Literatures

Primary Site >> Liver Cancer

Gene >> KRAS

1.
Journal:	Somat Cell Mol Genet. 1985 Jan;11(1):93-7.
Title:	Assignment of three rat cellular RAS oncogenes to chromosomes 1, 4, and X.
Author:	Szpirer, J\|Defeo-Jones, D\|Ellis, R W\|Levan, G\|Szpirer, C
PMID:	3856333

2.
Journal:	Am J Clin Pathol. 1993 Dec;100(6):686-9.
Title:	Mutation analysis of K-ras oncogenes in gastroenterologic cancers by the amplified created restriction sites method.
Author:	Lin, S Y\|Chen, P H\|Wang, C K\|Liu, J D\|Siauw, C P\|Chen, Y J\|Yang, M J\|Liu, M H\|Chen, T C\|Chang, J G
PMID:	8249918

3.
Journal:	Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1996 Apr;18(2):95-8.
Title:	[Detection of c-Ki-ras oncogene codon 12 point mutations in lung carcinoma, gastric carcinoma and hepatic carcinoma].
Author:	Cui, Q\|Wang, Z\|Chen, J\|Liu, T
PMID:	9208596

4.
Journal:	Br J Cancer. 1997;76(8):1001-10.
Title:	Manumycin and gliotoxin derivative KT7595 block Ras farnesylation and cell growth but do not disturb lamin farnesylation and localization in human tumour cells.
Author:	Nagase, T\|Kawata, S\|Tamura, S\|Matsuda, Y\|Inui, Y\|Yamasaki, E\|Ishiguro, H\|Ito, T\|Miyagawa, J\|Mitsui, H\|Yamamoto, K\|Kinoshita, M\|Matsuzawa, Y
PMID:	9376258

5.
Journal:	Am J Clin Pathol. 1998 Jun;109(6):704-11.
Title:	Detection of K-ras point mutations in the supernatants of peritoneal and pleural effusions for diagnosis complementary to cytologic examination.
Author:	Yamashita, K\|Kuba, T\|Shinoda, H\|Takahashi, E\|Okayasu, I
PMID:	9620027

6.
Journal:	Gut. 2003 May;52(5):706-12.
Title:	Mutations of the BRAF gene in cholangiocarcinoma but not in hepatocellular carcinoma.
Author:	Tannapfel, A\|Sommerer, F\|Benicke, M\|Katalinic, A\|Uhlmann, D\|Witzigmann, H\|Hauss, J\|Wittekind, C
PMID:	12692057

7.
Journal:	Cancer Res. 2006 Jan 1;66(1):242-7.
Title:	Mist1-KrasG12D knock-in mice develop mixed differentiation metastatic exocrine pancreatic carcinoma and hepatocellular carcinoma.
Author:	Tuveson, David A\|Zhu, Liqin\|Gopinathan, Aarthi\|Willis, Nicholas A\|Kachatrian, Leili\|Grochow, Rebecca\|Pin, Christopher L\|Mitin, Natalia Y\|Taparowsky, Elizabeth J\|Gimotty, Phyllis A\|Hruban, Ralph H\|Jacks, Tyler\|Konieczny, Stephen F
PMID:	16397237

8.
Journal:	Cancer Gene Ther. 2006 Aug;13(8):815-8.
Title:	Immunosuppression promotes reovirus therapy of colorectal liver metastases.
Author:	Smakman, N\|van der Bilt, J D W\|van den Wollenberg, D J M\|Hoeben, R C\|Borel Rinkes, I H M\|Kranenburg, O
PMID:	16543920

9.
Journal:	Int J Cancer. 2008 Dec 15;123(12):2735-40.
Title:	Organ-specific profiles of genetic changes in cancers caused by activation-induced cytidine deaminase expression.
Author:	Morisawa, Toshiyuki\|Marusawa, Hiroyuki\|Ueda, Yoshihide\|Iwai, Akio\|Okazaki, Il-mi\|Honjo, Tasuku\|Chiba, Tsutomu
PMID:	18781563

10.
Journal:	J Hematol Oncol. 2009 Feb 23;2:9.
Title:	Updates in Gastrointestinal Oncology - insights from the 2008 44th annual meeting of the American Society of Clinical Oncology.
Author:	Javle, Milind\|Hsueh, Chung-Tsen
PMID:	19236713

11.
Journal:	Gan To Kagaku Ryoho. 2009 Jun;36(6):1003-6.
Title:	[Two cases of KRAS wild-type unresectable or recurrent colorectal cancer effectively treated by cetuximab after progression of prior chemotherapy].
Author:	Yoda, Yusuke\|Yoshino, Takayuki\|Kadowaki, Shigenori\|Bando, Hideaki\|Okano, Susumu\|Fukushima, Hiraku\|Fuse, Nozomu\|Tahara, Makoto\|Doi, Toshihiko\|Ohtsu, Atsushi
PMID:	19542725

12.
Journal:	Cancer Genet Cytogenet. 2009 Dec;195(2):112-9.
Title:	Methylation profiling of tumor suppressor genes and oncogenes in hepatitis virus-related hepatocellular carcinoma in northern India.
Author:	Kiran, Manjula\|Chawla, Yogesh K\|Kaur, Jyotdeep
PMID:	19963110

13.
Journal:	Ther Apher Dial. 2010 Apr;14(2):222-5.
Title:	Fulminant plasmapheresis-refractory thrombotic microangiopathy associated with advanced gastric cancer.
Author:	Vasko, Radovan\|Koziolek, Michael\|Fuzesi, Laszlo\|Konig, Fatima\|Strutz, Frank\|Muller, Gerhard Anton
PMID:	20438546

14.
Journal:	BMC Cancer. 2010 Oct 6;10:530.
Title:	Genetic and epigenetic characteristics of human multiple hepatocellular carcinoma.
Author:	Taniguchi, Kazuya\|Yamada, Terumasa\|Sasaki, Yo\|Kato, Kikuya
PMID:	20923573

15.
Journal:	Br J Cancer. 2011 Mar 15;104(6):1020-6.
Title:	KRAS mutation analysis: a comparison between primary tumours and matched liver metastases in 305 colorectal cancer patients.
Author:	Knijn, N\|Mekenkamp, L J M\|Klomp, M\|Vink-Borger, M E\|Tol, J\|Teerenstra, S\|Meijer, J W R\|Tebar, M\|Riemersma, S\|van Krieken, J H J M\|Punt, C J A\|Nagtegaal, I D
PMID:	21364579

16.
Journal:	Clin Cancer Res. 2011 Jun 1;17(11):3551-7.
Title:	Detection of tumor DNA at the margins of colorectal cancer liver metastasis.
Author:	Holdhoff, Matthias\|Schmidt, Kerstin\|Diehl, Frank\|Aggrawal, Nishant\|Angenendt, Philipp\|Romans, Katharine\|Edelstein, Daniel L\|Torbenson, Michael\|Kinzler, Kenneth W\|Vogelstein, Bert\|Choti, Michael A\|Diaz, Luis A Jr
PMID:	21531819

17.
Journal:	Semin Liver Dis. 2011 May;31(2):173-87.
Title:	Genetics of hepatobiliary carcinogenesis.
Author:	Nault, Jean-Charles\|Zucman-Rossi, Jessica
PMID:	21538283

18.
Journal:	Br J Cancer. 2011 Jul 12;105(2):281-7.
Title:	Molecular alterations associated with liver metastases development in colorectal cancer patients.
Author:	Bruin, S C\|He, Y\|Mikolajewska-Hanclich, I\|Liefers, G-J\|Klijn, C\|Vincent, A\|Verwaal, V J\|de Groot, K A\|Morreau, H\|van Velthuysen, M-L F\|Tollenaar, R A E M\|van 't Veer, L J
PMID:	21673680

