Primary Site >> Colorectal Cancer
Gene >> KLF5
| 1. | |||||||||||
| Journal: | FEBS Lett. 2004 Dec 3;578(1-2):99-105. | ||||||||||
| Title: | All-trans retinoic acid inhibits proliferation of intestinal epithelial cells by inhibiting expression of the gene encoding Kruppel-like factor 5. | ||||||||||
| Author: | Chanchevalap, Sengthong|Nandan, Mandayam O|Merlin, Didier|Yang, Vincent W | ||||||||||
| PMID: | 15581624 | ||||||||||
| 2. | |||||||||||
| Journal: | J Biol Chem. 2004 Mar 26;279(13):12093-101. Epub 2004 Jan 15. | ||||||||||
| Title: | Intestinal tumor progression is associated with altered function of KLF5. | ||||||||||
| Author: | Bateman, Nicholas W|Tan, Dongfeng|Pestell, Richard G|Black, Jennifer D|Black, Adrian R | ||||||||||
| PMID: | 14726538 | ||||||||||
| 3. | |||||||||||
| Journal: | J Nutr. 2005 Aug;135(8):1865-72. | ||||||||||
| Title: | Transcriptome analysis of human colon Caco-2 cells exposed to sulforaphane. | ||||||||||
| Author: | Traka, Maria|Gasper, Amy V|Smith, Julie A|Hawkey, Chris J|Bao, Yongping|Mithen, Richard F | ||||||||||
| PMID: | 16046710 | ||||||||||
| 4. | |||||||||||
| Journal: | Mol Ther. 2007 Jan;15(1):94-102. | ||||||||||
| Title: | Identification of differentially expressed genes involved in the formation of multicellular tumor spheroids by HT-29 colon carcinoma cells. | ||||||||||
| Author: | Dardousis, Kleomenis|Voolstra, Chris|Roengvoraphoj, Monic|Sekandarzad, Asieb|Mesghenna, Senait|Winkler, Johannes|Ko, Yon|Hescheler, Jurgen|Sachinidis, Agapios | ||||||||||
| PMID: | 17164780 | ||||||||||
| 5. | |||||||||||
| Journal: | J Biol Chem. 2007 May 25;282(21):15541-9. Epub 2007 Apr 12. | ||||||||||
| Title: | Lysophosphatidic acid facilitates proliferation of colon cancer cells via induction of Kruppel-like factor 5. | ||||||||||
| Author: | Zhang, Huanchun|Bialkowska, Agnieszka|Rusovici, Raluca|Chanchevalap, Sengthong|Shim, Hyunsuk|Katz, Jonathan P|Yang, Vincent W|Yun, C Chris | ||||||||||
| PMID: | 17430902 | ||||||||||
| 6. | |||||||||||
| Journal: | Gastroenterology. 2008 Jan;134(1):120-30. Epub 2007 Oct 17. | ||||||||||
| Title: | Kruppel-like factor 5 mediates cellular transformation during oncogenic KRAS-induced intestinal tumorigenesis. | ||||||||||
| Author: | Nandan, Mandayam O|McConnell, Beth B|Ghaleb, Amr M|Bialkowska, Agnieszka B|Sheng, Hongmiao|Shao, Jinyi|Babbin, Brian A|Robine, Sylvie|Yang, Vincent W | ||||||||||
| PMID: | 18054006 | ||||||||||
| 7. | |||||||||||
| Journal: | Curr Colorectal Cancer Rep. 2008 Apr;4(2):59-64. | ||||||||||
| Title: | The Pathobiology of Kruppel-like Factors in Colorectal Cancer. | ||||||||||
| Author: | Ghaleb, Amr M|Yang, Vincent W | ||||||||||
| PMID: | 18504508 | ||||||||||
| 8. | |||||||||||
| Journal: | J Biol Chem. 2008 Nov 14;283(46):31991-2002. | ||||||||||
| Title: | SUMOylation regulates nuclear localization of Kruppel-like factor 5. | ||||||||||
| Author: | Du, James X|Bialkowska, Agnieszka B|McConnell, Beth B|Yang, Vincent W | ||||||||||
| PMID: | 18782761 | ||||||||||
