Primary Site >> Esophagus Cancer
Gene >> KRAS
| 1. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 1992 Aug 31;187(1):515-21. | ||||||||||
| Title: | A point mutation of c-Ki-ras gene was found in human esophageal carcinoma cell lines but not in primary esophageal carcinomas. | ||||||||||
| Author: | Shiga, C|Shiga, K|Sasano, H|Mori, S | ||||||||||
| PMID: | 1520342 | ||||||||||
| 2. | |||||||||||
| Journal: | Am J Clin Pathol. 1993 Dec;100(6):686-9. | ||||||||||
| Title: | Mutation analysis of K-ras oncogenes in gastroenterologic cancers by the amplified created restriction sites method. | ||||||||||
| Author: | Lin, S Y|Chen, P H|Wang, C K|Liu, J D|Siauw, C P|Chen, Y J|Yang, M J|Liu, M H|Chen, T C|Chang, J G | ||||||||||
| PMID: | 8249918 | ||||||||||
| 3. | |||||||||||
| Journal: | Int J Cancer. 1993 Jul 30;54(6):978-82. | ||||||||||
| Title: | Possible role of activated ras genes in human esophageal carcinogenesis. | ||||||||||
| Author: | Galiana, C|Fusco, A|Martel, N|Nishihira, T|Hirohashi, S|Yamasaki, H | ||||||||||
| PMID: | 8335405 | ||||||||||
| 4. | |||||||||||
| Journal: | Mol Carcinog. 1995 Dec;14(4):286-93. | ||||||||||
| Title: | High frequency of Ki-ras amplification and p53 gene mutations in adenocarcinomas of the human esophagus. | ||||||||||
| Author: | Galiana, C|Lozano, J C|Bancel, B|Nakazawa, H|Yamasaki, H | ||||||||||
| PMID: | 8519418 | ||||||||||
| 5. | |||||||||||
| Journal: | Gan To Kagaku Ryoho. 1997 Jul;24 Suppl 2:332-6. | ||||||||||
| Title: | [Findings of genetic changes in small intestinal carcinomas]. | ||||||||||
| Author: | Hirai, A|Hibi, K|Nakamura, H|Fujikake, Y|Matsui, T|Kasai, Y|Akiyama, S|Ito, K|Takagi, H | ||||||||||
| PMID: | 9263525 | ||||||||||
| 6. | |||||||||||
| Journal: | Genes Chromosomes Cancer. 1998 Dec;23(4):317-22. | ||||||||||
| Title: | Infrequent frameshift mutations of polynucleotide repeats in multiple primary cancers affecting the esophagus and other organs. | ||||||||||
| Author: | Iwaya, T|Maesawa, C|Nishizuka, S|Suzuki, Y|Sakata, K|Sato, N|Ikeda, K|Koeda, K|Ogasawara, S|Otsuka, K|Kimura, Y|Aoki, K|Ishida, K|Saito, K|Tamura, G | ||||||||||
| PMID: | 9824204 | ||||||||||
| 7. | |||||||||||
| Journal: | Tumour Biol. 2008;29(6):343-50. | ||||||||||
| Title: | Total number of genome alterations in sporadic gastrointestinal cancer inferred from pooled analyses in the literature. | ||||||||||
| Author: | Nishimura, Takafumi | ||||||||||
| PMID: | 19023234 | ||||||||||
| 8. | |||||||||||
| Journal: | J Hematol Oncol. 2009 Feb 23;2:9. | ||||||||||
| Title: | Updates in Gastrointestinal Oncology - insights from the 2008 44th annual meeting of the American Society of Clinical Oncology. | ||||||||||
| Author: | Javle, Milind|Hsueh, Chung-Tsen | ||||||||||
| PMID: | 19236713 | ||||||||||
| 9. | |||||||||||
| Journal: | Dis Esophagus. 2011 Jul;24(5):374-80. | ||||||||||
| Title: | Identification of EGFR and KRAS mutations in Chinese patients with esophageal squamous cell carcinoma. | ||||||||||
| Author: | Liu, Q-W|Fu, J-H|Luo, K-J|Yang, H-X|Wang, J-Y|Hu, Y|Yang, H|Bella, E | ||||||||||
| PMID: | 21615826 | ||||||||||
| 10. | |||||||||||
| Journal: | Pathol Int. 2012 Feb;62(2):137-43. | ||||||||||
