Primary Site >> Colorectal Cancer

Gene >> LCK

Journal: Oncogene Res. 1987 Sep-Oct;1(4):357-74.
Title: Expression of the lck tyrosine kinase gene in human colon carcinoma and other non-lymphoid human tumor cell lines.
Author: Veillette, A|Foss, F M|Sausville, E A|Bolen, J B|Rosen, N
PMID: 2835736
Journal: Oncogene Res. 1989;5(1):13-23.
Title: Alterations in the expression of pp60c-src and p56lck associated with butyrate-induced differentiation of human colon carcinoma cells.
Author: Foss, F M|Veillette, A|Sartor, O|Rosen, N|Bolen, J B
PMID: 2476706
Journal: Mol Cell Biol. 1989 May;9(5):2173-80.
Title: Structure of the two promoters of the human lck gene: differential accumulation of two classes of lck transcripts in T cells.
Author: Takadera, T|Leung, S|Gernone, A|Koga, Y|Takihara, Y|Miyamoto, N G|Mak, T W
PMID: 2787474
Journal: Science. 1992 Dec 11;258(5089):1795-8.
Title: Alterations in signal transduction molecules in T lymphocytes from tumor-bearing mice.
Author: Mizoguchi, H|O'Shea, J J|Longo, D L|Loeffler, C M|McVicar, D W|Ochoa, A C
PMID: 1465616
Journal: Oncogene. 1993 Oct;8(10):2627-35.
Title: c-Yes tyrosine kinase activity in human colon carcinoma.
Author: Park, J|Meisler, A I|Cartwright, C A
PMID: 7690925
Journal: Oncogene. 1993 Apr;8(4):989-97.
Title: Requirement of an ETS-binding element for transcription of the human lck type I promoter.
Author: Leung, S|McCracken, S|Ghysdael, J|Miyamoto, N G
PMID: 8455950
Journal: Int J Oncol. 1993 Aug;3(2):369-73.
Title: An essential cis-acting element of the lck-3' promoter regulates the expression of p56(lck) in metastatic colorectal-cancer cells.
Author: Mayer, K|Ballhausen, W
PMID: 21573376
Journal: J Biol Chem. 1995 Nov 17;270(46):27538-43.
Title: Identification of a novel repressive element in the proximal lck promoter.
Author: Muise-Helmericks, R C|Rosen, N
PMID: 7499213
Journal: Anticancer Res. 1996 Jul-Aug;16(4A):1733-7.
Title: Expression of alternatively spliced lck transcripts from the proximal promoter in colorectal cancer derived cell lines.
Author: Mayer, K|Ballhausen, W G
PMID: 8712692
Journal: Eur J Cancer. 1996 Jul;32A(8):1401-7.
Title: Augmented expression of LCK message directed from the downstream promoter in human colorectal cancer specimens.
Author: Nakamura, K|Chijiiwa, Y|Nawata, H
PMID: 8869106
Journal: Int J Cancer. 1997 Aug 7;72(4):625-30.
Title: Ectopic activation of lymphoid high mobility group-box transcription factor TCF-1 and overexpression in colorectal cancer cells.
Author: Mayer, K|Hieronymus, T|Castrop, J|Clevers, H|Ballhausen, W G
PMID: 9259402
Journal: Oncogene. 1997 Dec 11;15(24):2929-37.
Title: An alternative pathway for expression of p56lck from type I promoter transcripts in colon carcinoma.
Author: McCracken, S|Kim, C S|Xu, Y|Minden, M|Miyamoto, N G
PMID: 9416836
Journal: Clin Cancer Res. 1998 Oct;4(10):2337-47.
Title: Signal transduction abnormalities in T lymphocytes from patients with advanced renal carcinoma: clinical relevance and effects of cytokine therapy.
Author: Bukowski, R M|Rayman, P|Uzzo, R|Bloom, T|Sandstrom, K|Peereboom, D|Olencki, T|Budd, G T|McLain, D|Elson, P|Novick, A|Finke, J H
PMID: 9796963
Journal: Cancer Immunol Immunother. 1998 Jun;46(4):185-93.
Title: Adjuvant adoptive immunotherapy with tumour-infiltrating lymphocytes and modulated doses of interleukin-2 in 22 patients with melanoma, colorectal and renal cancer, after radical metastasectomy, and in 12 advanced patients.
Author: Ridolfi, R|Flamini, E|Riccobon, A|De Paola, F|Maltoni, R|Gardini, A|Ridolfi, L|Medri, L|Poletti, G|Amadori, D
PMID: 9671141
Journal: Cancer Immunol Immunother. 1998 Feb;45(6):299-305.
Title: Alteration of signal-transducing molecules in tumor-infiltrating lymphocytes and peripheral blood T lymphocytes from human colorectal carcinoma patients.
Author: Choi, S H|Chung, E J|Whang, D Y|Lee, S S|Jang, Y S|Kim, C W
PMID: 9490199
Journal: Bioconjug Chem. 1999 Sep-Oct;10(5):781-90.
Title: Carrier design: new generation of polycationic branched polypeptides containing OH groups with prolonged blood survival and diminished in vitro cytotoxicity.
Author: Hudecz, F|Pimm, M V|Rajnavolgyi, E|Mezo, G|Fabra, A|Gaal, D|Kovacs, A L|Horvath, A|Szekerke, M
PMID: 10502343
Journal: Biochem Pharmacol. 2000 Oct 1;60(7):885-98.
