Primary Site >> Liver Cancer
Gene >> KLF6
| 1. | |||||||||||
| Journal: | Zhonghua Wai Ke Za Zhi. 2004 Oct 22;42(20):1258-61. | ||||||||||
| Title: | [A candidate tumor suppressor gene mutated in primary hepatocellular carcinoma: kruppel-like factor 6]. | ||||||||||
| Author: | Wang, Shao-ping|Chen, Xiao-ping|Qiu, Fa-zu | ||||||||||
| PMID: | 15598377 | ||||||||||
| 2. | |||||||||||
| Journal: | Hepatology. 2004 Nov;40(5):1047-52. | ||||||||||
| Title: | Frequent inactivation of the tumor suppressor Kruppel-like factor 6 (KLF6) in hepatocellular carcinoma. | ||||||||||
| Author: | Kremer-Tal, Sigal|Reeves, Helen L|Narla, Goutham|Thung, Swan N|Schwartz, Myron|Difeo, Analisa|Katz, Amanda|Bruix, Jordi|Bioulac-Sage, Paulette|Martignetti, John A|Friedman, Scott L | ||||||||||
| PMID: | 15486921 | ||||||||||
| 3. | |||||||||||
| Journal: | J Huazhong Univ Sci Technolog Med Sci. 2004;24(6):585-7. | ||||||||||
| Title: | KLF6mRNA expression in primary hepatocellular carcinoma. | ||||||||||
| Author: | Wang, Shaoping|Chen, Xiaoping|Zhang, Wanguang|Qiu, Fazu | ||||||||||
| PMID: | 15791848 | ||||||||||
| 4. | |||||||||||
| Journal: | Oncogene. 2005 Nov 3;24(48):7253-6. | ||||||||||
| Title: | Absence of mutation in the putative tumor-suppressor gene KLF6 in colorectal cancers. | ||||||||||
| Author: | Lievre, Astrid|Landi, Bruno|Cote, Jean-Francois|Veyrie, Nicolas|Zucman-Rossi, Jessica|Berger, Anne|Laurent-Puig, Pierre | ||||||||||
| PMID: | 16044160 | ||||||||||
| 5. | |||||||||||
| Journal: | Zhonghua Gan Zang Bing Za Zhi. 2006 Feb;14(2):109-13. | ||||||||||
| Title: | [Mutations of the tumor suppressor Kruppel-like factor 6 (KLF6) gene in hepatocellular carcinoma and its effect of growth suppression on human hepatocellular carcinoma cell line HepG2]. | ||||||||||
| Author: | Pan, Xiu-cheng|Chen, Zhi|Chen, Feng|Chen, Xiao-hong|Zhou, Cheng|Yang, Zheng-gang | ||||||||||
| PMID: | 16494780 | ||||||||||
| 6. | |||||||||||
| Journal: | J Gastroenterol Hepatol. 2006 Aug;21(8):1286-9. | ||||||||||
| Title: | Genetic and epigenetic alterations of the KLF6 gene in hepatocellular carcinoma. | ||||||||||
| Author: | Song, Jaehwi|Kim, Chang Jae|Cho, Yong Gu|Kim, Su Young|Nam, Suk Woo|Lee, Sug Hyung|Yoo, Nam Jin|Lee, Jung Young|Park, Won Sang | ||||||||||
| PMID: | 16872311 | ||||||||||
| 7. | |||||||||||
| Journal: | J Zhejiang Univ Sci B. 2006 Oct;7(10):830-6. | ||||||||||
| Title: | Inactivation of the tumor suppressor Kruppel-like factor 6 (KLF6) by mutation or decreased expression in hepatocellular carcinomas. | ||||||||||
| Author: | Pan, Xiu-cheng|Chen, Zhi|Chen, Feng|Chen, Xiao-hong|Jin, Han-yin|Xu, Xiao-yan | ||||||||||
| PMID: | 16972326 | ||||||||||
| 8. | |||||||||||
| Journal: | Oncology. 2006;71(1-2):77-85. | ||||||||||
