Primary Site >> Colorectal Cancer
Gene >> KCNH2
| 1. | |||||||||||
| Journal: | Cancer Res. 2004 Jan 15;64(2):606-11. | ||||||||||
| Title: | herg1 gene and HERG1 protein are overexpressed in colorectal cancers and regulate cell invasion of tumor cells. | ||||||||||
| Author: | Lastraioli, Elena|Guasti, Leonardo|Crociani, Olivia|Polvani, Simone|Hofmann, Giovanna|Witchel, Harry|Bencini, Lapo|Calistri, Massimo|Messerini, Luca|Scatizzi, Marco|Moretti, Renato|Wanke, Enzo|Olivotto, Massimo|Mugnai, Gabriele|Arcangeli, Annarosa | ||||||||||
| PMID: | 14744775 | ||||||||||
| 2. | |||||||||||
| Journal: | Ai Zheng. 2005 Aug;24(8):924-9. | ||||||||||
| Title: | [Correlation of HERG K+ channel protein expression to chemosensitivity of tumor cells to doxorubicin and its modulation by erythromycin]. | ||||||||||
| Author: | Chen, Shu-Zhen|Jiang, Min|Zhen, Yong-Su | ||||||||||
| PMID: | 16086867 | ||||||||||
| 3. | |||||||||||
| Journal: | Zhonghua Yi Xue Za Zhi. 2006 Dec 19;86(47):3353-7. | ||||||||||
| Title: | [Erythromycin inhibits the proliferation of HERG K+ channel highly expressing cancer cells and shows synergy with anticancer drugs]. | ||||||||||
| Author: | Chen, Shu-zhen|Zhang, Sheng-hua|Gong, Jian-hua|Zhen, Yong-su | ||||||||||
| PMID: | 17313833 | ||||||||||
| 4. | |||||||||||
| Journal: | Transl Oncogenomics. 2007 Feb 14;2:1-16. Print 2007. | ||||||||||
| Title: | In Silico Promoter Analysis can Predict Genes of Functional Relevance in Cell Proliferation: Validation in a Colon Cancer Model. | ||||||||||
| Author: | Moss, Alan C|Doran, Peter P|Macmathuna, Padraic | ||||||||||
| PMID: | 23641142 | ||||||||||
| 5. | |||||||||||
| Journal: | Eur J Surg Oncol. 2010 Jan;36(1):72-7. | ||||||||||
| Title: | HERG1 gene expression as a specific tumor marker in colorectal tissues. | ||||||||||
| Author: | Dolderer, J H|Schuldes, H|Bockhorn, H|Altmannsberger, M|Lambers, C|von Zabern, D|Jonas, D|Schwegler, H|Linke, R|Schroder, U H | ||||||||||
| PMID: | 19577877 | ||||||||||
| 6. | |||||||||||
| Journal: | Oncol Rep. 2010 Jun;23(6):1747-56. | ||||||||||
| Title: | HERG K+ channel related chemosensitivity to sparfloxacin in colon cancer cells. | ||||||||||
| Author: | Gong, Jian-Hua|Liu, Xiu-Jun|Shang, Bo-Yang|Chen, Shu-Zhen|Zhen, Yong-Su | ||||||||||
| PMID: | 20428834 | ||||||||||
| 7. | |||||||||||
| Journal: | J Med Chem. 2011 Jan 27;54(2):580-90. | ||||||||||
| Title: | Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. | ||||||||||
| Author: | Caldwell, John J|Welsh, Emma J|Matijssen, Cornelis|Anderson, Victoria E|Antoni, Laurent|Boxall, Kathy|Urban, Frederique|Hayes, Angela|Raynaud, Florence I|Rigoreau, Laurent J M|Raynham, Tony|Aherne, G Wynne|Pearl, Laurence H|Oliver, Antony W|Garrett, Miche | ||||||||||
| PMID: | 21186793 | ||||||||||
| 8. | |||||||||||
| Journal: | Yao Xue Xue Bao. 2011 Nov;46(11):1321-5. | ||||||||||
| Title: | [Lidamycin inhibits the proliferation of HERG K+ channel highly expressing cancer cells and shows synergy with anticancer drugs]. | ||||||||||
| Author: | Shang, Bo-yang|Shang, Yue|Zhen, Yong-su|Chen, Shu-zhen | ||||||||||