Title: Biochemical and cellular effects of c-Src kinase-selective pyrido[2, 3-d]pyrimidine tyrosine kinase inhibitors.
Author: Kraker, A J|Hartl, B G|Amar, A M|Barvian, M R|Showalter, H D|Moore, C W
PMID: 10974196
Journal: Cancer Chemother Pharmacol. 2000;46(3):246-50.
Title: Preclinical oral antitumor activity of BMS-185660, a paclitaxel derivative.
Author: Rose, W C|Lee, F Y|Golik, J|Kadow, J
PMID: 11021743
Journal: Br J Cancer. 2003 Jan 27;88(2):320-6.
Title: Restored T-cell activation mechanisms in human tumour-infiltrating lymphocytes from melanomas and colorectal carcinomas after exposure to interleukin-2.
Author: De Paola, F|Ridolfi, R|Riccobon, A|Flamini, E|Barzanti, F|Granato, A M|Mordenti, G L|Medri, L|Vitali, P|Amadori, D
PMID: 12610520
Journal: Int J Cancer. 2006 Feb 1;118(3):547-54.
Title: Src family kinase members have a common response to histone deacetylase inhibitors in human colon cancer cells.
Author: Hirsch, Calley L|Smith-Windsor, Erin L|Bonham, Keith
PMID: 16094635
Journal: Neurosignals. 2008;16(2-3):235-45.
Title: Tyrosine phosphorylation of netrin receptors in netrin-1 signaling.
Author: Ren, Xiu-Rong|Hong, Yan|Feng, Zhu|Yang, Hong-Mei|Mei, Lin|Xiong, Wen-Cheng
PMID: 18253061
Journal: Cell Commun Signal. 2008 Oct 9;6:7.
Title: Odin (ANKS1A) is a Src family kinase target in colorectal cancer cells.
Author: Emaduddin, Muhammad|Edelmann, Mariola J|Kessler, Benedikt M|Feller, Stephan M
PMID: 18844995
Journal: Eur J Cancer. 2010 Jul;46(11):2119-26.
Title: Prediction of liver metastasis after colorectal cancer using reverse transcription-polymerase chain reaction analysis of 10 genes.
Author: Watanabe, Toshiaki|Kobunai, Takashi|Yamamoto, Yoko|Kanazawa, Takamitsu|Konishi, Tsuyoshi|Tanaka, Toshiaki|Matsuda, Keiji|Ishihara, Soichiro|Nozawa, Keijiro|Eshima, Kiyoshi|Muto, Tetsuichiro|Nagawa, Hirokazu
PMID: 20570135
Journal: Leuk Lymphoma. 2010 Oct;51(10):1875-86.
Title: Conditional inactivation of MLH1 in thymic and naive T-cells in mice leads to a limited incidence of lymphoblastic T-cell lymphomas.
Author: Reiss, Cora|Haneke, Torsten|Volker, Hans-Ulrich|Spahn, Martin|Rosenwald, Andreas|Edelmann, Winfried|Kneitz, Burkhard
PMID: 20858091
Journal: Invest New Drugs. 2011 Jun;29(3):424-33.
Title: Preclinical investigation of tolerance and antitumour activity of new fluorodeoxyglucose-coupled chlorambucil alkylating agents.
Author: Miot-Noirault, Elisabeth|Reux, Bastien|Debiton, Eric|Madelmont, Jean-Claude|Chezal, Jean-Michel|Coudert, Pascal|Weber, Valerie
PMID: 20033262
Journal: Clin Cancer Res. 2011 Sep 1;17(17):5546-52.
Title: Inhibition of SRC family kinases and receptor tyrosine kinases by dasatinib: possible combinations in solid tumors.
Author: Montero, Juan Carlos|Seoane, Samuel|Ocana, Alberto|Pandiella, Atanasio
PMID: 21670084
Journal: Ann Surg Oncol. 2017 Dec;24(13):4051-4058.
Title: Proteomic Features of Colorectal Cancer Identify Tumor Subtypes Independent of Oncogenic Mutations and Independently Predict Relapse-Free Survival.
Author: Clarke, Callisia N|Lee, Michael S|Wei, Wei|Manyam, Ganiraju|Jiang, Zhi-Qin|Lu, Yiling|Morris, Jeffrey|Broom, Bradley|Menter, David|Vilar-Sanchez, Eduardo|Raghav, Kanwal|Eng, Cathy|Chang, George J|Simon, Iris|Bernards, Rene|Overman, Michael|Mills, Gordon B
PMID: 28936799
Journal: Carcinogenesis. 2018 Jan 12;39(1):36-46.
Title: Potent suppression of both spontaneous and carcinogen-induced colitis-associated colorectal cancer in mice by dietary celastrol supplementation.
Author: Barker, Emily C|Kim, Byung-Gyu|Yoon, Ji Hee|Tochtrop, Gregory P|Letterio, John J|Choi, Sung Hee
PMID: 29069290
Journal: Cancer Biomark. 2018;22(1):89-99.
Title: Potential biomarkers for the early diagnosis of colorectal adenocarcinoma - transcriptomic analysis of four clinical stages.
Author: Janikowska, Grazyna|Janikowski, Tomasz|Pyka-Pajak, Alina|Mazurek, Urszula|Janikowski, Marcin|Gonciarz, Maciej|Lorenc, Zbigniew
PMID: 29562499