| 9. | |||||||||||
| Journal: | Cancer Res. 2009 May 15;69(10):4125-33. | ||||||||||
| Title: | Haploinsufficiency of Kruppel-like factor 5 rescues the tumor-initiating effect of the Apc(Min) mutation in the intestine. | ||||||||||
| Author: | McConnell, Beth B|Bialkowska, Agnieszka B|Nandan, Mandayam O|Ghaleb, Amr M|Gordon, Frank J|Yang, Vincent W | ||||||||||
| PMID: | 19435907 | ||||||||||
| 10. | |||||||||||
| Journal: | Mol Cancer Res. 2009 Aug;7(8):1390-8. | ||||||||||
| Title: | Up-regulation of Kruppel-like factor 5 in pancreatic cancer is promoted by interleukin-1beta signaling and hypoxia-inducible factor-1alpha. | ||||||||||
| Author: | Mori, Akira|Moser, Christian|Lang, Sven A|Hackl, Christina|Gottfried, Eva|Kreutz, Marina|Schlitt, Hans J|Geissler, Edward K|Stoeltzing, Oliver | ||||||||||
| PMID: | 19671674 | ||||||||||
| 11. | |||||||||||
| Journal: | Int J Cancer. 2009 Dec 15;125(12):2802-9. | ||||||||||
| Title: | KLF4-dependent, PPARgamma-induced expression of GPA33 in colon cancer cell lines. | ||||||||||
| Author: | Rageul, Julie|Mottier, Stephanie|Jarry, Anne|Shah, Yatrik|Theoleyre, Sandrine|Masson, Damien|Gonzalez, Frank J|Laboisse, Christian L|Denis, Marc G | ||||||||||
| PMID: | 19551868 | ||||||||||
| 12. | |||||||||||
| Journal: | Gastroenterology. 2009 May;136(5):1711-20. | ||||||||||
| Title: | The absence of LPA2 attenuates tumor formation in an experimental model of colitis-associated cancer. | ||||||||||
| Author: | Lin, Songbai|Wang, Dongsheng|Iyer, Smita|Ghaleb, Amr M|Shim, Hyunsuk|Yang, Vincent W|Chun, Jerold|Yun, C Chris | ||||||||||
| PMID: | 19328876 | ||||||||||
| 13. | |||||||||||
| Journal: | Mol Cancer Ther. 2009 Mar;8(3):563-70. | ||||||||||
| Title: | Identification of novel small-molecule compounds that inhibit the proproliferative Kruppel-like factor 5 in colorectal cancer cells by high-throughput screening. | ||||||||||
| Author: | Bialkowska, Agnieszka B|Du, Yuhong|Fu, Haian|Yang, Vincent W | ||||||||||
| PMID: | 19240162 | ||||||||||
| 14. | |||||||||||
| Journal: | Mol Cancer. 2010 Mar 18;9:63. | ||||||||||
| Title: | Kruppel-like factor 5 is a crucial mediator of intestinal tumorigenesis in mice harboring combined ApcMin and KRASV12 mutations. | ||||||||||
| Author: | Nandan, Mandayam O|Ghaleb, Amr M|McConnell, Beth B|Patel, Nilesh V|Robine, Sylvie|Yang, Vincent W | ||||||||||
| PMID: | 20298593 | ||||||||||
| 15. | |||||||||||
| Journal: | Am J Physiol Gastrointest Liver Physiol. 2010 Nov;299(5):G1128-38. | ||||||||||
| Title: | The absence of LPA receptor 2 reduces the tumorigenesis by ApcMin mutation in the intestine. | ||||||||||
| Author: | Lin, Songbai|Lee, Sei-Jung|Shim, Hyunsuk|Chun, Jerold|Yun, C Chris | ||||||||||
| PMID: | 20724530 | ||||||||||
| 16. | |||||||||||
| Journal: | |||||||||||
| Title: | ML264: An Antitumor Agent that Potently and Selectively Inhibits Kruppel-like Factor Five (KLF5) Expression: A Probe for Studying Colon Cancer Development and Progression | ||||||||||
