Primary Site >> Colorectal Cancer
Gene >> KDM4A
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Ref: The JMJD2A demethylase regulates apoptosis and proliferation in colon cancer cells. PMID: 22134899 |
Ref: Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities. PMID: 24325601 Ref: Pro-growth role of the JMJD2C histone demethylase in HCT-116 colon cancer cells and identification of curcuminoids as JMJD2 inhibitors. PMID: 24936217 |
Ref: H3K9me3 facilitates hypoxia-induced p53-dependent apoptosis through repression of APAK. PMID: 25961932 Ref: Lanatoside C suppressed colorectal cancer cell growth by inducing mitochondrial dysfunction and increased radiation sensitivity by impairing DNA damage repair. PMID: 26756216 |
Ref: Novel inhibitors of lysine (K)-specific Demethylase 4A with anticancer activity. PMID: 28905188 |
Ref: CXCR7/CXCR4 heterodimer-induced histone demethylation: a new mechanism of colorectal tumorigenesis. PMID: 30337690 |