Primary Site >> Colorectal Cancer
Gene >> LAG3
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Ref: Highly prevalent colorectal cancer-infiltrating LAP(+) Foxp3(-) T cells exhibit more potent immunosuppressive activity than Foxp3(+) regulatory T cells. PMID: 24064667 Ref: The effect of immune microenvironment on the progression and prognosis of colorectal cancer. PMID: 25034363 |
Ref: An immunogenomic stratification of colorectal cancer: Implications for development of targeted immunotherapy. PMID: 25949894 Ref: Tumor-infiltrating plasmacytoid dendritic cells promote immunosuppression by Tr1 cells in human liver tumors. PMID: 26155417 |
Ref: Prognostic relevance of genetic variants involved in immune checkpoints in patients with colorectal cancer. PMID: 27339628 |
Ref: CD274, LAG3, and IDO1 expressions in tumor-infiltrating immune cells as prognostic biomarker for patients with MSI-high colon cancer. PMID: 29520442 Ref: CD8(+)CXCR5(+) T cells in tumor-draining lymph nodes are highly activated and predict better prognosis in colorectal cancer. PMID: 29544815 Ref: Immune Profiling of Premalignant Lesions in Patients With Lynch Syndrome. PMID: 29710228 Ref: Cytolytic Activity Score to Assess Anticancer Immunity in Colorectal Cancer. PMID: 29770915 Ref: Diagnostic value of peripheral blood immune profiling in colorectal cancer. PMID: 29854709 Ref: Blockade of LAG3 enhances responses of tumor-infiltrating T cells in mismatch repair-proficient liver metastases of colorectal cancer. PMID: 29900067 Ref: Co-expression of LAG3 and TIM3 identifies a potent Treg population that suppresses macrophage functions in colorectal cancer patients. PMID: 29905955 Ref: Low tumor purity is associated with poor prognosis, heavy mutation burden, and intense immune phenotype in colon cancer. PMID: 30271205 Ref: Antitumor effects of the silencing of programmed cell death ligand 1 in colorectal cancer via immunoregulation. PMID: 30272332 |