| Author: | Bialkowska, Agnieszka|Crisp, Melissa|Madoux, Franck|Spicer, Tim|Knapinska, Ania|Mercer, Becky|Bannister, Thomas D.|He, Yuanjun|Chowdhury, Sarwat|Cameron, Michael|Yang, Vincent W.|Hodder, Peter | ||||||||||
| PMID: | 23762940 | ||||||||||
| 17. | |||||||||||
| Journal: | Mol Cancer Ther. 2011 Nov;10(11):2043-51. | ||||||||||
| Title: | Identification of small-molecule inhibitors of the colorectal cancer oncogene Kruppel-like factor 5 expression by ultrahigh-throughput screening. | ||||||||||
| Author: | Bialkowska, Agnieszka B|Crisp, Melissa|Bannister, Thomas|He, Yuanjun|Chowdhury, Sarwat|Schurer, Stephan|Chase, Peter|Spicer, Timothy|Madoux, Franck|Tian, Chenlu|Hodder, Peter|Zaharevitz, Daniel|Yang, Vincent W | ||||||||||
| PMID: | 21885866 | ||||||||||
| 18. | |||||||||||
| Journal: | J Biol Chem. 2013 Aug 30;288(35):25244-53. | ||||||||||
| Title: | Regulation of hypoxia-inducible factor 1alpha (HIF-1alpha) by lysophosphatidic acid is dependent on interplay between p53 and Kruppel-like factor 5. | ||||||||||
| Author: | Lee, Sei-Jung|No, Yi Ran|Dang, Duyen T|Dang, Long H|Yang, Vincent W|Shim, Hyunsuk|Yun, C Chris | ||||||||||
| PMID: | 23880760 | ||||||||||
| 19. | |||||||||||
| Journal: | Cancer Res. 2013 Mar 15;73(6):2003-13. | ||||||||||
| Title: | Genetic amplification of the NOTCH modulator LNX2 upregulates the WNT/beta-catenin pathway in colorectal cancer. | ||||||||||
| Author: | Camps, Jordi|Pitt, Jason J|Emons, Georg|Hummon, Amanda B|Case, Chanelle M|Grade, Marian|Jones, Tamara L|Nguyen, Quang T|Ghadimi, B Michael|Beissbarth, Tim|Difilippantonio, Michael J|Caplen, Natasha J|Ried, Thomas | ||||||||||
| PMID: | 23319804 | ||||||||||
| 20. | |||||||||||
| Journal: | Oncogene. 2013 Oct;32(40):4806-13. | ||||||||||
| Title: | Analysis of the combined action of miR-143 and miR-145 on oncogenic pathways in colorectal cancer cells reveals a coordinate program of gene repression. | ||||||||||
| Author: | Pagliuca, A|Valvo, C|Fabrizi, E|di Martino, S|Biffoni, M|Runci, D|Forte, S|De Maria, R|Ricci-Vitiani, L | ||||||||||
| PMID: | 23128394 | ||||||||||
| 21. | |||||||||||
| Journal: | Gut. 2014 May;63(5):792-9. | ||||||||||
| Title: | Investigation of the atypical FBXW7 mutation spectrum in human tumours by conditional expression of a heterozygous propellor tip missense allele in the mouse intestines. | ||||||||||
| Author: | Davis, Hayley|Lewis, Annabelle|Behrens, Axel|Tomlinson, Ian | ||||||||||
| PMID: | 23676439 | ||||||||||
| 22. | |||||||||||
| Journal: | J Biol Chem. 2014 Feb 28;289(9):5997-6005. | ||||||||||
| Title: | A colon cancer-derived mutant of Kruppel-like factor 5 (KLF5) is resistant to degradation by glycogen synthase kinase 3beta (GSK3beta) and the E3 ubiquitin ligase F-box and WD repeat domain-containing 7alpha (FBW7alpha). | ||||||||||
| Author: | Bialkowska, Agnieszka B|Liu, Yang|Nandan, Mandayam O|Yang, Vincent W | ||||||||||
| PMID: | 24398687 | ||||||||||
| 23. | |||||||||||
| Journal: | Dev Biol. 2014 Mar 15;387(2):191-202. | ||||||||||
