Primary Site >> Liver Cancer
Gene >> KLF4
| 1. | |||||||||||
| Journal: | Cell Transplant. 2011;20(1):15-9. | ||||||||||
| Title: | Induced pluripotent stem (iPS) cell research overview. | ||||||||||
| Author: | Liu, Shih-Ping|Fu, Ru-Huei|Huang, Yu-Chuen|Chen, Shih-Yin|Chien, Ying-Jiun|Hsu, Chien Yu|Tsai, Chang-Hai|Shyu, Woei-Cherng|Lin, Shinn-Zong | ||||||||||
| PMID: | 20887681 | ||||||||||
| 2. | |||||||||||
| Journal: | Oncol Rep. 2012 Jun;27(6):1865-72. | ||||||||||
| Title: | Tumorigenicity of cancer stem-like cells derived from hepatocarcinoma is regulated by microRNA-145. | ||||||||||
| Author: | Jia, Yongsheng|Liu, Honglin|Zhuang, Qianshu|Xu, Shiqing|Yang, Zhihua|Li, Jianzhong|Lou, Jinning|Zhang, Wenjian | ||||||||||
| PMID: | 22378186 | ||||||||||
| 3. | |||||||||||
| Journal: | Gastroenterology. 2012 Sep;143(3):799-810.e2. | ||||||||||
| Title: | Dysregulated Kruppel-like factor 4 and vitamin D receptor signaling contribute to progression of hepatocellular carcinoma. | ||||||||||
| Author: | Li, Qi|Gao, Yong|Jia, Zhiliang|Mishra, Lopa|Guo, Kun|Li, Zhiwei|Le, Xiangdong|Wei, Daoyan|Huang, Suyun|Xie, Keping | ||||||||||
| PMID: | 22677193 | ||||||||||
| 4. | |||||||||||
| Journal: | PLoS One. 2012;7(8):e43593. | ||||||||||
| Title: | Kruppel-like factor 4, a tumor suppressor in hepatocellular carcinoma cells reverts epithelial mesenchymal transition by suppressing slug expression. | ||||||||||
| Author: | Lin, Ze-Shiang|Chu, Hsiao-Chien|Yen, Yi-Chen|Lewis, Brian C|Chen, Ya-Wen | ||||||||||
| PMID: | 22937066 | ||||||||||
| 5. | |||||||||||
| Journal: | Cell Cycle. 2013 Jan 15;12(2):353-64. | ||||||||||
| Title: | The involvement of a Nanog, Klf4 and c-Myc transcriptional circuitry in the intertwining between neoplastic progression and reprogramming. | ||||||||||
| Author: | Marzi, Ilaria|Cipolleschi, Maria Grazia|D'Amico, Massimo|Stivarou, Theodora|Rovida, Elisabetta|Vinci, Maria Cristina|Pandolfi, Silvia|Dello Sbarba, Persio|Stecca, Barbara|Olivotto, Massimo | ||||||||||
| PMID: | 23287475 | ||||||||||
| 6. | |||||||||||
| Journal: | Oncol Lett. 2013 Apr;5(4):1155-1162. | ||||||||||
| Title: | The clinical and prognostic implications of pluripotent stem cell gene expression in hepatocellular carcinoma. | ||||||||||
| Author: | Yin, Xin|Li, Yi-Wei|Jin, Jian-Jun|Zhou, Yin|Ren, Zheng-Gang|Qiu, Shuang-Jian|Zhang, Bo-Heng | ||||||||||
| PMID: | 23599755 | ||||||||||
| 7. | |||||||||||
| Journal: | PLoS One. 2013 Sep 4;8(9):e72435. | ||||||||||
| Title: | Epigenetic regulation of pluripotent genes mediates stem cell features in human hepatocellular carcinoma and cancer cell lines. | ||||||||||
| Author: | Wang, Xiao Qi|Ng, Ray Kit|Ming, Xiaoyan|Zhang, Wu|Chen, Lin|Chu, Andrew C Y|Pang, Roberta|Lo, Chung Mau|Tsao, Sai Wah|Liu, Xuqing|Poon, Ronnie T P|Fan, Sheung Tat | ||||||||||
| PMID: | 24023739 | ||||||||||
| 8. | |||||||||||
