Primary Site >> Liver Cancer

Gene >> LECT2

Journal: Pathol Int. 1999 Feb;49(2):147-51.
Title: Expression pattern of a newly recognized protein, LECT2, in hepatocellular carcinoma and its premalignant lesion.
Author: Uchida, T|Nagai, H|Gotoh, K|Kanagawa, H|Kouyama, H|Kawanishi, T|Mima, S|Yamagoe, S|Suzuki, K
PMID: 10355968
Journal: Oncogene. 2007 Feb 1;26(5):774-80.
Title: Differential effects of inactivated Axin1 and activated beta-catenin mutations in human hepatocellular carcinomas.
Author: Zucman-Rossi, J|Benhamouche, S|Godard, C|Boyault, S|Grimber, G|Balabaud, C|Cunha, A S|Bioulac-Sage, P|Perret, C
PMID: 16964294
Journal: Cancer Gene Ther. 2011 Jun;18(6):399-406.
Title: The tumor suppressor function of LECT2 in human hepatocellular carcinoma makes it a potential therapeutic target.
Author: Ong, H T|Tan, P K|Wang, S M|Hian Low, D T|Ooi, L L P J|Hui, K M
PMID: 21394108
Journal: J Clin Invest. 2012 Feb;122(2):586-99.
Title: Oncogenic beta-catenin triggers an inflammatory response that determines the aggressiveness of hepatocellular carcinoma in mice.
Author: Anson, Marie|Crain-Denoyelle, Anne-Marie|Baud, Veronique|Chereau, Fanny|Gougelet, Angelique|Terris, Benoit|Yamagoe, Satoshi|Colnot, Sabine|Viguier, Mireille|Perret, Christine|Couty, Jean-Pierre
PMID: 22251704
Journal: Hepatology. 2014 Mar;59(3):974-85.
Title: Leukocyte cell-derived chemotaxin 2 antagonizes MET receptor activation to suppress hepatocellular carcinoma vascular invasion by protein tyrosine phosphatase 1B recruitment.
Author: Chen, Chi-Kuan|Yang, Ching-Yao|Hua, Kuo-Tai|Ho, Ming-Chih|Johansson, Gunnar|Jeng, Yung-Ming|Chen, Chiung-Nien|Chen, Min-Wei|Lee, Wei-Jiunn|Su, Jen-Liang|Lai, Tsung-Ching|Chou, Chi-Chi|Ho, Bing-Ching|Chang, Chuan-Fa|Lee, Po-Huang|Chang, King-Jen|Hsiao, Mic
PMID: 24114941
Journal: PLoS One. 2014 Jun 3;9(6):e98817.
Title: Role of leukocyte cell-derived chemotaxin 2 as a biomarker in hepatocellular carcinoma.
Author: Okabe, Hirohisa|Delgado, Evan|Lee, Jung Min|Yang, Jing|Kinoshita, Hiroki|Hayashi, Hiromitsu|Tsung, Allan|Behari, Jaideep|Beppu, Toru|Baba, Hideo|Monga, Satdarshan P
PMID: 24892551
Journal: PLoS One. 2016 Apr 21;11(4):e0152695.
Title: Diverse Basis of beta-Catenin Activation in Human Hepatocellular Carcinoma: Implications in Biology and Prognosis.
Author: Okabe, Hirohisa|Kinoshita, Hiroki|Imai, Katsunori|Nakagawa, Shigeki|Higashi, Takaaki|Arima, Kota|Uchiyama, Hideaki|Ikegami, Toru|Harimoto, Norifumi|Itoh, Shinji|Ishiko, Takatoshi|Yoshizumi, Tomoharu|Beppu, Toru|Monga, Satdarshan P S|Baba, Hideo|Maehara, Y
PMID: 27100093
Journal: J Biol Chem. 2016 Aug 12;291(33):17133-42.
Title: Crystal Structure of Human Leukocyte Cell-derived Chemotaxin 2 (LECT2) Reveals a Mechanistic Basis of Functional Evolution in a Mammalian Protein with an M23 Metalloendopeptidase Fold.
Author: Zheng, Hai|Miyakawa, Takuya|Sawano, Yoriko|Asano, Atsuko|Okumura, Akinori|Yamagoe, Satoshi|Tanokura, Masaru
PMID: 27334921
Journal: Sci Rep. 2016 Aug 10;6:31398.
Title: Inhibition of VEGF165/VEGFR2-dependent signaling by LECT2 suppresses hepatocellular carcinoma angiogenesis.
Author: Chen, Chi-Kuan|Yu, Wen-Hsuan|Cheng, Tsu-Yao|Chen, Min-Wei|Su, Chia-Yi|Yang, Yi-Chieh|Kuo, Tsang-Chih|Lin, Ming-Tsan|Huang, Ya-Chi|Hsiao, Michael|Hua, Kuo-Tai|Hung, Mien-Chie|Kuo, Min-Liang
PMID: 27507763
Journal: Hepatology. 2018 Aug 2.
Title: Lect2 controls inflammatory monocytes to constrain the growth and progression of hepatocellular carcinoma.
Author: L'Hermitte, Antoine|Pham, Sandrine|Cadoux, Mathilde|Couchy, Gabrielle|Caruso, Stefano|Anson, Marie|Crain-Denoyelle, Anne-Marie|Celton-Morizur, Severine|Yamagoe, Satoshi|Zucman-Rossi, Jessica|Desdouets, Chantal|Couty, Jean-Pierre
PMID: 30070727
Journal: Am J Pathol. 2018 Sep 8. pii: S0002-9440(17)31145-8.
Title: High Frequency of beta-Catenin Mutations in Mouse Hepatocellular Carcinomas Induced by a Nongenotoxic Constitutive Androstane Receptor Agonist.
Author: Mattu, Sandra|Saliba, Christian|Sulas, Pia|Zavattari, Patrizia|Perra, Andrea|Kowalik, Marta A|Monga, Satdarshan P|Columbano, Amedeo
PMID: 30201494