Primary Site >> Colorectal Cancer

Gene >> KLF4

1.
Journal: Biochem J. 2000 Jun 15;348 Pt 3:675-86.
Title: Sequence of the 5'-flanking region and promoter activity of the human mucin gene MUC5B in different phenotypes of colon cancer cells.
Author: Van Seuningen, I|Perrais, M|Pigny, P|Porchet, N|Aubert, J P
PMID: 10840001
2.
Journal: FEBS Lett. 2000 Jul 14;477(1-2):67-72.
Title: Up-regulation of gut-enriched kruppel-like factor by interferon-gamma in human colon carcinoma cells.
Author: Chen, Z Y|Shie, J|Tseng, C
PMID: 10899312
3.
Journal: Nucleic Acids Res. 2000 Aug 1;28(15):2969-76.
Title: Gut-enriched Kruppel-like factor represses cyclin D1 promoter activity through Sp1 motif.
Author: Shie, J L|Chen, Z Y|Fu, M|Pestell, R G|Tseng, C C
PMID: 10908361
4.
Journal: Cancer Res. 2000 Nov 15;60(22):6488-95.
Title: Increase of GKLF messenger RNA and protein expression during progression of breast cancer.
Author: Foster, K W|Frost, A R|McKie-Bell, P|Lin, C Y|Engler, J A|Grizzle, W E|Ruppert, J M
PMID: 11103818
5.
Journal: Biochem Biophys Res Commun. 2001 Apr 27;283(1):205-8.
Title: A nucleus-localization-deficient mutant serves as a dominant-negative inhibitor of gut-enriched Kruppel-like factor function.
Author: Shie, J L|Tseng, C C
PMID: 11322789
6.
Journal: J Biol Chem. 2001 Aug 10;276(32):30423-8.
Title: Kruppel-like factor 4 (gut-enriched Kruppel-like factor) inhibits cell proliferation by blocking G1/S progression of the cell cycle.
Author: Chen, X|Johns, D C|Geiman, D E|Marban, E|Dang, D T|Hamlin, G|Sun, R|Yang, V W
PMID: 11390382
7.
Journal: Oncogene. 2001 Aug 9;20(35):4884-90.
Title: Expression of the gut-enriched Kruppel-like factor (Kruppel-like factor 4) gene in the human colon cancer cell line RKO is dependent on CDX2.
Author: Dang, D T|Mahatan, C S|Dang, L H|Agboola, I A|Yang, V W
PMID: 11521200
8.
Journal: J Biol Chem. 2002 Nov 29;277(48):46831-9. Epub 2002 Sep 23.
Title: Gut-enriched Kruppel-like factor represses ornithine decarboxylase gene expression and functions as checkpoint regulator in colonic cancer cells.
Author: Chen, Zhi Y|Shie, Jue-Lon|Tseng, Chi-Chuan
PMID: 12297499
9.
Journal: FEBS Lett. 2002 Oct 23;530(1-3):147-52.
Title: Gut-enriched Kruppel-like factor regulates colonic cell growth through APC/beta-catenin pathway.
Author: Stone, Christian D|Chen, Zhi Y|Tseng, Chi Chuan
PMID: 12387883
10.
Journal: Exp Cell Res. 2002 Nov 15;281(1):19-27.
Title: STAT1 is required for IFN-gamma-mediated gut-enriched Kruppel-like factor expression.
Author: Chen, Zhi Y|Shie, Jue Lon|Tseng, Chi Chuan
PMID: 12441126
11.
Journal: J Biol Chem. 2003 Jan 24;278(4):2101-5.
Title: Kruppel-like factor 4 mediates p53-dependent G1/S cell cycle arrest in response to DNA damage.
Author: Yoon, Hong S|Chen, Xinming|Yang, Vincent W
PMID: 12427745
12.
Journal: Oncogene. 2003 May 29;22(22):3424-30.
Title: Overexpression of Kruppel-like factor 4 in the human colon cancer cell line RKO leads to reduced tumorigenecity.
Author: Dang, Duyen T|Chen, Xinming|Feng, Jing|Torbenson, Michael|Dang, Long H|Yang, Vincent W
PMID: 12776194
13.
Journal: Oncogene. 2003 Jul 10;22(28):4434-43.
Title: Transcriptional regulation of A33 antigen expression by gut-enriched Kruppel-like factor.
Author: Mao, Zebin|Song, Shan|Zhu, Yunyan|Yi, Xia|Zhang, Hua|Shang, Yongfeng|Tong, Tanjun
PMID: 12853980
14.
Journal: Am J Physiol Gastrointest Liver Physiol. 2004 Jan;286(1):G23-30. Epub 2003 Aug
Title: Enterocyte differentiation marker intestinal alkaline phosphatase is a target gene of the gut-enriched Kruppel-like factor.
Author: Hinnebusch, Brian F|Siddique, Aleem|Henderson, J Welles|Malo, Madhu S|Zhang, Wenying|Athaide, Christopher P|Abedrapo, Mario A|Chen, Xinming|Yang, Vincent W|Hodin, Richard A
PMID: 12919939
15.
