Primary Site >> Colorectal Cancer
Gene >> KDM1A
| 1. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2007 May 8;104(19):8023-8. | ||||||||||
| Title: | Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes. | ||||||||||
| Author: | Huang, Yi|Greene, Eriko|Murray Stewart, Tracy|Goodwin, Andrew C|Baylin, Stephen B|Woster, Patrick M|Casero, Robert A Jr | ||||||||||
| PMID: | 17463086 | ||||||||||
| 2. | |||||||||||
| Journal: | Clin Cancer Res. 2009 Dec 1;15(23):7217-28. | ||||||||||
| Title: | Novel oligoamine analogues inhibit lysine-specific demethylase 1 and induce reexpression of epigenetically silenced genes. | ||||||||||
| Author: | Huang, Yi|Stewart, Tracy Murray|Wu, Yu|Baylin, Stephen B|Marton, Laurence J|Perkins, Brandy|Jones, Richard J|Woster, Patrick M|Casero, Robert A Jr | ||||||||||
| PMID: | 19934284 | ||||||||||
| 3. | |||||||||||
| Journal: | Int J Cancer. 2011 Feb 1;128(3):574-86. | ||||||||||
| Title: | Overexpression of LSD1 contributes to human carcinogenesis through chromatin regulation in various cancers. | ||||||||||
| Author: | Hayami, Shinya|Kelly, John D|Cho, Hyun-Soo|Yoshimatsu, Masanori|Unoki, Motoko|Tsunoda, Tatsuhiko|Field, Helen I|Neal, David E|Yamaue, Hiroki|Ponder, Bruce A J|Nakamura, Yusuke|Hamamoto, Ryuji | ||||||||||
| PMID: | 20333681 | ||||||||||
| 4. | |||||||||||
| Journal: | Biochem J. 2012 Mar 15;442(3):693-701. | ||||||||||
| Title: | Oligoamine analogues in combination with 2-difluoromethylornithine synergistically induce re-expression of aberrantly silenced tumour-suppressor genes. | ||||||||||
| Author: | Wu, Yu|Steinbergs, Nora|Murray-Stewart, Tracy|Marton, Laurence J|Casero, Robert A | ||||||||||
| PMID: | 22132744 | ||||||||||
| 5. | |||||||||||
| Journal: | Nucleic Acids Res. 2012 May;40(10):4334-46. | ||||||||||
| Title: | DNMT1 modulates gene expression without its catalytic activity partially through its interactions with histone-modifying enzymes. | ||||||||||
| Author: | Clements, Eriko G|Mohammad, Helai P|Leadem, Benjamin R|Easwaran, Hariharan|Cai, Yi|Van Neste, Leander|Baylin, Stephen B | ||||||||||
| PMID: | 22278882 | ||||||||||
| 6. | |||||||||||
| Journal: | Br J Cancer. 2013 Aug 20;109(4):994-1003. | ||||||||||
| Title: | LSD1-mediated epigenetic modification contributes to proliferation and metastasis of colon cancer. | ||||||||||
| Author: | Ding, J|Zhang, Z-M|Xia, Y|Liao, G-Q|Pan, Y|Liu, S|Zhang, Y|Yan, Z-S | ||||||||||
| PMID: | 23900215 | ||||||||||
| 7. | |||||||||||
| Journal: | Genes Dev. 2013 Nov 15;27(22):2473-88. | ||||||||||
| Title: | alpha-Catenin interacts with APC to regulate beta-catenin proteolysis and transcriptional repression of Wnt target genes. | ||||||||||
| Author: | Choi, Seung H|Estaras, Conchi|Moresco, James J|Yates, John R 3rd|Jones, Katherine A | ||||||||||
| PMID: | 24240237 | ||||||||||
| 8. | |||||||||||
| Journal: | J Med Chem. 2013 Dec 12;56(23):9496-508. | ||||||||||
| Title: | High-throughput virtual screening identifies novel N'-(1-phenylethylidene)-benzohydrazides as potent, specific, and reversible LSD1 inhibitors. | ||||||||||
| Author: | Sorna, Venkataswamy|Theisen, Emily R|Stephens, Bret|Warner, Steven L|Bearss, David J|Vankayalapati, Hariprasad|Sharma, Sunil | ||||||||||
| PMID: | 24237195 | ||||||||||
| 9. | |||||||||||
| Journal: | PLoS One. 2013 Jul 26;8(7):e70077. | ||||||||||