| Title: | Inducible intestine-specific deletion of Kruppel-like factor 5 is characterized by a regenerative response in adult mouse colon. | ||||||||||
| Author: | Nandan, Mandayam O|Ghaleb, Amr M|Liu, Yang|Bialkowska, Agnieszka B|McConnell, Beth B|Shroyer, Kenneth R|Robine, Sylvie|Yang, Vincent W | ||||||||||
| PMID: | 24440658 | ||||||||||
| 24. | |||||||||||
| Journal: | J Biol Chem. 2014 Sep 5;289(36):25306-16. | ||||||||||
| Title: | The intestinal epithelial cell differentiation marker intestinal alkaline phosphatase (ALPi) is selectively induced by histone deacetylase inhibitors (HDACi) in colon cancer cells in a Kruppel-like factor 5 (KLF5)-dependent manner. | ||||||||||
| Author: | Shin, Joongho|Carr, Azadeh|Corner, Georgia A|Togel, Lars|Davalos-Salas, Mercedes|Tran, Hoanh|Chueh, Anderly C|Al-Obaidi, Sheren|Chionh, Fiona|Ahmed, Naseem|Buchanan, Daniel D|Young, Joanne P|Malo, Madhu S|Hodin, Richard A|Arango, Diego|Sieber, Oliver M|Au | ||||||||||
| PMID: | 25037223 | ||||||||||
| 25. | |||||||||||
| Journal: | Cell Signal. 2015 May;27(5):961-8. | ||||||||||
| Title: | Kruppel-like factor 5 incorporates into the beta-catenin/TCF complex in response to LPA in colon cancer cells. | ||||||||||
| Author: | Guo, Leilei|He, Peijian|No, Yi Ran|Yun, C Chris | ||||||||||
| PMID: | 25683913 | ||||||||||
| 26. | |||||||||||
| Journal: | J Biol Chem. 2015 Jun 19;290(25):15392. | ||||||||||
| Title: | The intestinal epithelial cell differentiation marker intestinal alkaline phosphatase (ALPi) is selectively induced by histone deacetylase inhibitors (HDACi) in colon cancer cells in a Kruppel-like factor 5 (KLF5)-dependent manner. | ||||||||||
| Author: | Shin, Joongho|Carr, Azadeh|Corner, Georgia A|Togel, Lars|Davalos-Salas, Mercedes|Tran, Hoanh|Chueh, Anderly C|Al-Obaidi, Sheren|Chionh, Fiona|Ahmed, Naseem|Buchanan, Daniel D|Young, Joanne P|Malo, Madhu S|Hodin, Richard A|Arango, Diego|Sieber, Oliver M|Au | ||||||||||
| PMID: | 26092983 | ||||||||||
| 27. | |||||||||||
| Journal: | Cancer Epidemiol Biomarkers Prev. 2015 Nov;24(11):1774-80. | ||||||||||
| Title: | Two novel variants on 13q22.1 are associated with risk of esophageal squamous cell carcinoma. | ||||||||||
| Author: | Chang, Jiang|Wei, Lixuan|Miao, Xiaoping|Yu, Dianke|Tan, Wen|Zhang, Xuemei|Wu, Chen|Lin, Dongxin | ||||||||||
| PMID: | 26315552 | ||||||||||
| 28. | |||||||||||
| Journal: | Oncogene. 2016 Jan 14;35(2):206-17. | ||||||||||
| Title: | DUSP10 regulates intestinal epithelial cell growth and colorectal tumorigenesis. | ||||||||||
| Author: | Png, C W|Weerasooriya, M|Guo, J|James, S J|Poh, H M|Osato, M|Flavell, R A|Dong, C|Yang, H|Zhang, Y | ||||||||||
| PMID: | 25772234 | ||||||||||
| 29. | |||||||||||
| Journal: | Cell Rep. 2016 Apr 26;15(4):857-865. | ||||||||||
| Title: | Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma. | ||||||||||
| Author: | Giannakis, Marios|Mu, Xinmeng Jasmine|Shukla, Sachet A|Qian, Zhi Rong|Cohen, Ofir|Nishihara, Reiko|Bahl, Samira|Cao, Yin|Amin-Mansour, Ali|Yamauchi, Mai|Sukawa, Yasutaka|Stewart, Chip|Rosenberg, Mara|Mima, Kosuke|Inamura, Kentaro|Nosho, Katsuhiko|Nowak, J | ||||||||||