Journal: J Biol Chem. 2004 Feb 6;279(6):5035-41.
Title: Requirement of Kruppel-like factor 4 in preventing entry into mitosis following DNA damage.
Author: Yoon, Hong S|Yang, Vincent W
PMID: 14627709
16.
Journal: Oncogene. 2004 Jan 15;23(2):395-402.
Title: Identification of Kruppel-like factor 4 as a potential tumor suppressor gene in colorectal cancer.
Author: Zhao, Weidong|Hisamuddin, Irfan M|Nandan, Mandayam O|Babbin, Brian A|Lamb, Neil E|Yang, Vincent W
PMID: 14724568
17.
Journal: J Biol Chem. 2004 May 21;279(21):22674-83. Epub 2004 Mar 18.
Title: The Kruppel-like KLF4 transcription factor, a novel regulator of urokinase receptor expression, drives synthesis of this binding site in colonic crypt luminal surface epithelial cells.
Author: Wang, Heng|Yang, Lin|Jamaluddin, Md Saha|Boyd, Douglas D
PMID: 15031282
18.
Journal: J Nutr. 2004 Apr;134(4):792-8.
Title: Kruppel-like factor 4 is transactivated by butyrate in colon cancer cells.
Author: Chen, Zhi Yi|Rex, Sybille|Tseng, Chi-Chuan
PMID: 15051827
19.
Journal: Genes Dev. 2005 Feb 1;19(3):362-75.
Title: Hic-5 regulates an epithelial program mediated by PPARgamma.
Author: Drori, Stavit|Girnun, Geoffrey D|Tou, Liqiang|Szwaya, Jeffrey D|Mueller, Elisabetta|Xia, Kai|Shivdasani, Ramesh A|Spiegelman, Bruce M
PMID: 15687259
20.
Journal: Oncogene. 2005 Jun 9;24(25):4017-25.
Title: Kruppel-like factor 4 prevents centrosome amplification following gamma-irradiation-induced DNA damage.
Author: Yoon, Hong S|Ghaleb, Amr M|Nandan, Mandayam O|Hisamuddin, Irfan M|Dalton, William Brian|Yang, Vincent W
PMID: 15806166
21.
Journal: J Nutr. 2005 Aug;135(8):1865-72.
Title: Transcriptome analysis of human colon Caco-2 cells exposed to sulforaphane.
Author: Traka, Maria|Gasper, Amy V|Smith, Julie A|Hawkey, Chris J|Bao, Yongping|Mithen, Richard F
PMID: 16046710
22.
Journal: Mol Pharmacol. 2005 Nov;68(5):1203-13. Epub 2005 Aug 2.
Title: 15-deoxy-Delta12,14 prostaglandin J2 up-regulates Kruppel-like factor 4 expression independently of peroxisome proliferator-activated receptor gamma by activating the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase signal tra
Author: Chen, Zhi Yi|Tseng, Chi-Chuan
PMID: 16077033
23.
Journal: Carcinogenesis. 2006 Jan;27(1):23-31. Epub 2005 Oct 11.
Title: Emerging role of KLF4 in human gastrointestinal cancer.
Author: Wei, Daoyan|Kanai, Masashi|Huang, Suyun|Xie, Keping
PMID: 16219632
24.
Journal: Mol Cell Biol. 2006 Mar;26(6):2055-64.
Title: Novel cross talk of Kruppel-like factor 4 and beta-catenin regulates normal intestinal homeostasis and tumor repression.
Author: Zhang, Wen|Chen, Xi|Kato, Yoichi|Evans, Paul M|Yuan, Subo|Yang, Jun|Rychahou, Piotr G|Yang, Vincent W|He, Xi|Evers, B Mark|Liu, Chunming
PMID: 16507986
25.
Journal: Pathol Res Pract. 2006;202(8):585-9. Epub 2006 Jun 30.
Title: Altered expression of the KLF4 in colorectal cancers.
Author: Choi, Byung Joon|Cho, Yong Gu|Song, Jae Whie|Kim, Chang Jae|Kim, Su Young|Nam, Suk Woo|Yoo, Nam Jin|Lee, Jung Young|Park, Won Sang
PMID: 16814484
26.
Journal: Oncogene. 2007 Apr 5;26(16):2365-73. Epub 2006 Oct 2.
Title: Kruppel-like factor 4 exhibits antiapoptotic activity following gamma-radiation-induced DNA damage.
Author: Ghaleb, A M|Katz, J P|Kaestner, K H|Du, J X|Yang, V W
PMID: 17016435
27.
Journal: Mol Cancer Ther. 2007 May;6(5):1588-98.
Title: Structure-dependent activity of glycyrrhetinic acid derivatives as peroxisome proliferator-activated receptor {gamma} agonists in colon cancer cells.
Author: Chintharlapalli, Sudhakar|Papineni, Sabitha|Jutooru, Indira|McAlees, Alan|Safe, Stephen
PMID: 17513608
28.
Journal: Cancer Res. 2007 Aug 1;67(15):7147-54.
Title: Haploinsufficiency of Kruppel-like factor 4 promotes adenomatous polyposis coli dependent intestinal tumorigenesis.