| PMID: | 22260022 | ||||||||||
| 9. | |||||||||||
| Journal: | Transl Oncol. 2012 Apr;5(2):105-12. Epub 2012 Apr 1. | ||||||||||
| Title: | hERG1 Channels and Glut-1 as Independent Prognostic Indicators of Worse Outcome in Stage I and II Colorectal Cancer: A Pilot Study. | ||||||||||
| Author: | Lastraioli, Elena|Bencini, Lapo|Bianchini, Elisa|Romoli, Maria Raffaella|Crociani, Olivia|Giommoni, Elisa|Messerini, Luca|Gasperoni, Silvia|Moretti, Renato|Di Costanzo, Francesco|Boni, Luca|Arcangeli, Annarosa | ||||||||||
| PMID: | 22496927 | ||||||||||
| 10. | |||||||||||
| Journal: | Sci Rep. 2013 Nov 25;3:3308. | ||||||||||
| Title: | hERG1 channels modulate integrin signaling to trigger angiogenesis and tumor progression in colorectal cancer. | ||||||||||
| Author: | Crociani, Olivia|Zanieri, Francesca|Pillozzi, Serena|Lastraioli, Elena|Stefanini, Matteo|Fiore, Antonella|Fortunato, Angelo|D'Amico, Massimo|Masselli, Marika|De Lorenzo, Emanuele|Gasparoli, Luca|Chiu, Martina|Bussolati, Ovidio|Becchetti, Andrea|Arcangeli, | ||||||||||
| PMID: | 24270902 | ||||||||||
| 11. | |||||||||||
| Journal: | Cancer Med. 2013 Oct;2(5):583-94. | ||||||||||
| Title: | Characterization of hERG1 channel role in mouse colorectal carcinogenesis. | ||||||||||
| Author: | Fiore, Antonella|Carraresi, Laura|Morabito, Angela|Polvani, Simone|Fortunato, Angelo|Lastraioli, Elena|Femia, Angelo P|De Lorenzo, Emanuele|Caderni, Giovanna|Arcangeli, Annarosa | ||||||||||
| PMID: | 24403225 | ||||||||||
| 12. | |||||||||||
| Journal: | J Med Chem. 2013 Dec 12;56(23):9496-508. | ||||||||||
| Title: | High-throughput virtual screening identifies novel N'-(1-phenylethylidene)-benzohydrazides as potent, specific, and reversible LSD1 inhibitors. | ||||||||||
| Author: | Sorna, Venkataswamy|Theisen, Emily R|Stephens, Bret|Warner, Steven L|Bearss, David J|Vankayalapati, Hariprasad|Sharma, Sunil | ||||||||||
| PMID: | 24237195 | ||||||||||
| 13. | |||||||||||
| Journal: | Diagn Mol Pathol. 2013 Dec;22(4):215-21. | ||||||||||
| Title: | An analytical method for the quantification of hERG1 channel gene expression in human colorectal cancer. | ||||||||||
| Author: | Fortunato, Angelo|Gasparoli, Luca|Falsini, Sara|Boni, Luca|Arcangeli, Annarosa | ||||||||||
| PMID: | 24193004 | ||||||||||
| 14. | |||||||||||
| Journal: | J Exp Clin Cancer Res. 2014 Jan 9;33:6. | ||||||||||
| Title: | Characterization of the biological activity of a potent small molecule Hec1 inhibitor TAI-1. | ||||||||||
| Author: | Huang, Lynn Y L|Lee, Ying-Shuan|Huang, Jiann-Jyh|Chang, Chia-chi|Chang, Jia-Ming|Chuang, Shih-Hsien|Kao, Kuo-Jang|Tsai, Yung-Jen|Tsai, Pei-Yi|Liu, Chia-Wei|Lin, Her-Sheng|Lau, Johnson Y N | ||||||||||
| PMID: | 24401611 | ||||||||||
| 15. | |||||||||||
| Journal: | Eur J Med Chem. 2014 Apr 9;76:155-69. | ||||||||||
| Title: | Design and synthesis of potent antitumor water-soluble phenyl N-mustard-benzenealkylamide conjugates via a bioisostere approach. | ||||||||||
| Author: | Tala, Satishkumar D|Ou, Tai-Hsin|Lin, Yi-Wen|Tala, Kiranben S|Chao, Shu-Hsin|Wu, Ming-Hsi|Tsai, Tung-Hu|Kakadiya, Rajesh|Suman, Sharda|Chen, Ching-Huang|Lee, Te-Chang|Su, Tsann-Long | ||||||||||
