Primary Site >> Colorectal Cancer
Gene >> KMT2A
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Ref: Mutations truncating the EP300 acetylase in human cancers. PMID: 10700188 |
Ref: Identification of AF17 as a downstream gene of the beta-catenin/T-cell factor pathway and its involvement in colorectal carcinogenesis. PMID: 11522623 |
Ref: The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes. PMID: 16510874 |
Ref: Acute myeloid leukaemia secondary to treatment with capecitabine for metastatic colorectal cancer. PMID: 17509107 |
Ref: Epigenetic regulator MLL2 shows altered expression in cancer cell lines and tumors from human breast and colon. PMID: 20433758 |
Ref: Regulation of Wnt signaling target gene expression by the histone methyltransferase DOT1L. PMID: 25361163 |
Ref: Interaction of DNA demethylase and histone methyltransferase upregulates Nrf2 in 5-fluorouracil-resistant colon cancer cells. PMID: 27259240 |
Ref: KDM3 epigenetically controls tumorigenic potentials of human colorectal cancer stem cells through Wnt/beta-catenin signalling. PMID: 28440295 Ref: Histone methylase MLL1 coordinates with HIF and regulate lncRNA HOTAIR expression under hypoxia. PMID: 28756022 |
Ref: WDR5 supports colon cancer cells by promoting methylation of H3K4 and suppressing DNA damage. PMID: 29925347 Ref: Impact of Patient Age on Molecular Alterations of Left-Sided Colorectal Tumors. PMID: 30018131 Ref: MLLT10 promotes tumor migration, invasion, and metastasis in human colorectal cancer. PMID: 30102091 |