| Journal: | World J Gastroenterol. 2013 Dec 21;19(47):8850-60. | ||||||||||
| Title: | Cellular reprogramming and hepatocellular carcinoma development. | ||||||||||
| Author: | Zheng, Yun-Wen|Nie, Yun-Zhong|Taniguchi, Hideki | ||||||||||
| PMID: | 24379607 | ||||||||||
| 9. | |||||||||||
| Journal: | Tumour Biol. 2015 Feb;36(2):533-41. | ||||||||||
| Title: | Kruppel-like factors in hepatocellular carcinoma. | ||||||||||
| Author: | Lu, Xiao-Jie|Shi, Yan|Chen, Jin-Lian|Ma, Shijie | ||||||||||
| PMID: | 25652467 | ||||||||||
| 10. | |||||||||||
| Journal: | Int J Oncol. 2015 Oct;47(4):1554-62. | ||||||||||
| Title: | Identification of a non-coding KLF4 transcript generated from intron retention and downregulated in human hepatocellular carcinoma. | ||||||||||
| Author: | Zhou, Junwei|Lai, Paul Bo-San|Tsui, Stephen Kwok-Wing | ||||||||||
| PMID: | 26238073 | ||||||||||
| 11. | |||||||||||
| Journal: | Oncotarget. 2015 Nov 10;6(35):37200-15. | ||||||||||
| Title: | Plasma DCLK1 is a marker of hepatocellular carcinoma (HCC): Targeting DCLK1 prevents HCC tumor xenograft growth via a microRNA-dependent mechanism. | ||||||||||
| Author: | Sureban, Sripathi M|Madhoun, Mohammad F|May, Randal|Qu, Dongfeng|Ali, Naushad|Fazili, Javid|Weygant, Nathaniel|Chandrakesan, Parthasarathy|Ding, Kai|Lightfoot, Stanley A|Houchen, Courtney W | ||||||||||
| PMID: | 26468984 | ||||||||||
| 12. | |||||||||||
| Journal: | Oncotarget. 2015 Dec 29;6(42):44452-65. | ||||||||||
| Title: | Knock out CD44 in reprogrammed liver cancer cell C3A increases CSCs stemness and promotes differentiation. | ||||||||||
| Author: | Han, Shuo|Guo, Jinhai|Liu, Yinan|Zhang, Zhi|He, Qihua|Li, Peng|Zhang, Mingzhi|Sun, Haojie|Li, Ruizhi|Li, Yang|Zeng, Wotan|Liu, Jinwen|Lian, Lejian|Gao, Yi|Shen, Li | ||||||||||
| PMID: | 26540347 | ||||||||||
| 13. | |||||||||||
| Journal: | Oncol Rep. 2016 Mar;35(3):1657-63. | ||||||||||
| Title: | TALEN-induced disruption of Nanog expression results in reduced proliferation, invasiveness and migration, increased chemosensitivity and reversal of EMT in HepG2 cells. | ||||||||||
| Author: | Yu, Ai Qing|Ding, Yan|Li, Cheng Lin|Yang, Yi|Yan, Shi Rong|Li, Dong Sheng | ||||||||||
| PMID: | 26676719 | ||||||||||
| 14. | |||||||||||
| Journal: | Sci Rep. 2016 Oct 11;6:34856. | ||||||||||
| Title: | Hepatocellular Carcinoma-propagating Cells are Detectable by Side Population Analysis and Possess an Expression Profile Reflective of a Primitive Origin. | ||||||||||
| Author: | Xia, Honghai|Cao, Jun|Li, Qing|Lv, Yang|Jia, Weidong|Ren, Weihua|Cheng, Qingyu|Song, Xiaoyuan|Xu, Geliang | ||||||||||
| PMID: | 27725724 | ||||||||||
| 15. | |||||||||||
| Journal: | Oncotarget. 2016 Nov 1;7(44):71309-71329. | ||||||||||
| Title: | Restoring miR122 in human stem-like hepatocarcinoma cells, prompts tumor dormancy through Smad-independent TGF-beta pathway. | ||||||||||
| Author: | Boix, Loreto|Lopez-Oliva, Juan Manuel|Rhodes, Ana Carolina|Bruix, Jordi | ||||||||||
