Primary Site >> Colorectal Cancer

Gene >> KDM4A

Journal: J Cell Biochem. 2012 Apr;113(4):1368-76.
Title: The JMJD2A demethylase regulates apoptosis and proliferation in colon cancer cells.
Author: Kim, Tae-Dong|Shin, Sook|Berry, William L|Oh, Sangphil|Janknecht, Ralf
PMID: 22134899
Journal: J Med Chem. 2014 Jan 9;57(1):42-55.
Title: Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities.
Author: Rotili, Dante|Tomassi, Stefano|Conte, Mariarosaria|Benedetti, Rosaria|Tortorici, Marcello|Ciossani, Giuseppe|Valente, Sergio|Marrocco, Biagina|Labella, Donatella|Novellino, Ettore|Mattevi, Andrea|Altucci, Lucia|Tumber, Anthony|Yapp, Clarence|King, Oliver
PMID: 24325601
Journal: Am J Transl Res. 2014 May 15;6(3):236-47. eCollection 2014.
Title: Pro-growth role of the JMJD2C histone demethylase in HCT-116 colon cancer cells and identification of curcuminoids as JMJD2 inhibitors.
Author: Kim, Tae-Dong|Fuchs, James R|Schwartz, Eric|Abdelhamid, Dalia|Etter, Jonathan|Berry, William L|Li, Chenglong|Ihnat, Michael A|Li, Pui-Kai|Janknecht, Ralf
PMID: 24936217
Journal: Oncogene. 2016 Feb 11;35(6):793-9.
Title: H3K9me3 facilitates hypoxia-induced p53-dependent apoptosis through repression of APAK.
Author: Olcina, M M|Leszczynska, K B|Senra, J M|Isa, N F|Harada, H|Hammond, E M
PMID: 25961932
Journal: Oncotarget. 2016 Feb 2;7(5):6074-87.
Title: Lanatoside C suppressed colorectal cancer cell growth by inducing mitochondrial dysfunction and increased radiation sensitivity by impairing DNA damage repair.
Author: Kang, Mi Ae|Kim, Mi-Sook|Kim, Wonwoo|Um, Jee-Hyun|Shin, Young-Joo|Song, Jie-Young|Jeong, Jae-Hoon
PMID: 26756216
Journal: Invest New Drugs. 2017 Dec;35(6):733-741.
Title: Novel inhibitors of lysine (K)-specific Demethylase 4A with anticancer activity.
Author: Lee, Hyo Jeong|Kim, Bo-Kyoung|Yoon, Kyoung Bin|Kim, Yong-Chul|Han, Sun-Young
PMID: 28905188
Journal: Oncogene. 2018 Oct 18. pii: 10.1038/s41388-018-0519-2.
Title: CXCR7/CXCR4 heterodimer-induced histone demethylation: a new mechanism of colorectal tumorigenesis.
Author: Song, Zhi-Yu|Wang, Feng|Cui, Shu-Xiang|Gao, Zu-Hua|Qu, Xian-Jun
PMID: 30337690