19.
Journal:	Pathobiology. 2011;78(2):76-89.
Title:	Changing pathology with changing drugs: tumors of the gastrointestinal tract.
Author:	Cervera, Pascale\|Flejou, Jean-Francois
PMID:	21677471

20.
Journal:	Dis Model Mech. 2011 Nov;4(6):801-13.
Title:	A high level of liver-specific expression of oncogenic Kras(V12) drives robust liver tumorigenesis in transgenic zebrafish.
Author:	Nguyen, Anh Tuan\|Emelyanov, Alexander\|Koh, Chor Hui Vivien\|Spitsbergen, Jan M\|Lam, Siew Hong\|Mathavan, Sinnakaruppan\|Parinov, Serguei\|Gong, Zhiyuan
PMID:	21729876

21.
Journal:	Neoplasia. 2011 Oct;13(10):931-46.
Title:	Hepatic carcinoma-associated fibroblasts promote an adaptative response in colorectal cancer cells that inhibit proliferation and apoptosis: nonresistant cells die by nonapoptotic cell death.
Author:	Berdiel-Acer, Mireia\|Bohem, Monika E\|Lopez-Doriga, Adriana\|Vidal, August\|Salazar, Ramon\|Martinez-Iniesta, Maria\|Santos, Cristina\|Sanjuan, Xavier\|Villanueva, Alberto\|Mollevi, David G
PMID:	22028619

22.
Journal:	Dis Model Mech. 2012 Jan;5(1):63-72.
Title:	An inducible kras(V12) transgenic zebrafish model for liver tumorigenesis and chemical drug screening.
Author:	Nguyen, Anh Tuan\|Emelyanov, Alexander\|Koh, Chor Hui Vivien\|Spitsbergen, Jan M\|Parinov, Serguei\|Gong, Zhiyuan
PMID:	21903676

23.
Journal:	Gastroenterology. 2012 Apr;142(4):1021-1031.e15.
Title:	Genomic and genetic characterization of cholangiocarcinoma identifies therapeutic targets for tyrosine kinase inhibitors.
Author:	Andersen, Jesper B\|Spee, Bart\|Blechacz, Boris R\|Avital, Itzhak\|Komuta, Mina\|Barbour, Andrew\|Conner, Elizabeth A\|Gillen, Matthew C\|Roskams, Tania\|Roberts, Lewis R\|Factor, Valentina M\|Thorgeirsson, Snorri S
PMID:	22178589

24.
Journal:	Oncologist. 2012;17(1):13.
Title:	Phase II trial of erlotinib and docetaxel in advanced and refractory hepatocellular and biliary cancers: Hoosier Oncology Group GI06-101.
Author:	Chiorean, E Gabriela\|Ramasubbaiah, Rashmi\|Yu, Menggang\|Picus, Joel\|Bufill, Jose A\|Tong, Yan\|Coleman, Nicki\|Johnston, Erica L\|Currie, Colleen\|Loehrer, Patrick J
PMID:	22210086

25.
Journal:	Cancer Res. 2012 Mar 15;72(6):1557-67.
Title:	Kras(G12D) and p53 mutation cause primary intrahepatic cholangiocarcinoma.
Author:	O'Dell, Michael R\|Huang, Jing Li\|Whitney-Miller, Christa L\|Deshpande, Vikram\|Rothberg, Paul\|Grose, Valerie\|Rossi, Randall M\|Zhu, Andrew X\|Land, Hartmut\|Bardeesy, Nabeel\|Hezel, Aram F
PMID:	22266220

26.
Journal:	Clin Cancer Res. 2012 Mar 15;18(6):1696-703.
Title:	Relationship between 18F-fluorodeoxyglucose accumulation and KRAS/BRAF mutations in colorectal cancer.
Author:	Kawada, Kenji\|Nakamoto, Yuji\|Kawada, Mayumi\|Hida, Koya\|Matsumoto, Takuya\|Murakami, Teppei\|Hasegawa, Suguru\|Togashi, Kaori\|Sakai, Yoshiharu
PMID:	22282467

27.
Journal:	BMC Cancer. 2012 Mar 13;12:88.
Title:	Amphiregulin and Epiregulin mRNA expression in primary colorectal cancer and corresponding liver metastases.
Author:	Kuramochi, Hidekazu\|Nakajima, Go\|Kaneko, Yuka\|Nakamura, Ayako\|Inoue, Yuji\|Yamamoto, Masakazu\|Hayashi, Kazuhiko
PMID:	22409860

28.
Journal:	J Exp Clin Cancer Res. 2012 Mar 23;31:26.
Title:	Osteopontin induces growth of metastatic tumors in a preclinical model of non-small lung cancer.
Author:	Shojaei, Farbod\|Scott, Nathan\|Kang, Xiaolin\|Lappin, Patrick B\|Fitzgerald, Amanda A\|Karlicek, Shannon\|Simmons, Brett H\|Wu, Aidong\|Lee, Joseph H\|Bergqvist, Simon\|Kraynov, Eugenia
PMID:	22444159

29.
Journal:	Anticancer Res. 2012 Apr;32(4):1457-61.
Title:	Comparison of the chemosensitivity of the primary lesion and a pancreatic metastasis of colon cancer: a case report.
Author:	Tamagawa, Hiroshi\|Miyagi, Yohei\|Numata, Masakatsu\|Yamamoto, Naoto\|Shiozawa, Manabu\|Morinaga, Soichiro\|Sekiyama, Akiko\|Sekiguchi, Hironobu\|Sakuma, Yuji\|Kameda, Yoichi\|Akaike, Makoto\|Masuda, Munetaka\|Imada, Toshio
PMID:	22493386

30.
Journal:	Br J Surg. 2012 Nov;99(11):1575-82.
Title:	KRAS status and outcome of liver resection after neoadjuvant chemotherapy including bevacizumab.
Author:	Stremitzer, S\|Stift, J\|Gruenberger, B\|Tamandl, D\|Aschacher, T\|Wolf, B\|Wrba, F\|Gruenberger, T
PMID:	23027075

31.
Journal:	J Hepatobiliary Pancreat Sci. 2013 Feb;20(2):223-33.
Title:	Poor prognosis of KRAS or BRAF mutant colorectal liver metastasis without microsatellite instability.
Author:	Umeda, Yuzo\|Nagasaka, Takeshi\|Mori, Yoshiko\|Sadamori, Hiroshi\|Sun, Dong-Sheng\|Shinoura, Susumu\|Yoshida, Ryuich\|Satoh, Daisuke\|Nobuoka, Daisuke\|Utsumi, Masashi\|Yoshida, Kazuhiro\|Yagi, Takahito\|Fujiwara, Toshiyoshi
PMID:	23010994

32.
Journal:	Gastroenterology. 2013 Apr;144(4):829-40.
Title:	Integrative molecular analysis of intrahepatic cholangiocarcinoma reveals 2 classes that have different outcomes.
Author:	Sia, Daniela\|Hoshida, Yujin\|Villanueva, Augusto\|Roayaie, Sasan\|Ferrer, Joana\|Tabak, Barbara\|Peix, Judit\|Sole, Manel\|Tovar, Victoria\|Alsinet, Clara\|Cornella, Helena\|Klotzle, Brandy\|Fan, Jian-Bing\|Cotsoglou, Christian\|Thung, Swan N\|Fuster, Josep\|Waxman, Sam
PMID:	23295441