Author: Ghaleb, Amr M|McConnell, Beth B|Nandan, Mandayam O|Katz, Jonathan P|Kaestner, Klaus H|Yang, Vincent W
PMID: 17671182
29.
Journal: Carcinogenesis. 2007 Nov;28(11):2337-46. Epub 2007 Aug 27.
Title: 2-cyano-lup-1-en-3-oxo-20-oic acid, a cyano derivative of betulinic acid, activates peroxisome proliferator-activated receptor gamma in colon and pancreatic cancer cells.
Author: Chintharlapalli, Sudhakar|Papineni, Sabitha|Liu, Shengxi|Jutooru, Indira|Chadalapaka, Gayathri|Cho, Sung-dae|Murthy, Rajesh S|You, Youngjae|Safe, Stephen
PMID: 17724373
30.
Journal: J Biol Chem. 2007 Nov 23;282(47):33994-4002.
Title: Kruppel-like factor 4 is acetylated by p300 and regulates gene transcription via modulation of histone acetylation.
Author: Evans, Paul M|Zhang, Wen|Chen, Xi|Yang, Jun|Bhakat, Kishor K|Liu, Chunming
PMID: 17908689
31.
Journal: J Cancer Res Clin Oncol. 2008 Aug;134(8):891-8.
Title: Dynamic down-regulation of Kruppel-like factor 4 in colorectal adenoma-carcinoma sequence.
Author: Xu, Jing|Lu, Bingjian|Xu, Fangying|Gu, Hongguang|Fang, Yihu|Huang, Qiong|Lai, Maode
PMID: 18264726
32.
Journal: Cancer Biol Ther. 2008 May;7(5):777-82. Epub 2008 May 20.
Title: Nuclear Kruppel-like factor 4 expression is associated with human skin squamous cell carcinoma progression and metastasis.
Author: Chen, Yi-Ju|Wu, Chun-Ying|Chang, Chia-Che|Ma, Chieh-Ju|Li, Mu-Chun|Chen, Chuan-Mu
PMID: 18376139
33.
Journal: Curr Colorectal Cancer Rep. 2008 Apr;4(2):59-64.
Title: The Pathobiology of Kruppel-like Factors in Colorectal Cancer.
Author: Ghaleb, Amr M|Yang, Vincent W
PMID: 18504508
34.
Journal: Mol Cancer Ther. 2008 Jul;7(7):2109-20.
Title: 5,5'-Dibromo-bis(3'-indolyl)methane induces Kruppel-like factor 4 and p21 in colon cancer cells.
Author: Cho, Sung Dae|Chintharlapalli, Sudhakar|Abdelrahim, Maen|Papineni, Sabitha|Liu, Shengxi|Guo, Jingjing|Lei, Ping|Abudayyeh, Ala|Safe, Stephen
PMID: 18645021
35.
Journal: Exp Cell Res. 2008 Dec 10;314(20):3712-23.
Title: KLF4 regulation in intestinal epithelial cell maturation.
Author: Flandez, M|Guilmeau, S|Blache, P|Augenlicht, L H
PMID: 18977346
36.
Journal: Mol Cancer Res. 2008 Dec;6(12):1920-7.
Title: Notch inhibits expression of the Kruppel-like factor 4 tumor suppressor in the intestinal epithelium.
Author: Ghaleb, Amr M|Aggarwal, Gaurav|Bialkowska, Agnieszka B|Nandan, Mandayam O|Yang, Vincent W
PMID: 19074836
37.
Journal: Am J Physiol Gastrointest Liver Physiol. 2009 Mar;296(3):G490-8.
Title: KLF4 gene expression is inhibited by the notch signaling pathway that controls goblet cell differentiation in mouse gastrointestinal tract.
Author: Zheng, Hai|Pritchard, D Mark|Yang, Xiangdong|Bennett, Elaine|Liu, Gang|Liu, Chunming|Ai, Walden
PMID: 19109406
38.
Journal: Nutr Cancer. 2009;61(1):137-45.
Title: Involvement of KLF4 in sulforaphane- and iberin-mediated induction of p21(waf1/cip1).
Author: Traka, Maria H|Chambers, Karen F|Lund, Elizabeth K|Goodlad, Robert A|Johnson, Ian T|Mithen, Richard F
PMID: 19116884
39.
Journal: Oncogene. 2009 Mar 5;28(9):1197-205.
Title: Mouse embryonic fibroblasts null for the Kruppel-like factor 4 gene are genetically unstable.
Author: Hagos, E G|Ghaleb, A M|Dalton, W B|Bialkowska, A B|Yang, V W
PMID: 19137014
40.
Journal: Gastroenterology. 2009 Jul;137(1):156-64, 164.e1-3.
Title: The symplekin/ZONAB complex inhibits intestinal cell differentiation by the repression of AML1/Runx1.
Author: Buchert, Michael|Darido, Charbel|Lagerqvist, Ebba|Sedello, Anna|Cazevieille, Chantal|Buchholz, Frank|Bourgaux, Jean-Francois|Pannequin, Julie|Joubert, Dominique|Hollande, Frederic
PMID: 19328795
41.
