Primary Site >> Pancreatic Cancer
Gene >> JAK1
| 1. | |||||||||||
| Journal: | Anticancer Res. 2011 Jun;31(6):2029-35. | ||||||||||
| Title: | LLL12 inhibits endogenous and exogenous interleukin-6-induced STAT3 phosphorylation in human pancreatic cancer cells. | ||||||||||
| Author: | Liu, Aiguo|Liu, Yan|Li, Pui-Kai|Li, Chenglong|Lin, Jiayuh | ||||||||||
| PMID: | 21737619 | ||||||||||
| 2. | |||||||||||
| Journal: | Gut Liver. 2012 Oct;6(4):417-22. | ||||||||||
| Title: | Role of janus kinase/signal transducers and activators of transcription in the pathogenesis of pancreatitis and pancreatic cancer. | ||||||||||
| Author: | Yu, Ji Hoon|Kim, Hyeyoung | ||||||||||
| PMID: | 23170143 | ||||||||||
| 3. | |||||||||||
| Journal: | Clin Cancer Res. 2013 Apr 15;19(8):1933-40. | ||||||||||
| Title: | Molecular pathways: Jak/STAT pathway: mutations, inhibitors, and resistance. | ||||||||||
| Author: | Quintas-Cardama, Alfonso|Verstovsek, Srdan | ||||||||||
| PMID: | 23406773 | ||||||||||
| 4. | |||||||||||
| Journal: | J Pathol. 2014 Mar;232(4):428-35. | ||||||||||
| Title: | Whole-exome sequencing of pancreatic neoplasms with acinar differentiation. | ||||||||||
| Author: | Jiao, Yuchen|Yonescu, Raluca|Offerhaus, G Johan A|Klimstra, David S|Maitra, Anirban|Eshleman, James R|Herman, James G|Poh, Weijie|Pelosof, Lorraine|Wolfgang, Christopher L|Vogelstein, Bert|Kinzler, Kenneth W|Hruban, Ralph H|Papadopoulos, Nickolas|Wood, La | ||||||||||
| PMID: | 24293293 | ||||||||||
| 5. | |||||||||||
| Journal: | Oncotarget. 2015 Apr 10;6(10):7504-21. | ||||||||||
| Title: | TCGA data and patient-derived orthotopic xenografts highlight pancreatic cancer-associated angiogenesis. | ||||||||||
| Author: | Gore, Jesse|Craven, Kelly E|Wilson, Julie L|Cote, Gregory A|Cheng, Monica|Nguyen, Hai V|Cramer, Harvey M|Sherman, Stuart|Korc, Murray | ||||||||||
| PMID: | 25762644 | ||||||||||
| 6. | |||||||||||
| Journal: | Virology. 2015 Nov;485:340-54. | ||||||||||
| Title: | Breaking resistance of pancreatic cancer cells to an attenuated vesicular stomatitis virus through a novel activity of IKK inhibitor TPCA-1. | ||||||||||
| Author: | Cataldi, Marcela|Shah, Nirav R|Felt, Sebastien A|Grdzelishvili, Valery Z | ||||||||||
| PMID: | 26331681 | ||||||||||
| 7. | |||||||||||
| Journal: | J Clin Oncol. 2015 Dec 1;33(34):4039-47. | ||||||||||
| Title: | Randomized, Double-Blind, Phase II Study of Ruxolitinib or Placebo in Combination With Capecitabine in Patients With Metastatic Pancreatic Cancer for Whom Therapy With Gemcitabine Has Failed. | ||||||||||
| Author: | Hurwitz, Herbert I|Uppal, Nikhil|Wagner, Stephanie A|Bendell, Johanna C|Beck, J Thaddeus|Wade, Seaborn M 3rd|Nemunaitis, John J|Stella, Philip J|Pipas, J Marc|Wainberg, Zev A|Manges, Robert|Garrett, William M|Hunter, Deborah S|Clark, Jason|Leopold, Lance| | ||||||||||
| PMID: | 26351344 | ||||||||||
| 8. | |||||||||||
