Primary Site >> Colorectal Cancer

Gene >> LDHA

Journal: J Natl Cancer Inst. 1982 Jan;68(1):81-90.
Title: Various isozyme gene expression patterns among human colorectal adenocarcinoma cell lines and tissues.
Author: Rutzky, L P|Siciliano, M J
PMID: 6948128
Journal: Pharmacogenomics. 2007 Dec;8(12):1705-13.
Title: Serum lactate dehydrogenase levels and glycolysis significantly correlate with tumor VEGFA and VEGFR expression in metastatic CRC patients.
Author: Azuma, Mizutomo|Shi, Michael|Danenberg, Kathleen D|Gardner, Humphrey|Barrett, Carl|Jacques, Christian J|Sherod, Andrew|Iqbal, Syma|El-Khoueiry, Anthony|Yang, Dongyun|Zhang, Wu|Danenberg, Peter V|Lenz, Heinz-Josef
PMID: 18086000
Journal: Mol Cell Proteomics. 2011 Aug;10(8):M111.010462.
Title: Genome-wide characterization of miR-34a induced changes in protein and mRNA expression by a combined pulsed SILAC and microarray analysis.
Author: Kaller, Markus|Liffers, Sven-Thorsten|Oeljeklaus, Silke|Kuhlmann, Katja|Roh, Simone|Hoffmann, Reinhard|Warscheid, Bettina|Hermeking, Heiko
PMID: 21566225
Journal: Clin Cancer Res. 2011 Jul 15;17(14):4892-900.
Title: Prognostic and predictive role of lactate dehydrogenase 5 expression in colorectal cancer patients treated with PTK787/ZK 222584 (vatalanib) antiangiogenic therapy.
Author: Koukourakis, Michael I|Giatromanolaki, Alexandra|Sivridis, Efthimios|Gatter, Kevin C|Trarbach, Tanja|Folprecht, Gunnar|Shi, Michael M|Lebwohl, David|Jalava, Tarja|Laurent, Dirk|Meinhardt, Gerold|Harris, Adrian L
PMID: 21632858
Journal: PLoS Genet. 2012;8(3):e1002573.
Title: Mouse genetics suggests cell-context dependency for Myc-regulated metabolic enzymes during tumorigenesis.
Author: Nilsson, Lisa M|Forshell, Tacha Zi Plym|Rimpi, Sara|Kreutzer, Christiane|Pretsch, Walter|Bornkamm, Georg W|Nilsson, Jonas A
PMID: 22438825
Journal: Pharmacogenomics J. 2013 Oct;13(5):410-6.
Title: Intratumoral expression profiling of genes involved in angiogenesis in colorectal cancer patients treated with chemotherapy plus the VEGFR inhibitor PTK787/ZK 222584 (vatalanib).
Author: Wilson, P M|Yang, D|Azuma, M|Shi, M M|Danenberg, K D|Lebwohl, D|Sherrod, A|Ladner, R D|Zhang, W|Danenberg, P V|Trarbach, T|Folprecht, G|Meinhardt, G|Lenz, H-J
PMID: 22664478
Journal: Mol Carcinog. 2014 Feb;53 Suppl 1:E107-18.
Title: Wogonin reverses hypoxia resistance of human colon cancer HCT116 cells via downregulation of HIF-1alpha and glycolysis, by inhibiting PI3K/Akt signaling pathway.
Author: Wang, Hu|Zhao, Li|Zhu, Li-Tao|Wang, Yu|Pan, Di|Yao, Jing|You, Qi-Dong|Guo, Qing-Long
PMID: 23761018
Journal: Oncotarget. 2015 Sep 22;6(28):26161-76.
Title: Tumor suppressor NDRG2 inhibits glycolysis and glutaminolysis in colorectal cancer cells by repressing c-Myc expression.
Author: Xu, Xinyuan|Li, Jianying|Sun, Xiang|Guo, Yan|Chu, Dake|Wei, Li|Li, Xia|Yang, Guodong|Liu, Xinping|Yao, Libo|Zhang, Jian|Shen, Lan
PMID: 26317652
Journal: Cell Rep. 2016 Oct 11;17(3):821-836.
Title: Addiction to Coupling of the Warburg Effect with Glutamine Catabolism in Cancer Cells.
Author: Smith, Bradley|Schafer, Xenia L|Ambeskovic, Aslihan|Spencer, Cody M|Land, Hartmut|Munger, Joshua
PMID: 27732857
Journal: Oncotarget. 2016 Oct 4;7(40):65454-65470.
Title: Hypoxia-responsive miR-210 promotes self-renewal capacity of colon tumor-initiating cells by repressing ISCU and by inducing lactate production.
