Primary Site >> Colorectal Cancer
Gene >> LDHA
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Ref: Various isozyme gene expression patterns among human colorectal adenocarcinoma cell lines and tissues. PMID: 6948128 |
Ref: Serum lactate dehydrogenase levels and glycolysis significantly correlate with tumor VEGFA and VEGFR expression in metastatic CRC patients. PMID: 18086000 |
Ref: Genome-wide characterization of miR-34a induced changes in protein and mRNA expression by a combined pulsed SILAC and microarray analysis. PMID: 21566225 Ref: Prognostic and predictive role of lactate dehydrogenase 5 expression in colorectal cancer patients treated with PTK787/ZK 222584 (vatalanib) antiangiogenic therapy. PMID: 21632858 |
Ref: Mouse genetics suggests cell-context dependency for Myc-regulated metabolic enzymes during tumorigenesis. PMID: 22438825 |
Ref: Intratumoral expression profiling of genes involved in angiogenesis in colorectal cancer patients treated with chemotherapy plus the VEGFR inhibitor PTK787/ZK 222584 (vatalanib). PMID: 22664478 |
Ref: Wogonin reverses hypoxia resistance of human colon cancer HCT116 cells via downregulation of HIF-1alpha and glycolysis, by inhibiting PI3K/Akt signaling pathway. PMID: 23761018 |
Ref: Tumor suppressor NDRG2 inhibits glycolysis and glutaminolysis in colorectal cancer cells by repressing c-Myc expression. PMID: 26317652 |
Ref: Dynamic Contrast Enhanced MRI Assessing the Antiangiogenic Effect of Silencing HIF-1alpha with Targeted Multifunctional ECO/siRNA Nanoparticles. PMID: 27264671 Ref: Hypoxia-responsive miR-210 promotes self-renewal capacity of colon tumor-initiating cells by repressing ISCU and by inducing lactate production. PMID: 27589845 Ref: Addiction to Coupling of the Warburg Effect with Glutamine Catabolism in Cancer Cells. PMID: 27732857 |
Ref: Metabolic reprogramming of the premalignant colonic mucosa is an early event in carcinogenesis. PMID: 28423551 Ref: Adenylate kinase hCINAP determines self-renewal of colorectal cancer stem cells by facilitating LDHA phosphorylation. PMID: 28516914 Ref: Corrigendum: Adenylate kinase hCINAP determines self-renewal of colorectal cancer stem cells by facilitating LDHA phosphorylation. PMID: 28621309 Ref: PRL-3 improves colorectal cancer cell proliferation and invasion through IL-8 mediated glycolysis metabolism. PMID: 28791350 |
Ref: Effect of HK2, PKM2 and LDHA on Cetuximab efficacy in metastatic colorectal cancer. PMID: 29552193 Ref: Berberine decelerates glucose metabolism via suppression of mTORdependent HIF1alpha protein synthesis in colon cancer cells. PMID: 29565467 Ref: Chemokine (C-X-C motif) ligand 1 is associated with tumor progression and poor prognosis in patients with colorectal cancer. PMID: 29784873 Ref: Protein kinase CK2 modulation of pyruvate kinase M isoforms augments the Warburg effect in cancer cells. PMID: 30015359 Ref: Combined Short-Term Glucose Starvation and Chemotherapy in 3D Colorectal Cancer Cell Culture Decreases 14-3-3 Family Protein Expression and Phenotypic Response to Therapy. PMID: 30019162 |