Primary Site >> Colorectal Cancer
Gene >> LCK
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Ref: Expression of the lck tyrosine kinase gene in human colon carcinoma and other non-lymphoid human tumor cell lines. PMID: 2835736 |
Ref: Alterations in the expression of pp60c-src and p56lck associated with butyrate-induced differentiation of human colon carcinoma cells. PMID: 2476706 Ref: Structure of the two promoters of the human lck gene: differential accumulation of two classes of lck transcripts in T cells. PMID: 2787474 |
Ref: Alterations in signal transduction molecules in T lymphocytes from tumor-bearing mice. PMID: 1465616 |
Ref: c-Yes tyrosine kinase activity in human colon carcinoma. PMID: 7690925 Ref: Requirement of an ETS-binding element for transcription of the human lck type I promoter. PMID: 8455950 Ref: An essential cis-acting element of the lck-3' promoter regulates the expression of p56(lck) in metastatic colorectal-cancer cells. PMID: 21573376 |
Ref: Identification of a novel repressive element in the proximal lck promoter. PMID: 7499213 |
Ref: Expression of alternatively spliced lck transcripts from the proximal promoter in colorectal cancer derived cell lines. PMID: 8712692 Ref: Augmented expression of LCK message directed from the downstream promoter in human colorectal cancer specimens. PMID: 8869106 |
Ref: Ectopic activation of lymphoid high mobility group-box transcription factor TCF-1 and overexpression in colorectal cancer cells. PMID: 9259402 Ref: An alternative pathway for expression of p56lck from type I promoter transcripts in colon carcinoma. PMID: 9416836 |
Ref: Alteration of signal-transducing molecules in tumor-infiltrating lymphocytes and peripheral blood T lymphocytes from human colorectal carcinoma patients. PMID: 9490199 Ref: Adjuvant adoptive immunotherapy with tumour-infiltrating lymphocytes and modulated doses of interleukin-2 in 22 patients with melanoma, colorectal and renal cancer, after radical metastasectomy, and in 12 advanced patients. PMID: 9671141 Ref: Signal transduction abnormalities in T lymphocytes from patients with advanced renal carcinoma: clinical relevance and effects of cytokine therapy. PMID: 9796963 |
Ref: Carrier design: new generation of polycationic branched polypeptides containing OH groups with prolonged blood survival and diminished in vitro cytotoxicity. PMID: 10502343 |
Ref: Biochemical and cellular effects of c-Src kinase-selective pyrido[2, 3-d]pyrimidine tyrosine kinase inhibitors. PMID: 10974196 Ref: Preclinical oral antitumor activity of BMS-185660, a paclitaxel derivative. PMID: 11021743 |
Ref: Restored T-cell activation mechanisms in human tumour-infiltrating lymphocytes from melanomas and colorectal carcinomas after exposure to interleukin-2. PMID: 12610520 |
Ref: Src family kinase members have a common response to histone deacetylase inhibitors in human colon cancer cells. PMID: 16094635 |
Ref: Tyrosine phosphorylation of netrin receptors in netrin-1 signaling. PMID: 18253061 Ref: Odin (ANKS1A) is a Src family kinase target in colorectal cancer cells. PMID: 18844995 |
Ref: Prediction of liver metastasis after colorectal cancer using reverse transcription-polymerase chain reaction analysis of 10 genes. PMID: 20570135 Ref: Conditional inactivation of MLH1 in thymic and naive T-cells in mice leads to a limited incidence of lymphoblastic T-cell lymphomas. PMID: 20858091 |
Ref: Preclinical investigation of tolerance and antitumour activity of new fluorodeoxyglucose-coupled chlorambucil alkylating agents. PMID: 20033262 Ref: Inhibition of SRC family kinases and receptor tyrosine kinases by dasatinib: possible combinations in solid tumors. PMID: 21670084 |
Ref: Proteomic Features of Colorectal Cancer Identify Tumor Subtypes Independent of Oncogenic Mutations and Independently Predict Relapse-Free Survival. PMID: 28936799 |
Ref: Potent suppression of both spontaneous and carcinogen-induced colitis-associated colorectal cancer in mice by dietary celastrol supplementation. PMID: 29069290 Ref: Potential biomarkers for the early diagnosis of colorectal adenocarcinoma - transcriptomic analysis of four clinical stages. PMID: 29562499 |