| PMID: | 24583355 | ||||||||||
| 16. | |||||||||||
| Journal: | J Med Chem. 2014 Jul 24;57(14):6083-91. | ||||||||||
| Title: | 2',6'-Dihalostyrylanilines, pyridines, and pyrimidines for the inhibition of the catalytic subunit of methionine S-adenosyltransferase-2. | ||||||||||
| Author: | Sviripa, Vitaliy M|Zhang, Wen|Balia, Andrii G|Tsodikov, Oleg V|Nickell, Justin R|Gizard, Florence|Yu, Tianxin|Lee, Eun Y|Dwoskin, Linda P|Liu, Chunming|Watt, David S | ||||||||||
| PMID: | 24950374 | ||||||||||
| 17. | |||||||||||
| Journal: | Cancer Res. 2016 Feb 1;76(3):607-18. | ||||||||||
| Title: | SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness. | ||||||||||
| Author: | Crottes, David|Rapetti-Mauss, Raphael|Alcaraz-Perez, Francisca|Tichet, Melanie|Gariano, Giuseppina|Martial, Sonia|Guizouarn, Helene|Pellissier, Bernard|Loubat, Agnes|Popa, Alexandra|Paquet, Agnes|Presta, Marco|Tartare-Deckert, Sophie|Cayuela, Maria Luisa| | ||||||||||
| PMID: | 26645564 | ||||||||||
| 18. | |||||||||||
| Journal: | ACS Med Chem Lett. 2016 Jan 20;7(3):245-9. | ||||||||||
| Title: | Astemizole Derivatives as Fluorescent Probes for hERG Potassium Channel Imaging. | ||||||||||
| Author: | Wang, Beilei|Liu, Zhenzhen|Ma, Zhao|Li, Minyong|Du, Lupei | ||||||||||
| PMID: | 26985309 | ||||||||||
| 19. | |||||||||||
| Journal: | Onco Targets Ther. 2016 Oct 14;9:6325-6332. | ||||||||||
| Title: | hERG1 positivity and Glut-1 negativity identifies high-risk TNM stage I and II colorectal cancer patients, regardless of adjuvant chemotherapy. | ||||||||||
| Author: | Muratori, Leonardo|Petroni, Giulia|Antonuzzo, Lorenzo|Boni, Luca|Iorio, Jessica|Lastraioli, Elena|Bartoli, Gianluca|Messerini, Luca|Di Costanzo, Francesco|Arcangeli, Annarosa | ||||||||||
| PMID: | 27789963 | ||||||||||
| 20. | |||||||||||
| Journal: | Front Pharmacol. 2017 May 5;8:238. | ||||||||||
| Title: | Mode of Action Analyses of Neferine, a Bisbenzylisoquinoline Alkaloid of Lotus (Nelumbo nucifera) against Multidrug-Resistant Tumor Cells. | ||||||||||
| Author: | Kadioglu, Onat|Law, Betty Y K|Mok, Simon W F|Xu, Su-Wei|Efferth, Thomas|Wong, Vincent K W | ||||||||||
| PMID: | 28529482 | ||||||||||
| 21. | |||||||||||
| Journal: | Cell Oncol (Dordr). 2017 Aug;40(4):367-378. | ||||||||||
| Title: | The role of hERG1 ion channels in epithelial-mesenchymal transition and the capacity of riluzole to reduce cisplatin resistance in colorectal cancer cells. | ||||||||||
| Author: | Fortunato, Angelo | ||||||||||
| PMID: | 28593575 | ||||||||||
| 22. | |||||||||||
| Journal: | Br J Cancer. 2018 Jan;118(2):200-212. | ||||||||||
| Title: | The combined activation of KCa3.1 and inhibition of Kv11.1/hERG1 currents contribute to overcome Cisplatin resistance in colorectal cancer cells. | ||||||||||
| Author: | Pillozzi, Serena|D'Amico, Massimo|Bartoli, Gianluca|Gasparoli, Luca|Petroni, Giulia|Crociani, Olivia|Marzo, Tiziano|Guerriero, Angela|Messori, Luigi|Severi, Mirko|Udisti, Roberto|Wulff, Heike|Chandy, K George|Becchetti, Andrea|Arcangeli, Annarosa | ||||||||||
| PMID: | 29161243 | ||||||||||