| Title: | Clear cell variant of squamous cell carcinoma originating in the esophagus: report of a case with immunohistochemical and oncogenetic analyses. | ||||||||||
| Author: | Imamhasan, Abdukadir|Mitomi, Hiroyuki|Saito, Tsuyoshi|Arakawa, Atsushi|Yao, Takashi | ||||||||||
| PMID: | 22243784 | ||||||||||
| 11. | |||||||||||
| Journal: | Asian Pac J Cancer Prev. 2012;13(12):6517-21. | ||||||||||
| Title: | RNAi-induced K-Ras gene silencing suppresses growth of EC9706 cells and enhances chemotherapy sensitivity of esophageal cancer. | ||||||||||
| Author: | Wang, Xin-Jie|Zheng, Yu-Ling|Fan, Qing-Xia|Zhang, Xu-Dong | ||||||||||
| PMID: | 23464485 | ||||||||||
| 12. | |||||||||||
| Journal: | Pathol Res Pract. 2012 Jul 15;208(7):398-404. | ||||||||||
| Title: | pERK activation in esophageal carcinomas: clinicopathological associations. | ||||||||||
| Author: | Tasioudi, K E|Saetta, A A|Sakellariou, S|Levidou, G|Michalopoulos, N V|Theodorou, D|Patsouris, E|Korkolopoulou, P | ||||||||||
| PMID: | 22658382 | ||||||||||
| 13. | |||||||||||
| Journal: | Cancer Biol Ther. 2012 Jun;13(8):600-5. | ||||||||||
| Title: | Treatment of malignant, non-resectable, epithelial origin esophageal tumours with the humanized anti-epidermal growth factor antibody nimotuzumab combined with radiation therapy and chemotherapy. | ||||||||||
| Author: | Ramos-Suzarte, Mayra|Lorenzo-Luaces, Patricia|Lazo, Nery Gonzalez|Perez, Mayte Lima|Soriano, Jorge Luis|Gonzalez, Carmen Elena Viada|Hernadez, Ivis Mendoza|Albuerne, Yisel Avila|Moreno, Beatriz Paredes|Alvarez, Eduardo Santiesteban|Callejo, Idael Pineda|A | ||||||||||
| PMID: | 22555809 | ||||||||||
| 14. | |||||||||||
| Journal: | Ann Thorac Surg. 2012 Apr;93(4):1101-6. | ||||||||||
| Title: | Comparative genomics of esophageal adenocarcinoma and squamous cell carcinoma. | ||||||||||
| Author: | Bandla, Santhoshi|Pennathur, Arjun|Luketich, James D|Beer, David G|Lin, Lin|Bass, Adam J|Godfrey, Tony E|Litle, Virginia R | ||||||||||
| PMID: | 22450065 | ||||||||||
| 15. | |||||||||||
| Journal: | BMC Cancer. 2012 Mar 26;12:119. | ||||||||||
| Title: | Prognostic significance of anti-p53 and anti-KRas circulating antibodies in esophageal cancer patients treated with chemoradiotherapy. | ||||||||||
| Author: | Blanchard, Pierre|Quero, Laurent|Pacault, Vincent|Schlageter, Marie-Helene|Baruch-Hennequin, Valerie|Hennequin, Christophe | ||||||||||
| PMID: | 22448886 | ||||||||||
| 16. | |||||||||||
| Journal: | J Tradit Chin Med. 2013 Jun;33(3):361-6. | ||||||||||
| Title: | Effect of blocking Ras signaling pathway with K-Ras siRNA on apoptosis in esophageal squamous carcinoma cells. | ||||||||||
| Author: | Wang, Xinjie|Zheng, Yuling|Fan, Qingxia|Zhang, Xudong | ||||||||||
| PMID: | 24024333 | ||||||||||
| 17. | |||||||||||
| Journal: | Oncol Rep. 2014 Jan;31(1):280-6. | ||||||||||
| Title: | microRNA-27a functions as a tumor suppressor in esophageal squamous cell carcinoma by targeting KRAS. | ||||||||||
| Author: | Zhu, Linan|Wang, Zhiju|Fan, Qingxia|Wang, Ruilin|Sun, Yan | ||||||||||
| PMID: | 24154848 | ||||||||||
| 18. | |||||||||||
| Journal: | World J Gastroenterol. 2014 Oct 28;20(40):14904-12. | ||||||||||
| Title: | MicroRNA signatures in chemotherapy resistant esophageal cancer cell lines. | ||||||||||