| Title: | Methylation status of genes upregulated by demethylating agent 5-aza-2'-deoxycytidine in hepatocellular carcinoma. | ||||||||||
| Author: | Hirasawa, Yuichi|Arai, Makoto|Imazeki, Fumio|Tada, Motohisa|Mikata, Rintaro|Fukai, Kenichi|Miyazaki, Masaru|Ochiai, Takenori|Saisho, Hiromitsu|Yokosuka, Osamu | ||||||||||
| PMID: | 17341888 | ||||||||||
| 9. | |||||||||||
| Journal: | J Hepatol. 2007 Apr;46(4):645-54. | ||||||||||
| Title: | Downregulation of KLF6 is an early event in hepatocarcinogenesis, and stimulates proliferation while reducing differentiation. | ||||||||||
| Author: | Kremer-Tal, Sigal|Narla, Goutham|Chen, Yingbei|Hod, Eldad|DiFeo, Analisa|Yea, Steven|Lee, Ju-Seog|Schwartz, Myron|Thung, Swan N|Fiel, Isabel M|Banck, Michaela|Zimran, Eran|Thorgeirsson, Snorri S|Mazzaferro, Vincenzo|Bruix, Jordi|Martignetti, John A|Llovet | ||||||||||
| PMID: | 17196295 | ||||||||||
| 10. | |||||||||||
| Journal: | Oncogene. 2007 Jun 28;26(30):4428-34. | ||||||||||
| Title: | In vivo regulation of p21 by the Kruppel-like factor 6 tumor-suppressor gene in mouse liver and human hepatocellular carcinoma. | ||||||||||
| Author: | Narla, G|Kremer-Tal, S|Matsumoto, N|Zhao, X|Yao, S|Kelley, K|Tarocchi, M|Friedman, S L | ||||||||||
| PMID: | 17297474 | ||||||||||
| 11. | |||||||||||
| Journal: | Cell Death Differ. 2007 Jun;14(6):1202-10. | ||||||||||
| Title: | KLF6 transcription factor protects hepatocellular carcinoma-derived cells from apoptosis. | ||||||||||
| Author: | Sirach, E|Bureau, C|Peron, J M|Pradayrol, L|Vinel, J P|Buscail, L|Cordelier, P | ||||||||||
| PMID: | 17347668 | ||||||||||
| 12. | |||||||||||
| Journal: | J Exp Clin Cancer Res. 2007 Mar;26(1):117-24. | ||||||||||
| Title: | Loss of expression of Kruppel-like factor 6 in primary hepatocellular carcinoma and hepatoma cell lines. | ||||||||||
| Author: | Wang, S P|Zhou, H J|Chen, X P|Ren, G Y|Ruan, X X|Zhang, Y|Zhang, R L|Chen, J | ||||||||||
| PMID: | 17550140 | ||||||||||
| 13. | |||||||||||
| Journal: | J Gastroenterol Hepatol. 2008 Jan;23(1):78-86. | ||||||||||
| Title: | Expression of the transcription factor Klf6 in cirrhosis, macronodules, and hepatocellular carcinoma. | ||||||||||
| Author: | Bureau, Christophe|Peron, J M|Bouisson, Michele|Danjoux, Marie|Selves, Janick|Bioulac-Sage, Paulette|Balabaud, Charles|Torrisani, Jerome|Cordelier, Pierre|Buscail, Louis|Vinel, Jean Pierre | ||||||||||
| PMID: | 18171345 | ||||||||||
| 14. | |||||||||||
| Journal: | Exp Mol Pathol. 2008 Apr;84(2):102-12. | ||||||||||
| Title: | Fat10 is an epigenetic marker for liver preneoplasia in a drug-primed mouse model of tumorigenesis. | ||||||||||
| Author: | Oliva, Joan|Bardag-Gorce, Fawzia|French, Barbara A|Li, Jun|McPhaul, Laron|Amidi, Fataneh|Dedes, Jeniffer|Habibi, Amir|Nguyen, Sheila|French, Samuel W | ||||||||||
| PMID: | 18280469 | ||||||||||
| 15. | |||||||||||