| Title: | Lysine-specific demethylase 1 (LSD1/KDM1A) contributes to colorectal tumorigenesis via activation of the Wnt/beta-catenin pathway by down-regulating Dickkopf-1 (DKK1) [corrected]. | ||||||||||
| Author: | Huang, Zebin|Li, Shangze|Song, Wei|Li, Xin|Li, Qinshan|Zhang, Zeyan|Han, Yongqing|Zhang, Xiaodong|Miao, Shiying|Du, Runlei|Wang, Linfang | ||||||||||
| PMID: | 23922913 | ||||||||||
| 10. | |||||||||||
| Journal: | Br J Cancer. 2013 Jul 23;109(2):299-306. | ||||||||||
| Title: | Functional and cancer genomics of ASXL family members. | ||||||||||
| Author: | Katoh, M | ||||||||||
| PMID: | 23736028 | ||||||||||
| 11. | |||||||||||
| Journal: | Int J Cancer. 2013 Sep 1;133(5):1064-73. | ||||||||||
| Title: | MiR-137 functions as a tumor suppressor in neuroblastoma by downregulating KDM1A. | ||||||||||
| Author: | Althoff, Kristina|Beckers, Anneleen|Odersky, Andrea|Mestdagh, Pieter|Koster, Johannes|Bray, Isabella M|Bryan, Kenneth|Vandesompele, Jo|Speleman, Frank|Stallings, Raymond L|Schramm, Alexander|Eggert, Angelika|Sprussel, Annika|Schulte, Johannes H | ||||||||||
| PMID: | 23400681 | ||||||||||
| 12. | |||||||||||
| Journal: | Dig Dis Sci. 2013 Jun;58(6):1581-9. | ||||||||||
| Title: | Positive expression of LSD1 and negative expression of E-cadherin correlate with metastasis and poor prognosis of colon cancer. | ||||||||||
| Author: | Jie, Ding|Zhongmin, Zhang|Guoqing, Liao|Sheng, Liu|Yi, Zhang|Jing, Wen|Liang, Zeng | ||||||||||
| PMID: | 23314859 | ||||||||||
| 13. | |||||||||||
| Journal: | Biochem J. 2013 Jan 15;449(2):459-68. | ||||||||||
| Title: | Loss of LSD1 (lysine-specific demethylase 1) suppresses growth and alters gene expression of human colon cancer cells in a p53- and DNMT1(DNA methyltransferase 1)-independent manner. | ||||||||||
| Author: | Jin, Lihua|Hanigan, Christin L|Wu, Yu|Wang, Wei|Park, Ben Ho|Woster, Patrick M|Casero, Robert A | ||||||||||
| PMID: | 23072722 | ||||||||||
| 14. | |||||||||||
| Journal: | J Med Chem. 2014 Jan 9;57(1):42-55. | ||||||||||
| Title: | Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities. | ||||||||||
| Author: | Rotili, Dante|Tomassi, Stefano|Conte, Mariarosaria|Benedetti, Rosaria|Tortorici, Marcello|Ciossani, Giuseppe|Valente, Sergio|Marrocco, Biagina|Labella, Donatella|Novellino, Ettore|Mattevi, Andrea|Altucci, Lucia|Tumber, Anthony|Yapp, Clarence|King, Oliver | ||||||||||
| PMID: | 24325601 | ||||||||||
| 15. | |||||||||||
| Journal: | Int J Cancer. 2014 Nov 1;135(9):2014-23. | ||||||||||
| Title: | Calcium-sensing receptor silencing in colorectal cancer is associated with promoter hypermethylation and loss of acetylation on histone 3. | ||||||||||
| Author: | Fetahu, Irfete S|Hobaus, Julia|Aggarwal, Abhishek|Hummel, Doris M|Tennakoon, Samawansha|Mesteri, Ildiko|Baumgartner-Parzer, Sabina|Kallay, Eniko | ||||||||||
| PMID: | 24691920 | ||||||||||
| 16. | |||||||||||
| Journal: | Cell Rep. 2014 Jul 24;8(2):501-13. | ||||||||||
| Title: | Silencing of the DNA mismatch repair gene MLH1 induced by hypoxic stress in a pathway dependent on the histone demethylase LSD1. | ||||||||||
| Author: | Lu, Yuhong|Wajapeyee, Narendra|Turker, Mitchell S|Glazer, Peter M | ||||||||||
| PMID: | 25043185 | ||||||||||
| 17. | |||||||||||
| Journal: | J Cancer Res Clin Oncol. 2015 Jan;141(1):11-21. | ||||||||||