| Journal: | Oncotarget. 2016 Sep 20;7(38):61601-61618. | ||||||||||
| Title: | Novel biomarkers of resistance of pancreatic cancer cells to oncolytic vesicular stomatitis virus. | ||||||||||
| Author: | Hastie, Eric|Cataldi, Marcela|Moerdyk-Schauwecker, Megan J|Felt, Sebastien A|Steuerwald, Nury|Grdzelishvili, Valery Z | ||||||||||
| PMID: | 27533247 | ||||||||||
| 9. | |||||||||||
| Journal: | Gene. 2016 Mar 10;578(2):263-73. | ||||||||||
| Title: | Microarray-based gene expression profiling reveals genes and pathways involved in the oncogenic function of REG3A on pancreatic cancer cells. | ||||||||||
| Author: | Xu, Qianqian|Fu, Rong|Yin, Guoxiao|Liu, Xiulan|Liu, Yang|Xiang, Ming | ||||||||||
| PMID: | 26719042 | ||||||||||
| 10. | |||||||||||
| Journal: | Pancreas. 2016 Mar;45(3):409-19. | ||||||||||
| Title: | Blockage of STAT3 Signaling Pathway by Morusin Induces Apoptosis and Inhibits Invasion in Human Pancreatic Tumor Cells. | ||||||||||
| Author: | Kim, Chulwon|Kim, Jin Ho|Oh, Eun Young|Nam, Dongwoo|Lee, Seok Geun|Lee, Junhee|Kim, Sung-Hoon|Shim, Bum Sang|Ahn, Kwang Seok | ||||||||||
| PMID: | 26646273 | ||||||||||
| 11. | |||||||||||
| Journal: | Oncotarget. 2016 Jan 5;7(1):323-41. | ||||||||||
| Title: | Angiogenic gene signature in human pancreatic cancer correlates with TGF-beta and inflammatory transcriptomes. | ||||||||||
| Author: | Craven, Kelly E|Gore, Jesse|Wilson, Julie L|Korc, Murray | ||||||||||
| PMID: | 26586478 | ||||||||||
| 12. | |||||||||||
| Journal: | Mol Cancer Res. 2017 Apr;15(4):478-488. | ||||||||||
| Title: | Potent EMT and CSC Phenotypes Are Induced By Oncostatin-M in Pancreatic Cancer. | ||||||||||
| Author: | Smigiel, Jacob M|Parameswaran, Neetha|Jackson, Mark W | ||||||||||
| PMID: | 28053127 | ||||||||||
| 13. | |||||||||||
| Journal: | Sci Rep. 2017 May 11;7(1):1787. | ||||||||||
| Title: | Inhibition of Jak/STAT signaling reduces the activation of pancreatic stellate cells in vitro and limits caerulein-induced chronic pancreatitis in vivo. | ||||||||||
| Author: | Komar, Hannah M|Serpa, Gregory|Kerscher, Claire|Schwoegl, Erin|Mace, Thomas A|Jin, Ming|Yang, Ming-Chen|Chen, Ching-Shih|Bloomston, Mark|Ostrowski, Michael C|Hart, Phil A|Conwell, Darwin L|Lesinski, Gregory B | ||||||||||
| PMID: | 28496202 | ||||||||||
| 14. | |||||||||||
| Journal: | J Virol. 2017 Jul 27;91(16). pii: JVI.00461-17. | ||||||||||
| Title: | Ruxolitinib and Polycation Combination Treatment Overcomes Multiple Mechanisms of Resistance of Pancreatic Cancer Cells to Oncolytic Vesicular Stomatitis Virus. | ||||||||||
| Author: | Felt, Sebastien A|Droby, Gaith N|Grdzelishvili, Valery Z | ||||||||||
| PMID: | 28566376 | ||||||||||
| 15. | |||||||||||
| Journal: | Oncol Rep. 2017 Aug;38(2):1075-1082. | ||||||||||
| Title: | MicroRNA-448 suppresses metastasis of pancreatic ductal adenocarcinoma through targeting JAK1/STAT3 pathway. | ||||||||||