33.
Journal:	Oncogene. 2013 Oct 10;32(41):4861-70.
Title:	Intrahepatic cholangiocarcinoma: pathogenesis and rationale for molecular therapies.
Author:	Sia, D\|Tovar, V\|Moeini, A\|Llovet, J M
PMID:	23318457

34.
Journal:	Jpn J Clin Oncol. 2013 May;43(5):579-82.
Title:	MicroRNAs in Cancer: the 22nd Hiroshima Cancer Seminar/the 4th Japanese Association for RNA Interference Joint International Symposium, 30 August 2012, Grand Prince Hotel Hiroshima.
Author:	Tahara, Hidetoshi\|Kay, Mark A\|Yasui, Wataru\|Tahara, Eiichi
PMID:	23487440

35.
Journal:	Hepatology. 2013 Dec;58(6):1964-76.
Title:	Hepatocyte nuclear factor-4alpha reverses malignancy of hepatocellular carcinoma through regulating miR-134 in the DLK1-DIO3 region.
Author:	Yin, Chuan\|Wang, Pei-Qin\|Xu, Wen-Ping\|Yang, Yuan\|Zhang, Qing\|Ning, Bei-Fang\|Zhang, Ping-Ping\|Zhou, Wei-Ping\|Xie, Wei-Fen\|Chen, Wan-Sheng\|Zhang, Xin
PMID:	23775631

36.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2013 Aug;16(8):718-20.
Title:	[Consideration of therapy for colorectal cancer with synchronous unresectable liver metastasis].
Author:	Zhu, De-xiang\|Ren, Li\|Xu, Jian-min
PMID:	23980038

37.
Journal:	PLoS One. 2013 Jun 3;8(6):e65117.
Title:	Prognostic significance of C-reactive protein polymorphism and KRAS/BRAF in synchronous liver metastasis from colorectal cancer.
Author:	Huang, Chi-Jung\|Teng, Hao-Wei\|Chien, Chih-Cheng\|Lin, Jen-Kou\|Yang, Shung-Haur
PMID:	23755178

38.
Journal:	Oncogene. 2014 Jun 5;33(23):2949-55.
Title:	Discovery of colorectal cancer PIK3CA mutation as potential predictive biomarker: power and promise of molecular pathological epidemiology.
Author:	Ogino, S\|Lochhead, P\|Giovannucci, E\|Meyerhardt, J A\|Fuchs, C S\|Chan, A T
PMID:	23792451

39.
Journal:	Oncogene. 2014 May 22;33(21):2717-27.
Title:	Crosstalk of Ras and Rho: activation of RhoA abates Kras-induced liver tumorigenesis in transgenic zebrafish models.
Author:	Chew, T W\|Liu, X J\|Liu, L\|Spitsbergen, J M\|Gong, Z\|Low, B C
PMID:	23812423

40.
Journal:	Hepatology. 2014 Apr;59(4):1427-34.
Title:	Fibroblast growth factor receptor 2 tyrosine kinase fusions define a unique molecular subtype of cholangiocarcinoma.
Author:	Arai, Yasuhito\|Totoki, Yasushi\|Hosoda, Fumie\|Shirota, Tomoki\|Hama, Natsuko\|Nakamura, Hiromi\|Ojima, Hidenori\|Furuta, Koh\|Shimada, Kazuaki\|Okusaka, Takuji\|Kosuge, Tomoo\|Shibata, Tatsuhiro
PMID:	24122810

41.
Journal:	Oncogene. 2014 Oct 23;33(43):5133-8.
Title:	Synergistic function of Kras mutation and HBx in initiation and progression of hepatocellular carcinoma in mice.
Author:	Ye, H\|Zhang, C\|Wang, B-J\|Tan, X-H\|Zhang, W-P\|Teng, Y\|Yang, X
PMID:	24213574

42.
Journal:	Oncologist. 2014 Mar;19(3):235-42.
Title:	New routes to targeted therapy of intrahepatic cholangiocarcinomas revealed by next-generation sequencing.
Author:	Ross, Jeffrey S\|Wang, Kai\|Gay, Laurie\|Al-Rohil, Rami\|Rand, Janne V\|Jones, David M\|Lee, Hwa J\|Sheehan, Christine E\|Otto, Geoff A\|Palmer, Gary\|Yelensky, Roman\|Lipson, Doron\|Morosini, Deborah\|Hawryluk, Matthew\|Catenacci, Daniel V T\|Miller, Vincent A\|Churi, C
PMID:	24563076

43.
Journal:	PLoS One. 2014 Feb 19;9(2):e89388.
Title:	FBXW7 mutations in patients with advanced cancers: clinical and molecular characteristics and outcomes with mTOR inhibitors.
Author:	Jardim, Denis L\|Wheler, Jennifer J\|Hess, Kenneth\|Tsimberidou, Apostolia M\|Zinner, Ralph\|Janku, Filip\|Subbiah, Vivek\|Naing, Aung\|Piha-Paul, Sarina A\|Westin, Shannon N\|Roy-Chowdhuri, Sinchita\|Meric-Bernstam, Funda\|Hong, David S
PMID:	24586741

44.
Journal:	PLoS One. 2014 Mar 14;9(3):e91179.
Title:	Xmrk, kras and myc transgenic zebrafish liver cancer models share molecular signatures with subsets of human hepatocellular carcinoma.
Author:	Zheng, Weiling\|Li, Zhen\|Nguyen, Anh Tuan\|Li, Caixia\|Emelyanov, Alexander\|Gong, Zhiyuan
PMID:	24633177

45.
Journal:	PLoS One. 2014 May 5;9(5):e95307.
Title:	Transcriptomic characterization of hepatocellular carcinoma with CTNNB1 mutation.
Author:	Ding, Xiao\|Yang, Yuan\|Han, Baoda\|Du, Chengzhi\|Xu, Naiqing\|Huang, Huanwei\|Cai, Tao\|Zhang, Aiqun\|Han, Ze-Guang\|Zhou, Weiping\|Chen, Liang
PMID:	24798046

46.
Journal:	J Clin Invest. 2014 Jul;124(7):3172-86.
Title:	Four individually druggable MET hotspots mediate HGF-driven tumor progression.
Author:	Basilico, Cristina\|Hultberg, Anna\|Blanchetot, Christophe\|de Jonge, Natalie\|Festjens, Els\|Hanssens, Valerie\|Osepa, Sjudry-Ilona\|De Boeck, Gitte\|Mira, Alessia\|Cazzanti, Manuela\|Morello, Virginia\|Dreier, Torsten\|Saunders, Michael\|de Haard, Hans\|Michieli, Pao
PMID:	24865428

47.
Journal:	Nat Cell Biol. 2014 Jul;16(7):685-94.
Title:	Colon cancer cells colonize the lung from established liver metastases through p38 MAPK signalling and PTHLH.
Author:	Urosevic, Jelena\|Garcia-Albeniz, Xabier\|Planet, Evarist\|Real, Sebastian\|Cespedes, Maria Virtudes\|Guiu, Marc\|Fernandez, Esther\|Bellmunt, Anna\|Gawrzak, Sylwia\|Pavlovic, Milica\|Mangues, Ramon\|Dolado, Ignacio\|Barriga, Francisco M\|Nadal, Cristina\|Kemeny, Nancy
PMID:	24880666

