Primary Site >> Liver Cancer
Gene >> KLF4
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Ref: Induced pluripotent stem (iPS) cell research overview. PMID: 20887681 |
Ref: Tumorigenicity of cancer stem-like cells derived from hepatocarcinoma is regulated by microRNA-145. PMID: 22378186 Ref: Dysregulated Kruppel-like factor 4 and vitamin D receptor signaling contribute to progression of hepatocellular carcinoma. PMID: 22677193 Ref: Kruppel-like factor 4, a tumor suppressor in hepatocellular carcinoma cells reverts epithelial mesenchymal transition by suppressing slug expression. PMID: 22937066 |
Ref: The involvement of a Nanog, Klf4 and c-Myc transcriptional circuitry in the intertwining between neoplastic progression and reprogramming. PMID: 23287475 Ref: The clinical and prognostic implications of pluripotent stem cell gene expression in hepatocellular carcinoma. PMID: 23599755 Ref: Epigenetic regulation of pluripotent genes mediates stem cell features in human hepatocellular carcinoma and cancer cell lines. PMID: 24023739 Ref: Cellular reprogramming and hepatocellular carcinoma development. PMID: 24379607 |
Ref: Kruppel-like factors in hepatocellular carcinoma. PMID: 25652467 Ref: Identification of a non-coding KLF4 transcript generated from intron retention and downregulated in human hepatocellular carcinoma. PMID: 26238073 Ref: Plasma DCLK1 is a marker of hepatocellular carcinoma (HCC): Targeting DCLK1 prevents HCC tumor xenograft growth via a microRNA-dependent mechanism. PMID: 26468984 Ref: Knock out CD44 in reprogrammed liver cancer cell C3A increases CSCs stemness and promotes differentiation. PMID: 26540347 |
Ref: TALEN-induced disruption of Nanog expression results in reduced proliferation, invasiveness and migration, increased chemosensitivity and reversal of EMT in HepG2 cells. PMID: 26676719 Ref: Detection of ALDH1 activity in rabbit hepatic VX2 tumors and isolation of ALDH1 positive cancer stem cells. PMID: 26873175 Ref: Bile acids promote diethylnitrosamine-induced hepatocellular carcinoma via increased inflammatory signaling. PMID: 27151938 Ref: Arsenite inhibits the function of CD133(+) CD13(+) liver cancer stem cells by reducing PML and Oct4 protein expression. PMID: 27517564 Ref: Restoring miR122 in human stem-like hepatocarcinoma cells, prompts tumor dormancy through Smad-independent TGF-beta pathway. PMID: 27612430 Ref: Hepatocellular Carcinoma-propagating Cells are Detectable by Side Population Analysis and Possess an Expression Profile Reflective of a Primitive Origin. PMID: 27725724 |
Ref: Establishment of Hepatocellular Cancer Induced Pluripotent Stem Cells Using a Reprogramming Technique. PMID: 27728962 Ref: MBD3 inhibits formation of liver cancer stem cells. PMID: 27894081 Ref: Klf4 inhibits tumor growth and metastasis by targeting microRNA-31 in human hepatocellular carcinoma. PMID: 27909734 Ref: HBx drives alpha fetoprotein expression to promote initiation of liver cancer stem cells through activating PI3K/AKT signal pathway. PMID: 27925189 Ref: RYBP Expression Is Regulated by KLF4 and Sp1 and Is Related to Hepatocellular Carcinoma Prognosis. PMID: 28028181 Ref: Hepatitis B virus PreS1 facilitates hepatocellular carcinoma development by promoting appearance and self-renewal of liver cancer stem cells. PMID: 28455240 Ref: MicroRNA-18a promotes proliferation and metastasis in hepatocellular carcinoma via targeting KLF4. PMID: 28978114 Ref: Murine hepatocellular carcinoma derived stem cells reveal epithelial-to-mesenchymal plasticity. PMID: 29026462 Ref: miR-124 inhibits progression of hepatocarcinoma by targeting KLF4 and promises a novel diagnostic marker. PMID: 29252002 Ref: Gene expression, regulation of DEN and HBx induced HCC mice models and comparisons of tumor, para-tumor and normal tissues. PMID: 29254483 Ref: Identifying Biomarkers of Hepatocellular Carcinoma Based on Gene Co-Expression Network from High-Throughput Data. PMID: 29295180 |
Ref: Barrier to autointegration factor 1, procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3, and splicing factor 3b subunit 4 as early-stage cancer decision markers and drivers of hepatocellular carcinoma. PMID: 29059470 Ref: MicroRNA-10b regulates epithelial-mesenchymal transition by modulating KLF4/KLF11/Smads in hepatocellular carcinoma. PMID: 29375271 Ref: SF3B4 as an early-stage diagnostic marker and driver of hepatocellular carcinoma. PMID: 29397868 Ref: Expression of proteins upregulated in hepatocellular carcinoma in patients with alcoholic hepatitis (AH) compared to non-alcoholic steatohepatitis (NASH): An immunohistochemical analysis of candidate proteins. PMID: 29425759 Ref: Research progress on the forkhead box C1. PMID: 29552326 Ref: Combined treatment with sorafenib and silibinin synergistically targets both HCC cells and cancer stem cells by enhanced inhibition of the phosphorylation of STAT3/ERK/AKT. PMID: 29782854 Ref: Homeobox containing 1 inhibits liver cancer progression by promoting autophagy as well as inhibiting stemness and immune escape. PMID: 30015890 Ref: KLF4 suppresses the migration of hepatocellular carcinoma by transcriptionally upregulating monoglyceride lipase. PMID: 30034939 |