Journal: Mech Dev. 2009 Aug-Sep;126(8-9):650-64.
Title: Kruppel-like factor 4, a "pluripotency transcription factor" highly expressed in male postmeiotic germ cells, is dispensable for spermatogenesis in the mouse.
Author: Godmann, Maren|Gashaw, Isabella|Katz, Jonathan P|Nagy, Andras|Kaestner, Klaus H|Behr, Rudiger
PMID: 19539755
42.
Journal: Int J Cancer. 2009 Dec 15;125(12):2802-9.
Title: KLF4-dependent, PPARgamma-induced expression of GPA33 in colon cancer cell lines.
Author: Rageul, Julie|Mottier, Stephanie|Jarry, Anne|Shah, Yatrik|Theoleyre, Sandrine|Masson, Damien|Gonzalez, Frank J|Laboisse, Christian L|Denis, Marc G
PMID: 19551868
43.
Journal: Ann Surg Oncol. 2009 Sep;16(9):2638-44.
Title: Comprehensive analysis of the clinical significance of inducing pluripotent stemness-related gene expression in colorectal cancer cells.
Author: Saiki, Yasumitsu|Ishimaru, Shinya|Mimori, Koshi|Takatsuno, Yasushi|Nagahara, Makoto|Ishii, Hideshi|Yamada, Kazutaka|Mori, Masaki
PMID: 19554373
44.
Journal: Mol Cancer Ther. 2009 Sep;8(9):2586-96.
Title: A novel small molecule with potent anticancer activity inhibits cell growth by modulating intracellular labile zinc homeostasis.
Author: Huesca, Mario|Lock, Lisa S|Khine, Aye Aye|Viau, Stephane|Peralta, Robert|Cukier, I Howard|Jin, Hongnan|Al-Qawasmeh, Raed A|Lee, Yoon|Wright, Jim|Young, Aiping
PMID: 19755513
45.
Journal: Nat Cell Biol. 2009 Dec;11(12):1487-95.
Title: The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs.
Author: Wellner, Ulrich|Schubert, Jorg|Burk, Ulrike C|Schmalhofer, Otto|Zhu, Feng|Sonntag, Annika|Waldvogel, Bettina|Vannier, Corinne|Darling, Douglas|zur Hausen, Axel|Brunton, Valerie G|Morton, Jennifer|Sansom, Owen|Schuler, Julia|Stemmler, Marc P|Herzberger, Ch
PMID: 19935649
46.
Journal: Cancer Chemother Pharmacol. 2010 May;66(1):141-50.
Title: Peroxisome proliferator-activated receptor gamma-dependent activity of indole ring-substituted 1,1-bis(3'-indolyl)-1-(p-biphenyl)methanes in cancer cells.
Author: Guo, Jingjing|Chintharlapalli, Sudhakar|Lee, Syng-ook|Cho, Sung Dae|Lei, Ping|Papineni, Sabitha|Safe, Stephen
PMID: 19823826
47.
Journal: Mol Cell Biol. 2010 Jan;30(2):372-81.
Title: KLF4 interacts with beta-catenin/TCF4 and blocks p300/CBP recruitment by beta-catenin.
Author: Evans, Paul M|Chen, Xi|Zhang, Wen|Liu, Chunming
PMID: 19901072
48.
Journal: Cancer Res. 2010 Jan 15;70(2):609-20.
Title: Apoptotic sensitivity of colon cancer cells to histone deacetylase inhibitors is mediated by an Sp1/Sp3-activated transcriptional program involving immediate-early gene induction.
Author: Wilson, Andrew J|Chueh, Anderly C|Togel, Lars|Corner, Georgia A|Ahmed, Naseem|Goel, Sanjay|Byun, Do-Sun|Nasser, Shannon|Houston, Michele A|Jhawer, Minaxi|Smartt, Helena J M|Murray, Lucas B|Nicholas, Courtney|Heerdt, Barbara G|Arango, Diego|Augenlicht, Leo
PMID: 20068171
49.
Journal: Eur J Pharmacol. 2010 Jul 10;637(1-3):30-7.
Title: MCC-555-induced NAG-1 expression is mediated in part by KLF4.
Author: Cekanova, Maria|Lee, Seong-Ho|McEntee, Michael F|Baek, Seung Joon
PMID: 20385121
50.
Journal: Cancer Epidemiol Biomarkers Prev. 2010 Oct;19(10):2631-8.
Title: Expression of the tumor suppressor Kruppel-like factor 4 as a prognostic predictor for colon cancer.
Author: Patel, Nilesh V|Ghaleb, Amr M|Nandan, Mandayam O|Yang, Vincent W
PMID: 20699379
51.
Journal: Cancer Prev Res (Phila). 2011 Jan;4(1):116-27.
Title: Resveratrol-induced apoptosis is mediated by early growth response-1, Kruppel-like factor 4, and activating transcription factor 3.
Author: Whitlock, Nichelle C|Bahn, Jae Hoon|Lee, Seong-Ho|Eling, Thomas E|Baek, Seung Joon
PMID: 21205742
52.
