Susanne|Gradl, Dietmar|Wetzel, Franziska|Chen, Yuan|Petersen, Iver|Basler, Konrad|Huber, Otmar
PMID: 27462437
Journal: J Surg Res. 2016 Jun 1;203(1):193-205.
Title: The anthelmintic niclosamide inhibits colorectal cancer cell lines via modulation of the canonical and noncanonical Wnt signaling pathway.
Author: Monin, Malte B|Krause, Petra|Stelling, Robin|Bocuk, Derya|Niebert, Sabine|Klemm, Florian|Pukrop, Tobias|Koenig, Sarah
PMID: 27338550
Journal: Oncogene. 2016 Nov 10;35(45):5839-5849.
Title: Intestinal knockout of Nedd4 enhances growth of Apc(min) tumors.
Author: Lu, C|Thoeni, C|Connor, A|Kawabe, H|Gallinger, S|Rotin, D
PMID: 27086928
Journal: Oncogene. 2016 Sep 22;35(38):4990-9.
Title: Topoisomerase IIalpha mediates TCF-dependent epithelial-mesenchymal transition in colon cancer.
Author: Zhou, Q|Abraham, A D|Li, L|Babalmorad, A|Bagby, S|Arcaroli, J J|Hansen, R J|Valeriote, F A|Gustafson, D L|Schaack, J|Messersmith, W A|LaBarbera, D V
PMID: 26947016
Journal: Oncogene. 2016 Jun 30;35(26):3410-8.
Title: Positive regulation of beta-catenin-PROX1 signaling axis by DBC1 in colon cancer progression.
Author: Yu, E J|Kim, S-H|Kim, H J|Heo, K|Ou, C-Y|Stallcup, M R|Kim, J H
PMID: 26477307
Journal: Oncotarget. 2016 Jul 5;7(27):42513-42526.
Title: Wnt/beta-catenin pathway transactivates microRNA-150 that promotes EMT of colorectal cancer cells by suppressing CREB signaling.
Author: Guo, Yan-Hua|Wang, Lu-Qin|Li, Bin|Xu, Hui|Yang, Jian-Hua|Zheng, Li-Si|Yu, Peng|Zhou, Ai-Dong|Zhang, Yin|Xie, Shu-Juan|Liang, Zi-Rui|Zhang, Chen-Min|Zhou, Hui|Qu, Liang-Hu
PMID: 27285761
Journal: Contemp Oncol (Pozn). 2017;21(2):136-144.
Title: Network analysis based on TCGA reveals hub genes in colon cancer.
Author: Wu, Fenzan|Yuan, Guoping|Chen, Junjie|Wang, Chengzu
PMID: 28947883
Journal: BMC Genet. 2017 Dec 28;18(Suppl 1):117.
Title: Upregulation of NETO2 gene in colorectal cancer.
Author: Fedorova, Maria S|Snezhkina, Anastasiya V|Pudova, Elena A|Abramov, Ivan S|Lipatova, Anastasiya V|Kharitonov, Sergey L|Sadritdinova, Asiya F|Nyushko, Kirill M|Klimina, Kseniya M|Belyakov, Mikhail M|Slavnova, Elena N|Melnikova, Nataliya V|Chernichenko, Mari
PMID: 29297384
Journal: Oncotarget. 2017 Aug 5;8(41):70854-70864.
Title: Different effection of p.1125Val>Ala and rs11954856 in APC on Wnt signaling pathway.
Author: Li, Fei-Feng|Zhao, Zhi-Xun|Yan, Peng|Wang, Song|Liu, Zheng|Zhang, Qiong|Zhang, Xiao-Ning|Sun, Chang-Hao|Wang, Xi-Shan|Wang, Gui-Yu|Liu, Shu-Lin
PMID: 29050326
Journal: Cancer Med. 2017 Oct;6(10):2321-2330.
Title: Identification of dysregulated lncRNAs profiling and metastasis-associated lncRNAs in colorectal cancer by genome-wide analysis.
Author: Chen, Yan|Yu, Xiang|Xu, Yongcan|Shen, Hua
PMID: 28857495
Journal: Cancer Sci. 2017 Oct;108(10):1985-1995.
Title: microRNA-219-5p inhibits epithelial-mesenchymal transition and metastasis of colorectal cancer by targeting lymphoid enhancer-binding factor 1.
Author: Huang, Lan-Xuan|Hu, Chun-Yan|Jing, Li|Wang, Min-Cong|Xu, Meng|Wang, Jing|Wang, Yu|Nan, Ke-Jun|Wang, Shu-Hong
PMID: 28771881
Journal: Am J Cancer Res. 2017 Jun 1;7(6):1389-1406. eCollection 2017.
Title: Wnt signaling pathway protein LEF1 in cancer, as a biomarker for prognosis and a target for treatment.
Author: Santiago, Larion|Daniels, Garrett|Wang, Dongwen|Deng, Fang-Ming|Lee, Peng
PMID: 28670499
Journal: Cancer Lett. 2017 Sep 10;403:86-97.
Title: Tanshinone IIA inhibits beta-catenin/VEGF-mediated angiogenesis by targeting TGF-beta1 in normoxic and HIF-1alpha in hypoxic microenvironments in human colorectal cancer.