| Journal: | Gastroenterology. 2008 May;134(5):1521-31. | ||||||||||
| Title: | Ras promotes growth by alternative splicing-mediated inactivation of the KLF6 tumor suppressor in hepatocellular carcinoma. | ||||||||||
| Author: | Yea, Steven|Narla, Goutham|Zhao, Xiao|Garg, Rakhi|Tal-Kremer, Sigal|Hod, Eldad|Villanueva, Augusto|Loke, Johnny|Tarocchi, Mirko|Akita, Kunihara|Shirasawa, Senji|Sasazuki, Takehiko|Martignetti, John A|Llovet, Josep M|Friedman, Scott L | ||||||||||
| PMID: | 18471523 | ||||||||||
| 16. | |||||||||||
| Journal: | Zhonghua Gan Zang Bing Za Zhi. 2008 Sep;16(9):683-7. | ||||||||||
| Title: | [Effect of KLF6 and its splice variant KLF6V on proliferation and differentiation of human hepatocellular carcinoma HepG2 cells]. | ||||||||||
| Author: | Pan, Xiu-cheng|Chen, Zhi|Ji, Fang|Guo, Zhong-sheng|Chen, Min|Fu, Juan-juan | ||||||||||
| PMID: | 18822210 | ||||||||||
| 17. | |||||||||||
| Journal: | J Cell Biochem. 2010 Dec 1;111(5):1244-51. | ||||||||||
| Title: | Characterization of E2F3a function in HepG2 liver cancer cells. | ||||||||||
| Author: | Li, Wei|Ni, Guo-Xin|Zhang, Ping|Zhang, Zheng-Xi|Li, Wei|Wu, Qiang | ||||||||||
| PMID: | 20803551 | ||||||||||
| 18. | |||||||||||
| Journal: | J Huazhong Univ Sci Technolog Med Sci. 2010 Aug;30(4):470-6. | ||||||||||
| Title: | Frequent down-regulation and deletion of KLF6 in primary hepatocellular carcinoma. | ||||||||||
| Author: | Wang, Shaoping|Kang, Lili|Chen, Xiaoping|Zhou, Hejun | ||||||||||
| PMID: | 20714872 | ||||||||||
| 19. | |||||||||||
| Journal: | FEBS Lett. 2010 Mar 5;584(5):1006-10. | ||||||||||
| Title: | Tumor suppressor activity of KLF6 mediated by downregulation of the PTTG1 oncogene. | ||||||||||
| Author: | Lee, Ursula E|Ghiassi-Nejad, Zahra|Paris, Andrew J|Yea, Steven|Narla, Goutham|Walsh, Martin|Friedman, Scott L | ||||||||||
| PMID: | 20116377 | ||||||||||
| 20. | |||||||||||
| Journal: | J Hepatol. 2010 Nov;53(5):880-8. | ||||||||||
| Title: | The SV2 variant of KLF6 is down-regulated in hepatocellular carcinoma and displays anti-proliferative and pro-apoptotic functions. | ||||||||||
| Author: | Hanoun, Naima|Bureau, Christophe|Diab, Thoria|Gayet, Odile|Dusetti, Nelson|Selves, Janick|Vinel, Jean-Pierre|Buscail, Louis|Cordelier, Pierre|Torrisani, Jerome | ||||||||||
| PMID: | 20801538 | ||||||||||
| 21. | |||||||||||
| Journal: | Hepatology. 2011 Aug;54(2):522-31. | ||||||||||
| Title: | Carcinogen-induced hepatic tumors in KLF6+/- mice recapitulate aggressive human hepatocellular carcinoma associated with p53 pathway deregulation. | ||||||||||
| Author: | Tarocchi, Mirko|Hannivoort, Rebekka|Hoshida, Yujin|Lee, Ursula E|Vetter, Diana|Narla, Goutham|Villanueva, Augusto|Oren, Moshe|Llovet, Josep M|Friedman, Scott L | ||||||||||
| PMID: | 21563203 | ||||||||||
| 22. | |||||||||||