Journal: Cancer Res. 2011 Jun 15;71(12):4260-8.
Title: LIN28B promotes colon cancer progression and metastasis.
Author: King, Catrina E|Cuatrecasas, Miriam|Castells, Antoni|Sepulveda, Antonia R|Lee, Ju-Seog|Rustgi, Anil K
PMID: 21512136
53.
Journal: Clin Cancer Res. 2011 Jun 1;17(11):3558-68.
Title: KLF4-mediated negative regulation of IFITM3 expression plays a critical role in colon cancer pathogenesis.
Author: Li, Dawei|Peng, Zhihai|Tang, Huamei|Wei, Ping|Kong, Xiangyu|Yan, Dongwang|Huang, Fei|Li, Qiang|Le, Xiangdong|Li, Qi|Xie, Keping
PMID: 21531817
54.
Journal: Oncol Rep. 2011 Nov;26(5):1181-7.
Title: Acetylbritannilactone suppresses growth via upregulation of kruppel-like transcription factor 4 expression in HT-29 colorectal cancer cells.
Author: Fang, Xin-Mei|Liu, Bin|Liu, Ya-Bin|Wang, Jun-Jie|Wen, Jin-Kun|Li, Bing-Hui|Han, Mei
PMID: 21811764
55.
Journal: Gut Liver. 2011 Jun;5(2):154-9.
Title: KLF4 Expression Correlates with the Degree of Differentiation in Colorectal Cancer.
Author: Hu, Ruolei|Zuo, Yan|Zuo, Li|Liu, Chao|Zhang, Sumei|Wu, Qiang|Zhou, Qing|Gui, Shuyu|Wei, Wei|Wang, Yuan
PMID: 21814594
56.
Journal: J Biol Chem. 2012 Feb 3;287(6):3760-8.
Title: Regulation of the potential marker for intestinal cells, Bmi1, by beta-catenin and the zinc finger protein KLF4: implications for colon cancer.
Author: Yu, Tianxin|Chen, Xi|Zhang, Wen|Colon, Deannon|Shi, Jiandang|Napier, Dana|Rychahou, Piotr|Lu, Wange|Lee, Eun Y|Weiss, Heidi L|Evers, B Mark|Liu, Chunming
PMID: 22170051
57.
Journal: J Zhejiang Univ Sci B. 2012 Jan;13(1):11-9.
Title: Induced pluripotent stem cell-related genes influence biological behavior and 5-fluorouracil sensitivity of colorectal cancer cells.
Author: Shi, Zhong|Bai, Rui|Fu, Zhi-xuan|Zhu, Yong-liang|Wang, Rong-fu|Zheng, Shu
PMID: 22205615
58.
Journal: Mol Cell. 2012 Jan 27;45(2):233-43.
Title: Regulation of KLF4 turnover reveals an unexpected tissue-specific role of pVHL in tumorigenesis.
Author: Gamper, Armin M|Qiao, Xinxian|Kim, Jennifer|Zhang, Liyong|DeSimone, Michelle C|Rathmell, W Kimryn|Wan, Yong
PMID: 22284679
59.
Journal: Int J Oncol. 2012 May;40(5):1423-30.
Title: Hypoxia and TP53 deficiency for induced pluripotent stem cell-like properties in gastrointestinal cancer.
Author: Hoshino, Hiromitsu|Nagano, Hiroaki|Haraguchi, Naotsugu|Nishikawa, Shimpei|Tomokuni, Akira|Kano, Yoshihiro|Fukusumi, Takahito|Saito, Toshiyuki|Ozaki, Miyuki|Sakai, Daisuke|Satoh, Taroh|Eguchi, Hidetoshi|Sekimoto, Mitsugu|Doki, Yuichiro|Mori, Masaki|Ishii,
PMID: 22293932
60.
Journal: PLoS One. 2012;7(2):e32492.
Title: Kruppel-like factor 4 regulates intestinal epithelial cell morphology and polarity.
Author: Yu, Tianxin|Chen, Xi|Zhang, Wen|Li, Juan|Xu, Ren|Wang, Timothy C|Ai, Walden|Liu, Chunming
PMID: 22384261
61.
Journal: J Biol Chem. 2012 Apr 20;287(17):13584-97.
Title: Novel insight into KLF4 proteolytic regulation in estrogen receptor signaling and breast carcinogenesis.
Author: Hu, Dong|Zhou, Zhuan|Davidson, Nancy E|Huang, Yi|Wan, Yong
PMID: 22389506
62.
Journal: Int J Mol Med. 2012 Jun;29(6):1060-4.
Title: Dicer 1, ribonuclease type III modulates a reprogramming effect in colorectal cancer cells.
Author: Dewi, Dyah Laksmi|Ishii, Hideshi|Haraguchi, Naotsugu|Nishikawa, Shimpei|Kano, Yoshihiro|Fukusumi, Takahito|Ozaki, Miyuki|Saito, Toshiyuki|Sakai, Daisuke|Satoh, Taroh|Doki, Yuichiro|Mori, Masaki
PMID: 22446887
63.