Author: Sui, Hua|Zhao, Jihui|Zhou, Lihong|Wen, Haotian|Deng, Wanli|Li, Chunpu|Ji, Qing|Liu, Xuan|Feng, Yuanyuan|Chai, Ni|Zhang, Qibo|Cai, Jianfeng|Li, Qi
PMID: 28602978
Journal: Int J Mol Sci. 2017 May 25;18(6). pii: ijms18061132.
Title: Prostaglandin E2-Induced COX-2 Expressions via EP2 and EP4 Signaling Pathways in Human LoVo Colon Cancer Cells.
Author: Hsu, Hsi-Hsien|Lin, Yueh-Min|Shen, Chia-Yao|Shibu, Marthandam Asokan|Li, Shin-Yi|Chang, Sheng-Huang|Lin, Chien-Chung|Chen, Ray-Jade|Viswanadha, Vijaya Padma|Shih, Hui-Nung|Huang, Chih-Yang
PMID: 28587064
Journal: World J Gastroenterol. 2017 Feb 21;23(7):1171-1179.
Title: Thymoquinone suppresses migration of LoVo human colon cancer cells by reducing prostaglandin E2 induced COX-2 activation.
Author: Hsu, Hsi-Hsien|Chen, Ming-Cheng|Day, Cecilia Hsuan|Lin, Yueh-Min|Li, Shin-Yi|Tu, Chuan-Chou|Padma, Viswanadha Vijaya|Shih, Hui-Nung|Kuo, Wei-Wen|Huang, Chih-Yang
PMID: 28275297
Journal: Mol Carcinog. 2017 Nov;56(11):2372-2381.
Title: Differential expression of LEF1/TCFs family members in colonic carcinogenesis.
Author: Han, Wenxiao|He, Longmei|Cao, Bangrong|Zhao, Xinhua|Zhang, Kaitai|Li, Yan|Beck, Paul|Zhou, Zhixiang|Tian, Yantao|Cheng, Shujun|Wang, Hongying
PMID: 27433921
Journal: Cancer Lett. 2018 Jun 28;424:9-18.
Title: The intestinal stem cell regulating gene ASCL2 is required for L1-mediated colon cancer progression.
Author: Basu, Sayon|Gavert, Nancy|Brabletz, Thomas|Ben-Ze'ev, Avri
PMID: 29551399
Journal: Int J Mol Med. 2018 Aug;42(2):713-725.
Title: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review).
Author: Katoh, Masaru
PMID: 29786110
Journal: Cell Death Dis. 2018 Aug 6;9(8):831.
Title: DBC1 regulates Wnt/beta-catenin-mediated expression of MACC1, a key regulator of cancer progression, in colon cancer.
Author: Kim, Hwa Jin|Moon, Sue Jin|Kim, Seok-Hyung|Heo, Kyu|Kim, Jeong Hoon
PMID: 30082743
Journal: Gene. 2018 Sep 4;679:150-159.
Title: An integrated study on TFs and miRNAs in colorectal cancer metastasis and evaluation of three co-regulated candidate genes as prognostic markers.
Author: Eskandari, Elaheh|Mahjoubi, Frouzandeh|Motalebzadeh, Jamshid
PMID: 30193961
Journal: Med Sci Monit. 2018 Sep 19;24:6608-6616.
Title: Elevated G-Protein Receptor 125 (GPR125) Expression Predicts Good Outcomes in Colorectal Cancer and Inhibits Wnt/beta-Catenin Signaling Pathway.
Author: Wu, Yibin|Chen, Wenjie|Gong, Lifeng|Ke, Chongwei|Wang, Huipeng|Cai, Yuankun
PMID: 30231258
Journal: J Exp Clin Cancer Res. 2018 Sep 25;37(1):238.
Title: MiR-452 promotes an aggressive colorectal cancer phenotype by regulating a Wnt/beta-catenin positive feedback loop.
Author: Li, Tingting|Jian, Xiangyu|He, Han|Lai, Qiuhua|Li, Xianzheng|Deng, Danling|Liu, Tengfei|Zhu, Jiehong|Jiao, Hongli|Ye, Yaping|Wang, Shuyang|Yang, Minhui|Zheng, Lin|Zhou, Weijie|Ding, Yanqing
PMID: 30253791
Journal: Oncotarget. 2018 Sep 21;9(74):33982-33994.
Title: Sulforaphane inhibits growth and blocks Wnt/beta-catenin signaling of colorectal cancer cells.
Author: Bernkopf, Dominic B|Daum, Gabriele|Bruckner, Martina|Behrens, Jurgen
PMID: 30338040
Journal: Cancer Biomark. 2018 Oct 9. pii: CBM181703.
Title: NUP153 overexpression suppresses the proliferation of colorectal cancer by negatively regulating Wnt/beta-catenin signaling pathway and predicts good prognosis.
Author: Wu, Yibin|Fang, Guojiu|Wang, Xin|Wang, Huipeng|Chen, Wenjie|Li, Liang|Ye, Tao|Gong, Lifeng|Ke, Chongwei|Cai, Yuankun
PMID: 30347601