Author: Ullmann, Pit|Qureshi-Baig, Komal|Rodriguez, Fabien|Ginolhac, Aurelien|Nonnenmacher, Yannic|Ternes, Dominik|Weiler, Jil|Gabler, Karoline|Bahlawane, Christelle|Hiller, Karsten|Haan, Serge|Letellier, Elisabeth
PMID: 27589845
Journal: Mol Pharm. 2016 Jul 5;13(7):2497-506.
Title: Dynamic Contrast Enhanced MRI Assessing the Antiangiogenic Effect of Silencing HIF-1alpha with Targeted Multifunctional ECO/siRNA Nanoparticles.
Author: Malamas, Anthony S|Jin, Erlei|Gujrati, Maneesh|Lu, Zheng-Rong
PMID: 27264671
Journal: Oncotarget. 2017 Mar 28;8(13):20543-20557.
Title: Metabolic reprogramming of the premalignant colonic mucosa is an early event in carcinogenesis.
Author: Cruz, Mart Dela|Ledbetter, Sarah|Chowdhury, Sanjib|Tiwari, Ashish K|Momi, Navneet|Wali, Ramesh K|Bliss, Charles|Huang, Christopher|Lichtenstein, David|Bhattacharya, Swati|Varma-Wilson, Anisha|Backman, Vadim|Roy, Hemant K
PMID: 28423551
Journal: Nat Commun. 2017 May 18;8:15308.
Title: Adenylate kinase hCINAP determines self-renewal of colorectal cancer stem cells by facilitating LDHA phosphorylation.
Author: Ji, Yapeng|Yang, Chuanzhen|Tang, Zefang|Yang, Yongfeng|Tian, Yonglu|Yao, Hongwei|Zhu, Xi|Zhang, Zeming|Ji, Jiafu|Zheng, Xiaofeng
PMID: 28516914
Journal: Nat Commun. 2017 Jun 16;8:16000.
Title: Corrigendum: Adenylate kinase hCINAP determines self-renewal of colorectal cancer stem cells by facilitating LDHA phosphorylation.
Author: Ji, Yapeng|Yang, Chuanzhen|Tang, Zefang|Yang, Yongfeng|Tian, Yonglu|Yao, Hongwei|Zhu, Xi|Zhang, Zemin|Ji, Jiafu|Zheng, Xiaofeng
PMID: 28621309
Journal: Int J Oncol. 2017 Oct;51(4):1271-1279.
Title: PRL-3 improves colorectal cancer cell proliferation and invasion through IL-8 mediated glycolysis metabolism.
Author: Xu, Heyang|Zeng, Yujie|Liu, Lu|Gao, Qian|Jin, Shaowen|Lan, Qiusheng|Lai, Wei|Luo, Xingxi|Wu, Heng|Huang, Yongliang|Chu, Zhonghua
PMID: 28791350
Journal: Oncol Lett. 2018 Apr;15(4):5553-5560.
Title: Effect of HK2, PKM2 and LDHA on Cetuximab efficacy in metastatic colorectal cancer.
Author: Wang, Haohua|Peng, Roujun|Chen, Xiuxing|Jia, Rui|Huang, Chunyue|Huang, Yuanyuan|Xia, Liangping|Guo, Guifang
PMID: 29552193
Journal: Oncol Rep. 2018 May;39(5):2436-2442.
Title: Berberine decelerates glucose metabolism via suppression of mTORdependent HIF1alpha protein synthesis in colon cancer cells.
Author: Mao, Liyuan|Chen, Qiongyun|Gong, Ke|Xu, Xiaolin|Xie, Yurou|Zhang, Wenqing|Cao, Hanwei|Hu, Tianhui|Hong, Xiaoting|Zhan, Yan-Yan
PMID: 29565467
Journal: Biosci Rep. 2018 Jul 2;38(4). pii: BSR20180580.
Title: Chemokine (C-X-C motif) ligand 1 is associated with tumor progression and poor prognosis in patients with colorectal cancer.
Author: Zhuo, Changhua|Wu, Xianyi|Li, Jing|Hu, Dan|Jian, Jinliang|Chen, Changjiang|Zheng, Xiongwei|Yang, Chunkang
PMID: 29784873
Journal: J Cell Biochem. 2018 Jul 17.
Title: Protein kinase CK2 modulation of pyruvate kinase M isoforms augments the Warburg effect in cancer cells.
Author: Yang, Kyung Mi|Kim, Kunhong
PMID: 30015359
Journal: J Am Soc Mass Spectrom. 2018 Oct;29(10):2012-2022.
Title: Combined Short-Term Glucose Starvation and Chemotherapy in 3D Colorectal Cancer Cell Culture Decreases 14-3-3 Family Protein Expression and Phenotypic Response to Therapy.
Author: Schroll, Monica M|Ludwig, Katelyn R|LaBonia, Gabriel J|Herring, Emily L|Hummon, Amanda B
PMID: 30019162