| Journal: | Hepatogastroenterology. 2012 Mar-Apr;59(114):473-6. | ||||||||||
| Title: | New candidate tumor-suppressor gene KLF6 and its splice variant KLF6 SV2 counterbalancing expression in primary hepatocarcinoma. | ||||||||||
| Author: | Zhenzhen, Zhou|De'an, Tian|Limin, Xia|Wei, Yan|Min, Luo | ||||||||||
| PMID: | 21940380 | ||||||||||
| 23. | |||||||||||
| Journal: | Hepatology. 2012 Oct;56(4):1361-70. | ||||||||||
| Title: | Enhanced hepatocarcinogenesis in mouse models and human hepatocellular carcinoma by coordinate KLF6 depletion and increased messenger RNA splicing. | ||||||||||
| Author: | Vetter, Diana|Cohen-Naftaly, Michal|Villanueva, Augusto|Lee, Youngmin A|Kocabayoglu, Peri|Hannivoort, Rebekka|Narla, Goutham|M Llovet, Josep|Thung, Swan N|Friedman, Scott L | ||||||||||
| PMID: | 22535637 | ||||||||||
| 24. | |||||||||||
| Journal: | J Clin Invest. 2012 Aug;122(8):2884-97. | ||||||||||
| Title: | MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis. | ||||||||||
| Author: | Tsai, Wei-Chih|Hsu, Sheng-Da|Hsu, Chu-Sui|Lai, Tsung-Ching|Chen, Shu-Jen|Shen, Roger|Huang, Yi|Chen, Hua-Chien|Lee, Chien-Hsin|Tsai, Ting-Fen|Hsu, Ming-Ta|Wu, Jaw-Ching|Huang, Hsien-Da|Shiao, Ming-Shi|Hsiao, Michael|Tsou, Ann-Ping | ||||||||||
| PMID: | 22820290 | ||||||||||
| 25. | |||||||||||
| Journal: | Mol Cancer Res. 2012 Sep;10(9):1216-27. | ||||||||||
| Title: | Hepatocyte growth factor enhances alternative splicing of the Kruppel-like factor 6 (KLF6) tumor suppressor to promote growth through SRSF1. | ||||||||||
| Author: | Munoz, Ursula|Puche, Juan E|Hannivoort, Rebekka|Lang, Ursula E|Cohen-Naftaly, Michal|Friedman, Scott L | ||||||||||
| PMID: | 22859706 | ||||||||||
| 26. | |||||||||||
| Journal: | Cancers (Basel). 2013 Dec 19;6(1):28-41. | ||||||||||
| Title: | The Role of the 3' Untranslated Region in the Post-Transcriptional Regulation of KLF6 Gene Expression in Hepatocellular Carcinoma. | ||||||||||
| Author: | Diab, Thoria|Hanoun, Naima|Bureau, Christophe|Christol, Camille|Buscail, Louis|Cordelier, Pierre|Torrisani, Jerome | ||||||||||
| PMID: | 24378751 | ||||||||||
| 27. | |||||||||||
| Journal: | Oncogene. 2013 Sep 19;32(38):4557-64. | ||||||||||
| Title: | GSK3beta phosphorylation of the KLF6 tumor suppressor promotes its transactivation of p21. | ||||||||||
| Author: | Lang, U E|Kocabayoglu, P|Cheng, G Z|Ghiassi-Nejad, Z|Munoz, U|Vetter, D|Eckstein, D A|Hannivoort, R A|Walsh, M J|Friedman, S L | ||||||||||
| PMID: | 23085750 | ||||||||||
| 28. | |||||||||||
| Journal: | RNA Biol. 2014;11(7):845-54. | ||||||||||
| Title: | Identification of miRNAs that specifically target tumor suppressive KLF6-FL rather than oncogenic KLF6-SV1 isoform. | ||||||||||
| Author: | Liang, Wei-Cheng|Wang, Yan|Xiao, Li-Jia|Wang, Yu-Bing|Fu, Wei-Ming|Wang, Wei-Mao|Jiang, Hui-Qing|Qi, Wei|Wan, David Chi-Cheong|Zhang, Jin-Fang|Waye, Mary Miu-Yee | ||||||||||