48.
Journal:	Nature. 2014 Sep 4;513(7516):110-4.
Title:	Mutant IDH inhibits HNF-4alpha to block hepatocyte differentiation and promote biliary cancer.
Author:	Saha, Supriya K\|Parachoniak, Christine A\|Ghanta, Krishna S\|Fitamant, Julien\|Ross, Kenneth N\|Najem, Mortada S\|Gurumurthy, Sushma\|Akbay, Esra A\|Sia, Daniela\|Cornella, Helena\|Miltiadous, Oriana\|Walesky, Chad\|Deshpande, Vikram\|Zhu, Andrew X\|Hezel, Aram F\|Yen,
PMID:	25043045

49.
Journal:	Oncol Lett. 2014 Sep;8(3):1249-1254.
Title:	Mutation analysis of key genes in RAS/RAF and PI3K/PTEN pathways in Chinese patients with hepatocellular carcinoma.
Author:	Hou, Wenmin\|Liu, Jibin\|Chen, Peizhan\|Wang, Hui\|Ye, Bang-Ce\|Qiang, Fulin
PMID:	25120700

50.
Journal:	PLoS One. 2014 Aug 15;9(8):e104979.
Title:	Reporting tumor molecular heterogeneity in histopathological diagnosis.
Author:	Mafficini, Andrea\|Amato, Eliana\|Fassan, Matteo\|Simbolo, Michele\|Antonello, Davide\|Vicentini, Caterina\|Scardoni, Maria\|Bersani, Samantha\|Gottardi, Marisa\|Rusev, Borislav\|Malpeli, Giorgio\|Corbo, Vincenzo\|Barbi, Stefano\|Sikora, Katarzyna O\|Lawlor, Rita T\|Tor
PMID:	25127237

51.
Journal:	Health Technol Assess. 2014 Oct;18(62):1-132.
Title:	KRAS mutation testing of tumours in adults with metastatic colorectal cancer: a systematic review and cost-effectiveness analysis.
Author:	Westwood, Marie\|van Asselt, Thea\|Ramaekers, Bram\|Whiting, Penny\|Joore, Manuela\|Armstrong, Nigel\|Noake, Caro\|Ross, Janine\|Severens, Johan\|Kleijnen, Jos
PMID:	25314637

52.
Journal:	Int Surg. 2014 Nov-Dec;99(6):795-801.
Title:	Conversion Therapy Using mFOLFOX6 With Panitumumab for Unresectable Liver Metastases From Multiple Colorectal Cancers With Familial Adenomatous Polyposis.
Author:	Toiyama, Yuji\|Inoue, Yasuhiro\|Kitajima, Takahito\|Okigami, Masato\|Kawamura, Mikio\|Kawamoto, Aya\|Okugawa, Yoshinaga\|Hiro, Jyunichiro\|Tanaka, Koji\|Mohri, Yasuhiko\|Kusunoki, Masato
PMID:	25437589

53.
Journal:	J Hepatobiliary Pancreat Sci. 2015 Feb;22(2):114-23.
Title:	Molecular diagnosis of intrahepatic cholangiocarcinoma.
Author:	Haga, Hiroaki\|Patel, Tushar
PMID:	25267595

54.
Journal:	Nat Commun. 2015 Jan 22;6:6087.
Title:	Massive parallel sequencing uncovers actionable FGFR2-PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma.
Author:	Sia, Daniela\|Losic, Bojan\|Moeini, Agrin\|Cabellos, Laia\|Hao, Ke\|Revill, Kate\|Bonal, Dennis\|Miltiadous, Oriana\|Zhang, Zhongyang\|Hoshida, Yujin\|Cornella, Helena\|Castillo-Martin, Mireia\|Pinyol, Roser\|Kasai, Yumi\|Roayaie, Sasan\|Thung, Swan N\|Fuster, Josep\|Schw
PMID:	25608663

55.
Journal:	Sci Rep. 2015 Jan 27;5:8053.
Title:	Transgenic mouse model expressing P53(R172H), luciferase, EGFP, and KRAS(G12D) in a single open reading frame for live imaging of tumor.
Author:	Ju, Hye-Lim\|Calvisi, Diego F\|Moon, Hyuk\|Baek, Sinhwa\|Ribback, Silvia\|Dombrowski, Frank\|Cho, Kyung Joo\|Chung, Sook In\|Han, Kwang-Hyub\|Ro, Simon Weonsang
PMID:	25623590

56.
Journal:	Nat Commun. 2015 Jan 30;6:6120.
Title:	Whole-genome mutational landscape of liver cancers displaying biliary phenotype reveals hepatitis impact and molecular diversity.
Author:	Fujimoto, Akihiro\|Furuta, Mayuko\|Shiraishi, Yuichi\|Gotoh, Kunihito\|Kawakami, Yoshiiku\|Arihiro, Koji\|Nakamura, Toru\|Ueno, Masaki\|Ariizumi, Shun-ichi\|Nguyen, Ha Hai\|Shigemizu, Daichi\|Abe, Tetsuo\|Boroevich, Keith A\|Nakano, Kaoru\|Sasaki, Aya\|Kitada, Rina\|Maej
PMID:	25636086

57.
Journal:	Mol Cancer. 2015 Feb 3;14:18.
Title:	Oncogenic KRAS promotes malignant brain tumors in zebrafish.
Author:	Ju, Bensheng\|Chen, Wenbiao\|Orr, Brent A\|Spitsbergen, Jan M\|Jia, Sujuan\|Eden, Christopher J\|Henson, Hannah E\|Taylor, Michael R
PMID:	25644510

58.
Journal:	J Hepatol. 2015 Aug;63(2):420-8.
Title:	Stimulation of hepatocarcinogenesis by neutrophils upon induction of oncogenic kras expression in transgenic zebrafish.
Author:	Yan, Chuan\|Huo, Xiaojing\|Wang, Shu\|Feng, Yi\|Gong, Zhiyuan
PMID:	25828472

59.
Journal:	World J Gastrointest Oncol. 2015 Jun 15;7(6):47-54.
Title:	Locoregional therapy and systemic cetuximab to treat colorectal liver metastases.
Author:	Fiorentini, Giammaria\|Aliberti, Camillo\|Sarti, Donatella\|Coschiera, Paolo\|Tilli, Massimo\|Mulazzani, Luca\|Giordani, Paolo\|Graziano, Francesco\|Gonzalez, Alfonso Marques\|Marcos, Raul Garcia\|Mugnoz, Fernando Gomez\|Cantore, Maurizio\|Ricci, Stefano\|Catalano, Vi
PMID:	26090075

60.
Journal:	Mol Med Rep. 2015 Sep;12(3):4678-4682.
Title:	Targeted sequencing of cancer-associated genes in hepatocellular carcinoma using next generation sequencing.
Author:	Lu, Jianguo\|Yin, Jikai\|Dong, Rui\|Yang, Tao\|Yuan, Lijuan\|Zang, Li\|Xu, Cheng\|Peng, Bo\|Zhao, Jiangman\|Du, Xilin
PMID:	26096009

61.
Journal:	Chem Biol Interact. 2015 Dec 5;242:107-22.
Title:	Novel carbocyclic curcumin analog CUR3d modulates genes involved in multiple apoptosis pathways in human hepatocellular carcinoma cells.
Author:	Bhullar, Khushwant S\|Jha, Amitabh\|Rupasinghe, H P Vasantha
PMID:	26409325

62.
Journal:	Int J Clin Exp Pathol. 2015 Aug 1;8(8):8821-31. eCollection 2015.
Title:	Gene expression of IQGAPs and Ras families in an experimental mouse model for hepatocellular carcinoma: a mechanistic study of cancer progression.
Author:	Zoheir, Khairy M A\|Abd-Rabou, Ahmed A\|Harisa, Gamaleldin I\|Ashour, Abdelkader E\|Ahmad, Sheikh Fayaz\|Attia, Sabry M\|Bakheet, Saleh A\|Abdel-Hamied, Hala E\|Abd-Allah, Adel R\|Kumar, Ashok
PMID:	26464624