| PMID: | 27612430 | ||||||||||
| 16. | |||||||||||
| Journal: | Tumour Biol. 2016 Oct;37(10):14103-14115. | ||||||||||
| Title: | Arsenite inhibits the function of CD133(+) CD13(+) liver cancer stem cells by reducing PML and Oct4 protein expression. | ||||||||||
| Author: | Tang, Huaming|Jin, Yukai|Jin, Shilong|Tan, Zhiming|Peng, Zhang|Kuang, Yuanli | ||||||||||
| PMID: | 27517564 | ||||||||||
| 17. | |||||||||||
| Journal: | Am J Physiol Gastrointest Liver Physiol. 2016 Jul 1;311(1):G91-G104. | ||||||||||
| Title: | Bile acids promote diethylnitrosamine-induced hepatocellular carcinoma via increased inflammatory signaling. | ||||||||||
| Author: | Sun, Lina|Beggs, Kevin|Borude, Prachi|Edwards, Genea|Bhushan, Bharat|Walesky, Chad|Roy, Nairita|Manley, Michael W Jr|Gunewardena, Sumedha|O'Neil, Maura|Li, Hua|Apte, Udayan | ||||||||||
| PMID: | 27151938 | ||||||||||
| 18. | |||||||||||
| Journal: | J Transl Med. 2016 Feb 12;14:49. | ||||||||||
| Title: | Detection of ALDH1 activity in rabbit hepatic VX2 tumors and isolation of ALDH1 positive cancer stem cells. | ||||||||||
| Author: | Gehlot, Prashasnika|Shukla, Vivek|Gupta, Sanjay|Makidon, Paul E | ||||||||||
| PMID: | 26873175 | ||||||||||
| 19. | |||||||||||
| Journal: | Gut Liver. 2017 Mar 15;11(2):261-269. | ||||||||||
| Title: | Establishment of Hepatocellular Cancer Induced Pluripotent Stem Cells Using a Reprogramming Technique. | ||||||||||
| Author: | Kim, Han Joon|Jeong, Jaemin|Park, Sunhoo|Jin, Young-Woo|Lee, Seung-Sook|Lee, Seung Bum|Choi, Dongho | ||||||||||
| PMID: | 27728962 | ||||||||||
| 20. | |||||||||||
| Journal: | Stud Health Technol Inform. 2017;245:667-671. | ||||||||||
| Title: | Identifying Biomarkers of Hepatocellular Carcinoma Based on Gene Co-Expression Network from High-Throughput Data. | ||||||||||
| Author: | Zhang, Ying|Liu, Zhiping|Li, Jing-Song | ||||||||||
| PMID: | 29295180 | ||||||||||
| 21. | |||||||||||
| Journal: | BMC Cancer. 2017 Dec 18;17(1):862. | ||||||||||
| Title: | Gene expression, regulation of DEN and HBx induced HCC mice models and comparisons of tumor, para-tumor and normal tissues. | ||||||||||
| Author: | Tang, Qin|Wang, Qi|Zhang, Qiong|Lin, Sheng-Yan|Zhu, Yanhong|Yang, Xiangliang|Guo, An-Yuan | ||||||||||
| PMID: | 29254483 | ||||||||||
| 22. | |||||||||||
| Journal: | Artif Cells Nanomed Biotechnol. 2017 Dec 18:1-9. | ||||||||||
| Title: | miR-124 inhibits progression of hepatocarcinoma by targeting KLF4 and promises a novel diagnostic marker. | ||||||||||
| Author: | Wu, Li-Pei|Wu, Jian|Shang, Anquan|Yang, Man|Li, Ling-Ling|Yu, Jing|Xu, Lei-Rong|Wang, Chun-Bing|Wang, Wei-Wei|Zhu, Jian-Jun|Lu, Wen-Ying | ||||||||||
| PMID: | 29252002 | ||||||||||
| 23. | |||||||||||
| Journal: | World J Stem Cells. 2017 Sep 26;9(9):159-168. | ||||||||||
| Title: | Murine hepatocellular carcinoma derived stem cells reveal epithelial-to-mesenchymal plasticity. | ||||||||||
