Primary Site >> Colorectal Cancer

Gene >> KMT2A

Journal: Nat Genet. 2000 Mar;24(3):300-3.
Title: Mutations truncating the EP300 acetylase in human cancers.
Author: Gayther, S A|Batley, S J|Linger, L|Bannister, A|Thorpe, K|Chin, S F|Daigo, Y|Russell, P|Wilson, A|Sowter, H M|Delhanty, J D|Ponder, B A|Kouzarides, T|Caldas, C
PMID: 10700188
Journal: Cancer Res. 2001 Sep 1;61(17):6345-9.
Title: Identification of AF17 as a downstream gene of the beta-catenin/T-cell factor pathway and its involvement in colorectal carcinogenesis.
Author: Lin, Y M|Ono, K|Satoh, S|Ishiguro, H|Fujita, M|Miwa, N|Tanaka, T|Tsunoda, T|Yang, K C|Nakamura, Y|Furukawa, Y
PMID: 11522623
Journal: Genes Dev. 2006 Mar 1;20(5):586-600.
Title: The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes.
Author: Sierra, Jose|Yoshida, Tomonori|Joazeiro, Claudio A|Jones, Katherine A
PMID: 16510874
Journal: Eur J Haematol. 2007 Jun;78(6):543-4.
Title: Acute myeloid leukaemia secondary to treatment with capecitabine for metastatic colorectal cancer.
Author: Shapiro, Susan|Hughes, George|Al-Obaidi, Magda Jabbar|O'Reilly, Eamon|Ramesh, Subramanian|Smith, Jason|Ahmad, Riz|Dawson, Charlotte|Riddle, Pippa|Sekhar, Mallika
PMID: 17509107
Journal: Cancer Cell Int. 2010 Apr 30;10:13.
Title: Epigenetic regulator MLL2 shows altered expression in cancer cell lines and tumors from human breast and colon.
Author: Natarajan, Thanemozhi G|Kallakury, Bhaskar V|Sheehan, Christine E|Bartlett, Margaret B|Ganesan, Natarajan|Preet, Anju|Ross, Jeffrey S|FitzGerald, Kevin T
PMID: 20433758
Journal: ACS Chem Biol. 2015 Jan 16;10(1):109-14.
Title: Regulation of Wnt signaling target gene expression by the histone methyltransferase DOT1L.
Author: Gibbons, Garrett S|Owens, Scott R|Fearon, Eric R|Nikolovska-Coleska, Zaneta
PMID: 25361163
Journal: Oncotarget. 2016 Jun 28;7(26):40594-40620.
Title: Interaction of DNA demethylase and histone methyltransferase upregulates Nrf2 in 5-fluorouracil-resistant colon cancer cells.
Author: Kang, Kyoung Ah|Piao, Mei Jing|Ryu, Yea Seong|Kang, Hee Kyoung|Chang, Weon Young|Keum, Young Sam|Hyun, Jin Won
PMID: 27259240
Journal: Nat Commun. 2017 Apr 25;8:15146.
Title: KDM3 epigenetically controls tumorigenic potentials of human colorectal cancer stem cells through Wnt/beta-catenin signalling.
Author: Li, Jiong|Yu, Bo|Deng, Peng|Cheng, Yingduan|Yu, Yongxin|Kevork, Kareena|Ramadoss, Sivakumar|Ding, Xiangming|Li, Xinmin|Wang, Cun-Yu
PMID: 28440295
Journal: Gene. 2017 Sep 20;629:16-28.
Title: Histone methylase MLL1 coordinates with HIF and regulate lncRNA HOTAIR expression under hypoxia.
Author: Bhan, Arunoday|Deb, Paromita|Shihabeddin, Nadine|Ansari, Khairul I|Brotto, Marco|Mandal, Subhrangsu S
PMID: 28756022
Journal: BMC Cancer. 2018 Jun 20;18(1):673.
Title: WDR5 supports colon cancer cells by promoting methylation of H3K4 and suppressing DNA damage.
Author: Neilsen, Beth K|Chakraborty, Binita|McCall, Jamie L|Frodyma, Danielle E|Sleightholm, Richard L|Fisher, Kurt W|Lewis, Robert E
PMID: 29925347
Journal: Oncologist. 2018 Jul 17. pii: theoncologist.2018-0117.
Title: Impact of Patient Age on Molecular Alterations of Left-Sided Colorectal Tumors.
Author: Puccini, Alberto|Lenz, Heinz-Josef|Marshall, John L|Arguello, David|Raghavan, Derek|Korn, W Michael|Weinberg, Benjamin A|Poorman, Kelsey|Heeke, Arielle L|Philip, Philip A|Shields, Anthony F|Goldberg, Richard M|Salem, Mohamed E
PMID: 30018131
Journal: Scand J Gastroenterol. 2018 Aug;53(8):964-971.
Title: MLLT10 promotes tumor migration, invasion, and metastasis in human colorectal cancer.
Author: Jing, Xiaoqian|Wu, Haoxuan|Cheng, Xi|Chen, Xianze|Zhang, Yaqi|Shi, Minmin|Zhang, Tao|Wang, Xiongjun|Zhao, Ren
PMID: 30102091