63.
Journal:	Genet Mol Res. 2015 Oct 30;14(4):14050-5.
Title:	An let-7 KRAS rs712 polymorphism increases hepatocellular carcinoma risk.
Author:	Xiong, D\|Song, Y P\|Xiong, W\|Liang, Y D
PMID:	26535719

64.
Journal:	Mol Clin Oncol. 2015 Nov;3(6):1275-1279.
Title:	Prevalence of K-Ras mutations in hepatocellular carcinoma: A Turkish Oncology Group pilot study.
Author:	Turhal, Nazim Serdar\|Savas, Berna\|Coskun, Oznur\|Bas, Emine\|Karabulut, Bulent\|Nart, Deniz\|Korkmaz, Taner\|Yavuzer, Dilek\|Demir, Gokhan\|Dogusoy, Gulen\|Artac, Mehmet
PMID:	26807232

65.
Journal:
Title:	Roles of E-cadherin in Hepatocarcinogenesis
Author:	Maeda, Shin\|Nakagawa, Hayato
PMID:	29787164

66.
Journal:	Oncogene. 2016 May 19;35(20):2547-61.
Title:	Stamping out RAF and MEK1/2 to inhibit the ERK1/2 pathway: an emerging threat to anticancer therapy.
Author:	Mandal, R\|Becker, S\|Strebhardt, K
PMID:	26364606

67.
Journal:	J Hepatol. 2016 Mar;64(3):618-27.
Title:	Hepatic expression of Sonic Hedgehog induces liver fibrosis and promotes hepatocarcinogenesis in a transgenic mouse model.
Author:	Chung, Sook In\|Moon, Hyuk\|Ju, Hye-Lim\|Cho, Kyung Joo\|Kim, Do Young\|Han, Kwang-Hyub\|Eun, Jung Woo\|Nam, Suk Woo\|Ribback, Silvia\|Dombrowski, Frank\|Calvisi, Diego F\|Ro, Simon Weonsang
PMID:	26471504

68.
Journal:	Ann Oncol. 2016 Feb;27(2):267-74.
Title:	Conversion to resection of liver metastases from colorectal cancer with hepatic artery infusion of combined chemotherapy and systemic cetuximab in multicenter trial OPTILIV.
Author:	Levi, F A\|Boige, V\|Hebbar, M\|Smith, D\|Lepere, C\|Focan, C\|Karaboue, A\|Guimbaud, R\|Carvalho, C\|Tumolo, S\|Innominato, P\|Ajavon, Y\|Truant, S\|Castaing, D\|De Baere, T\|Kunstlinger, F\|Bouchahda, M\|Afshar, M\|Rougier, P\|Adam, R\|Ducreux, M
PMID:	26578731

69.
Journal:	Clin Cancer Res. 2016 May 15;22(10):2368-76.
Title:	A Phase I Study of the Safety, Pharmacokinetics, and Pharmacodynamics of Combination Therapy with Refametinib plus Sorafenib in Patients with Advanced Cancer.
Author:	Adjei, Alex A\|Richards, Donald A\|El-Khoueiry, Anthony\|Braiteh, Fadi\|Becerra, Carlos H R\|Stephenson, Joe J Jr\|Hezel, Aram F\|Sherman, Morris\|Garbo, Lawrence\|Leffingwell, Diane P\|Iverson, Cory\|Miner, Jeffrey N\|Shen, Zancong\|Yeh, Li-Tain\|Gunawan, Sonny\|Wilson
PMID:	26644411

70.
Journal:	Crit Rev Oncol Hematol. 2016 Mar;99:150-7.
Title:	Can KRAS and BRAF mutations limit the benefit of liver resection in metastatic colorectal cancer patients? A systematic review and meta-analysis.
Author:	Passiglia, Francesco\|Bronte, Giuseppe\|Bazan, Viviana\|Galvano, Antonio\|Vincenzi, Bruno\|Russo, Antonio
PMID:	26775732

71.
Journal:	Sci Rep. 2016 Jan 21;6:19559.
Title:	Development of a conditional liver tumor model by mifepristone-inducible Cre recombination to control oncogenic kras V12 expression in transgenic zebrafish.
Author:	Nguyen, Anh Tuan\|Koh, Vivien\|Spitsbergen, Jan M\|Gong, Zhiyuan
PMID:	26790949

72.
Journal:	BMC Cancer. 2016 Feb 18;16:120.
Title:	The impact of KRAS mutations on prognosis in surgically resected colorectal cancer patients with liver and lung metastases: a retrospective analysis.
Author:	Kim, Hae Su\|Heo, Jin Seok\|Lee, Jeeyun\|Lee, Ji Yun\|Lee, Min-Young\|Lim, Sung Hee\|Lee, Woo Yong\|Kim, Seok Hyung\|Park, Yoon Ah\|Cho, Yong Beom\|Yun, Seong Hyeon\|Kim, Seung Tae\|Park, Joon Oh\|Lim, Ho Yeong\|Choi, Yong Soo\|Kwon, Woo Il\|Kim, Hee Cheol\|Park, Young Su
PMID:	26887348

73.
Journal:	Oncotarget. 2016 Apr 19;7(16):21825-39.
Title:	MicroRNA-543 suppresses colorectal cancer growth and metastasis by targeting KRAS, MTA1 and HMGA2.
Author:	Fan, Chuannan\|Lin, Yancheng\|Mao, Yubin\|Huang, Zhengjie\|Liu, Allan Yi\|Ma, Handong\|Yu, Donghong\|Maitikabili, Alaiyi\|Xiao, Hongjun\|Zhang, Chuankai\|Liu, Fan\|Luo, Qi\|Ouyang, Gaoliang
PMID:	26968810

74.
Journal:	Oncotarget. 2016 Apr 26;7(17):23825-36.
Title:	Two classes of intrahepatic cholangiocarcinoma defined by relative abundance of mutations and copy number alterations.
Author:	Kim, Young-Ho\|Hong, Eun-Kyung\|Kong, Sun-Young\|Han, Sung-Sik\|Kim, Seoung-Hoon\|Rhee, Je-Keun\|Hwang, Soo-Kyung\|Park, Sang-Jae\|Kim, Tae-Min
PMID:	27009864

75.
Journal:	Oncotarget. 2016 Jul 19;7(29):46750-46767.
Title:	The landscape of targeted therapies for cholangiocarcinoma: current status and emerging targets.
Author:	Chong, Dawn Q\|Zhu, Andrew X
PMID:	27102149

76.
Journal:	Sci Rep. 2016 May 4;6:24944.
Title:	Molecular targets of Chinese herbs: a clinical study of hepatoma based on network pharmacology.
Author:	Gao, Li\|Wang, Xiao-Dong\|Niu, Yang-Yang\|Duan, Dan-Dan\|Yang, Xue\|Hao, Jian\|Zhu, Cui-Hong\|Chen, Dan\|Wang, Ke-Xin\|Qin, Xue-Mei\|Wu, Xiong-Zhi
PMID:	27143508