| Author: | Yu, Dan-Li|Zhang, Tao|Wu, Kun|Li, Yan|Wang, Juan|Chen, Jun|Li, Xiao-Quan|Peng, Xing-Guo|Wang, Jia-Ning|Tan, Li-Guo | ||||||||||
| PMID: | 28677798 | ||||||||||
| 16. | |||||||||||
| Journal: | World J Gastroenterol. 2017 Dec 7;23(45):7945-7951. | ||||||||||
| Title: | Pancreatic acinar cell carcinoma: A review on molecular profiling of patient tumors. | ||||||||||
| Author: | Al-Hader, Ahmad|Al-Rohil, Rami N|Han, Haiyong|Von Hoff, Daniel | ||||||||||
| PMID: | 29259370 | ||||||||||
| 17. | |||||||||||
| Journal: | Invest New Drugs. 2018 Aug;36(4):683-695. | ||||||||||
| Title: | Ruxolitinib + capecitabine in advanced/metastatic pancreatic cancer after disease progression/intolerance to first-line therapy: JANUS 1 and 2 randomized phase III studies. | ||||||||||
| Author: | Hurwitz, Herbert|Van Cutsem, Eric|Bendell, Johanna|Hidalgo, Manuel|Li, Chung-Pin|Salvo, Marcelo Garrido|Macarulla, Teresa|Sahai, Vaibhav|Sama, Ashwin|Greeno, Edward|Yu, Kenneth H|Verslype, Chris|Dawkins, Fitzroy|Walker, Chris|Clark, Jason|O'Reilly, Eileen | ||||||||||
| PMID: | 29508247 | ||||||||||
| 18. | |||||||||||
| Journal: | Curr Cancer Drug Targets. 2018 Apr 30. pii: CCDT-EPUB-90071. | ||||||||||
| Title: | Blocking IL-6/GP130 signaling inhibits cell viability/proliferation, glycolysis, and colony forming activity in human pancreatic cancer cells. | ||||||||||
| Author: | Chen, Xiang|Tian, Jilai|Su, Gloria H|Lin, Jiayuh | ||||||||||
| PMID: | 29714141 | ||||||||||
| 19. | |||||||||||
| Journal: | Onco Targets Ther. 2018 Apr 30;11:2399-2407. | ||||||||||
| Title: | A Phase Ib study of ruxolitinib + gemcitabine +/- nab-paclitaxel in patients with advanced solid tumors. | ||||||||||
| Author: | Bauer, Todd M|Patel, Manish R|Forero-Torres, Andres|George, Thomas J Jr|Assad, Albert|Du, Yining|Hurwitz, Herbert | ||||||||||
| PMID: | 29750040 | ||||||||||
| 20. | |||||||||||
| Journal: | Invest New Drugs. 2018 Jul 30. pii: 10.1007/s10637-018-0650-5. | ||||||||||
| Title: | Phase 1 dose-escalation study of momelotinib, a Janus kinase 1/2 inhibitor, combined with gemcitabine and nab-paclitaxel in patients with previously untreated metastatic pancreatic ductal adenocarcinoma. | ||||||||||
| Author: | Ng, Kimmie|Hendifar, Andrew|Starodub, Alexander|Chaves, Jorge|Yang, Yingsi|Koh, Brian|Barbie, David|Hahn, William C|Fuchs, Charles S | ||||||||||
| PMID: | 30105668 | ||||||||||
| 21. | |||||||||||
| Journal: | Oncologist. 2018 Aug 16. pii: theoncologist.2017-0665. | ||||||||||
| Title: | A Phase Ib/II Study of the JAK1 Inhibitor, Itacitinib, plus nab-Paclitaxel and Gemcitabine in Advanced Solid Tumors. | ||||||||||
| Author: | Beatty, Gregory L|Shahda, Safi|Beck, Thaddeus|Uppal, Nikhil|Cohen, Steven J|Donehower, Ross|Gabayan, Afshin Eli|Assad, Albert|Switzky, Julie|Zhen, Huiling|Von Hoff, Daniel D | ||||||||||
| PMID: | 30115734 | ||||||||||