| Title: | CBB1003, a lysine-specific demethylase 1 inhibitor, suppresses colorectal cancer cells growth through down-regulation of leucine-rich repeat-containing G-protein-coupled receptor 5 expression. | ||||||||||
| Author: | Hsu, Hung-Chih|Liu, Yi-Shiuan|Tseng, Kai-Chi|Yang, Tsai-Sheng|Yeh, Chien-Yuh|You, Jeng-Fu|Hung, Hsin-Yuan|Chen, Shu-Jen|Chen, Hua-Chien | ||||||||||
| PMID: | 25060070 | ||||||||||
| 18. | |||||||||||
| Journal: | Mol Cancer Res. 2015 Jun;13(6):969-81. | ||||||||||
| Title: | A Protein Interaction between beta-Catenin and Dnmt1 Regulates Wnt Signaling and DNA Methylation in Colorectal Cancer Cells. | ||||||||||
| Author: | Song, Jing|Du, Zhanwen|Ravasz, Mate|Dong, Bohan|Wang, Zhenghe|Ewing, Rob M | ||||||||||
| PMID: | 25753001 | ||||||||||
| 19. | |||||||||||
| Journal: | Mol Oncol. 2015 Feb;9(2):335-54. | ||||||||||
| Title: | SNAIL1 combines competitive displacement of ASCL2 and epigenetic mechanisms to rapidly silence the EPHB3 tumor suppressor in colorectal cancer. | ||||||||||
| Author: | Ronsch, Kerstin|Jagle, Sabine|Rose, Katja|Seidl, Maximilian|Baumgartner, Francis|Freihen, Vivien|Yousaf, Afsheen|Metzger, Eric|Lassmann, Silke|Schule, Roland|Zeiser, Robert|Michoel, Tom|Hecht, Andreas | ||||||||||
| PMID: | 25277775 | ||||||||||
| 20. | |||||||||||
| Journal: | Oncotarget. 2017 Jun 13;8(24):38227-38238. | ||||||||||
| Title: | Long noncoding RNA ZFAS1 promotes gastric cancer cells proliferation by epigenetically repressing KLF2 and NKD2 expression. | ||||||||||
| Author: | Nie, Fengqi|Yu, Xiang|Huang, Mingde|Wang, Yunfei|Xie, Min|Ma, Hongwei|Wang, Zhaoxia|De, Wei|Sun, Ming | ||||||||||
| PMID: | 27246976 | ||||||||||
| 21. | |||||||||||
| Journal: | Oncogenesis. 2017 Jan 23;6(1):e288. | ||||||||||
| Title: | Long noncoding RNA HOXA-AS2 represses P21 and KLF2 expression transcription by binding with EZH2, LSD1 in colorectal cancer. | ||||||||||
| Author: | Ding, J|Xie, M|Lian, Y|Zhu, Y|Peng, P|Wang, J|Wang, L|Wang, K | ||||||||||
| PMID: | 28112720 | ||||||||||
| 22. | |||||||||||
| Journal: | Oncotarget. 2017 Mar 21;8(12):19609-19630. | ||||||||||
| Title: | Identification of downstream metastasis-associated target genes regulated by LSD1 in colon cancer cells. | ||||||||||
| Author: | Chen, Jiang|Ding, Jie|Wang, Ziwei|Zhu, Jian|Wang, Xuejian|Du, Jiyi | ||||||||||
| PMID: | 28121627 | ||||||||||
| 23. | |||||||||||
| Journal: | Zhonghua Yi Xue Za Zhi. 2017 Mar 14;97(10):743-748. | ||||||||||
| Title: | [The influence and mechanisms of lysine-specific demethylase 1 (LSD1) on invasion and metastasis of colon cancer cells]. | ||||||||||
| Author: | Ding, J|Zhang, Z M|Dong, Q|Mi, R|Xu, K S|Yang, X F|Liao, G Q | ||||||||||
| PMID: | 28316154 | ||||||||||
| 24. | |||||||||||
| Journal: | J Biol Chem. 2017 Sep 15;292(37):15205-15215. | ||||||||||
| Title: | Epigenetic suppression of human telomerase (hTERT) is mediated by the metastasis suppressor NME2 in a G-quadruplex-dependent fashion. | ||||||||||
| Author: | Saha, Dhurjhoti|Singh, Ankita|Hussain, Tabish|Srivastava, Vivek|Sengupta, Suman|Kar, Anirban|Dhapola, Parashar|Dhople, Vishnu|Ummanni, Ramesh|Chowdhury, Shantanu | ||||||||||
| PMID: | 28717007 | ||||||||||
| 25. | |||||||||||
| Journal: | Sci Rep. 2017 Aug 4;7(1):7312. | ||||||||||