| Author: | Jayachandran, Aparna|Shrestha, Ritu|Dhungel, Bijay|Huang, I-Tao|Vasconcelos, Marianna Yumi Kawashima|Morrison, Brian J|Ramlogan-Steel, Charmaine A|Steel, Jason C | ||||||||||
| PMID: | 29026462 | ||||||||||
| 24. | |||||||||||
| Journal: | Oncotarget. 2017 Jul 17;8(40):68263-68269. | ||||||||||
| Title: | MicroRNA-18a promotes proliferation and metastasis in hepatocellular carcinoma via targeting KLF4. | ||||||||||
| Author: | Liu, Li|Cai, Xun|Liu, Enqiang|Tian, Xia|Tian, Chuan | ||||||||||
| PMID: | 28978114 | ||||||||||
| 25. | |||||||||||
| Journal: | Cancer Lett. 2017 Aug 1;400:149-160. | ||||||||||
| Title: | Hepatitis B virus PreS1 facilitates hepatocellular carcinoma development by promoting appearance and self-renewal of liver cancer stem cells. | ||||||||||
| Author: | Liu, Zhixin|Dai, Xuechen|Wang, Tianci|Zhang, Chengcheng|Zhang, Wenjun|Zhang, Wei|Zhang, Qi|Wu, Kailang|Liu, Fang|Liu, Yingle|Wu, Jianguo | ||||||||||
| PMID: | 28455240 | ||||||||||
| 26. | |||||||||||
| Journal: | J Biol Chem. 2017 Feb 10;292(6):2143-2158. | ||||||||||
| Title: | RYBP Expression Is Regulated by KLF4 and Sp1 and Is Related to Hepatocellular Carcinoma Prognosis. | ||||||||||
| Author: | Zhao, Qiaojiajie|Cai, Weihua|Zhang, Xuan|Tian, Shuo|Zhang, Junwen|Li, Haibo|Hou, Congcong|Ma, Xiaoli|Chen, Hong|Huang, Bingren|Chen, Deng | ||||||||||
| PMID: | 28028181 | ||||||||||
| 27. | |||||||||||
| Journal: | Int J Cancer. 2017 Mar 15;140(6):1346-1355. | ||||||||||
| Title: | HBx drives alpha fetoprotein expression to promote initiation of liver cancer stem cells through activating PI3K/AKT signal pathway. | ||||||||||
| Author: | Zhu, Mingyue|Li, Wei|Lu, Yan|Dong, Xu|Lin, Bo|Chen, Yi|Zhang, Xueer|Guo, Junli|Li, Mengsen | ||||||||||
| PMID: | 27925189 | ||||||||||
| 28. | |||||||||||
| Journal: | Int J Mol Med. 2017 Jan;39(1):47-56. | ||||||||||
| Title: | Klf4 inhibits tumor growth and metastasis by targeting microRNA-31 in human hepatocellular carcinoma. | ||||||||||
| Author: | Tian, Chuan|Yao, Shanshan|Liu, Li|Ding, Youcheng|Ye, Qingwang|Dong, Xiao|Gao, Yong|Yang, Ning|Li, Qi | ||||||||||
| PMID: | 27909734 | ||||||||||
| 29. | |||||||||||
| Journal: | Oncotarget. 2017 Jan 24;8(4):6067-6078. | ||||||||||
| Title: | MBD3 inhibits formation of liver cancer stem cells. | ||||||||||
| Author: | Li, Ruizhi|He, Qihua|Han, Shuo|Zhang, Mingzhi|Liu, Jinwen|Su, Ming|Wei, Shiruo|Wang, Xuan|Shen, Li | ||||||||||
| PMID: | 27894081 | ||||||||||
| 30. | |||||||||||
| Journal: | Hepatology. 2018 Apr;67(4):1360-1377. | ||||||||||
| Title: | Barrier to autointegration factor 1, procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3, and splicing factor 3b subunit 4 as early-stage cancer decision markers and drivers of hepatocellular carcinoma. | ||||||||||