| Author: | Hummel, Richard|Sie, Corina|Watson, David I|Wang, Tingting|Ansar, Alfiya|Michael, Michael Z|Van der Hoek, Mark|Haier, Joerg|Hussey, Damian J | ||||||||||
| PMID: | 25356050 | ||||||||||
| 19. | |||||||||||
| Journal: | Mutat Res Rev Mutat Res. 2014 Mar 12. pii: S1383-5742(14)00019-2. | ||||||||||
| Title: | Plk1-targeted therapies in TP53- or RAS-mutated cancer. | ||||||||||
| Author: | Yim, Hyungshin|Erikson, Raymond L | ||||||||||
| PMID: | 24630986 | ||||||||||
| 20. | |||||||||||
| Journal: | Oncol Lett. 2015 Jan;9(1):471-477. Epub 2014 Nov 11. | ||||||||||
| Title: | MicroRNA-27a directly targets KRAS to inhibit cell proliferation in esophageal squamous cell carcinoma. | ||||||||||
| Author: | Jiang, Yuzhi|Duan, Yuting|Zhou, Haibin | ||||||||||
| PMID: | 25436011 | ||||||||||
| 21. | |||||||||||
| Journal: | Ann Surg Oncol. 2015 Oct;22(11):3659-65. | ||||||||||
| Title: | Molecular Characteristics of Basaloid Squamous Cell Carcinoma of the Esophagus: Analysis of KRAS, BRAF, and PIK3CA Mutations and LINE-1 Methylation. | ||||||||||
| Author: | Baba, Yoshifumi|Ishimoto, Takatsugu|Harada, Kazuto|Kosumi, Keisuke|Murata, Asuka|Miyake, Keisuke|Hiyoshi, Yukiharu|Kurashige, Junji|Iwatsuki, Masaaki|Iwagami, Shiro|Miyamoto, Yuji|Sakamoto, Yasuo|Yoshida, Naoya|Oki, Eiji|Iyama, Ken-Ichi|Watanabe, Masayuki | ||||||||||
| PMID: | 25691283 | ||||||||||
| 22. | |||||||||||
| Journal: | Cancer Biol Ther. 2015;16(5):764-9. | ||||||||||
| Title: | Tumor profiling of gastric and esophageal carcinoma reveal different treatment options. | ||||||||||
| Author: | Miura, John T|Xiu, Joanne|Thomas, James|George, Ben|Carron, Benjamin R|Tsai, Susan|Johnston, Fabian M|Turaga, Kiran K|Gamblin, T Clark | ||||||||||
| PMID: | 25778705 | ||||||||||
| 23. | |||||||||||
| Journal: | PLoS One. 2015 Mar 31;10(3):e0122375. | ||||||||||
| Title: | MicroRNA signature characterizes primary tumors that metastasize in an esophageal adenocarcinoma rat model. | ||||||||||
| Author: | Zaidi, Ali H|Saldin, Lindsey T|Kelly, Lori A|Bergal, Linda|Londono, Ricardo|Kosovec, Juliann E|Komatsu, Yoshihiro|Kasi, Pashtoon M|Shetty, Amit A|Keane, Timothy J|Thakkar, Shyam J|Huleihel, Luai|Landreneau, Rodney J|Badylak, Stephen F|Jobe, Blair A | ||||||||||
| PMID: | 25826212 | ||||||||||
| 24. | |||||||||||
| Journal: | Oncologist. 2015 Oct;20(10):1132-9. | ||||||||||
| Title: | Comprehensive Genomic Profiling of Advanced Esophageal Squamous Cell Carcinomas and Esophageal Adenocarcinomas Reveals Similarities and Differences. | ||||||||||
| Author: | Wang, Kai|Johnson, Adrienne|Ali, Siraj M|Klempner, Samuel J|Bekaii-Saab, Tanios|Vacirca, Jeffrey L|Khaira, Depinder|Yelensky, Roman|Chmielecki, Juliann|Elvin, Julia A|Lipson, Doron|Miller, Vincent A|Stephens, Philip J|Ross, Jeffrey S | ||||||||||
| PMID: | 26336083 | ||||||||||
| 25. | |||||||||||
| Journal: | Genet Mol Res. 2015 Aug 3;14(3):8810-8. | ||||||||||
| Title: | Characterization and effects of miR-21 expression in esophageal cancer. | ||||||||||
| Author: | Wen, S-W|Zhang, Y-F|Li, Y|Liu, Z-X|Lv, H-L|Li, Z-H|Xu, Y-Z|Zhu, Y-G|Tian, Z-Q | ||||||||||
| PMID: | 26345812 | ||||||||||
| 26. | |||||||||||
| Journal: | Zhonghua Yi Xue Za Zhi. 2015 Dec 15;95(47):3839-42. | ||||||||||