77.
Journal:	Medicine (Baltimore). 2016 May;95(20):e3722.
Title:	Conversion Chemotherapy for Technically Unresectable Colorectal Liver Metastases: A Retrospective, STROBE-Compliant, Single-Center Study Comparing Chemotherapy Alone and Combination Chemotherapy With Cetuximab or Bevacizumab.
Author:	Basso, Michele\|Dadduzio, Vincenzo\|Ardito, Francesco\|Lombardi, Pasquale\|Strippoli, Antonia\|Vellone, Maria\|Orlandi, Armando\|Rossi, Sabrina\|Cerchiaro, Eleonora\|Cassano, Alessandra\|Giuliante, Felice\|Barone, Carlo
PMID:	27196492

78.
Journal:	Tumour Biol. 2016 Oct;37(10):13927-13939.
Title:	IQGAP1 gene silencing induces apoptosis and decreases the invasive capacity of human hepatocellular carcinoma cells.
Author:	Zoheir, Khairy Ma\|Abd-Rabou, Ahmed A\|Harisa, Gamaleldin I\|Kumar, Ashok\|Ahmad, Sheikh Fayaz\|Ansari, Mushtaq Ahmad\|Abd-Allah, Adel R
PMID:	27488117

79.
Journal:	Gastroenterology. 2016 Nov;151(5):1011-1024.e7.
Title:	Pancreatic Premalignant Lesions Secrete Tissue Inhibitor of Metalloproteinases-1, Which Activates Hepatic Stellate Cells Via CD63 Signaling to Create a Premetastatic Niche in the Liver.
Author:	Grunwald, Barbara\|Harant, Veronika\|Schaten, Susanne\|Fruhschutz, Monika\|Spallek, Ria\|Hochst, Bastian\|Stutzer, Katharina\|Berchtold, Sonja\|Erkan, Mert\|Prokopchuk, Olga\|Martignoni, Marc\|Esposito, Irene\|Heikenwalder, Mathias\|Gupta, Aayush\|Siveke, Jens\|Saftig,
PMID:	27506299

80.
Journal:	J Gastrointest Oncol. 2016 Aug;7(4):570-9.
Title:	A genetic database can be utilized to identify potential biomarkers for biphenotypic hepatocellular carcinoma-cholangiocarcinoma.
Author:	Mok, Shaffer R S\|Mohan, Sachin\|Grewal, Navjot\|Elfant, Adam B\|Judge, Thomas A
PMID:	27563447

81.
Journal:	Eur J Surg Oncol. 2016 Oct;42(10):1540-7.
Title:	FOLFIRI plus cetuximab in patients with liver-limited or non-liver-limited RAS wild-type metastatic colorectal cancer: A retrospective subgroup analysis of the CRYSTAL study.
Author:	Kohne, C-H\|Poston, G\|Folprecht, G\|Ciardiello, F\|Ronga, P\|Beier, F\|Van Cutsem, E
PMID:	27575968

82.
Journal:	Eur J Cancer. 2016 Nov;68:163-172.
Title:	Early tumour response as a survival predictor in previously- treated patients receiving triplet hepatic artery infusion and intravenous cetuximab for unresectable liver metastases from wild-type KRAS colorectal cancer.
Author:	Bouchahda, Mohamed\|Boige, Valerie\|Smith, Denis\|Karaboue, Abdoulaye\|Ducreux, Michel\|Hebbar, Mohamed\|Lepere, Celine\|Focan, Christian\|Guimbaud, Rosine\|Innominato, Pasquale\|Awad, Sameh\|Carvalho, Carlos\|Tumolo, Salvatore\|Truant, Stephanie\|De Baere, Thierry\|Cas
PMID:	27768923

83.
Journal:	Oncoimmunology. 2016 Nov 29;5(12):e1254313.
Title:	CXCR4-CXCL12-CXCR7, TLR2-TLR4, and PD-1/PD-L1 in colorectal cancer liver metastases from neoadjuvant-treated patients.
Author:	D'Alterio, Crescenzo\|Nasti, Guglielmo\|Polimeno, Marianeve\|Ottaiano, Alessandro\|Conson, Manuel\|Circelli, Luisa\|Botti, Giovanni\|Scognamiglio, Giosue\|Santagata, Sara\|De Divitiis, Chiara\|Nappi, Anna\|Napolitano, Maria\|Tatangelo, Fabiana\|Pacelli, Roberto\|Izzo,
PMID:	28123896

84.
Journal:	J Cancer Res Ther. 2016 Dec;12(Supplement):C205-C211.
Title:	The significance of transarterial chemoembolization combined with systemic chemotherapy for patients with KRAS wild-type unresectable metachronous colorectal carcinoma with liver metastases.
Author:	Yu, Qiming\|Zhang, Lusha\|Fan, Sunfu\|Huang, Ling\|Wang, Xinbao\|Xindun, Cai
PMID:	28230018

85.
Journal:	Abdom Radiol (NY). 2017 Feb;42(2):451-459.
Title:	Connecting cancer biology and clinical outcomes to imaging in KRAS mutant and wild-type colorectal cancer liver tumors following selective internal radiation therapy with yttrium-90.
Author:	Magnetta, Michael J\|Ghodadra, Anish\|Lahti, Steven J\|Xing, Minzhi\|Zhang, Di\|Kim, Hyun S
PMID:	27600383

86.
Journal:	Histopathology. 2017 Feb;70(3):423-434.
Title:	Mutational landscape of combined hepatocellular carcinoma and cholangiocarcinoma, and its clinicopathological significance.
Author:	Sasaki, Motoko\|Sato, Yasunori\|Nakanuma, Yasuni
PMID:	27634656

87.
Journal:	Clin Cancer Res. 2017 Mar 15;23(6):1607-1620.
Title:	Mutant p53 Together with TGFbeta Signaling Influence Organ-Specific Hematogenous Colonization Patterns of Pancreatic Cancer.
Author:	Zhong, Yi\|Macgregor-Das, Anne\|Saunders, Tyler\|Whittle, Martin C\|Makohon-Moore, Alvin\|Kohutek, Zachary A\|Poling, Justin\|Herbst, Brian T\|Javier, Breanna M\|Cope, Leslie\|Leach, Steven D\|Hingorani, Sunil R\|Iacobuzio-Donahue, Christine A
PMID:	27637888

88.
Journal:	Ann Surg Oncol. 2017 Feb;24(2):546-553.
Title:	The COMET Open-label Phase II Study of Neoadjuvant FOLFOX or XELOX Treatment Combined with Molecular Targeting Monoclonal Antibodies in Patients with Resectable Liver Metastasis of Colorectal Cancer.
Author:	Kataoka, Masato\|Kanda, Mitsuro\|Ishigure, Kiyoshi\|Matsuoka, Hiroshi\|Sato, Yusuke\|Takahashi, Takao\|Tanaka, Chihiro\|Deguchi, Tomohiro\|Shibata, Yoshihisa\|Sato, Mikinori\|Inagaki, Hitoshi\|Matsui, Takanori\|Kondo, Akinobu\|Takano, Nao\|Tanaka, Haruyoshi\|Sakamoto, J
PMID:	27638675

89.
Journal:	Oncol Rep. 2017 Jan;37(1):57-65.
Title:	Yttrium-90 radioembolization for colorectal cancer liver metastases in KRAS wild-type and mutant patients: Clinical and ccfDNA studies.
Author:	Janowski, E\|Timofeeva, O\|Chasovskikh, S\|Goldberg, M\|Kim, A\|Banovac, F\|Pang, D\|Dritschilo, A\|Unger, K
PMID:	28004119

90.
Journal:	Sci Rep. 2017 Jan 24;7:41280.
Title:	Males develop faster and more severe hepatocellular carcinoma than females in kras(V12) transgenic zebrafish.
Author:	Li, Yan\|Li, Hankun\|Spitsbergen, Jan M\|Gong, Zhiyuan
PMID:	28117409

