Primary Site >> Colorectal Cancer

Gene >> LAG3

Journal: Mucosal Immunol. 2014 Mar;7(2):428-39.
Title: Highly prevalent colorectal cancer-infiltrating LAP(+) Foxp3(-) T cells exhibit more potent immunosuppressive activity than Foxp3(+) regulatory T cells.
Author: Scurr, M|Ladell, K|Besneux, M|Christian, A|Hockey, T|Smart, K|Bridgeman, H|Hargest, R|Phillips, S|Davies, M|Price, D|Gallimore, A|Godkin, A
PMID: 24064667
Journal: Med Oncol. 2014 Aug;31(8):82.
Title: The effect of immune microenvironment on the progression and prognosis of colorectal cancer.
Author: Chen, Jinxiang|Chen, Zihua
PMID: 25034363
Journal: Oncoimmunology. 2015 Apr 2;4(3):e976052.
Title: An immunogenomic stratification of colorectal cancer: Implications for development of targeted immunotherapy.
Author: Lal, Neeraj|Beggs, Andrew D|Willcox, Benjamin E|Middleton, Gary W
PMID: 25949894
Journal: Oncoimmunology. 2015 Mar 19;4(6):e1008355.
Title: Tumor-infiltrating plasmacytoid dendritic cells promote immunosuppression by Tr1 cells in human liver tumors.
Author: Pedroza-Gonzalez, Alexander|Zhou, Guoying|Vargas-Mendez, Ernesto|Boor, Patrick Pc|Mancham, Shanta|Verhoef, Cornelis|Polak, Wojciech G|Grunhagen, Dirk|Pan, Qiuwei|Janssen, Harry LA|Garcia-Romo, Gina S|Biermann, Katharina|Tjwa, Eric Ttl|IJzermans, Jan Nm|Kw
PMID: 26155417
Journal: J Cancer Res Clin Oncol. 2016 Aug;142(8):1775-80.
Title: Prognostic relevance of genetic variants involved in immune checkpoints in patients with colorectal cancer.
Author: Yoon, Shinkyo|Kang, Byung Woog|Park, Su Yeon|Kim, Hye Jin|Park, Jun Seok|Choi, Gyu Seog|Kim, Jong Gwang
PMID: 27339628
Journal: J Cancer Res Clin Oncol. 2018 Jun;144(6):1005-1014.
Title: CD274, LAG3, and IDO1 expressions in tumor-infiltrating immune cells as prognostic biomarker for patients with MSI-high colon cancer.
Author: Lee, Soo Jung|Jun, Sun-Young|Lee, In Hee|Kang, Byung Woog|Park, Su Yeon|Kim, Hye Jin|Park, Jun Seok|Choi, Gyu-Seog|Yoon, Ghilsuk|Kim, Jong Gwang
PMID: 29520442
Journal: Hum Immunol. 2018 Jun;79(6):446-452.
Title: CD8(+)CXCR5(+) T cells in tumor-draining lymph nodes are highly activated and predict better prognosis in colorectal cancer.
Author: E, Jifu|Yan, Feihu|Kang, Zhengchun|Zhu, Liangliang|Xing, Junjie|Yu, Enda
PMID: 29544815
Journal: JAMA Oncol. 2018 Aug 1;4(8):1085-1092.
Title: Immune Profiling of Premalignant Lesions in Patients With Lynch Syndrome.
Author: Chang, Kyle|Taggart, Melissa W|Reyes-Uribe, Laura|Borras, Ester|Riquelme, Erick|Barnett, Reagan M|Leoni, Guido|San Lucas, F Anthony|Catanese, Maria T|Mori, Federica|Diodoro, Maria G|You, Y Nancy|Hawk, Ernest T|Roszik, Jason|Scheet, Paul|Kopetz, Scott|Nico
PMID: 29710228
Journal: Ann Surg Oncol. 2018 Aug;25(8):2323-2331.
Title: Cytolytic Activity Score to Assess Anticancer Immunity in Colorectal Cancer.
Author: Narayanan, Sumana|Kawaguchi, Tsutomu|Yan, Li|Peng, Xuan|Qi, Qianya|Takabe, Kazuaki
PMID: 29770915
Journal: Ann Surg Treat Res. 2018 Jun;94(6):312-321.
Title: Diagnostic value of peripheral blood immune profiling in colorectal cancer.
Author: Choi, Joungbum|Maeng, Hyung Gun|Lee, Su Jin|Kim, Young Joo|Kim, Da Woon|Lee, Ha Na|Namgung, Ji Hyeon|Oh, Hyun-Mee|Kim, Tae Joo|Jeong, Ji Eun|Park, Sang Jean|Choi, Yong Man|Kang, Yong Won|Yoon, Seo Gue|Lee, Jong Kyun
PMID: 29854709
Journal: Oncoimmunology. 2018 Apr 25;7(7):e1448332.
Title: Blockade of LAG3 enhances responses of tumor-infiltrating T cells in mismatch repair-proficient liver metastases of colorectal cancer.
Author: Zhou, Guoying|Noordam, Lisanne|Sprengers, Dave|Doukas, Michail|Boor, Patrick P C|van Beek, Adriaan A|Erkens, Remco|Mancham, Shanta|Grunhagen, Dirk|Menon, Anand G|Lange, Johan F|Burger, Pim J W A|Brandt, Alexandra|Galjart, Boris|Verhoef, Cornelis|Kwekkeboo
PMID: 29900067
Journal: Clin Exp Pharmacol Physiol. 2018 Oct;45(10):1002-1009.
Title: Co-expression of LAG3 and TIM3 identifies a potent Treg population that suppresses macrophage functions in colorectal cancer patients.
Author: Ma, Qiang|Liu, Junning|Wu, Guoliang|Teng, Mujian|Wang, Shaoxuan|Cui, Meng|Li, Yuantao
PMID: 29905955
Journal: Cancer Manag Res. 2018 Sep 17;10:3569-3577.
Title: Low tumor purity is associated with poor prognosis, heavy mutation burden, and intense immune phenotype in colon cancer.
Author: Mao, Yihao|Feng, Qingyang|Zheng, Peng|Yang, Liangliang|Liu, Tianyu|Xu, Yuqiu|Zhu, Dexiang|Chang, Wenju|Ji, Meiling|Ren, Li|Wei, Ye|He, Guodong|Xu, Jianmin
PMID: 30271205
Journal: Oncol Rep. 2018 Sep 26.
Title: Antitumor effects of the silencing of programmed cell death ligand 1 in colorectal cancer via immunoregulation.
Author: Chen, Yilin|Huang, Ying|Lu, Xingrong|Wang, Gaoxiong|Chi, Pan
PMID: 30272332