Primary Site >> Esophagus Cancer
Gene >> KRAS
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Ref: A point mutation of c-Ki-ras gene was found in human esophageal carcinoma cell lines but not in primary esophageal carcinomas. PMID: 1520342 |
Ref: Mutation analysis of K-ras oncogenes in gastroenterologic cancers by the amplified created restriction sites method. PMID: 8249918 Ref: Possible role of activated ras genes in human esophageal carcinogenesis. PMID: 8335405 |
Ref: High frequency of Ki-ras amplification and p53 gene mutations in adenocarcinomas of the human esophagus. PMID: 8519418 |
Ref: [Findings of genetic changes in small intestinal carcinomas]. PMID: 9263525 |
Ref: Infrequent frameshift mutations of polynucleotide repeats in multiple primary cancers affecting the esophagus and other organs. PMID: 9824204 |
Ref: Total number of genome alterations in sporadic gastrointestinal cancer inferred from pooled analyses in the literature. PMID: 19023234 |
Ref: Updates in Gastrointestinal Oncology - insights from the 2008 44th annual meeting of the American Society of Clinical Oncology. PMID: 19236713 |
Ref: Identification of EGFR and KRAS mutations in Chinese patients with esophageal squamous cell carcinoma. PMID: 21615826 |
Ref: Clear cell variant of squamous cell carcinoma originating in the esophagus: report of a case with immunohistochemical and oncogenetic analyses. PMID: 22243784 Ref: Prognostic significance of anti-p53 and anti-KRas circulating antibodies in esophageal cancer patients treated with chemoradiotherapy. PMID: 22448886 Ref: Comparative genomics of esophageal adenocarcinoma and squamous cell carcinoma. PMID: 22450065 Ref: Treatment of malignant, non-resectable, epithelial origin esophageal tumours with the humanized anti-epidermal growth factor antibody nimotuzumab combined with radiation therapy and chemotherapy. PMID: 22555809 Ref: pERK activation in esophageal carcinomas: clinicopathological associations. PMID: 22658382 Ref: RNAi-induced K-Ras gene silencing suppresses growth of EC9706 cells and enhances chemotherapy sensitivity of esophageal cancer. PMID: 23464485 |
Ref: Effect of blocking Ras signaling pathway with K-Ras siRNA on apoptosis in esophageal squamous carcinoma cells. PMID: 24024333 |
Ref: microRNA-27a functions as a tumor suppressor in esophageal squamous cell carcinoma by targeting KRAS. PMID: 24154848 Ref: Plk1-targeted therapies in TP53- or RAS-mutated cancer. PMID: 24630986 Ref: MicroRNA signatures in chemotherapy resistant esophageal cancer cell lines. PMID: 25356050 |
Ref: MicroRNA-27a directly targets KRAS to inhibit cell proliferation in esophageal squamous cell carcinoma. PMID: 25436011 Ref: Molecular Characteristics of Basaloid Squamous Cell Carcinoma of the Esophagus: Analysis of KRAS, BRAF, and PIK3CA Mutations and LINE-1 Methylation. PMID: 25691283 Ref: Tumor profiling of gastric and esophageal carcinoma reveal different treatment options. PMID: 25778705 Ref: MicroRNA signature characterizes primary tumors that metastasize in an esophageal adenocarcinoma rat model. PMID: 25826212 Ref: Comprehensive Genomic Profiling of Advanced Esophageal Squamous Cell Carcinomas and Esophageal Adenocarcinomas Reveals Similarities and Differences. PMID: 26336083 Ref: Characterization and effects of miR-21 expression in esophageal cancer. PMID: 26345812 Ref: [Clinical implications of the concentration and EGFR/KRAS mutations of plasma cell free DNA of patients with lung cancer and esophageal cancer]. PMID: 27337801 |
Ref: Germline and somatic genetic predictors of pathological response in neoadjuvant settings of rectal and esophageal cancers: systematic review and meta-analysis. PMID: 26122021 Ref: TP53, PIK3CA, FBXW7 and KRAS Mutations in Esophageal Cancer Identified by Targeted Sequencing. PMID: 27107065 Ref: Aberrant methylation of microRNA-193b in human Barrett's esophagus and esophageal adenocarcinoma. PMID: 27176876 |
Ref: Translating genomic profiling to gastrointestinal cancer treatment. PMID: 28067073 Ref: Gefitinib and EGFR Gene Copy Number Aberrations in Esophageal Cancer. PMID: 28537764 Ref: Multiregional sequencing reveals genomic alterations and clonal dynamics in primary malignant melanoma of the esophagus. PMID: 28972077 Ref: Mutation landscape and intra-tumor heterogeneity of two MANECs of the esophagus revealed by multi-region sequencing. PMID: 29050228 |