Primary Site >> Colorectal Cancer
Gene >> KCNH2
|
|
|
|
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|---|---|
|
Ref: herg1 gene and HERG1 protein are overexpressed in colorectal cancers and regulate cell invasion of tumor cells. PMID: 14744775 |
Ref: [Correlation of HERG K+ channel protein expression to chemosensitivity of tumor cells to doxorubicin and its modulation by erythromycin]. PMID: 16086867 |
Ref: [Erythromycin inhibits the proliferation of HERG K+ channel highly expressing cancer cells and shows synergy with anticancer drugs]. PMID: 17313833 |
Ref: In Silico Promoter Analysis can Predict Genes of Functional Relevance in Cell Proliferation: Validation in a Colon Cancer Model. PMID: 23641142 |
Ref: HERG1 gene expression as a specific tumor marker in colorectal tissues. PMID: 19577877 Ref: HERG K+ channel related chemosensitivity to sparfloxacin in colon cancer cells. PMID: 20428834 |
Ref: Structure-based design of potent and selective 2-(quinazolin-2-yl)phenol inhibitors of checkpoint kinase 2. PMID: 21186793 Ref: [Lidamycin inhibits the proliferation of HERG K+ channel highly expressing cancer cells and shows synergy with anticancer drugs]. PMID: 22260022 |
Ref: hERG1 Channels and Glut-1 as Independent Prognostic Indicators of Worse Outcome in Stage I and II Colorectal Cancer: A Pilot Study. PMID: 22496927 |
Ref: An analytical method for the quantification of hERG1 channel gene expression in human colorectal cancer. PMID: 24193004 Ref: High-throughput virtual screening identifies novel N'-(1-phenylethylidene)-benzohydrazides as potent, specific, and reversible LSD1 inhibitors. PMID: 24237195 Ref: hERG1 channels modulate integrin signaling to trigger angiogenesis and tumor progression in colorectal cancer. PMID: 24270902 Ref: Characterization of hERG1 channel role in mouse colorectal carcinogenesis. PMID: 24403225 |
Ref: Characterization of the biological activity of a potent small molecule Hec1 inhibitor TAI-1. PMID: 24401611 Ref: Design and synthesis of potent antitumor water-soluble phenyl N-mustard-benzenealkylamide conjugates via a bioisostere approach. PMID: 24583355 Ref: 2',6'-Dihalostyrylanilines, pyridines, and pyrimidines for the inhibition of the catalytic subunit of methionine S-adenosyltransferase-2. PMID: 24950374 |
Ref: SIGMAR1 Regulates Membrane Electrical Activity in Response to Extracellular Matrix Stimulation to Drive Cancer Cell Invasiveness. PMID: 26645564 Ref: Astemizole Derivatives as Fluorescent Probes for hERG Potassium Channel Imaging. PMID: 26985309 Ref: hERG1 positivity and Glut-1 negativity identifies high-risk TNM stage I and II colorectal cancer patients, regardless of adjuvant chemotherapy. PMID: 27789963 |
Ref: Mode of Action Analyses of Neferine, a Bisbenzylisoquinoline Alkaloid of Lotus (Nelumbo nucifera) against Multidrug-Resistant Tumor Cells. PMID: 28529482 Ref: The role of hERG1 ion channels in epithelial-mesenchymal transition and the capacity of riluzole to reduce cisplatin resistance in colorectal cancer cells. PMID: 28593575 |
Ref: The combined activation of KCa3.1 and inhibition of Kv11.1/hERG1 currents contribute to overcome Cisplatin resistance in colorectal cancer cells. PMID: 29161243 |