| PMID: | 27149842 | ||||||||||
| 30. | |||||||||||
| Journal: | Mol Cancer Ther. 2016 Jan;15(1):72-83. | ||||||||||
| Title: | ML264, A Novel Small-Molecule Compound That Potently Inhibits Growth of Colorectal Cancer. | ||||||||||
| Author: | Ruiz de Sabando, Ainara|Wang, Chao|He, Yuanjun|Garcia-Barros, Monica|Kim, Julie|Shroyer, Kenneth R|Bannister, Thomas D|Yang, Vincent W|Bialkowska, Agnieszka B | ||||||||||
| PMID: | 26621868 | ||||||||||
| 31. | |||||||||||
| Journal: | Theranostics. 2017 Jun 11;7(8):2339-2349. | ||||||||||
| Title: | YD277 Suppresses Triple-Negative Breast Cancer Partially Through Activating the Endoplasmic Reticulum Stress Pathway. | ||||||||||
| Author: | Chen, Zekun|Wu, Qiuju|Ding, Ye|Zhou, Wenhui|Liu, Rong|Chen, Haiying|Zhou, Jia|Feng, Jing|Chen, Ceshi | ||||||||||
| PMID: | 28740556 | ||||||||||
| 32. | |||||||||||
| Journal: | Oncotarget. 2017 Nov 27;8(65):109301-109318. | ||||||||||
| Title: | Ascl2 activation by YAP1/KLF5 ensures the self-renewability of colon cancer progenitor cells. | ||||||||||
| Author: | Wei, Xiaolong|Ye, Jun|Shang, Yangyang|Chen, Haoyuan|Liu, Shanxi|Liu, Li|Wang, Rongquan | ||||||||||
| PMID: | 29312609 | ||||||||||
| 33. | |||||||||||
| Journal: | Cancer Discov. 2018 Jan;8(1):108-125. | ||||||||||
| Title: | Somatic Superenhancer Duplications and Hotspot Mutations Lead to Oncogenic Activation of the KLF5 Transcription Factor. | ||||||||||
| Author: | Zhang, Xiaoyang|Choi, Peter S|Francis, Joshua M|Gao, Galen F|Campbell, Joshua D|Ramachandran, Aruna|Mitsuishi, Yoichiro|Ha, Gavin|Shih, Juliann|Vazquez, Francisca|Tsherniak, Aviad|Taylor, Alison M|Zhou, Jin|Wu, Zhong|Berger, Ashton C|Giannakis, Marios|Hah | ||||||||||
| PMID: | 28963353 | ||||||||||
| 34. | |||||||||||
| Journal: | Carcinogenesis. 2018 May 3;39(5):652-660. | ||||||||||
| Title: | GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12. | ||||||||||
| Author: | Tanikawa, Chizu|Kamatani, Yoichiro|Takahashi, Atsushi|Momozawa, Yukihide|Leveque, Karine|Nagayama, Satoshi|Mimori, Koshi|Mori, Masaki|Ishii, Hideshi|Inazawa, Johji|Yasuda, Jun|Tsuboi, Akito|Shimizu, Atsushi|Sasaki, Makoto|Yamaji, Taiki|Sawada, Norie|Iwasa | ||||||||||
| PMID: | 29471430 | ||||||||||
| 35. | |||||||||||
| Journal: | Am J Cancer Res. 2018 Apr 1;8(4):723-731. eCollection 2018. | ||||||||||
| Title: | KLF5 mediates the hyper-proliferative phenotype of the intestinal epithelium in mice with intestine-specific endogenous K-Ras(G12D) expression. | ||||||||||
| Author: | Nandan, Mandayam O|Bialkowska, Agnieszka B|Yang, Vincent W | ||||||||||
| PMID: | 29736317 | ||||||||||
| 36. | |||||||||||
| Journal: | J Diabetes Res. 2018 Sep 9;2018:3274084. | ||||||||||
| Title: | Advanced Glycation End Products Increase MDM2 Expression via Transcription Factor KLF5. | ||||||||||
| Author: | Wang, Pu|Lu, Yu Cheng|Li, Yuan Fei|Wang, Lan|Lee, Shao Chin | ||||||||||
| PMID: | 30271790 | ||||||||||