Journal: Cancer Res. 2012 Jul 15;72(14):3631-41.
Title: miR-103/107 promote metastasis of colorectal cancer by targeting the metastasis suppressors DAPK and KLF4.
Author: Chen, Hsin-Yi|Lin, Yu-Min|Chung, Hsiang-Ching|Lang, Yaw-Dong|Lin, Ching-Jung|Huang, John|Wang, Wei-Chi|Lin, Feng-Mao|Chen, Zhen|Huang, Hsien-Da|Shyy, John Y-J|Liang, Jin-Tung|Chen, Ruey-Hwa
PMID: 22593189
64.
Journal: BMC Syst Biol. 2012 Jun 15;6:68.
Title: Identifying microRNA-mRNA regulatory network in colorectal cancer by a combination of expression profile and bioinformatics analysis.
Author: Fu, Jihong|Tang, Wentao|Du, Peng|Wang, Guanghui|Chen, Wei|Li, Jingming|Zhu, Yunxiang|Gao, Jun|Cui, Long
PMID: 22703586
65.
Journal: Clin Epigenetics. 2012 Sep 24;4(1):16.
Title: A role for low-abundance miRNAs in colon cancer: the miR-206/Kruppel-like factor 4 (KLF4) axis.
Author: Parasramka, Mansi A|Dashwood, W Mohaiza|Wang, Rong|Saeed, Hassaan H|Williams, David E|Ho, Emily|Dashwood, Roderick H
PMID: 23006636
66.
Journal: Acta Biochim Pol. 2012;59(4):467-74. Epub 2012 Nov 21.
Title: The role of microRNA in metastatic colorectal cancer and its significance in cancer prognosis and treatment.
Author: Tokarz, Paulina|Blasiak, Janusz
PMID: 23173124
67.
Journal: Mol Hum Reprod. 2013 Feb;19(2):57-71.
Title: Oncogenic Wnt/beta-catenin signalling pathways in the cancer-resistant epididymis have implications for cancer research.
Author: Wang, K|Li, N|Yeung, C H|Li, J Y|Wang, H Y|Cooper, T G
PMID: 23155044
68.
Journal: J Clin Invest. 2013 Jan;123(1):299-314.
Title: CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPARgamma signaling.
Author: Faber, Katrin|Bullinger, Lars|Ragu, Christine|Garding, Angela|Mertens, Daniel|Miller, Christina|Martin, Daniela|Walcher, Daniel|Dohner, Konstanze|Dohner, Hartmut|Claus, Rainer|Plass, Christoph|Sykes, Stephen M|Lane, Steven W|Scholl, Claudia|Frohling, Stef
PMID: 23202735
69.
Journal: PLoS One. 2013;8(2):e55620.
Title: Bacteria regulate intestinal epithelial cell differentiation factors both in vitro and in vivo.
Author: Becker, Svetlana|Oelschlaeger, Tobias A|Wullaert, Andy|Vlantis, Katerina|Pasparakis, Manolis|Wehkamp, Jan|Stange, Eduard F|Gersemann, Michael
PMID: 23418447
70.
Journal: PLoS One. 2013;8(2):e56082.
Title: Kruppel-like factor 4 acts as an oncogene in colon cancer stem cell-enriched spheroid cells.
Author: Leng, Zhengwei|Tao, Kaixiong|Xia, Qinghua|Tan, Jun|Yue, Zhongyi|Chen, Jinhuang|Xi, Hailin|Li, Jie|Zheng, Hai
PMID: 23418515
71.
Journal: Cell Commun Signal. 2013 Mar 4;11(1):17.
Title: Excellence in cell signaling research recognized with major new award.
Author: Feller, Stephan M
PMID: 23497077
72.
Journal: Oncotarget. 2013 Feb;4(2):174-5.
Title: Deregulation of the CDX2-KLF4 axis in acute myeloid leukemia and colon cancer.
Author: Rouhi, Arefeh|Frohling, Stefan
PMID: 23563447
73.
Journal: Carcinogenesis. 2013 Oct;34(10):2415-23.
Title: Suppression of colon carcinogenesis by targeting Notch signaling.
Author: Miyamoto, Shingo|Nakanishi, Masako|Rosenberg, Daniel W
PMID: 23729655
74.
Journal: Toxicol Lett. 2013 Oct 24;222(2):139-45.
Title: Salinomycin induces apoptosis in cisplatin-resistant colorectal cancer cells by accumulation of reactive oxygen species.
Author: Zhou, Jin|Li, Pu|Xue, Xiaofeng|He, Songbing|Kuang, Yuting|Zhao, Hong|Chen, Shaoji|Zhi, Qiaoming|Guo, Xiaobo
PMID: 23916687
75.
Journal: Mol Cancer. 2013 Aug 6;12:89.
Title: Kruppel-like factor 4 regulates genetic stability in mouse embryonic fibroblasts.
Author: El-Karim, Enas A|Hagos, Engda G|Ghaleb, Amr M|Yu, Bing|Yang, Vincent W
PMID: 23919723
76.
Journal: PLoS One. 2013 Sep 4;8(9):e72435.