91.
Journal:	Cancer Res. 2017 Mar 15;77(6):1395-1407.
Title:	Tumor-Associated Neutrophils and Macrophages Promote Gender Disparity in Hepatocellular Carcinoma in Zebrafish.
Author:	Yan, Chuan\|Yang, Qiqi\|Gong, Zhiyuan
PMID:	28202512

92.
Journal:	Cancer Sci. 2017 May;108(5):877-885.
Title:	Transcriptomic analyses of RNA-binding proteins reveal eIF3c promotes cell proliferation in hepatocellular carcinoma.
Author:	Li, Tangjian\|Li, Shengli\|Chen, Di\|Chen, Bing\|Yu, Tao\|Zhao, Fangyu\|Wang, Qifeng\|Yao, Ming\|Huang, Shenglin\|Chen, Zhiao\|He, Xianghuo
PMID:	28231410

93.
Journal:	Sci Rep. 2017 Apr 5;7:45796.
Title:	Chemical inhibition reveals differential requirements of signaling pathways in kras(V12)- and Myc-induced liver tumors in transgenic zebrafish.
Author:	Yan, Chuan\|Yang, Qiqi\|Huo, Xiaojing\|Li, Hankun\|Zhou, Li\|Gong, Zhiyuan
PMID:	28378824

94.
Journal:	J Cancer. 2017 Feb 25;8(5):730-736.
Title:	An investigation of the role of gene copy number variations in sorafenib sensitivity in metastatic hepatocellular carcinoma patients.
Author:	Lee, Ji Yun\|Hong, Mineui\|Lee, Jeeyun\|Lee, Sujin\|Kim, Kyoung-Mee\|Park, Cheolkeun\|Lim, Ho Yeong
PMID:	28382134

95.
Journal:	Med Oncol. 2017 Jun;34(6):101.
Title:	The identification of key genes and pathways in hepatocellular carcinoma by bioinformatics analysis of high-throughput data.
Author:	Zhang, Chaoyang\|Peng, Li\|Zhang, Yaqin\|Liu, Zhaoyang\|Li, Wenling\|Chen, Shilian\|Li, Guancheng
PMID:	28432618

96.
Journal:	Cell Mol Gastroenterol Hepatol. 2017 Jan 17;3(3):484-499.
Title:	Serotonin Activated Hepatic Stellate Cells Contribute to Sex Disparity in Hepatocellular Carcinoma.
Author:	Yang, Qiqi\|Yan, Chuan\|Yin, Chunyue\|Gong, Zhiyuan
PMID:	28462385

97.
Journal:	Am J Transplant. 2017 Oct;17(10):2720-2727.
Title:	Modeling the Iatrogenic Pancreatic Cancer Risk After Islet Autotransplantation in Mouse.
Author:	Dugnani, E\|Pasquale, V\|Liberati, D\|Citro, A\|Cantarelli, E\|Pellegrini, S\|Marra, P\|Canu, T\|Balzano, G\|Scavini, M\|Esposito, A\|Doglioni, C\|Piemonti, L
PMID:	28510280

98.
Journal:	Sci Rep. 2017 Sep 4;7(1):10315.
Title:	Activation of liver stromal cells is associated with male-biased liver tumor initiation in xmrk and Myc transgenic zebrafish.
Author:	Yang, Qiqi\|Yan, Chuan\|Gong, Zhiyuan
PMID:	28871112

99.
Journal:	Front Oncol. 2017 Aug 23;7:190.
Title:	The Oncopig Cancer Model: An Innovative Large Animal Translational Oncology Platform.
Author:	Schachtschneider, Kyle M\|Schwind, Regina M\|Newson, Jordan\|Kinachtchouk, Nickolas\|Rizko, Mark\|Mendoza-Elias, Nasya\|Grippo, Paul\|Principe, Daniel R\|Park, Alex\|Overgaard, Nana H\|Jungersen, Gregers\|Garcia, Kelly D\|Maker, Ajay V\|Rund, Laurie A\|Ozer, Howard\|Gab
PMID:	28879168

100.
Journal:	Clin Cancer Res. 2017 Dec 1;23(23):7209-7216.
Title:	Tumor Heterogeneity Predicts Metastatic Potential in Colorectal Cancer.
Author:	Joung, Je-Gun\|Oh, Bo Young\|Hong, Hye Kyung\|Al-Khalidi, Hisham\|Al-Alem, Faisal\|Lee, Hae-Ock\|Bae, Joon Seol\|Kim, Jinho\|Cha, Hong-Ui\|Alotaibi, Maram\|Cho, Yong Beom\|Hassanain, Mazen\|Park, Woong-Yang\|Lee, Woo Yong
PMID:	28939741

101.
Journal:	Oncotarget. 2017 Jun 29;8(38):63620-63634.
Title:	A validated, transitional and translational porcine model of hepatocellular carcinoma.
Author:	Schachtschneider, Kyle M\|Schwind, Regina M\|Darfour-Oduro, Kwame A\|De, Arun K\|Rund, Lauretta A\|Singh, Kuldeep\|Principe, Daniel R\|Guzman, Grace\|Ray, Charles E Jr\|Ozer, Howard\|Gaba, Ron C\|Schook, Lawrence B
PMID:	28969016

102.
Journal:	Front Med (Lausanne). 2017 Sep 28;4:164.
Title:	Hepatoid Adenocarcinoma of the Stomach: A Challenging Diagnostic and Therapeutic Disease through a Case Report and Review of the Literature.
Author:	Fakhruddin, Najla\|Bahmad, Hisham F\|Aridi, Tarek\|Yammine, Yara\|Mahfouz, Rami\|Boulos, Fouad\|Awada, Ahmad\|Farhat, Fadi
PMID:	29034239

103.
Journal:	Ann Surg Treat Res. 2017 Oct;93(4):173-180.
Title:	Establishing a colorectal cancer liver metastasis patient-derived tumor xenograft model for the evaluation of personalized chemotherapy.
Author:	Jung, Joohee\|Kim, Jisup\|Lim, Hyun Kyung\|Kim, Kyoung Mee\|Lee, Yun Sun\|Park, Joon Seong\|Yoon, Dong Sup
PMID:	29094026

104.
Journal:	Anticancer Res. 2017 Dec;37(12):7063-7068.
Title:	Mucinous Cystic Neoplasms Lined by Abundant Mucinous Epithelium Frequently Involve KRAS Mutations and Malignant Progression.
Author:	Shibata, Hideki\|Ohike, Nobuyuki\|Norose, Tomoko\|Isobe, Tomohide\|Suzuki, Reika\|Imai, Hideyuki\|Shiokawa, Akira\|Aoki, Takeshi\|Murakami, Masahiko\|Mizukami, Hiroki\|Tanaka, Jun-Ichi\|Takimoto, Masafumi
PMID:	29187496

105.
Journal:	J Cancer. 2018 Jan 1;9(1):1-12.
Title:	Aminoacylase 3 Is a New Potential Marker and Therapeutic Target in Hepatocellular Carcinoma.
Author:	Tsirulnikov, Kirill\|Duarte, Sergio\|Ray, Anamika\|Datta, Nakul\|Zarrinpar, Ali\|Hwang, Lin\|Faull, Kym\|Pushkin, Alexander\|Kurtz, Ira
PMID:	29290764

106.
Journal:	Gut. 2018 Jul;67(7):1206-1207.
Title:	Loss of KRAS control as consequence of downregulated microRNA-622 in hepatocellular carcinoma and its potential therapeutic implication.
Author:	Bantel, Heike\|Canbay, Ali
PMID:	29353250