| Author: | Shen, Qingyu|Eun, Jung Woo|Lee, Kyungbun|Kim, Hyung Seok|Yang, Hee Doo|Kim, Sang Yean|Lee, Eun Kyung|Kim, Taemook|Kang, Keunsoo|Kim, Seongchan|Min, Dal-Hee|Oh, Soon-Nam|Lee, Young-Joon|Moon, Hyuk|Ro, Simon Weonsang|Park, Won Sang|Lee, Jung Young|Nam, Suk | ||||||||||
| PMID: | 29059470 | ||||||||||
| 31. | |||||||||||
| Journal: | Cancer Cell Int. 2018 Jan 17;18:10. | ||||||||||
| Title: | MicroRNA-10b regulates epithelial-mesenchymal transition by modulating KLF4/KLF11/Smads in hepatocellular carcinoma. | ||||||||||
| Author: | Hujie, Gulibaha|Zhou, Sheng-Hua|Zhang, Hua|Qu, Jie|Xiong, Xiao-Wei|Hujie, Outikuer|Liao, Cheng-Gong|Yang, Shun-E | ||||||||||
| PMID: | 29375271 | ||||||||||
| 32. | |||||||||||
| Journal: | BMB Rep. 2018 Feb;51(2):57-58. | ||||||||||
| Title: | SF3B4 as an early-stage diagnostic marker and driver of hepatocellular carcinoma. | ||||||||||
| Author: | Shen, Qingyu|Nam, Suk Woo | ||||||||||
| PMID: | 29397868 | ||||||||||
| 33. | |||||||||||
| Journal: | Exp Mol Pathol. 2018 Apr;104(2):125-129. | ||||||||||
| Title: | Expression of proteins upregulated in hepatocellular carcinoma in patients with alcoholic hepatitis (AH) compared to non-alcoholic steatohepatitis (NASH): An immunohistochemical analysis of candidate proteins. | ||||||||||
| Author: | Lu, Jiajie George|Nguyen, Luan|Samadzadeh, Sara|Masouminia, Maryam|Mendoza, Alejandro|Sweeney, Owen|Tillman, Brittany|Afifyan, Nikoo|Morgan, Timothy|French, Barbara A|French, Samuel W | ||||||||||
| PMID: | 29425759 | ||||||||||
| 34. | |||||||||||
| Journal: | Oncotarget. 2017 Nov 20;9(15):12471-12478. | ||||||||||
| Title: | Research progress on the forkhead box C1. | ||||||||||
| Author: | Wang, Jinhua|Li, Wan|Zheng, Xiangjin|Pang, Xiaocong|Du, Guanhua | ||||||||||
| PMID: | 29552326 | ||||||||||
| 35. | |||||||||||
| Journal: | Eur J Pharmacol. 2018 Aug 5;832:39-49. | ||||||||||
| Title: | Combined treatment with sorafenib and silibinin synergistically targets both HCC cells and cancer stem cells by enhanced inhibition of the phosphorylation of STAT3/ERK/AKT. | ||||||||||
| Author: | Mao, Jie|Yang, Hongbao|Cui, Tingting|Pan, Pan|Kabir, Nadia|Chen, Duo|Ma, Jinyan|Chen, Xingyi|Chen, Yijun|Yang, Yong | ||||||||||
| PMID: | 29782854 | ||||||||||
| 36. | |||||||||||
| Journal: | Oncol Rep. 2018 Sep;40(3):1657-1665. | ||||||||||
| Title: | Homeobox containing 1 inhibits liver cancer progression by promoting autophagy as well as inhibiting stemness and immune escape. | ||||||||||
| Author: | Zhao, Hengli|Jia, Huifeng|Han, Qiuju|Zhang, Jian | ||||||||||
| PMID: | 30015890 | ||||||||||
| 37. | |||||||||||
| Journal: | Am J Cancer Res. 2018 Jun 1;8(6):1019-1029. eCollection 2018. | ||||||||||
| Title: | KLF4 suppresses the migration of hepatocellular carcinoma by transcriptionally upregulating monoglyceride lipase. | ||||||||||
| Author: | Yang, Xuejun|Zhang, Dongmei|Liu, Sha|Li, Xiaojie|Hu, Wanglai|Han, Chuanchun | ||||||||||
| PMID: | 30034939 | ||||||||||