Title: Epigenetic regulation of pluripotent genes mediates stem cell features in human hepatocellular carcinoma and cancer cell lines.
Author: Wang, Xiao Qi|Ng, Ray Kit|Ming, Xiaoyan|Zhang, Wu|Chen, Lin|Chu, Andrew C Y|Pang, Roberta|Lo, Chung Mau|Tsao, Sai Wah|Liu, Xuqing|Poon, Ronnie T P|Fan, Sheung Tat
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Journal: PLoS Genet. 2013 Oct;9(10):e1003913.
Title: Loss of miR-10a activates lpo and collaborates with activated Wnt signaling in inducing intestinal neoplasia in female mice.
Author: Stadthagen, Gustavo|Tehler, Disa|Hoyland-Kroghsbo, Nina Molin|Wen, Jiayu|Krogh, Anders|Jensen, Klaus T|Santoni-Rugiu, Eric|Engelholm, Lars H|Lund, Anders H
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Journal: Br J Cancer. 2014 Jan 21;110(2):450-8.
Title: MicroRNA-29a promotes colorectal cancer metastasis by regulating matrix metalloproteinase 2 and E-cadherin via KLF4.
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Journal: Oncotarget. 2014 Jun 30;5(12):4492-503.
Title: Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLI-DNA binding.
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Journal: PLoS One. 2014 Jul 9;9(7):e101735.
Title: Induction of cancer stem cell properties in colon cancer cells by defined factors.
Author: Oshima, Nobu|Yamada, Yasuhiro|Nagayama, Satoshi|Kawada, Kenji|Hasegawa, Suguru|Okabe, Hiroshi|Sakai, Yoshiharu|Aoi, Takashi
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Journal: World J Surg Oncol. 2014 Jul 24;12:232.
Title: High KLF4 level in normal tissue predicts poor survival in colorectal cancer patients.
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Journal: Ann Surg Oncol. 2015 Dec;22 Suppl 3:S1394-401.
Title: A Cancer Reprogramming Method Using MicroRNAs as a Novel Therapeutic Approach against Colon Cancer: Research for Reprogramming of Cancer Cells by MicroRNAs.
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Journal: Int J Oncol. 2015 Apr;46(4):1551-9.
Title: The effectiveness of an anti-human IL-6 receptor monoclonal antibody combined with chemotherapy to target colon cancer stem-like cells.
Author: Ying, Jin|Tsujii, Masahiko|Kondo, Jumpei|Hayashi, Yoshito|Kato, Motohiko|Akasaka, Tomofumi|Inoue, Takuta|Shiraishi, Eri|Inoue, Tahahiro|Hiyama, Satoshi|Tsujii, Yoshiki|Maekawa, Akira|Kawai, Shoichiro|Fujinaga, Tetsuji|Araki, Maekawa|Shinzaki, Shinichiro|W
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Journal: PLoS One. 2015 May 13;10(5):e0127119.
Title: MicroRNAs Induce Epigenetic Reprogramming and Suppress Malignant Phenotypes of Human Colon Cancer Cells.
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Journal: Sci Rep. 2015 May 28;5:10357.
Title: Identification of a distinct population of CD133(+)CXCR4(+) cancer stem cells in ovarian cancer.
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Journal: Invest New Drugs. 2015 Oct;33(5):1086-92.
Title: Phase 1 study of APTO-253 HCl, an inducer of KLF4, in patients with advanced or metastatic solid tumors.
Author: Cercek, Andrea|Wheler, Jennifer|Murray, Peter E|Zhou, Shawn|Saltz, Leonard
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Journal: Iran J Cancer Prev. 2015 Oct;8(5):e3446.
Title: Verification of ALDH Activity as a Biomarker in Colon Cancer Stem Cells-Derived HT-29 Cell Line.
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Journal: J Mol Cell Biol. 2016 Apr;8(2):157-73.
Title: In vivo epigenetic reprogramming of primary human colon cancer cells enhances metastases.
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Journal: Tumour Biol. 2016 Jan;37(1):463-71.
Title: MiR-375 targets KLF4 and impacts the proliferation of colorectal carcinoma.
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Journal: Mol Cancer Res. 2016 Apr;14(4):385-96.
Title: KLF4 Suppresses Tumor Formation in Genetic and Pharmacological Mouse Models of Colonic Tumorigenesis.
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Journal: Genes Chromosomes Cancer. 2016 Apr;55(4):311-321.
Title: Integrated genomic profiling identifies microRNA-92a regulation of IQGAP2 in locally advanced rectal cancer.
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Title: Labeling of target mRNAs using a photo-reactive microRNA probe.
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Journal: Oncol Res. 2016;23(6):283-90.
Title: MicroRNA-92a Promotes Colorectal Cancer Cell Growth and Migration by Inhibiting KLF4.
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Journal: PLoS One. 2016 Jun 6;11(6):e0156871.
Title: MiR-205 and MiR-373 Are Associated with Aggressive Human Mucinous Colorectal Cancer.
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Journal: Oncotarget. 2016 Nov 29;7(48):78726-78735.
Title: MFHAS1 promotes colorectal cancer progress by regulating polarization of tumor-associated macrophages via STAT6 signaling pathway.