| PMID: | 24921656 | ||||||||||
| 29. | |||||||||||
| Journal: | Tumour Biol. 2015 Feb;36(2):533-41. | ||||||||||
| Title: | Kruppel-like factors in hepatocellular carcinoma. | ||||||||||
| Author: | Lu, Xiao-Jie|Shi, Yan|Chen, Jin-Lian|Ma, Shijie | ||||||||||
| PMID: | 25652467 | ||||||||||
| 30. | |||||||||||
| Journal: | Oncogene. 2016 Sep 1;35(35):4653-62. | ||||||||||
| Title: | A novel KLF6-Rho GTPase axis regulates hepatocellular carcinoma cell migration and dissemination. | ||||||||||
| Author: | Ahronian, L G|Zhu, L J|Chen, Y-W|Chu, H-C|Klimstra, D S|Lewis, B C | ||||||||||
| PMID: | 26876204 | ||||||||||
| 31. | |||||||||||
| Journal: | Oncotarget. 2016 May 10;7(19):27975-87. | ||||||||||
| Title: | Interaction of KLF6 and Sp1 regulates basigin-2 expression mediated proliferation, invasion and metastasis in hepatocellular carcinoma. | ||||||||||
| Author: | Kong, Ling-Min|Yao, Li|Lu, Ning|Dong, Ya-Lu|Zhang, Jing|Wang, Yong-Qiang|Liu, Lili|Zhang, He-Long|Huang, Jian-Guo|Liao, Cheng-Gong | ||||||||||
| PMID: | 27057625 | ||||||||||
| 32. | |||||||||||
| Journal: | Int J Immunopathol Pharmacol. 2016 Dec;29(4):666-675. | ||||||||||
| Title: | Kruppel-like factor 6 suppresses growth and invasion of hepatocellular carcinoma cells in vitro and in vivo. | ||||||||||
| Author: | Wen, Pei-Hao|Wang, Dong-Yu|Zhang, Jia-Kai|Wang, Zhi-Hui|Pan, Jie|Shi, Xiao-Yi|Yang, Han|Zhang, Shui-Jun|Guo, Wen-Zhi | ||||||||||
| PMID: | 27510817 | ||||||||||
| 33. | |||||||||||
| Journal: | Cancer Cell Int. 2017 May 30;17:59. | ||||||||||
| Title: | Berberine regulates the protein expression of multiple tumorigenesis-related genes in hepatocellular carcinoma cell lines. | ||||||||||
| Author: | Chuang, Tung-Yueh|Wu, Hsiao-Li|Min, Jie|Diamond, Michael|Azziz, Ricardo|Chen, Yen-Hao | ||||||||||
| PMID: | 28572744 | ||||||||||
| 34. | |||||||||||
| Journal: | Sci Rep. 2017 Jun 21;7(1):3989. | ||||||||||
| Title: | Platelet releasates promote the proliferation of hepatocellular carcinoma cells by suppressing the expression of KLF6. | ||||||||||
| Author: | He, Ao-Di|Xie, Wen|Song, Wei|Ma, Yuan-Yuan|Liu, Gang|Liang, Ming-Lu|Da, Xing-Wen|Yao, Guang-Qiang|Zhang, Bi-Xiang|Gao, Cun-Ji|Xiang, Ji-Zhou|Ming, Zhang-Yin | ||||||||||
| PMID: | 28638139 | ||||||||||
| 35. | |||||||||||
| Journal: | Sci Rep. 2017 Aug 14;7(1):8119. | ||||||||||
| Title: | Kruppel-like factor 6 is a transcriptional activator of autophagy in acute liver injury. | ||||||||||
| Author: | Sydor, Svenja|Manka, Paul|Best, Jan|Jafoui, Sami|Sowa, Jan-Peter|Zoubek, Miguel Eugenio|Hernandez-Gea, Virginia|Cubero, Francisco Javier|Kalsch, Julia|Vetter, Diana|Fiel, Maria Isabel|Hoshida, Yujin|Bian, C Billie|Nelson, Leonard J|Moshage, Han|Faber, Kla | ||||||||||
| PMID: | 28808340 | ||||||||||