107.
Journal:	Cancer Control. 2018 Jan-Mar;25(1):1073274817744658.
Title:	Primary Liver Cancers, Part 2: Progression Pathways and Carcinogenesis.
Author:	Jiang, Kun\|Centeno, Barbara A
PMID:	29353494

108.
Journal:	Cancer Lett. 2018 May 1;421:161-169.
Title:	Combination of Kras activation and PTEN deletion contributes to murine hepatopancreatic ductal malignancy.
Author:	Lin, Yun-Kai\|Fang, Zheng\|Jiang, Tian-Yi\|Wan, Zheng-Hua\|Pan, Yu-Fei\|Ma, Yun-Han\|Shi, Yuan-Yuan\|Tan, Ye-Xiong\|Dong, Li-Wei\|Zhang, Yong-Jie\|Wang, Hong-Yang
PMID:	29452147

109.
Journal:	Oncogene. 2018 Jun;37(25):3440-3455.
Title:	Mutant KRAS promotes liver metastasis of colorectal cancer, in part, by upregulating the MEK-Sp1-DNMT1-miR-137-YB-1-IGF-IR signaling pathway.
Author:	Chu, Po-Chen\|Lin, Peng-Chan\|Wu, Hsing-Yu\|Lin, Kuen-Tyng\|Wu, Christina\|Bekaii-Saab, Tanios\|Lin, Yih-Jyh\|Lee, Chung-Ta\|Lee, Jeng-Chang\|Chen, Ching-Shih
PMID:	29559746

110.
Journal:	Cancer Sci. 2018 May;109(5):1282-1291.
Title:	Molecular genomic landscapes of hepatobiliary cancer.
Author:	Shibata, Tatsuhiro\|Arai, Yasuhito\|Totoki, Yasushi
PMID:	29573058

111.
Journal:	Dis Model Mech. 2018 May 3;11(8). pii: dmm.032383.
Title:	A novel zebrafish intestinal tumor model reveals a role for cyp7a1-dependent tumor-liver crosstalk in causing adverse effects on the host.
Author:	Enya, Sora\|Kawakami, Koichi\|Suzuki, Yutaka\|Kawaoka, Shinpei
PMID:	29592890

112.
Journal:	Neoplasia. 2018 May;20(5):533-542.
Title:	Activation of Hepatic Stellate Cells During Liver Carcinogenesis Requires Fibrinogen/Integrin alphavbeta5 in Zebrafish.
Author:	Yan, Chuan\|Yang, Qiqi\|Gong, Zhiyuan
PMID:	29649779

113.
Journal:	Oncogene. 2018 Jul;37(28):3894-3908.
Title:	An EGFR ligand promotes EGFR-mutant but not KRAS-mutant lung cancer in vivo.
Author:	Tomoshige, Koichi\|Guo, Minzhe\|Tsuchiya, Tomoshi\|Fukazawa, Takuya\|Fink-Baldauf, Iris M\|Stuart, William D\|Naomoto, Yoshio\|Nagayasu, Takeshi\|Maeda, Yutaka
PMID:	29662194

114.
Journal:	J Med Virol. 2018 Sep;90(9):1516-1523.
Title:	Study of promoter hypomethylation profiles of RAS oncogenes in hepatocellular carcinoma derived from hepatitis C virus genotype 3a in Pakistani population.
Author:	Maryam, Maria\|Idrees, Muhammad
PMID:	29742286

115.
Journal:	Sci Rep. 2018 May 31;8(1):8495.
Title:	Interaction of hepatic stellate cells with neutrophils and macrophages in the liver following oncogenic kras activation in transgenic zebrafish.
Author:	Yang, Qiqi\|Yan, Chuan\|Gong, Zhiyuan
PMID:	29855567

116.
Journal:	Cancer Res. 2018 Aug 15;78(16):4445-4451.
Title:	Kras and Tp53 Mutations Cause Cholangiocyte- and Hepatocyte-Derived Cholangiocarcinoma.
Author:	Hill, Margaret A\|Alexander, William B\|Guo, Bing\|Kato, Yasutaka\|Patra, Krushna\|O'Dell, Michael R\|McCall, Matthew N\|Whitney-Miller, Christa L\|Bardeesy, Nabeel\|Hezel, Aram F
PMID:	29871934

117.
Journal:	Cancer Res. 2018 Sep 1;78(17):4902-4914.
Title:	CTGF Mediates Tumor-Stroma Interactions between Hepatoma Cells and Hepatic Stellate Cells to Accelerate HCC Progression.
Author:	Makino, Yuki\|Hikita, Hayato\|Kodama, Takahiro\|Shigekawa, Minoru\|Yamada, Ryoko\|Sakamori, Ryotaro\|Eguchi, Hidetoshi\|Morii, Eiichi\|Yokoi, Hideki\|Mukoyama, Masashi\|Hiroshi, Suemizu\|Tatsumi, Tomohide\|Takehara, Tetsuo
PMID:	29967264

118.
Journal:	J Thorac Oncol. 2018 Aug 24. pii: S1556-0864(18)32988-5.
Title:	Metformin Enhances Cisplatin-Induced Apoptosis and Prevents Resistance to Cisplatin in Co-mutated KRAS/LKB1 NSCLC.
Author:	Moro, Massimo\|Caiola, Elisa\|Ganzinelli, Monica\|Zulato, Elisabetta\|Rulli, Eliana\|Marabese, Mirko\|Centonze, Giovanni\|Busico, Adele\|Pastorino, Ugo\|de Braud, Filippo G\|Vernieri, Claudio\|Simbolo, Michele\|Bria, Emilio\|Scarpa, Aldo\|Indraccolo, Stefano\|Broggini,
PMID:	30149143

119.
Journal:	Front Genet. 2018 Aug 15;9:309.
Title:	Emergence of Intrahepatic Cholangiocarcinoma: How High-Throughput Technologies Expedite the Solutions for a Rare Cancer Type.
Author:	Shiao, Meng-Shin\|Chiablaem, Khajeelak\|Charoensawan, Varodom\|Ngamphaiboon, Nuttapong\|Jinawath, Natini
PMID:	30158952

120.
Journal:	Cancer Chemother Pharmacol. 2018 Oct 10. pii: 10.1007/s00280-018-3699-0.
Title:	Pharmacokinetic evaluation of the PNC disassembler metarrestin in wild-type and Pdx1-Cre;LSL-Kras(G12D/+);Tp53(R172H/+) (KPC) mice, a genetically engineered model of pancreatic cancer.
Author:	Vilimas, Tomas\|Wang, Amy Q\|Patnaik, Samarjit\|Hughes, Emma A\|Singleton, Marc D\|Knotts, Zachary\|Li, Dandan\|Frankowski, Kevin\|Schlomer, Jerome J\|Guerin, Theresa M\|Springer, Stephanie\|Drennan, Catherine\|Dextras, Christopher\|Wang, Chen\|Gilbert, Debra\|Southall,
PMID:	30306263

121.
Journal:	Oncotarget. 2018 Sep 28;9(76):34279-34288.
Title:	Spatio-temporal tumor heterogeneity in metastatic CRC tumors: a mutational-based approach.
Author:	Del Carmen, Sofia\|Sayagues, Jose Maria\|Bengoechea, Oscar\|Anduaga, Maria Fernanda\|Alcazar, Jose Antonio\|Gervas, Ruth\|Garcia, Jacinto\|Orfao, Alberto\|Bellvis, Luis Munoz\|Sarasquete, Maria Eugenia\|Del Mar Abad, Maria
PMID:	30344942