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Journal: Oncol Res. 2016 May;23(6):283-290.
Title: MicroRNA-92a Promotes Colorectal Cancer Cell Growth and Migration by Inhibiting KLF4.
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Journal: BMC Cancer. 2017 Jan 13;17(1):50.
Title: Delta-like 4/Notch signaling promotes Apc (Min/+) tumor initiation through angiogenic and non-angiogenic related mechanisms.
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Journal: Genet Mol Res. 2017 Feb 16;16(1). pii: gmr-16-01-gmr.16019272.
Title: Tumor-suppressive role of Kruppel-like factor 4 (KLF-4) in colorectal cancer.
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Journal: Arch Toxicol. 2017 Oct;91(10):3415-3425.
Title: A miRNA signature for an environmental heterocyclic amine defined by a multi-organ carcinogenicity bioassay in the rat.
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Journal: World J Stem Cells. 2017 May 26;9(5):77-88.
Title: Next-generation sequencing traces human induced pluripotent stem cell lines clonally generated from heterogeneous cancer tissue.
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Journal: Oncol Rep. 2017 Aug;38(2):975-984.
Title: KLF4 inhibits colorectal cancer cell proliferation dependent on NDRG2 signaling.
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Journal: Genes Chromosomes Cancer. 2017 Nov;56(11):769-787.
Title: The co-regulatory networks of tumor suppressor genes, oncogenes, and miRNAs in colorectal cancer.
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Journal: Mol Cancer Res. 2017 Oct;15(10):1455-1466.
Title: The Tissue-Reconstructing Ability of Colon CSCs Is Enhanced by FK506 and Suppressed by GSK3 Inhibition.
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Journal: Cancer Gene Ther. 2017 Sep;24(9):361-366.
Title: Kruppel-like factor 4 acts as a potential therapeutic target of Sijunzi decoction for treatment of colorectal cancer.
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Journal: World J Gastroenterol. 2017 Jul 28;23(28):5127-5145.
Title: Involvement of CRF2 signaling in enterocyte differentiation.
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Journal: Oncotarget. 2017 Jul 22;8(35):59246-59256.
Title: miR-543 promotes colorectal cancer proliferation and metastasis by targeting KLF4.
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Journal: Med Sci Monit. 2017 Dec 3;23:5735-5743.
Title: Identification of Key Genes in Colorectal Cancer Regulated by miR-34a.
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Journal: Oncotarget. 2017 Oct 9;8(60):101760-101770.
Title: MiR-92a promotes stem cell-like properties by activating Wnt/beta-catenin signaling in colorectal cancer.
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Journal: Oncotarget. 2017 Nov 1;8(60):102176-102190.
Title: Commensal-infected macrophages induce dedifferentiation and reprogramming of epithelial cells during colorectal carcinogenesis.
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Journal: Front Surg. 2018 Jan 22;4:76.
Title: Characterization of Cancer Stem Cells in Colon Adenocarcinoma Metastasis to the Liver.
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Journal: Cell Biol Int. 2018 Apr;42(4):495-503.
Title: Activation of KLF4 expression by small activating RNA promotes migration and invasion in colorectal epithelial cells.
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Journal: Cell Commun Adhes. 2018 Dec;24(1):1-10.
Title: Kruppel-like factor 4 mediates cellular migration and invasion by altering RhoA activity.
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Journal: Gastroenterol Hepatol Bed Bench. 2018 Winter;11(1):34-41.
Title: Extracted metabolite from Streptomyces Levis ABRIINW111 altered the gene expression in colon cancer.
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Journal: Cell Physiol Biochem. 2018;46(2):860-872.
Title: Lgr5+CD44+EpCAM+ Strictly Defines Cancer Stem Cells in Human Colorectal Cancer.
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Journal: Cancer Prev Res (Phila). 2018 Aug;11(8):503-510.
Title: KLF4 Mediates the Effect of 5-ASA on the beta-Catenin Pathway in Colon Cancer Cells.
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Journal: J Nutr. 2018 Apr 20. pii: 4979589.
Title: Dietary Red Raspberry Reduces Colorectal Inflammation and Carcinogenic Risk in Mice with Dextran Sulfate Sodium-Induced Colitis.
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Journal: Mol Cancer Res. 2018 Aug 14. pii: 1541-7786.MCR-18-0399.
Title: Increased genetic instability and accelerated progression of colitis-associated colorectal cancer through intestinal epithelium-specific deletion of Klf4.
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Journal: Biomed Pharmacother. 2018 Oct;106:1370-1377.
Title: MiR-92a promotes tumorigenesis of colorectal cancer, a transcriptomic and functional based study.
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Journal: Cell Tissue Res. 2018 Oct 3. pii: 10.1007/s00441-018-2933-8.
Title: Cell biological profiling of reprogrammed cancer stem cell-like colon cancer cells maintained in culture.
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Journal: Br J Cancer. 2018 Oct;119(7):855-863.
Title: Analysis of cell proliferation and tissue remodelling uncovers a KLF4 activity score associated with poor prognosis in colorectal cancer.
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