| Title: | [Clinical implications of the concentration and EGFR/KRAS mutations of plasma cell free DNA of patients with lung cancer and esophageal cancer]. | ||||||||||
| Author: | Zhang, Ruixiang|Li, Yin|Chen, Yawei|Liu, Xianben|Wang, Zongfei|Sun, Haibo|Zheng, Yan|Ding, Zhidan|Lan, Ling|Li, Mingzhen|Qin, Jianjun|Chen, Xiankai | ||||||||||
| PMID: | 27337801 | ||||||||||
| 27. | |||||||||||
| Journal: | Pharmacogenomics J. 2016 Jun;16(3):249-65. | ||||||||||
| Title: | Germline and somatic genetic predictors of pathological response in neoadjuvant settings of rectal and esophageal cancers: systematic review and meta-analysis. | ||||||||||
| Author: | Salnikova, L E|Kolobkov, D S | ||||||||||
| PMID: | 26122021 | ||||||||||
| 28. | |||||||||||
| Journal: | Cancer Genomics Proteomics. 2016 May-Jun;13(3):231-8. | ||||||||||
| Title: | TP53, PIK3CA, FBXW7 and KRAS Mutations in Esophageal Cancer Identified by Targeted Sequencing. | ||||||||||
| Author: | Zheng, Huili|Wang, Yan|Tang, Chuanning|Jones, Lindsey|Ye, Hua|Zhang, Guangchun|Cao, Weihai|Li, Jingwen|Liu, Lifeng|Liu, Zhencong|Zhang, Chao|Lou, Feng|Liu, Zhiyuan|Li, Yangyang|Shi, Zhenfen|Zhang, Jingbo|Zhang, Dandan|Sun, Hong|Dong, Haichao|Dong, Zhishou | ||||||||||
| PMID: | 27107065 | ||||||||||
| 29. | |||||||||||
| Journal: | Mol Med Rep. 2016 Jul;14(1):283-8. | ||||||||||
| Title: | Aberrant methylation of microRNA-193b in human Barrett's esophagus and esophageal adenocarcinoma. | ||||||||||
| Author: | Lu, Lin|Liu, Tianyu|Gao, Jian|Zeng, Hanqing|Chen, Jia|Gu, Xiling|Mei, Zhechuan | ||||||||||
| PMID: | 27176876 | ||||||||||
| 30. | |||||||||||
| Journal: | Future Oncol. 2017 Apr;13(10):919-934. | ||||||||||
| Title: | Translating genomic profiling to gastrointestinal cancer treatment. | ||||||||||
| Author: | Harada, Kazuto|Mizrak Kaya, Dilsa|Shimodaira, Yusuke|Song, Shumei|Baba, Hideo|Ajani, Jaffer A | ||||||||||
| PMID: | 28067073 | ||||||||||
| 31. | |||||||||||
| Journal: | J Clin Oncol. 2017 Jul 10;35(20):2279-2287. | ||||||||||
| Title: | Gefitinib and EGFR Gene Copy Number Aberrations in Esophageal Cancer. | ||||||||||
| Author: | Petty, Russell D|Dahle-Smith, Asa|Stevenson, David A J|Osborne, Aileen|Massie, Doreen|Clark, Caroline|Murray, Graeme I|Dutton, Susan J|Roberts, Corran|Chong, Irene Y|Mansoor, Wasat|Thompson, Joyce|Harrison, Mark|Chatterjee, Anirban|Falk, Stephen J|Elyan, | ||||||||||
| PMID: | 28537764 | ||||||||||
| 32. | |||||||||||
| Journal: | Cancer Res. 2017 Sep 29. pii: canres.0938.2017. | ||||||||||
| Title: | Multiregional sequencing reveals genomic alterations and clonal dynamics in primary malignant melanoma of the esophagus. | ||||||||||
| Author: | Li, Jingjing|Yan, Shi|Liu, Zhen|Zhou, Yong|Pan, Yaqi|Yuan, Wenqing|Liu, Mengfei|Tan, Qin|Tian, Geng|Dong, Bin|Cai, Hong|Wu, Nan|Ke, Yang | ||||||||||
| PMID: | 28972077 | ||||||||||
| 33. | |||||||||||
| Journal: | Oncotarget. 2017 Jun 27;8(41):69610-69621. | ||||||||||
| Title: | Mutation landscape and intra-tumor heterogeneity of two MANECs of the esophagus revealed by multi-region sequencing. | ||||||||||
| Author: | Yuan, Wenqing|Liu, Zhen|Lei, Wanjun|Sun, Li|Yang, Haijun|Wang, Yu|Ramdas, Shweta|Dong, Xiao|Xu, Ruiping|Cai, Hong|Li, Jun Z|Ke, Yang | ||||||||||
| PMID: | 29050228 | ||||||||||