| Title: | The pseudogene derived from long non-coding RNA DUXAP10 promotes colorectal cancer cell growth through epigenetically silencing of p21 and PTEN. | ||||||||||
| Author: | Lian, Yifan|Xu, Yetao|Xiao, Chuanxing|Xia, Rui|Gong, Huangbo|Yang, Peng|Chen, Tao|Wu, Dongdong|Cai, Zeling|Zhang, Jianping|Wang, Keming | ||||||||||
| PMID: | 28779166 | ||||||||||
| 26. | |||||||||||
| Journal: | J Cell Biochem. 2018 Apr;119(4):3671-3682. | ||||||||||
| Title: | Knockdown of pseudogene derived from lncRNA DUXAP10 inhibits cell proliferation, migration, invasion, and promotes apoptosis in pancreatic cancer. | ||||||||||
| Author: | Lian, Yifan|Xiao, Chuanxing|Yan, Changsheng|Chen, Dajun|Huang, Qingwen|Fan, Yanyun|Li, Zhaohua|Xu, Hongzhi | ||||||||||
| PMID: | 29286182 | ||||||||||
| 27. | |||||||||||
| Journal: | J Cell Biochem. 2018 Jun;119(6):4957-4966. | ||||||||||
| Title: | Lysine-specific demethylase 1 activation by vitamin B2 attenuates efficacy of apatinib for proliferation and migration of gastric cancer cell MGC-803. | ||||||||||
| Author: | Ma, Jin-Lian|Zhang, Ting|Suo, Feng-Zhi|Chang, Jiao|Wan, Xiang-Bin|Feng, Xue-Jian|Zheng, Yi-Chao|Liu, Hong-Min | ||||||||||
| PMID: | 29384217 | ||||||||||
| 28. | |||||||||||
| Journal: | Elife. 2018 Jan 31;7. pii: 29511. | ||||||||||
| Title: | Targeting posttranslational modifications of RIOK1 inhibits the progression of colorectal and gastric cancers. | ||||||||||
| Author: | Hong, Xuehui|Huang, He|Qiu, Xingfeng|Ding, Zhijie|Feng, Xing|Zhu, Yuekun|Zhuo, Huiqin|Hou, Jingjing|Zhao, Jiabao|Cai, Wangyu|Sha, Ruihua|Hong, Xinya|Li, Yongxiang|Song, Hongjiang|Zhang, Zhiyong | ||||||||||
| PMID: | 29384474 | ||||||||||
| 29. | |||||||||||
| Journal: | Bioorg Med Chem. 2018 May 1;26(8):1523-1537. | ||||||||||
| Title: | New histone demethylase LSD1 inhibitor selectively targets teratocarcinoma and embryonic carcinoma cells. | ||||||||||
| Author: | Hoang, Nam|Zhang, Xuan|Zhang, Chunxiao|Vo, Van|Leng, Feng|Saxena, Lovely|Yin, Feng|Lu, Fei|Zheng, Guangrong|Bhowmik, Pradip|Zhang, Hui | ||||||||||
| PMID: | 29439916 | ||||||||||
| 30. | |||||||||||
| Journal: | Bioorg Chem. 2018 Aug;78:7-16. | ||||||||||
| Title: | Design, synthesis and biological activity of 4-(4-benzyloxy)phenoxypiperidines as selective and reversible LSD1 inhibitors. | ||||||||||
| Author: | Xi, Jiayue|Xu, Siyuan|Zhang, Lulu|Bi, Xueyuan|Ren, Yanshen|Liu, Yu-Chih|Gu, Yueqing|Xu, Yungen|Lan, Fei|Zha, Xiaoming | ||||||||||
| PMID: | 29524666 | ||||||||||
| 31. | |||||||||||
| Journal: | J Cancer Res Clin Oncol. 2018 Aug 13. pii: 10.1007/s00432-018-2733-2. | ||||||||||
| Title: | Prognostic value of histone marks H3K27me3 and H3K9me3 and modifying enzymes EZH2, SETDB1 and LSD-1 in colorectal cancer. | ||||||||||
| Author: | Carvalho, Sonia|Freitas, Micaela|Antunes, Luis|Monteiro-Reis, Sara|Vieira-Coimbra, Marcia|Tavares, Ana|Paulino, Sofia|Videira, Jose Flavio|Jeronimo, Carmen|Henrique, Rui | ||||||||||
| PMID: | 30105513 | ||||||||||
| 32. | |||||||||||
| Journal: | Chem Pharm Bull (Tokyo). 2018 Oct 24. | ||||||||||
| Title: | Design, synthesis, and biological evaluation of a conjugate of 5-fluorouracil and an LSD1 inhibitor. | ||||||||||
| Author: | Ota, Yosuke|Nakamura, Arisa|Elboray, Elghareeb E|Itoh, Yukihiro|Suzuki, Takayoshi | ||||||||||
| PMID: | 30369513 | ||||||||||